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Volumn 120, Issue 10, 2012, Pages 2064-2075

High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 2; WT1 PROTEIN;

EID: 84866141111     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-12-397083     Document Type: Article
Times cited : (63)

References (52)
  • 1
    • 79952078495 scopus 로고    scopus 로고
    • Biology, risk stratification, and therapy of pediatric acute leukemias: An update
    • Pui CH, Carroll WL, Meshinchi S, Arceci RJ. Biology, risk stratification, and therapy of pediatric acute leukemias: an update. J Clin Oncol. 2011;29(5):551-565.
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 551-565
    • Pui, C.H.1    Carroll, W.L.2    Meshinchi, S.3    Arceci, R.J.4
  • 2
    • 36349018880 scopus 로고    scopus 로고
    • Pediatric acute myeloid leukemia: Towards high-quality cure of all patients
    • Kaspers GJ, Zwaan CM. Pediatric acute myeloid leukemia: towards high-quality cure of all patients. Haematologica. 2007;92(11):1519-1532.
    • (2007) Haematologica , vol.92 , Issue.11 , pp. 1519-1532
    • Kaspers, G.J.1    Zwaan, C.M.2
  • 3
    • 79958864954 scopus 로고    scopus 로고
    • Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: A report from the Children's Oncology Group
    • Ho PA, Kutny MA, Alonzo TA, et al. Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2011;57(2):204-209.
    • (2011) Pediatr Blood Cancer , vol.57 , Issue.2 , pp. 204-209
    • Ho, P.A.1    Kutny, M.A.2    Alonzo, T.A.3
  • 4
    • 80053621525 scopus 로고    scopus 로고
    • Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia
    • Balgobind BV, Hollink IH, Arentsen-Peters ST, et al. Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia. Haematologica. 2011;96(10):1478-1487.
    • (2011) Haematologica , vol.96 , Issue.10 , pp. 1478-1487
    • Balgobind, B.V.1    Hollink, I.H.2    Arentsen-Peters, S.T.3
  • 5
    • 77956429361 scopus 로고    scopus 로고
    • Clinical significance of flow cytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol
    • van der Velden V, van der Sluijs-Geling Gibson BE, et al. Clinical significance of flow cytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol. Leukemia. 2010;24(9):1599-1606.
    • (2010) Leukemia , vol.24 , Issue.9 , pp. 1599-1606
    • Van Der Velden, V.1    Van Der Sluijs-Geling Gibson, B.E.2
  • 6
    • 77958468721 scopus 로고    scopus 로고
    • Assessment of minimal residual disease in acute myeloid leukemia
    • Grimwade D, Vyas P, Freeman S. Assessment of minimal residual disease in acute myeloid leukemia. Curr Opin Oncol. 2010;22(6):656-663.
    • (2010) Curr Opin Oncol , vol.22 , Issue.6 , pp. 656-663
    • Grimwade, D.1    Vyas, P.2    Freeman, S.3
  • 7
    • 0034890863 scopus 로고    scopus 로고
    • Hematologic malignancies
    • Gilliland DG. Hematologic malignancies. Curr Opin Hematol. 2001;8(4):189-191.
    • (2001) Curr Opin Hematol , vol.8 , Issue.4 , pp. 189-191
    • Gilliland, D.G.1
  • 8
    • 0028022916 scopus 로고
    • An early haematopoietic defect in mice lacking the transcription factor GATA-2
    • Tsai FY, Keller G, Kuo FC, et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature. 1994;371(6494):221-226.
    • (1994) Nature , vol.371 , Issue.6494 , pp. 221-226
    • Tsai, F.Y.1    Keller, G.2    Kuo, F.C.3
  • 9
    • 34848888910 scopus 로고    scopus 로고
    • Differential gene expression in human hematopoietic stem cells specified toward erythroid, megakaryocytic, and granulocytic lineage
    • Liu XL, Yuan JY, Zhang JW, Zhang XH, Wang RX. Differential gene expression in human hematopoietic stem cells specified toward erythroid, megakaryocytic, and granulocytic lineage. J Leukoc Biol. 2007;82(4):986-1002.
    • (2007) J Leukoc Biol , vol.82 , Issue.4 , pp. 986-1002
    • Liu, X.L.1    Yuan, J.Y.2    Zhang, J.W.3    Zhang, X.H.4    Wang, R.X.5
  • 11
    • 0028907850 scopus 로고
    • Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis
    • Labbaye C, Valtieri M, Barberi T, et al. Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis. J Clin Invest. 1995;95(5):2346-2358.
