메뉴 건너뛰기




Volumn 14, Issue 6, 2015, Pages 2480-2491

Proteomic profiling of paclitaxel treated cells identifies a novel mechanism of drug resistance mediated by PDCD4

Author keywords

cell cycle; drug sensitivity; lung cancer; paclitaxel; PDCD4; personalized chemotherapy; quantitative proteomics; UBE2S

Indexed keywords

CELL PROTEIN; MESSENGER RNA; PACLITAXEL; PDCD4 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBE2S PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; PDCD4 PROTEIN, HUMAN; PROTEIN BINDING; RNA BINDING PROTEIN;

EID: 84930586812     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00004     Document Type: Article
Times cited : (24)

References (50)
  • 1
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Schiff, P. B.; Fant, J.; Horwitz, S. B. Promotion of microtubule assembly in vitro by taxol Nature 1979, 277 (5698) 665-7
    • (1979) Nature , vol.277 , Issue.5698 , pp. 665-667
    • Schiff, P.B.1    Fant, J.2    Horwitz, S.B.3
  • 2
    • 0030020158 scopus 로고    scopus 로고
    • Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
    • Jordan, M. A.; Wendell, K.; Gardiner, S.; Derry, W. B.; Copp, H.; Wilson, L. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death Cancer Res. 1996, 56 (4) 816-25
    • (1996) Cancer Res. , vol.56 , Issue.4 , pp. 816-825
    • Jordan, M.A.1    Wendell, K.2    Gardiner, S.3    Derry, W.B.4    Copp, H.5    Wilson, L.6
  • 3
    • 69549120405 scopus 로고    scopus 로고
    • How do anti-mitotic drugs kill cancer cells?
    • Gascoigne, K. E.; Taylor, S. S. How do anti-mitotic drugs kill cancer cells? J. Cell Sci. 2009, 122 (Pt 15) 2579-85
    • (2009) J. Cell Sci. , vol.122 , Issue.PART 15 , pp. 2579-2585
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 4
    • 7744233719 scopus 로고    scopus 로고
    • Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
    • Rieder, C. L.; Maiato, H. Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint Dev Cell 2004, 7 (5) 637-51
    • (2004) Dev Cell , vol.7 , Issue.5 , pp. 637-651
    • Rieder, C.L.1    Maiato, H.2
  • 6
    • 0030758777 scopus 로고    scopus 로고
    • Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization
    • Giannakakou, P.; Sackett, D. L.; Kang, Y. K.; Zhan, Z.; Buters, J. T.; Fojo, T.; Poruchynsky, M. S. Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization J. Biol. Chem. 1997, 272 (27) 17118-25
    • (1997) J. Biol. Chem. , vol.272 , Issue.27 , pp. 17118-17125
    • Giannakakou, P.1    Sackett, D.L.2    Kang, Y.K.3    Zhan, Z.4    Buters, J.T.5    Fojo, T.6    Poruchynsky, M.S.7
  • 7
    • 84890180718 scopus 로고    scopus 로고
    • Paclitaxel resistance by random mutagenesis of alpha-tubulin
    • Yin, S.; Zeng, C.; Hari, M.; Cabral, F. Paclitaxel resistance by random mutagenesis of alpha-tubulin Cytoskeleton 2013, 70 (12) 849-62
    • (2013) Cytoskeleton , vol.70 , Issue.12 , pp. 849-862
    • Yin, S.1    Zeng, C.2    Hari, M.3    Cabral, F.4
  • 8
    • 84895068588 scopus 로고    scopus 로고
    • Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines
    • Januchowski, R.; Wojtowicz, K.; Andrzejewska, M.; Zabel, M. Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines Biomed. Pharmacother. 2013, 68 (1) 111-7
    • (2013) Biomed. Pharmacother. , vol.68 , Issue.1 , pp. 111-117
    • Januchowski, R.1    Wojtowicz, K.2    Andrzejewska, M.3    Zabel, M.4
  • 9
    • 44449148739 scopus 로고    scopus 로고
    • Potential mechanisms of resistance to microtubule inhibitors
    • Kavallaris, M.; Annereau, J. P.; Barret, J. M. Potential mechanisms of resistance to microtubule inhibitors Semin. Oncol. 2008, 35 (3 Suppl 3) S22-7
