Galactosylated poly(Ethyleneglycol)-lithocholic acid selectively kills hepatoma cells, while sparing normal liver cells

Macromolecular Bioscience

Volumn 15, Issue 6, 2015, Pages 777-787

  Gankhuyag, Nomundelger ^a   Singh, Bijay ^a   Maharjan, Sushila ^a   Choi, Yun Jaie ^a   Cho, Chong Su ^a   Cho, Myung Haing ^a  

^a Seoul National University   (South Korea)

Author keywords

anti cancer drugs; apoptosis; hepatocyte specific; lithocholic acid; nanoparticles

Indexed keywords

CELL DEATH; CYTOLOGY; DISEASES; DRUG THERAPY; LIFE CYCLE; NANOPARTICLES; POLYOLS;

ANTICANCER DRUG; GALACTOSE LIGANDS; HEPATOCYTES; HEPATOMA CELLS; HIGH SPECIFICITY; LACTOBIONIC ACID; LITHOCHOLIC ACIDS; NANOPARTICLE FORMULATION;

CELLS;

ANTINEOPLASTIC AGENT; GALACTOSE; LACTOBIONIC ACID; LITHOCHOLIC ACID; MACROGOL; MACROGOL DERIVATIVE; POLYETHYLENE GLYCOL 1000;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; MOUSE; NONHUMAN; WESTERN BLOTTING; ANIMAL; CARCINOMA, HEPATOCELLULAR; CHEMISTRY; HEPG2 CELL LINE; LIVER; LIVER NEOPLASMS; METABOLISM; PROCEDURES;

ANIMALS; CARCINOMA, HEPATOCELLULAR; DRUG DELIVERY SYSTEMS; HEP G2 CELLS; HEPATOCYTES; HUMANS; LITHOCHOLIC ACID; LIVER; LIVER NEOPLASMS; MICE; POLYETHYLENE GLYCOLS;

EID: 84930667223     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201400475     Document Type: Article

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