Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice

Experimental Hematology

Volumn 43, Issue 7, 2015, Pages 565-577.e10

  Nandakumar, Satish K ^a   Johnson, Kyle ^a   Throm, Stacy L ^a   Pestina, Tamara I ^a   Neale, Geoffrey ^a   Persons, Derek A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; TAMOXIFEN; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR HOXA9; GATA2 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; HYBRID PROTEIN; SYNTHETIC DNA;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; BONE MARROW CULTURE; BONE MARROW TRANSPLANTATION; CELL ACTIVITY; CELL EXPANSION; CELL GROWTH; CELL IMMORTALIZATION; CELL LINEAGE; CELL NUCLEUS; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; GENE; GENE ACTIVATION; GRANULOCYTE; HOXA9 GENE; IMMORTALIZED CELL LINE; IN VITRO STUDY; LYMPHOCYTE DIFFERENTIATION; MONOCYTE; MOUSE; MYELOID LEUKEMIA; MYELOID PROGENITOR CELL; NMYC GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE; TRANSGENIC MOUSE; ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIVISION; CELL TRANSFORMATION; CFU COUNTING; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL; HUMAN; LYMPHOPOIESIS; METABOLISM; MUTATION; MYELOPOIESIS; ONCOGENE MYC; PATHOLOGY; PHYSIOLOGY;

MUS; MUS MUSCULUS;

ANIMALS; B-LYMPHOCYTES; BONE MARROW CELLS; CELL DIVISION; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, MYC; GENES, SYNTHETIC; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA, MYELOID, ACUTE; LYMPHOPOIESIS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; MYELOID CELLS; MYELOPOIESIS; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES; TAMOXIFEN;

EID: 84930789175     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2015.04.002     Document Type: Article

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