Replication in bioanalytical studies with HDX MS: Aim as high as possible

Bioanalysis

Volumn 7, Issue 9, 2015, Pages 1065-1067

  Moroco, Jamie A ^a   Engen, John R ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

biopharmaceutical; comparability; error; hydrogen exchange; MS; reproducibility

Indexed keywords

BIOSIMILAR AGENT; CHOLESTEROL; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HIGH DENSITY LIPOPROTEIN; K RAS PROTEIN; LIPOSOME; MEMBRANE PROTEIN; NANODISC; RAS PROTEIN;

BLOOD SAMPLING; DEUTERIUM HYDROGEN EXCHANGE; DEUTERIUM HYDROGEN EXCHANGE MASS SPECTROMETRY; DRUG INDUSTRY; HUMAN; MASS SPECTROMETRY; MOLECULAR DYNAMICS; PROCESS MONITORING; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN PURIFICATION; REPLICATION STUDY; REPRODUCIBILITY; REVIEW; VALIDATION PROCESS; CHEMISTRY; CONFIDENCE INTERVAL; PROCEDURES;

CONFIDENCE INTERVALS; DEUTERIUM EXCHANGE MEASUREMENT; MASS SPECTROMETRY; MEMBRANE PROTEINS; RAS PROTEINS; REPRODUCIBILITY OF RESULTS;

EID: 84930589015     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.15.46     Document Type: Review

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