Haemodynamic characteristics of hypertension induced by prenatal cortisol exposure in sheep

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 10, 2009, Pages 981-987

  Moritz, Karen M ^a,c   Dodic, Miodrag ^b   Jefferies, Andrew J ^a,b   Marelyn Wintour, E ^a,b   Dematteo, Robert ^a,b   Singh, Reetu R ^a   Evans, Roger G ^b  

^a Department of Anatomy and Developmental Biology ^*  (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Autonomic nervous system; Cardiac output; Developmental programming; Sympathetic nervous system; Total peripheral resistance

Indexed keywords

ADRENERGIC RECEPTOR; CARBON MONOXIDE; DEXAMETHASONE; HEXAMETHONIUM; HYDROCORTISONE; PHENTOLAMINE; PROPRANOLOL; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CARBON MONOXIDE BLOOD LEVEL; CASTRATED FEMALE; CASTRATED MALE; CONTROLLED STUDY; DEPRESSOR RESPONSE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRENATAL DRUG EXPOSURE; PROGENY; SHEEP; SYSTEMIC VASCULAR RESISTANCE;

EID: 72449172071     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05180.x     Document Type: Article

References (42)

1. Barker DJ, Lackland DT. Prenatal influences on stroke mortality in England and Wales. Stroke 2003; 34: 1598-1602
2. Rich-Edwards JW, Stampfer MJ, Manson JE et al. Birth weight and risk of cardiovascular disease in a cohort of women, followed up since 1976. BMJ 1997; 315: 396-400.
3. McMillen IC, Robinson. JS. Developmental origins of the metabolic syndrome: Prediction, plasticity, and programming. Physiol. Rev. 2005; 85: 571-633.
4. Moritz K.M., Boon WM., Wintour EM. Glucocorticoid programming of adult disease. Cell Tissue Res. 2005; 322: 81-88
5. Ortiz LA, Quan A, Zarzar F, Weinberg A, Baum M. Prenatal dexamethasone programs hypertension and renal, injury in the rat. Hypertension 2003; 41: 328-334 (Pubitemid 36204910)
6. Singh RR, Cullen-McEwen. LA, Kett MM. et al. Prenatal corticosterone exposure results in altered AT1/AT2, nephron deficit and hypertension in the rat offspring. J. Physiol. 2007; 579: 503-513
7. Dodic M, May CN, Wintour EM, Coghlan JP. An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in. sheep. Clin. Sci. 1998; 94: 149-155 (Pubitemid 28052645)
8. Dodic M, Hantzis V, Duncan. J et al. Programming effects of short prenatal, exposure to Cortisol. FASEB J. 2002; 16: 1017-1026 (Pubitemid 34753508)
9. Dodic M, Peers A, Coghlan JP et al. Altered cardiovascular haemodynamics and baroreceptor-heart rate reflex in adult sheep after prenatal exposure to dexamethasone. Clin. Sci. 1999; 97:103-109 (Pubitemid 29353902)
10. Dodic M, Samuel. C, Moritz K et al. Impaired cardiac functional reserve and left ventricular hypertrophy in adult sheep after prenatal dexamethasone exposure. Circ. Res. 2001; 89: 623-629 (Pubitemid 32924217)
11. Dodic M, MeAlinden AT, Jefteries AJ et al. Differential effects of prenatal exposure to dexamethasone or Cortisol on circulatory control mechanisms mediated by angiotensin. II in the central, nervous system, of adult sheep. J. Physiol. 2006; 571: 651-660
12. Moritz KM, Johnson K, Douglas-Denton R, Wintour EM, Dodic M. Maternal glucocorticoid treatment programs alterations in the reninangiotensin system of the ovine fetal, kidney. Endocrinology 2002; 143: 4455-4463 (Pubitemid 35239580)
13. Wintour EM, Moritz KM, Johnson K, Ricardo S, Samuel CS, Dodic M. Reduced nephron number in adult sheep, hypertensive as a result of prenatal glucocorticoid treatment. J. Physiol. 2003; 549: 929-935 (Pubitemid 36889780)
14. Dodic M, Abouantoun T, O'Connor A, Wintour EM, Moritz KM, Programming effects of short prenatal exposure to dexamethasone in sheep. Hypertension 2002; 40: 729-734 (Pubitemid 35278611)
15. Opařil S, Zaman MA, Calhoun DA. Pathogenesis of hypertension. Ann. Intern. Med. 2003; 139: 761-776
16. Ventura HO, Taler SJ, Strobeck JE. Hypertension as a hemodynamic disease: The role of impedance cardiography in diagnostic, prognostic, and therapeutic decision making. Am. J. Hypenens. 2005; 18 (Suppl.): S26-43.
17. Phillips DI. Programming of the stress response: A fundamental, mechanism underlying the long-term effects of the fetal environment? J. Intern. Med. 2007; 261:453-460
18. Uzerman RG, Stehouwer CD, de Geus EJ, van Weissenbruch MM, Delemarre-van de Waal. HA, Boomsma DI. Low birth weight is associated with increased sympathetic activity: Dependence on genetic factors. Circulation 2003; 108: 566-571 (Pubitemid 36961171)
