Excess prenatal corticosterone exposure results in albuminuria, sex-specific hypotension, and altered heart rate responses to restraint stress in aged adult mice

American Journal of Physiology - Renal Physiology

Volumn 308, Issue 10, 2015, Pages F1065-F1073

  O’Sullivan, Lee ^a   Cuffe, James S M ^a   Koning, Anselm ^a   Singh, Reetu R ^a   Paravicini, Tamara M ^a   Moritz, Karen M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Developmental programming; Glucocorticoid; Hypotension; Nephron deficit

Indexed keywords

ALBUMIN; ANGIOTENSIN 2 RECEPTOR; CORTICOSTERONE; CREATININE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; PROTEIN BAX; PROTEIN BCL 2; WNT4 PROTEIN;

ADULT; AGTR1A GENE; ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CREATININE URINE LEVEL; ELECTROLYTE URINE LEVEL; EMBRYO; FEMALE; FETUS; FETUS WEIGHT; GENE EXPRESSION; HEART RATE; HEART RATE VARIABILITY; HYPOTENSION; IMMOBILIZATION STRESS; KIDNEY MASS; MALE; MOUSE; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROGENY; REN 1 GENE; SEX DIFFERENCE; SODIUM URINE LEVEL; UPREGULATION; ADVERSE EFFECTS; AGE; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED; COMPARATIVE STUDY; COMPLICATION; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; EXERCISE; MENTAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE; TACHYCARDIA;

AGE FACTORS; ALBUMINURIA; ANIMALS; BLOOD PRESSURE; CORTICOSTERONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART RATE; HYPOTENSION; MALE; MICE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RESTRAINT, PHYSICAL; SEX FACTORS; STRESS, PSYCHOLOGICAL; TACHYCARDIA;

EID: 84930863473     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00676.2014     Document Type: Article

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