Inducible deletion of protein kinase Map4k4 in obese mice improves insulin sensitivity in liver and adipose tissues

Molecular and Cellular Biology

Volumn 35, Issue 13, 2015, Pages 2356-2365

  Danai, Laura V ^a   Roth Flach, Rachel J ^a   Virbasius, Joseph V ^a   Menendez, Lorena Garcia ^a,b   Jung, Dae Young ^a   Kim, Jong Hun ^a   Kim, Jason K ^a   Czech, Michael P ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALBUMIN; CRE RECOMBINASE; FATTY ACID; FIBROBLAST GROWTH FACTOR 21; GLUCOSE; INSULIN; INTERLEUKIN 6; IRISIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4; MYOGENIC FACTOR 5; PROTEIN KINASE B; TAMOXIFEN; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; MYF5 PROTEIN, MOUSE; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE;

ADIPOSE TISSUE; ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; BETA3 ADRENERGIC STIMULATION; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; ENERGY EXPENDITURE; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FAT MASS; FATTY ACID BLOOD LEVEL; FOOD INTAKE; GENE DELETION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIVER; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PHENOTYPE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; ANALYSIS; ANIMAL; BLOOD; C57BL MOUSE; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE MUTANT;

ANIMALIA; MUS;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; GENE DELETION; GLUCOSE; INSULIN; INSULIN RESISTANCE; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; MYOGENIC REGULATORY FACTOR 5; OBESITY; PROTEIN-SERINE-THREONINE KINASES; TAMOXIFEN;

EID: 84930830928     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00150-15     Document Type: Article

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