The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin

Biomaterials

Volumn 62, Issue , 2015, Pages 176-187

  Lu, Jianqin ^a,b,d   Liu, Chuang ^c   Wang, Pengcheng ^a,b   Ghazwani, Mohammed ^a,b   Xu, Jieni ^a,b   Huang, Yixian ^a,b   Ma, Xiaochao ^a,b   Zhang, Peijun ^c   Li, Song ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Camptothecin; Chemotherapy; Disulfide responsive release; Nanofibers; Tocopherol based prodrug

Indexed keywords

CHEMOTHERAPY; ESTERS; HISTOLOGY; HYDROGEN BONDS; HYDROPHOBICITY; MICELLES; QUENCHING; SULFUR COMPOUNDS; TUMORS;

BREAST CANCER MODELS; CAMPTOTHECIN (CPT); CLINICAL APPLICATION; DISULFIDE-RESPONSIVE RELEASE; EFFECTIVE APPROACHES; HYDROPHOBIC INTERACTIONS; PRODRUGS; SELF ASSEMBLY PROCESS;

NANOFIBERS;

ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CARBONIC ACID; NANOCAPSULE; PRODRUG; TOCOPHEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; FEMALE; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HYDROGEN BOND; HYDROPHOBICITY; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; TUMOR CELL; ANIMAL; BREAST NEOPLASMS; CELL SURVIVAL; CHEMISTRY; DIFFUSION; DRUG EFFECTS; DRUG POTENTIATION; PARTICLE SIZE; PATHOLOGY; PROCEDURES; TREATMENT OUTCOME; TUMOR CELL LINE; ULTRASTRUCTURE;

MURINAE;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CAMPTOTHECIN; CELL LINE, TUMOR; CELL SURVIVAL; DIFFUSION; DRUG COMPOUNDING; DRUG STABILITY; DRUG SYNERGISM; MICE; NANOCAPSULES; PARTICLE SIZE; PRODRUGS; TOCOPHEROLS; TREATMENT OUTCOME;

EID: 84930793784     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.05.046     Document Type: Article

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