    • (1995) J Clin Invest , vol.95 , Issue.5 , pp. 2346-2358
    • Labbaye, C.1    Valtieri, M.2    Barberi, T.3
  • 12
    • 13544263218 scopus 로고    scopus 로고
    • The transcriptional program of terminal granulocytic differentiation
    • Theilgaard-Mönch K, Jacobsen LC, Borup R, et al. The transcriptional program of terminal granulocytic differentiation. Blood. 2005;105(4):1785-1796.
    • (2005) Blood , vol.105 , Issue.4 , pp. 1785-1796
    • Theilgaard-Mönch, K.1    Jacobsen, L.C.2    Borup, R.3
  • 13
    • 0027265437 scopus 로고
    • Dynamics of GATA transcription factor expression during erythroid differentiation
    • Leonard M, Brice M, Engel JD, Papayannopoulou T. Dynamics of GATA transcription factor expression during erythroid differentiation. Blood. 1993;82(4):1071-1079.
    • (1993) Blood , vol.82 , Issue.4 , pp. 1071-1079
    • Leonard, M.1    Brice, M.2    Engel, J.D.3    Papayannopoulou, T.4
  • 14
  • 15
    • 0033555811 scopus 로고    scopus 로고
    • Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis
    • Persons DA, Allay JA, Allay ER, et al. Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood. 1999;93(2):488-499.
    • (1999) Blood , vol.93 , Issue.2 , pp. 488-499
    • Persons, D.A.1    Allay, J.A.2    Allay, E.R.3
  • 16
    • 63849118537 scopus 로고    scopus 로고
    • High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle
    • Tipping AJ, Pina C, Castor A, et al. High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. Blood. 2009;113(12):2661-2672.
    • (2009) Blood , vol.113 , Issue.12 , pp. 2661-2672
    • Tipping, A.J.1    Pina, C.2    Castor, A.3
  • 17
    • 0037124323 scopus 로고    scopus 로고
    • GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors
    • Kitajima K, Masuhara M, Era T, Enver T, Nakano T. GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors. EMBO J. 2002;21(12):3060-3069.
    • (2002) EMBO J , vol.21 , Issue.12 , pp. 3060-3069
    • Kitajima, K.1    Masuhara, M.2    Era, T.3    Enver, T.4    Nakano, T.5
  • 18
    • 33344478730 scopus 로고    scopus 로고
    • Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2
    • Kitajima K, Tanaka M, Zheng J, et al. Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2. Blood. 2006;107(5):1857-1863.
    • (2006) Blood , vol.107 , Issue.5 , pp. 1857-1863
    • Kitajima, K.1    Tanaka, M.2    Zheng, J.3
  • 19
    • 0030926190 scopus 로고    scopus 로고
    • Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation
    • Tsai FY, Orkin SH. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood. 1997;89(10):3636-3643.
    • (1997) Blood , vol.89 , Issue.10 , pp. 3636-3643
    • Tsai, F.Y.1    Orkin, S.H.2
  • 20
    • 70349229824 scopus 로고    scopus 로고
    • Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate
    • Chou ST, Khandros E, Bailey LC, et al. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood. 2009;114(5):983-994.
    • (2009) Blood , vol.114 , Issue.5 , pp. 983-994
    • Chou, S.T.1    Khandros, E.2    Bailey, L.C.3
  • 21
    • 70249123849 scopus 로고    scopus 로고
    • GATA-2 reinforces megakaryocyte development in the absence of GATA-1
    • Huang Z, Dore LC, Li Z, et al. GATA-2 reinforces megakaryocyte development in the absence of GATA-1. Mol Cell Biol. 2009;29(18):5168-5180.
    • (2009) Mol Cell Biol , vol.29 , Issue.18 , pp. 5168-5180
    • Huang, Z.1    Dore, L.C.2    Li, Z.3
  • 22
    • 0027264128 scopus 로고
    • Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner
    • Briegel K, Lim KC, Plank C, Beug H, Engel JD, Zenke M. Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. Genes Dev. 1993;7(6):1097-1109.
