Anti-Inflammatory Effects of Siegesbeckia orientalis Ethanol Extract in In Vitro and in Vivo Models

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Hong, Yong Han ^a   Weng, Li Wen ^a   Chang, Chi Chang ^a   Hsu, Hsia Fen ^a   Wang, C Ping ^a   Wang, Shih Wei ^a   Houng, Jer Yiing ^a  

^a I SHOU UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PLANT EXTRACT; SIEGESBECKIA ORIENTALIS EXTRACT; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ALCOHOL; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARRAGEENAN-INDUCED PAW EDEMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG MEGADOSE; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; INTERFERON PRODUCTION; MEDICINAL PLANT; MOUSE; NONHUMAN; PROTEIN DEGRADATION; SIEGESBECKIA ORIENTALIS; SURVIVAL; SURVIVAL RATE; ANIMAL; ASTERACEAE; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; IMMUNOLOGY; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; MACROPHAGE; PATHOLOGY; TREATMENT OUTCOME;

ANIMALIA; MUS; SIEGESBECKIA ORIENTALIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTERACEAE; CELL LINE; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FEMALE; INFLAMMATION; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; PLANT EXTRACTS; TREATMENT OUTCOME;

EID: 84930903057     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/329712     Document Type: Article

References (33)

1. P. Libby, "Inflammation and cardiovascular disease mechanisms, " The American Journal of Clinical Nutrition, vol. 83, no. 2, pp. 456-460, 2006.
2. S. E. Shoelson, L. Herrero, and A. Naaz, "Obesity, inflammation, and insulin resistance, " Gastroenterology, vol. 132, no. 6, pp. 2169-2180, 2007.
3. W. Lin and M. Karin, "A cytokine-mediated link between innate immunity, inflammation, and cancer, " Journal of Clinical Investigation, vol. 117, no. 5, pp. 1175-1183, 2007.
4. U. N. Das, "Critical advances in septicemia and septic shock, " Critical Care, vol. 4, no. 5, pp. 290-296, 2000.
5. A. Azzolina, A. Bongiovanni, and N. Lampiasi, "Substance P induces TNF-β and IL-6 production through NFκB in peritoneal mast cells, " Biochimica et Biophysica Acta: Molecular Cell Research, vol. 1643, no. 1-3, pp. 75-83, 2003.
6. J. J. Baldassare, Y. Bi, andC. J. Bellone, "The role of p38mitogenactivated protein kinase in IL-1β transcription, " Journal of Immunology, vol. 162, no. 9, pp. 5367-5373, 1999.
7. U. Singh, J. Tabibian, S. K. Venugopal, S. Devaraj, and I. Jialal, "Development of an in vitro screening assay to test the antiinflammatory properties of dietary supplements and pharmacologic agents, " Clinical Chemistry, vol. 51, no. 12, pp. 2252-2256, 2005.
8. S. Kanoh and B. K. Rubin, "Mechanisms of action and clinical application of macrolides as immunomodulatory medications, " Clinical Microbiology Reviews, vol. 23, no. 3, pp. 590-615, 2010.
9. S. Bhattacharyya, P. K. Dudeja, and J. K. Tobacman, "Carrageenan-induced NF-κB activation depends on distinct pathways mediated by reactive oxygen species and Hsp27 or by Bcl10, " Biochimica et Biophysica Acta-General Subjects, vol. 1780, no. 7-8, pp. 973-982, 2008.
10. M. M. Chan, H. Huang, M. R. Fenton, and D. Fong, "In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties, " Biochemical Pharmacology, vol. 55, no. 12, pp. 1955-1962, 1998.
11. J. H. OKeefe, N. M. Gheewala, and J. O. OKeefe, "Dietary strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health, " Journal of the American College of Cardiology, vol. 51, no. 3, pp. 249-255, 2008.
12. J. Xiong, Y. Ma, and Y. Xu, "Diterpenoids from Siegesbeckia pubescens, " Phytochemistry, vol. 31, no. 3, pp. 917-921, 1992.
13. R. Q. Qian, C. Y. Zhang, and H. Z. Fu, "Study on therapeutic mechanism of anti-rheumatism action of herba siegesbeckiae, " Chinese Journal of Integrated Traditional andWesternMedicine, vol. 20, no. 3, pp. 192-195, 2000.
14. W. Hwang, E. Park, C. Jang et al., "Inhibitory effect of immunoglobulin E production by Jin-deuk-chal (Siegesbeckia orientalis), " Immunopharmacology and Immunotoxicology, vol. 23, no. 4, pp. 555-563, 2001.