19. Ojeda NB, Johnson WR, Dwyer TM, Alexander BT. Early renal denervation prevents development of hypertension in growth-restricted offspring. Clin. Exp. Pharmacol. Physiol. 2007; 34:1212-1216
20. Ludbrook J. Comparing methods of measurements. Clin, Exp. Pharmacol. Physiol. 1997; 24: 193-203.
21. Ludbrook J. Repeated measurements and multiple comparisons in cardiovascular research. Cardiovasc. Res. 1994; 28: 303-311 (Pubitemid 24131066)
22. Barker DJ, Bagby SP. Developmental antecedents of cardiovascular disease: A historical, perspective. J. Am. Soc. Nephrol. 2005; 16: 2537-2544
23. Moritz KM, Bertram JF. Barker and Brenner: A basis for hypertension? Curr. Hypenens. Rev. 2006; 2:179-185
24. Schlaich MP, Lambert E, Kaye DM et al. Sympathetic augmentation in hypertension: Role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation. Hypertension 2004; 43: 169-175 (Pubitemid 38174169)
25. Grisk O, Rose HJ, Lorenz G, Rettig R. Sympathetic-renal interaction in chronic arterial pressure control. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002; 283: R441-50.
26. Esler M, Straznicky N, Eikelis N, Masuo K, Lambert G, Lambert E. Mechanisms of sympathetic activation in obesity-related hypertension. Hypertension 2006; 48: 787-796 (Pubitemid 44610980)
27. Johansson M, Elam M, Rundqvist B et al. Increased sympathetic nerve activity in renovascular hypertension. Circulation 1999; 99: 2537-2542 (Pubitemid 29228284)
28. Head GA, Burke SL. Sympathetic responses to stress and rilmenidine in 2K1C rabbits: Evidence of enhanced nonvascular effector mechanism. Hypertension. 2004; 43: 636-642
29. Li Q, Dale WE, Hasser EM, Blaine EH. Acute and chronic angiotensin hypertension. Neural and nonneural components, time course, and dose dependency. Am. J. Physiol. 1996; 271: R200-7.
30. Burke SL, Evans RG, Moretti. JL, Head GA. Levels of renal and extrarenal sympathetic drive in angiotensin II-induced hypertension. Hypertension. 2008; 51: 878-883
31. Diedrich A, Jordan J, Tank J et al. The sympathetic nervous system, in. hypertension: Assessment by blood pressure variability and ganglionic blockade. J. Hyperliens. 2003; 21: 1677-1686 (Pubitemid 37076351)
32. Kliewer SA, Goodwin B, Willson TM. The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism. Endocr. Rev. 2002; 23: 687-702. (Pubitemid 35191629)
33. Rogerson FM, Yao YZ, Smith BJ, Dimopoulos N, Fuller PJ. Determinants of spironolactone binding specificity in the mineralocorticoid receptor. J. MoI Endocrinol. 2003; 31: 573-582 (Pubitemid 38054527)
34. Lu NZ, Cidlowski JA. The origin and functions of multiple human glucocorticoid receptor isoforms. Ann. N.Y. Acad. Sci. 2004; 1024:102-123 (Pubitemid 38879596)
35. De Blasio MJ, Dodic M, Jefferies AJ, Moritz KM, Wintour EM, Owens JA. Maternal exposure to dexamethasone or Cortisol in early pregnancy differentially alters insulin secretion and glucose homeostasis in adult male sheep offspring. Am. J. Physiol. Endocrinol. Metab. 2007; 293: E75-82.
36. Moritz KM,Wintour EM, Bertram JF, Bartal D, Dodic M. Reduced glomerular number and altered expression of sodiu,m, channels after early prenatal glucocorticoid treatment. J. Soc. Gynecol. Invest. 2005; 12 (Suppl. S); 291 (Abstract).
37. Hall JE, Brands MW, Shek EW. Central role of the kidney and abnormal fluid volume control in hypertension. J. Hum. Hypertens. 1996; 10: 633-639 (Pubitemid 27037509)
38. Burke SL, Head GA, Lambert GW, Evans RG. Renal sympathetic neuroeffector function in renovascular and angiotensin II-dependent hypertension in rabbits. Hypertension 2007; 49: 932-938
39. Wright CE, Angus JA. Enhanced total peripheral, vascular responsiveness in hypertension accords with the amplifier hypothesis. J. Hypertens. 1999;17:1687-1696
40. Unsel N, Benian A, Erel CT. Leptin levels in women, with hyperemesis gravidarum. Int. J. Gynaecol. Obstet. 2004; 84: 162-163 (Pubitemid 38210010)
41. Seckl JR, Holmes MC. Mechanisms of disease: Glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology. Nat. Clin. Pract. Endocrinol Metab. 2007; 3:479-488
42. Van den Bergh. BR, Van. Calster B, Smits T, Van Huffel S, Lagae L. Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: A prospective study on the fetal, origins of depressed mood. Neuropsychopharmacology 2008; 33: 536-545