    • (1993) Genes Dev , vol.7 , Issue.6 , pp. 1097-1109
    • Briegel, K.1    Lim, K.C.2    Plank, C.3    Beug, H.4    Engel, J.D.5    Zenke, M.6
  • 23
    • 0035760308 scopus 로고    scopus 로고
    • Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression
    • Kumano K, Chiba S, Shimizu K, et al. Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression. Blood. 2001;98(12):3283- 3289.
    • (2001) Blood , vol.98 , Issue.12 , pp. 3283-3289
    • Kumano, K.1    Chiba, S.2    Shimizu, K.3
  • 24
    • 33646008578 scopus 로고    scopus 로고
    • Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors
    • de Pooter RF, Schmitt TM, de la Pompa JL, Fujiwara Y, Orkin SH, Zuniga-Pflucker JC. Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors. J Immunol. 2006;176(9):5267-5275.
    • (2006) J Immunol , vol.176 , Issue.9 , pp. 5267-5275
    • De Pooter, R.F.1    Schmitt, T.M.2    De La Pompa, J.L.3    Fujiwara, Y.4    Orkin, S.H.5    Zuniga-Pflucker, J.C.6
  • 25
    • 0033587755 scopus 로고    scopus 로고
    • Negative crosstalk between hematopoietic regulators: GATA proteins repress PU. 1
    • Zhang P, Behre G, Pan J, et al. Negative crosstalk between hematopoietic regulators: GATA proteins repress PU. 1. Proc Natl Acad Sci U S A. 1999;96(15):8705-8710.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.15 , pp. 8705-8710
    • Zhang, P.1    Behre, G.2    Pan, J.3
  • 26
    • 79953176952 scopus 로고    scopus 로고
    • Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
    • Yan XJ, Xu J, Gu ZH, et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011;43(4):309-315.
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 309-315
    • Yan, X.J.1    Xu, J.2    Gu, Z.H.3
  • 27
    • 41149169150 scopus 로고    scopus 로고
    • Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia
    • Zhang SJ, Ma LY, Huang QH, et al. Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2008;105(6):2076-2081.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.6 , pp. 2076-2081
    • Zhang, S.J.1    Ma, L.Y.2    Huang, Q.H.3
  • 28
    • 67349119504 scopus 로고    scopus 로고
    • GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism
    • Zhang SJ, Shi JY, Li JY. GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism. Leuk Res. 2009;33(8):1141-1143.
    • (2009) Leuk Res , vol.33 , Issue.8 , pp. 1141-1143
    • Zhang, S.J.1    Shi, J.Y.2    Li, J.Y.3
  • 29
    • 80053383273 scopus 로고    scopus 로고
    • Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia
    • Hahn CN, Chong CE, Carmichael CL, et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nat Genet. 2011;43(10):1012-1017.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 1012-1017
    • Hahn, C.N.1    Chong, C.E.2    Carmichael, C.L.3
  • 30
    • 84863012056 scopus 로고    scopus 로고
    • Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature
    • Kazenwadel J, Secker GA, Liu YJ, et al. Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature. Blood. 2012;119(5):1283-1291.
    • (2012) Blood , vol.119 , Issue.5 , pp. 1283-1291
    • Kazenwadel, J.1    Secker, G.A.2    Liu, Y.J.3
  • 31
    • 84862129223 scopus 로고    scopus 로고
    • Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival
    • Bödör C, Renneville A, Smith M, et al. Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival. Haematologica. 2012;97(6):890-894.
    • (2012) Haematologica , vol.97 , Issue.6 , pp. 890-894
    • Bödör, C.1    Renneville, A.2    Smith, M.3
  • 32
    • 84863449106 scopus 로고    scopus 로고
    • Marked genetic heterogeneity in familial myelodysplasia/acute myeloid leukaemia
    • Holme H, Hossain U, Kirwan M, Walne A, Vulliamy T, Dokal I. Marked genetic heterogeneity in familial myelodysplasia/acute myeloid leukaemia. Br J Haematol. 2012;158(2):242-248.
    • (2012) Br J Haematol , vol.158 , Issue.2 , pp. 242-248
    • Holme, H.1    Hossain, U.2    Kirwan, M.3    Walne, A.4    Vulliamy, T.5    Dokal, I.6
  • 33
    • 79961074298 scopus 로고    scopus 로고
    • Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
    • Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood. 2011;118(10):2653-2655.
