Anti-inflammatory activity of Angelica dahurica ethanolic extract on RAW264.7 cells via upregulation of heme oxygenase-1

Food and Chemical Toxicology

Volumn 49, Issue 5, 2011, Pages 1047-1055

  Lee, Mee Young ^a   Lee, Jin Ah ^a   Seo, Chang Seob ^a   Ha, Heykyung ^a   Lee, Hoyoung ^a   Son, Jong Keun ^b   Shin, Hyeun Kyoo ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^b Yeungnam University   (South Korea)

Author keywords

Angelica dahurica; COX 2; HO 1; IL4; INOS

Indexed keywords

ALCOHOL; ANGELICA DAHURICA EXTRACT; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; HEME OXYGENASE 1; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; PLANT EXTRACT; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANGELICA; ANGELICA DAHURICA; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANGELICA; ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOKINES; HEME OXYGENASE-1; I-KAPPA B PROTEINS; INTERLEUKIN-4; INTERLEUKIN-5; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE PROTEINS; METALLOPORPHYRINS; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PROTOPORPHYRINS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

ANGELICA DAHURICA;

EID: 79953047271     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2011.01.010     Document Type: Article

References (29)

1. Aburaya M., Tanaka K., Hoshino T., Tsutsumi S., Suzuki K., Makise M., Akagi R., Mizushima T. Heme oxygenase-1 protects gastric mucosal cells against non-steroidal anti-inflammatory drugs. J. Biol. Chem. 2006, 281:33422-33432.
2. 2 production. Planta. Med. 2003, 69:408-412.
3. Calder P.C. Polyunsaturated fatty acids, inflammation, and immunity. Lipids 2001, 36:1007-1024.
4. Chung H.T., Pae H.O., Cha Y.N. Role of heme oxygenase-1 in vascular disease. Curr. Pharm. Des. 2008, 14:422-428.
5. Cuccurullo C., Fazia M.L., Mezzetti A., Cipollone F. COX-2 expression in atherosclerosis: the good, the bad or the ugly?. Cur. Med. Chem. 2007, 14:1595-1605.
6. Feldmann M., Brennan F.M., Maini R.N. Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 1996, 14:397-440.
7. Furst R., Blumenthal S.B., Kiemer A.K., Zahler S., Vollmar A.M. Nuclear factor-kappa B-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the c-jun N-terminal kinase/activator protein-1 pathway. J. Pharmacol. Exp. Ther. 2006, 318:389-394.
8. Gueler F., Park J.K., Rong S., Kirsch T., Lindschau C., Zheng W., Elger M., Fiebeler A., Fliser D., Luft R.C., Haller H. Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages. Am. J. Pathol. 2007, 170:1192-1199.
9. Helmer K.S., Suliburk J.W., Mercer D.W. Ketamine-induced gastroprotection during endotoxemia: role of heme-oxygenase-1. Dig. Dis. Sci. 2006, 51:1571-1581.
10. Jang S.I., Jeong S.I., Kim K.J., Kim H.J., Yu H.H., Park R.R., Kim H.M., You Y.O. Tanshinone IIA from Salvia miltiorrhiza inhibits inducible nitric oxide synthase expression and production of TNF-alpha, IL-1beta and IL-6 in activated RAW 264.7 cells. Planta. Med. 2003, 69:1057-1059.
11. Jiang D.J., Jiang J.L., Tan G.S., Huang Z.Z., Deng H.W., Li Y.J. Demethylbellidifolin inhibits adhesion of monocytes to endothelial cells via reduction of tumor necrosis factor alpha and endogenous nitric oxide synthase inhibitor level. Planta. Med. 2003, 69:1150-1152.
12. Klemm S., Ruland J. Inflammatory signal transduction from the Fc epsilon RI to NF-kappa B. Immunobiology 2006, 211:815-820.
13. Kwak H.J., Song J.S., No Z.S., Song J.H., Yang S.D., Cheon H.G. The inhibitory effects of roflumilast on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells are mediated by heme oxygenase-1 and its product carbon monoxide. Inflamm. Res. 2005, 54:508-513.
14. Lee S.H., Li G., Kim H.J., Kim J.Y., Chang H.W., Jahang Y., Woo M.H., Song D.K., Son J.K. Two new furanocoumarins from the roots of Angelica dahurica. Bull. Korean Chem. Soc. 2003, 24:1699-1701.
15. Leone S., Ottani A., Bertolini A. Dual acting anti-inflammatory drugs. Curr. Top. Med. Chem. 2007, 7:265-275.
16. Magnani M., Crinelli R., Bianchi M., Antonelli A. The ubiquitin-dependent proteolytic system and other potential targets for the modulation of nuclear factor-kB (NF-kB). Curr. Drug Targets 2000, 1:387-399.
17. Mendes S.D.S., Candi A., Vansteenbrugge M., Pignon M.R., Bult H., Boudjeltia K.Z.B., Munaut C., Taes M. Microarray analyses of the effects of NF-kappaB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells: synergistic effects of rapamycin on LPS-induced MMP9-overexpression. Cell Signal 2009, 21:1109-1122.
18. Oh S.G., Pae H.O., Lee B.S., Kim B.N., Kim J.M., Kim H.R., Jeon S.B., Jeon W.K., Chae H.J., Chung H.T. Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic. Biol. Med. 2006, 41:106-119.
19. Ohshima H., Tazawa H., Sylla B.S., Sawa T. Prevention of human cancer by modulation of chronic inflammatory processes. Mutat. Res. 2005, 591:110-122.
20. Pae H.O., Jeong S.O., Koo B.S., Ha H.Y., Lee K.M., Chung H.T. Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages. Biochem. Biophys. Res. Commun. 2008, 371:361-365.
21. Pae H.O., Lee R.C., Chung H.T. Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy. Recent. Pat. Inflamm. Allergy. Drug. Discov. 2008, 2:159-165.
22. 3H/HeJ and C57BL/10ScCr mice. Mutations in Tlr4 gene. Science 1998, 282:2085-2088.
23. Radtke O.A., Kiderlen A.F., Kayser O., Kolodziej H. Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid. Planta. Med. 2004, 70:924-928.
24. Rahman K.W., Sarkar F.H. Inhibition of nuclear translocation of nuclear factor-{kappa}B contributes to 3,3′-diindolylmethane-induced apoptosis in breast cancer cells. Cancer Res. 2005, 65:364-371.
25. Reed G.A., Arneson D.W., Putnam W.C., Smith H.J., Gray J.C., Sullivan D.K., Mayo M.S., Crowell J.A., Hurwitz A. Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3′-diindolylmethane. Cancer Epidemiol. Biomarkers Prev. 2006, 15:2477-2481.
26. Ross J.A., Auger M.J., Burke B., Lewis C.E. The biology of the macrophage. The Macrophage 2002, 1-72. Oxford Medical Publications, Oxford, UK. 2nd ed. B. Burke, C.E. Lewis (Eds.).
27. Uzbay I.T., Oglesby M.W. Nitric oxide and substance dependence. Neurosci. Biobehav. Rev. 2001, 25:43-52.
28. Won J.H., Kim J.Y., Yun K.J., Lee J.H., Back N.I., Chung H.G., Chung S.A., Jeong T.S., Choi M.S., Lee K.T. Gigantol isolated from the whole plants of Cymbidium goeringii inhibits the LPS-induced iNOS and COX-2 expression via NF-kappaB inactivation in RAW 264.7 macrophages cells. Planta. Med. 2006, 72:1181-1187.
29. Xia Z., Triffitt J.T. A review on macrophage response to biomaterials. Biomed. Mater. 2006, 1:R1-9.