PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

Genes and Development

Volumn 29, Issue 11, 2015, Pages 1106-1119

  Iwayama, Tomoaki ^a   Steele, Cameron ^a   Yao, Longbiao ^a   Dozmorov, Mikhail G ^a,b   Karamichos, Dimitris ^c   Wren, Jonathan D ^a   Olson, Lorin E ^a,c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Adipogenesis; Fibrosis; Imprinting; Nestin; Pericyte; Platelet derived growth factor

Indexed keywords

COLLAGEN; COLLAGEN TYPE 3; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GENOMIC RNA; MAMMALIAN TARGET OF RAPAMYCIN; MYOSIN; NESTIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEOCHONDROITIN SULFATE; RIBOSOME PROTEIN; VASCULOTROPIN RECEPTOR 2;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ADIPOSE TISSUE FIBROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; CELL ACTIVATION; CELL GROWTH; CONTROLLED STUDY; EPIGENETICS; EX VIVO STUDY; EXTRACELLULAR MATRIX; FIBROSIS; GENE EXPRESSION; MOUSE; NONHUMAN; PERICYTE; PLASTICITY; PRIORITY JOURNAL; PROGENITOR CELL PLASTICITY; PROTEIN TARGETING; RIBOSOME; RNA TRANSLATION; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENE; UPREGULATION; VASCULAR SMOOTH MUSCLE CELL; WHITE ADIPOSE TISSUE; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

MUS;

ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CELLS, CULTURED; FIBROSIS; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84930790056     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.260554.115     Document Type: Article

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