    • (2011) Blood , vol.118 , Issue.10 , pp. 2653-2655
    • Hsu, A.P.1    Sampaio, E.P.2    Khan, J.3
  • 34
    • 80052089944 scopus 로고    scopus 로고
    • Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency
    • Dickinson RE, Griffin H, Bigley V, et al. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood. 2011;118(10):2656-2658.
    • (2011) Blood , vol.118 , Issue.10 , pp. 2656-2658
    • Dickinson, R.E.1    Griffin, H.2    Bigley, V.3
  • 35
    • 80053385569 scopus 로고    scopus 로고
    • Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
    • Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat Genet. 2011;43(10):929-931.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 929-931
    • Ostergaard, P.1    Simpson, M.A.2    Connell, F.C.3
  • 36
    • 0028032922 scopus 로고
    • Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay
    • Kaspers GJ, Veerman AJ, Pieters R, et al. Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay. Br J Cancer. 1994;70(6):1047-1052.
    • (1994) Br J Cancer , vol.70 , Issue.6 , pp. 1047-1052
    • Kaspers, G.J.1    Veerman, A.J.2    Pieters, R.3
  • 37
    • 62249168182 scopus 로고    scopus 로고
    • Acute myeloid leukemia with recurrent genetic abnormalities
    • Swerdlow S, Campo E, Harris NL, eds. 4th Ed. Geneva, Switzerland: World Health Organization
    • Arber DA, Brunning RD, Le Beau MM, et al. Acute myeloid leukemia with recurrent genetic abnormalities. In: Swerdlow S, Campo E, Harris NL, eds. WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. 4th Ed. Geneva, Switzerland: World Health Organization; 2008:110-123.
    • (2008) WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues , pp. 110-123
    • Arber, D.A.1    Brunning, R.D.2    Le Beau, M.M.3
  • 38
    • 78650310697 scopus 로고    scopus 로고
    • High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome
    • Balgobind BV, Zwaan CM, Reinhardt D, et al. High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome. Leukemia. 2010;24(12):2048-2055.
    • (2010) Leukemia , vol.24 , Issue.12 , pp. 2048-2055
    • Balgobind, B.V.1    Zwaan, C.M.2    Reinhardt, D.3
  • 39
    • 77953288751 scopus 로고    scopus 로고
    • Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique
    • Balgobind BV, Hollink IH, Reinhardt D, et al. Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique. Eur J Cancer. 2010;46(10):1892-1899.
    • (2010) Eur J Cancer , vol.46 , Issue.10 , pp. 1892-1899
    • Balgobind, B.V.1    Hollink, I.H.2    Reinhardt, D.3
  • 40
    • 77952426083 scopus 로고    scopus 로고
    • EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia
    • Balgobind BV, Lugthart S, Hollink IH, et al. EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia. Leukemia. 2010;24(5):942-949.
    • (2010) Leukemia , vol.24 , Issue.5 , pp. 942-949
    • Balgobind, B.V.1    Lugthart, S.2    Hollink, I.H.3
  • 41
    • 79551628927 scopus 로고    scopus 로고
    • Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia
    • Balgobind BV, van den Heuvel-Eibrink MM, De Menezes RX, et al. Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia. Haematologica. 2011;96(2):221-230.
    • (2011) Haematologica , vol.96 , Issue.2 , pp. 221-230
    • Balgobind, B.V.1    Van Den Heuvel-Eibrink, M.M.2    De Menezes, R.X.3
  • 42
    • 78049436798 scopus 로고    scopus 로고
    • No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia
    • Hollink IH, van den Heuvel-Eibrink MM, Zimmermann M, et al. No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia. J Clin Oncol. 2010;28(28):e523-e526.
    • (2010) J Clin Oncol , vol.28 , Issue.28
    • Hollink, I.H.1    Van Den Heuvel-Eibrink, M.M.2    Zimmermann, M.3
  • 43
    • 0036046115 scopus 로고    scopus 로고
    • Abnormal WT1 expression in the CD34-negative compartment in myelodysplastic bone marrow
    • Van Dijk JP, Knops GH, Van De Locht LT, et al. Abnormal WT1 expression in the CD34-negative compartment in myelodysplastic bone marrow. Br J Haematol. 2002;118(4):1027-1033.