    • (2008) Semin. Oncol. , vol.35 , Issue.3 , pp. 22-27
    • Kavallaris, M.1    Annereau, J.P.2    Barret, J.M.3
  • 10
    • 53149138610 scopus 로고    scopus 로고
    • Proteomic investigation of taxol and taxotere resistance and invasiveness in a squamous lung carcinoma cell line
    • Murphy, L.; Henry, M.; Meleady, P.; Clynes, M.; Keenan, J. Proteomic investigation of taxol and taxotere resistance and invasiveness in a squamous lung carcinoma cell line Biochim. Biophys. Acta 2008, 1784 (9) 1184-91
    • (2008) Biochim. Biophys. Acta , vol.1784 , Issue.9 , pp. 1184-1191
    • Murphy, L.1    Henry, M.2    Meleady, P.3    Clynes, M.4    Keenan, J.5
  • 11
    • 0029595270 scopus 로고
    • Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death
    • Shibahara, K.; Asano, M.; Ishida, Y.; Aoki, T.; Koike, T.; Honjo, T. Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death Gene 1995, 166 (2) 297-301
    • (1995) Gene , vol.166 , Issue.2 , pp. 297-301
    • Shibahara, K.1    Asano, M.2    Ishida, Y.3    Aoki, T.4    Koike, T.5    Honjo, T.6
  • 13
    • 22244491639 scopus 로고    scopus 로고
    • Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis
    • Jansen, A. P.; Camalier, C. E.; Colburn, N. H. Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis Cancer Res. 2005, 65 (14) 6034-41
    • (2005) Cancer Res. , vol.65 , Issue.14 , pp. 6034-6041
    • Jansen, A.P.1    Camalier, C.E.2    Colburn, N.H.3
  • 15
    • 35248889933 scopus 로고    scopus 로고
    • Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer
    • Mudduluru, G.; Medved, F.; Grobholz, R.; Jost, C.; Gruber, A.; Leupold, J. H.; Post, S.; Jansen, A.; Colburn, N. H.; Allgayer, H. Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer Cancer 2007, 110 (8) 1697-707
    • (2007) Cancer , vol.110 , Issue.8 , pp. 1697-1707
    • Mudduluru, G.1    Medved, F.2    Grobholz, R.3    Jost, C.4    Gruber, A.5    Leupold, J.H.6    Post, S.7    Jansen, A.8    Colburn, N.H.9    Allgayer, H.10
  • 16
    • 40449141403 scopus 로고    scopus 로고
    • Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both beta-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells
    • Wang, Q.; Sun, Z.; Yang, H. S. Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both beta-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells Oncogene 2008, 27 (11) 1527-35
    • (2008) Oncogene , vol.27 , Issue.11 , pp. 1527-1535
    • Wang, Q.1    Sun, Z.2    Yang, H.S.3
  • 17
    • 33749868662 scopus 로고    scopus 로고
    • Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma
    • Zhang, H.; Ozaki, I.; Mizuta, T.; Hamajima, H.; Yasutake, T.; Eguchi, Y.; Ideguchi, H.; Yamamoto, K.; Matsuhashi, S. Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma Oncogene 2006, 25 (45) 6101-12
    • (2006) Oncogene , vol.25 , Issue.45 , pp. 6101-6112
    • Zhang, H.1    Ozaki, I.2    Mizuta, T.3    Hamajima, H.4    Yasutake, T.5    Eguchi, Y.6    Ideguchi, H.7    Yamamoto, K.8    Matsuhashi, S.9
  • 18
    • 84862689246 scopus 로고    scopus 로고
    • DNA damage induces NF-kappaB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion
    • Niu, J.; Shi, Y.; Tan, G.; Yang, C. H.; Fan, M.; Pfeffer, L. M.; Wu, Z. H. DNA damage induces NF-kappaB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion J. Biol. Chem. 2012, 287 (26) 21783-95
    • (2012) J. Biol. Chem. , vol.287 , Issue.26 , pp. 21783-21795
    • Niu, J.1    Shi, Y.2    Tan, G.3    Yang, C.H.4    Fan, M.5    Pfeffer, L.M.6    Wu, Z.H.7
  • 19
