Nickel may contribute to EGFR mutation and synergistically promotes tumor invasion in EGFR-mutated lung cancer via nickel-induced microRNA-21 expression

Toxicology Letters

Volumn 237, Issue 1, 2015, Pages 46-54

  Chiou, Yu Hu ^a   Liou, Saou Hsing ^b   Wong, Ruey Hong ^a   Chen, Chih Yi ^a   Lee, Huei ^c  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

EGFR mutation; MiR 21; Nickel; NSCLC; RECK

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 21; NICKEL; REVERSION INDUCING CYSTEINE RICH PROTEIN; SPROUTY PROTEIN; SPROUTY2 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; MEMBRANE PROTEIN; MICRORNA; MIRN21 MICRORNA, HUMAN; RECK PROTEIN, HUMAN; SIGNAL PEPTIDE; SPRY2 PROTEIN, HUMAN;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; LUNG CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; MALE; NON SMALL CELL LUNG CANCER; OVERALL SURVIVAL; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENCE FREE SURVIVAL; SEX DIFFERENCE; SIGNAL TRANSDUCTION; TUMOR INVASION; DNA REPAIR; DNA SEQUENCE; DRUG EFFECTS; GENETICS; KAPLAN MEIER METHOD; LUNG; LUNG NEOPLASMS; METABOLISM; MIDDLE AGED; PATHOLOGY; SMOKING; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CELL LINE, TUMOR; DNA REPAIR; FEMALE; GPI-LINKED PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KAPLAN-MEIER ESTIMATE; LUNG; LUNG NEOPLASMS; MALE; MEMBRANE PROTEINS; MICRORNAS; MIDDLE AGED; NF-KAPPA B; NICKEL; RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; SMOKING;

EID: 84930641697     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.05.019     Document Type: Article

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