Cardioprotective effect of matrine on isoproterenol-induced cardiotoxicity in rats

Journal of Pharmacy and Pharmacology

Volumn 62, Issue 4, 2010, Pages 514-520

  Li, Xiaobing ^a   Zhou, Ru ^a   Zheng, Ping ^a   Yan, Lin ^a   Wu, Yang ^a,b   Xiao, Xu ^a   Dai, Guidong ^a,b  

^a NINGXIA MEDICAL UNIVERSITY   (China)

^b Ningxia Research Institute of Medicine and Pharmacy   (China)

Author keywords

Antioxidants; Cardioprotection; Cardiotoxicity; Isoproterenol; Matrine

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CATALASE; CREATINE KINASE; GLUTATHIONE PEROXIDASE; ISOPRENALINE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MATRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME RELEASE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE DYSFUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HISTOPATHOLOGY; LIPID PEROXIDATION; MALE; MYOCARDIAL DISEASE; NONHUMAN; RAT; SYSTOLIC BLOOD PRESSURE;

EID: 77952870009     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.62.04.0015     Document Type: Article

References (23)

1. Ma L et al. Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells Planta Med 2008 74 : 245 251.
2. Dai ZJ et al. Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3 J Ethnopharmacol 2009 123 : 91 96.
3. Zhang DH et al. The anti-arrhythmic effect of matrine Acta Pharmacol Sin 1990 11 : 253 257.
4. Cheng H et al. Matrine improves 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice Pharmacol Res 2006 53 : 202 208.
5. Zhang YJ et al. Effect of matrine and carvedilol on collagen and MMPs activity of hypertrophy myocardium induced by pressure overload J Zhejiang Univ Sci B 2006 7 : 245 250.
6. Li Y et al. Matrine induces apoptosis in angiotensin II-stimulated hyperplasia of cardiac fibroblasts: effects on Bcl-2/Bax expression and caspase-3 activation Basic Clin Pharmacol Toxicol 2007 101 : 1 8.
7. Ruan C et al. Effect of matrine on norepinephrine-induced hypertrophy and expression of myosin heavy chain genes in cultured rat cardiomyocytes J Clin Cardiol 2002 18 : 171 172.
8. Zhou Y et al. Inotropic effects and mechanisms of matrine, a main alkaloid from Sophora flavescens Ait Biol Pharm Bull 2008 31 : 2057 2062.
9. Wei JW et al. Cardiovascular effects of matrine isolated from the Chinese herb Shan-dou-gen Proc Natl Sci Counc Repub China B 1985 9 : 215 219.
10. Xu CQ et al. Comparison of the anti-arrhythmic effects of matrine and berbamine with amiodarone and RP58866 Yao Xue Xue Bao 2004 39 : 691 694.
11. Rona G Catecholamine cardiotoxicity J Mol Cell Cardiol 1985 17 : 291 300.
12. Rathore N et al. Lipid peroxidation and antioxidant enzymes in isoproterenol induced oxidative stress in rat tissues Pharmacol Res 1998 38 : 297 303. (Pubitemid 28466749)
13. Anandan R et al. Protective effect of n-3 polyunsaturated fatty acids concentrate on isoproterenol-induced myocardial infarction in rats Prostaglandins Leukot Essent Fatty Acids 2007 76 : 153 158.
14. Karthikeyan K et al. Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats Int J Cardiol 2007 115 : 326 333.
15. Yang C et al. Cadioprotective effect of matrine on myocardial ischemia in hypercholesterolemia rats Chinese Traditional Herb Drugs 2008 39 : 880 884.
16. Wang X et al. Protective effect of matrine on myocardial injury in hyperlipemia rats Huaxi Yao Xue Zha Zhi 2008 23 : 407 410.
17. Rajadurai M, Stanely Mainzen Prince P Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study Toxicology 2007 232 : 216 225.
18. Zhou R et al. Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat Eur J Pharmacol 2008 586 : 244 250.
19. Loh HK et al. Effects of thalidomide on isoprenaline-induced acute myocardial injury: a haemodynamic, histopathological and ultrastructural study Basic Clin Pharmacol Toxicol 2007 100 : 233 239.
20. Sabeena Farvin KH et al. Effect of squalene on tissue defense system in isoproterenol-induced myocardial infarction in rats Pharmacol Res 2004 50 : 231 236.
21. Zhou B et al. Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1 J Pharmacol Sci 2006 102 : 387 395.
22. Sawyer DB et al. Role of oxidative stress in myocardial hypertrophy and failure J Mol Cell Cardiol 2002 34 : 379 388.
23. Srivastava S et al. Downregulation of CuZn-superoxide dismutase contributes to beta-adrenergic receptor-mediated oxidative stress in the heart Cardiovasc Res 2007 74 : 445 455.