A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Bhatt, Dhaval P ^a,b   Puig, Kendra L ^a   Gorr, Matthew W ^c,d   Wold, Loren E ^c,d   Combs, Colin K ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BINDING PROTEIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN IBA 1; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ASPARTIC PROTEINASE; AUTACOID; BACE1 PROTEIN, MOUSE; BIOLOGICAL MARKER; DLGH4 PROTEIN, MOUSE; GUANYLATE KINASE; MEMBRANE PROTEIN; PARTICULATE MATTER; PROSTAGLANDIN SYNTHASE; SECRETASE; TAU PROTEIN;

AIR POLLUTANT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; ENCEPHALITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; INHALATION; LONG TERM EXPOSURE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PARTICULATE MATTER; PILOT STUDY; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; BRAIN; C57BL MOUSE; DNA METHYLATION; EXPOSURE; GLIA; MALE; METABOLISM; NITROSATION; OXIDATIVE STRESS; PATHOLOGY; PHOSPHORYLATION;

CANIS FAMILIARIS; MUS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BIOMARKERS; BRAIN; CYTOKINES; DNA METHYLATION; GLIAL FIBRILLARY ACIDIC PROTEIN; GUANYLATE KINASES; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; NEUROGLIA; NITROSATION; OXIDATIVE STRESS; PARTICULATE MATTER; PHOSPHORYLATION; PILOT PROJECTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; TAU PROTEINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84930673168     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127102     Document Type: Article

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