Matrine inhibits the growth and induces apoptosis of osteosarcoma cells in vitro by inactivating the Akt pathway

Tumor Biology

Volumn 36, Issue 3, 2015, Pages 1653-1659

  Xu, Gong Ping ^a   Zhao, Wei ^a   Zhuang, Jin Peng ^a   Zu, Jia Ning ^a   Wang, Duan Yang ^a   Han, Fei ^a   Zhang, Zhi Peng ^a   Yan, Jing Long ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Akt pathway; Cell cycle arrest; Matrine; Osteosarcoma

Indexed keywords

ALKALOID; BAX PROTEIN, HUMAN; CDKN1B PROTEIN, HUMAN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MATRINE; PROTEIN BAX; PROTEIN KINASE B; QUINOLIZINE DERIVATIVE;

APOPTOSIS; BONE NEOPLASMS; CELL CYCLE G0 PHASE; CELL PROLIFERATION; DRUG EFFECTS; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; METABOLISM; OSTEOSARCOMA; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ALKALOIDS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BONE NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; G0 PHASE; G1 PHASE CELL CYCLE CHECKPOINTS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; OSTEOSARCOMA; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLIZINES; SIGNAL TRANSDUCTION;

EID: 84930895509     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2764-5     Document Type: Article

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