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor PDCD4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani, I. A.; Rasheed, S. A.; Nikolova, D. A.; Leupold, J. H.; Colburn, N. H.; Post, S.; Allgayer, H. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor PDCD4 and stimulates invasion, intravasation and metastasis in colorectal cancer Oncogene 2008, 27 (15) 2128-36
    • (2008) Oncogene , vol.27 , Issue.15 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 20
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel, L. B.; Christoffersen, N. R.; Jacobsen, A.; Lindow, M.; Krogh, A.; Lund, A. H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells J. Biol. Chem. 2008, 283 (2) 1026-33
    • (2008) J. Biol. Chem. , vol.283 , Issue.2 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 21
    • 33750325725 scopus 로고    scopus 로고
    • S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
    • Dorrello, N. V.; Peschiaroli, A.; Guardavaccaro, D.; Colburn, N. H.; Sherman, N. E.; Pagano, M. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth Science 2006, 314 (5798) 467-71
    • (2006) Science , vol.314 , Issue.5798 , pp. 467-471
    • Dorrello, N.V.1    Peschiaroli, A.2    Guardavaccaro, D.3    Colburn, N.H.4    Sherman, N.E.5    Pagano, M.6
  • 22
    • 40449091284 scopus 로고    scopus 로고
    • Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion
    • Schmid, T.; Jansen, A. P.; Baker, A. R.; Hegamyer, G.; Hagan, J. P.; Colburn, N. H. Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion Cancer Res. 2008, 68 (5) 1254-60
    • (2008) Cancer Res. , vol.68 , Issue.5 , pp. 1254-1260
    • Schmid, T.1    Jansen, A.P.2    Baker, A.R.3    Hegamyer, G.4    Hagan, J.P.5    Colburn, N.H.6
  • 23
    • 4444285717 scopus 로고    scopus 로고
    • Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity
    • Jansen, A. P.; Camalier, C. E.; Stark, C.; Colburn, N. H. Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity Mol. Cancer Ther. 2004, 3 (2) 103-10
    • (2004) Mol. Cancer Ther. , vol.3 , Issue.2 , pp. 103-110
    • Jansen, A.P.1    Camalier, C.E.2    Stark, C.3    Colburn, N.H.4
  • 24
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong, S. E.; Blagoev, B.; Kratchmarova, I.; Kristensen, D. B.; Steen, H.; Pandey, A.; Mann, M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics Mol. Cell. Proteomics 2002, 1 (5) 376-86
    • (2002) Mol. Cell. Proteomics , vol.1 , Issue.5 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3    Kristensen, D.B.4    Steen, H.5    Pandey, A.6    Mann, M.7
  • 25
    • 0037317228 scopus 로고    scopus 로고
    • Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
    • Rappsilber, J.; Ishihama, Y.; Mann, M. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics Anal. Chem. 2003, 75 (3) 663-70
    • (2003) Anal. Chem. , vol.75 , Issue.3 , pp. 663-670
    • Rappsilber, J.1    Ishihama, Y.2    Mann, M.3
  • 26
    • 58149401890 scopus 로고    scopus 로고
    • The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses
    • Bakalarski, C. E.; Elias, J. E.; Villen, J.; Haas, W.; Gerber, S. A.; Everley, P. A.; Gygi, S. P. The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses J. Proteome Res. 2008, 7 (11) 4756-65
    • (2008) J. Proteome Res. , vol.7 , Issue.11 , pp. 4756-4765
    • Bakalarski, C.E.1    Elias, J.E.2    Villen, J.3    Haas, W.4    Gerber, S.A.5    Everley, P.A.6    Gygi, S.P.7
  • 27
    • 84891366081 scopus 로고    scopus 로고
    • Establishment of new intraperitoneal paclitaxel-resistant gastric cancer cell lines and comprehensive gene expression analysis