15. H. Sun and H. Wang, "Immunosuppressive activity of the ethanol extract of Siegesbeckia orientalis on the immune responses to ovalbumin in mice, " Chemistry and Biodiversity, vol. 3, no. 7, pp. 754-761, 2006.
16. J. Wang, Y. Zhou, Y. Ye et al., "Topical anti-inflammatory and analgesic activity of kirenol isolated from Siegesbeckia orientalis, " Journal of Ethnopharmacology, vol. 137, no. 3, pp. 1089-1094, 2011.
17. H. F. Hsu, Z. H. Chen, S. F. Chang et al., "Evaluating the anti-metastatic potential of Anisomeles Indica extract by using human oral squamous carcinoma FaDu cells, "African Journal of Pharmacy and Pharmacology, vol. 6, no. 24, pp. 1782-1791, 2012.
18. National Research Council, "Animal environment, housing and management, " in Guide for the Care and Use of Laboratory Animals, pp. 21-55, National Academy Press, Washington, DC, USA, 1996.
19. Y. H. Hong, W. W. Chao, M. L. Chen, and B. F. Lin, "Ethyl acetate extracts of alfalfa (Medicago sativa L. ) sprouts inhibit lipopolysaccharide-induced inflammation in vitro and in vivo, " Journal of Biomedical Science, vol. 16, article 64, no. 1, 2009.
20. W. Chao, Y. Hong, M. Chen, and B. Lin, "Inhibitory effects of Angelica sinensis ethyl acetate extract and major compounds on NF-κB trans-activation activity and LPS-induced inflammation, " Journal of Ethnopharmacology, vol. 129, no. 2, pp. 244-249, 2010.
21. M. Lee, J. Lee, C. Seo et al., "Anti-inflammatory activity of Angelica dahurica ethanolic extract on RAW264. 7 cells via upregulation of heme oxygenase-1, " Food and Chemical Toxicology, vol. 49, no. 5, pp. 1047-1055, 2011.
22. A. K. Clark, E. A. Old, and M. Malcangio, "Neuropathic pain and cytokines: current perspectives, " Journal of Pain Research, vol. 6, pp. 803-814, 2013.
23. D. Laveti, M. Kumar, R. Hemalatha et al., "Anti-inflammatory treatments for chronic diseases: a review, " Inflammation and Allergy-Drug Targets, vol. 12, no. 5, pp. 349-361, 2013.
24. X. Ye, W. Zhou, Y. Li et al., "Darbufelone, a novel antiinfammatory drug, induces growth inhibition of lung cancer cells both in vitro and in vivo, " Cancer Chemotherapy and Pharmacology, vol. 66, no. 2, pp. 277-285, 2010.
25. H. Jung, U. Seo, J. Kim, K. Leem, and Y. Park, "Flower extract of Panax notoginseng attenuates lipopolysaccharide-induced inflammatory response via blocking of NF-κB signaling pathway in murine macrophages, " Journal of Ethnopharmacology, vol. 122, no. 2, pp. 313-319, 2009.
26. C. J. Morris, "Carrageenan-induced paw edema in the rat and mouse, " Methods in Molecular Biology, vol. 225, pp. 115-121, 2003.
27. H. Park, Y. H. Kim, H. W. Chang, and H. P. Kim, "Antiinflammatory activity of the synthetic C-C biflavonoids, " Journal of Pharmacy and Pharmacology, vol. 58, no. 12, pp. 1661-1667, 2006.
28. H. Lim, J. Yoon, Y. Kim, M. Lee, S. Park, and H. Choi, "Free radical-scavenging and inhibition of nitric oxide production by four grades of pine mushroom (Tricholoma matsutake Sing. ), " Food Chemistry, vol. 103, no. 4, pp. 1337-1342, 2007.
29. S. J. Wu, J. Y. Fang, C. C. Ng, C. Y. Wang, and Y. T. Shyu, "Anti-inflammatory activity of Lactobacillus-fermented adlaysoymilk in LPS-induced macrophages through suppression of NF-κB pathways, " Food Research International, vol. 52, no. 1, pp. 262-268, 2013.
30. T. D. Gilmore and M. R. Garbati, "Inhibition ofNF-κB signaling as a strategy in disease therapy, " Current Topics in Microbiology and Immunology, vol. 349, pp. 245-263, 2011.
31. K. M. Ardeshna, A. R. Pizzey, S. Devereux, and A. Khwaja, "The PI3 kinase, p38 SAP kinase, and NF-κb signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells, " Blood, vol. 96, no. 3, pp. 1039-1046, 2000.
32. K. Hochrainer, G. Racchumi, and J. Anrather, "Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment, " The Journal of Biological Chemistry, vol. 288, no. 1, pp. 285-293, 2013.
33. M. Guma and G. S. Firestein, "C-Jun N-terminal kinase in inflammation and rheumatic diseases, " Open Rheumatology Journal, vol. 6, no. 2, pp. 220-231, 2012.