Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 308, Issue 10, 2015, Pages L1046-L1057

  Helenius, Mikko H ^a   Vattulainen, Sanna ^a   Orcholski, Mark ^b   Aho, Joonas ^c   Komulainen, Anne ^a   Taimen, Pekka ^d   Wang, Lingli ^b   De Jesus Perez, Vinicio A ^b   Koskenvuo, Juha W ^c,e   Alastalo, Tero Pekka ^a  

^a UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF TURKU   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Apelin; ATP; NTPDaseI CD39; Pulmonary arterial hypertension; Vascular remodeling

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; APELIN; CD39 ANTIGEN; MESSENGER RNA; PURINERGIC P2Y11 RECEPTOR; APLN PROTEIN, HUMAN; APYRASE; LEUKOCYTE ANTIGEN; P2RY11 PROTEIN, HUMAN; PURINERGIC P2 RECEPTOR; SIGNAL PEPTIDE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; PULMONARY VASCULAR DISEASE; RAT; VASCULAR SMOOTH MUSCLE CELL; BIOSYNTHESIS; CELL LINE; CLINICAL TRIAL; ENZYMOLOGY; GENE EXPRESSION REGULATION; METABOLISM; MIDDLE AGED; MULTICENTER STUDY; PATHOLOGY; PULMONARY ARTERY; VASCULAR REMODELING;

ADENOSINE TRIPHOSPHATE; ADULT; ANTIGENS, CD; APYRASE; CELL LINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPERTENSION, PULMONARY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; PULMONARY ARTERY; RECEPTORS, PURINERGIC P2; VASCULAR REMODELING;

EID: 84930841688     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00340.2014     Document Type: Article

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