Detection of innate immune response modulating impurities in therapeutic proteins

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Haile, Lydia Asrat ^a   Puig, Montserrat ^a   Kelley Baker, Logan ^a   Verthelyi, Daniela ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR; CHEMOKINE; CYTOKINE; PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOMODULATION; INNATE IMMUNE RESPONSE MODULATING IMPURITY; INNATE IMMUNITY; LIMIT OF DETECTION; LOWER LIMIT OF DETECTION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; ANIMAL; ANTIGEN PRESENTING CELL; CELL LINE; IMMUNOLOGY; MONONUCLEAR CELL;

ANIMALS; ANTIGEN-PRESENTING CELLS; CELL LINE; CHEMOKINES; CYTOKINES; HUMANS; IMMUNITY, INNATE; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MICE; PROTEINS; TOLL-LIKE RECEPTORS;

EID: 84930668244     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125078     Document Type: Article

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