    • (2002) Br J Haematol , vol.118 , Issue.4 , pp. 1027-1033
    • Van Dijk, J.P.1    Knops, G.H.2    Van De Locht, L.T.3
  • 44
    • 70449726860 scopus 로고    scopus 로고
    • Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: A European LeukemiaNet study
    • Cilloni D, Renneville A, Hermitte F, et al. Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: a European LeukemiaNet study. J Clin Oncol. 2009;27(31):5195-5201.
    • (2009) J Clin Oncol , vol.27 , Issue.31 , pp. 5195-5201
    • Cilloni, D.1    Renneville, A.2    Hermitte, F.3
  • 45
    • 79952323651 scopus 로고    scopus 로고
    • Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia
    • Hollink IH, van den Heuvel-Eibrink MM, Arentsen-Peters ST, et al. Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia. Haematologica. 2011;96(3):384-392.
    • (2011) Haematologica , vol.96 , Issue.3 , pp. 384-392
    • Hollink, I.H.1    Van Den Heuvel-Eibrink, M.M.2    Arentsen-Peters, S.T.3
  • 46
    • 79151472081 scopus 로고    scopus 로고
    • Wilms' tumours: About tumour suppressor genes, an oncogene and a chameleon gene
    • Huff V. Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene. Nat Rev Cancer. 2011;11(2):111-121.
    • (2011) Nat Rev Cancer , vol.11 , Issue.2 , pp. 111-121
    • Huff, V.1
  • 47
    • 33645746149 scopus 로고    scopus 로고
    • High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia
    • Lapillonne H, Renneville A, Auvrignon A, et al. High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia. J Clin Oncol. 2006;24(10):1507-1515.
    • (2006) J Clin Oncol , vol.24 , Issue.10 , pp. 1507-1515
    • Lapillonne, H.1    Renneville, A.2    Auvrignon, A.3
  • 48
    • 34547658148 scopus 로고    scopus 로고
    • Feasibility of using the combined MDS-EVI1/EVI1 gene expression as an alternative molecular marker in acute myeloid leukemia: A report of four cases
    • Weisser M, Haferlach C, Haferlach T, Schnittger S. Feasibility of using the combined MDS-EVI1/EVI1 gene expression as an alternative molecular marker in acute myeloid leukemia: a report of four cases. Cancer Genet Cytogenet. 2007;177(1):64-69.
    • (2007) Cancer Genet Cytogenet , vol.177 , Issue.1 , pp. 64-69
    • Weisser, M.1    Haferlach, C.2    Haferlach, T.3    Schnittger, S.4
  • 49
    • 59949090392 scopus 로고    scopus 로고
    • Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia
    • Ayala RM, Martinez-Lopez J, Albizua E, Diez A, Gilsanz F. Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia. Am J Hematol. 2009;84(2):79-86.
    • (2009) Am J Hematol , vol.84 , Issue.2 , pp. 79-86
    • Ayala, R.M.1    Martinez-Lopez, J.2    Albizua, E.3    Diez, A.4    Gilsanz, F.5
  • 50
    • 0028856588 scopus 로고
    • The expression pattern of erythrocyte/megakaryocyte-related transcription factors GATA-1 and the stem cell leukemia gene correlates with hematopoietic differentiation and is associated with outcome of acute myeloid leukemia
    • Shimamoto T, Ohyashiki K, Ohyashiki JH, et al. The expression pattern of erythrocyte/megakaryocyte-related transcription factors GATA-1 and the stem cell leukemia gene correlates with hematopoietic differentiation and is associated with outcome of acute myeloid leukemia. Blood. 1995;86(8):3173-3180.
    • (1995) Blood , vol.86 , Issue.8 , pp. 3173-3180
    • Shimamoto, T.1    Ohyashiki, K.2    Ohyashiki, J.H.3
  • 51
    • 84857997066 scopus 로고    scopus 로고
    • Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities
    • Vicente C, Vazquez I, Conchillo A, et al. Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities. Leukemia. 2012;26(3):550-554.
    • (2012) Leukemia , vol.26 , Issue.3 , pp. 550-554
    • Vicente, C.1    Vazquez, I.2    Conchillo, A.3
  • 52
    • 16544369516 scopus 로고    scopus 로고
    • Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia
    • Bullinger L, Dohner K, Bair E, et al. Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med. 2004;350(16):1605-1616.
    • (2004) N Engl J Med , vol.350 , Issue.16 , pp. 1605-1616
    • Bullinger, L.1    Dohner, K.2    Bair, E.3


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