    • Murakami, H.; Ito, S.; Tanaka, H.; Kondo, E.; Kodera, Y.; Nakanishi, H. Establishment of new intraperitoneal paclitaxel-resistant gastric cancer cell lines and comprehensive gene expression analysis Anticancer Res. 2013, 33 (10) 4299-307
    • (2013) Anticancer Res. , vol.33 , Issue.10 , pp. 4299-4307
    • Murakami, H.1    Ito, S.2    Tanaka, H.3    Kondo, E.4    Kodera, Y.5    Nakanishi, H.6
  • 28
    • 84887989325 scopus 로고    scopus 로고
    • ICAM-3 endows anticancer drug resistance against microtubule-damaging agents via activation of the ICAM-3-AKT/ERK-CREB-2 pathway and blockage of apoptosis
    • Ahn, K. C.; Choi, J. Y.; Kim, J. S.; Hwang, S. G.; Kim, W. J.; Park, J. K.; Um, H. D. ICAM-3 endows anticancer drug resistance against microtubule-damaging agents via activation of the ICAM-3-AKT/ERK-CREB-2 pathway and blockage of apoptosis Biochem. Biophys. Res. Commun. 2013, 441 (2) 507-13
    • (2013) Biochem. Biophys. Res. Commun. , vol.441 , Issue.2 , pp. 507-513
    • Ahn, K.C.1    Choi, J.Y.2    Kim, J.S.3    Hwang, S.G.4    Kim, W.J.5    Park, J.K.6    Um, H.D.7
  • 29
    • 76549089605 scopus 로고    scopus 로고
    • UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex
    • Wu, T.; Merbl, Y.; Huo, Y.; Gallop, J. L.; Tzur, A.; Kirschner, M. W. UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex Proc. Natl. Acad. Sci. U.S.A. 2009, 107 (4) 1355-60
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , Issue.4 , pp. 1355-1360
    • Wu, T.1    Merbl, Y.2    Huo, Y.3    Gallop, J.L.4    Tzur, A.5    Kirschner, M.W.6
  • 30
    • 34547171850 scopus 로고    scopus 로고
    • The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition
    • Tedesco, D.; Zhang, J.; Trinh, L.; Lalehzadeh, G.; Meisner, R.; Yamaguchi, K. D.; Ruderman, D. L.; Dinter, H.; Zajchowski, D. A. The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition Neoplasia 2007, 9 (7) 601-13
    • (2007) Neoplasia , vol.9 , Issue.7 , pp. 601-613
    • Tedesco, D.1    Zhang, J.2    Trinh, L.3    Lalehzadeh, G.4    Meisner, R.5    Yamaguchi, K.D.6    Ruderman, D.L.7    Dinter, H.8    Zajchowski, D.A.9
  • 32
    • 84874620132 scopus 로고    scopus 로고
    • Quantitative proteomic analysis revealed N′-nitrosonornicotine-induced down-regulation of nonmuscle myosin II and reduced cell migration in cultured human skin fibroblast cells
    • Prins, J. M.; Wang, Y. Quantitative proteomic analysis revealed N′-nitrosonornicotine-induced down-regulation of nonmuscle myosin II and reduced cell migration in cultured human skin fibroblast cells J. Proteome Res. 2013, 12 (3) 1282-8
    • (2013) J. Proteome Res. , vol.12 , Issue.3 , pp. 1282-1288
    • Prins, J.M.1    Wang, Y.2
  • 34
    • 84874066193 scopus 로고    scopus 로고
    • Functional screen for secreted proteins by monoclonal antibody library and identification of Mac-2 Binding protein (Mac-2BP) as a potential therapeutic target and biomarker for lung cancer
    • Sun, L.; Chen, L.; Sun, L.; Pan, J.; Yu, L.; Han, L.; Yang, Z.; Luo, Y.; Ran, Y. Functional screen for secreted proteins by monoclonal antibody library and identification of Mac-2 Binding protein (Mac-2BP) as a potential therapeutic target and biomarker for lung cancer Mol. Cell. Proteomics 2013, 12 (2) 395-406
    • (2013) Mol. Cell. Proteomics , vol.12 , Issue.2 , pp. 395-406
    • Sun, L.1    Chen, L.2    Sun, L.3    Pan, J.4    Yu, L.5    Han, L.6    Yang, Z.7    Luo, Y.8    Ran, Y.9
  • 36
    • 84890713407 scopus 로고    scopus 로고
    • 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells
    • Zhang, F.; Fu, L.; Wang, Y. 6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells Mol. Cell. Proteomics 2013, 12 (12) 3803-11
    • (2013) Mol. Cell. Proteomics , vol.12 , Issue.12 , pp. 3803-3811
    • Zhang, F.1    Fu, L.2    Wang, Y.3
  • 37
    • 84873280967 scopus 로고    scopus 로고
    • Isocorydine targets the drug-resistant cellular side population through PDCD4-related apoptosis in hepatocellular carcinoma
    • Lu, P.; Sun, H.; Zhang, L.; Hou, H.; Zhang, L.; Zhao, F.; Ge, C.; Yao, M.; Wang, T.; Li, J. Isocorydine targets the drug-resistant cellular side population through PDCD4-related apoptosis in hepatocellular carcinoma Mol. Med. 2012, 18, 1136-46
    • (2012) Mol. Med. , vol.18 , pp. 1136-1146
    • Lu, P.1    Sun, H.2    Zhang, L.3    Hou, H.4    Zhang, L.5    Zhao, F.6    Ge, C.7    Yao, M.8    Wang, T.9    Li, J.10
  • 39
    • 84866285461 scopus 로고    scopus 로고
    • Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type i IFN responses
    • Kroczynska, B.; Sharma, B.; Eklund, E. A.; Fish, E. N.; Platanias, L. C. Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type I IFN responses Mol. Cell. Biol. 2012, 32 (14) 2809-22
    • (2012) Mol. Cell. Biol. , vol.32 , Issue.14 , pp. 2809-2822
    • Kroczynska, B.1    Sharma, B.2    Eklund, E.A.3    Fish, E.N.4    Platanias, L.C.5
  • 41
    • 84896393375 scopus 로고    scopus 로고
    • Significance of MicroRNAs in determining taxane resistance in ovarian cancer
    • Sultan, A.; K, T.; Chan, J.; Wang, Y.; Duran, G.; Francisco, B.; Sikic, B. Significance of MicroRNAs in determining taxane resistance in ovarian cancer Gynecol. Oncol. 2012, 125 (Suppl 1) S131
    • (2012) Gynecol. Oncol. , vol.125 , pp. 131
    • Sultan, A.1    Chan, J.2    Wang, Y.3    Duran, G.4    Francisco, B.5    Sikic, B.6
  • 44
    • 77349125856 scopus 로고    scopus 로고
    • MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol
    • Ren, Y.; Zhou, X.; Mei, M.; Yuan, X. B.; Han, L.; Wang, G. X.; Jia, Z. F.; Xu, P.; Pu, P. Y.; Kang, C. S. MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol BMC Cancer 2010, 10, 27
    • (2010) BMC Cancer , vol.10 , pp. 27
    • Ren, Y.1    Zhou, X.2    Mei, M.3    Yuan, X.B.4    Han, L.5    Wang, G.X.6    Jia, Z.F.7    Xu, P.8    Pu, P.Y.9    Kang, C.S.10
  • 45
    • 83355169699 scopus 로고    scopus 로고
    • Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA
    • Wedeken, L.; Singh, P.; Klempnauer, K. H. Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA J. Biol. Chem. 2011, 286 (50) 42855-62
    • (2011) J. Biol. Chem. , vol.286 , Issue.50 , pp. 42855-42862
    • Wedeken, L.1    Singh, P.2    Klempnauer, K.H.3
  • 46
    • 82955203485 scopus 로고    scopus 로고
    • PDCD4 directly binds the coding region of c-myb mRNA and suppresses its translation
    • Singh, P.; Wedeken, L.; Waters, L. C.; Carr, M. D.; Klempnauer, K. H. PDCD4 directly binds the coding region of c-myb mRNA and suppresses its translation Oncogene 2011, 30 (49) 4864-73
    • (2011) Oncogene , vol.30 , Issue.49 , pp. 4864-4873
    • Singh, P.1    Wedeken, L.2    Waters, L.C.3    Carr, M.D.4    Klempnauer, K.H.5
  • 47
    • 84861368165 scopus 로고    scopus 로고
    • Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2
    • Liwak, U.; Thakor, N.; Jordan, L. E.; Roy, R.; Lewis, S. M.; Pardo, O. E.; Seckl, M.; Holcik, M. Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2 Mol. Cell. Biol. 2012, 32 (10) 1818-29
    • (2012) Mol. Cell. Biol. , vol.32 , Issue.10 , pp. 1818-1829
    • Liwak, U.1    Thakor, N.2    Jordan, L.E.3    Roy, R.4    Lewis, S.M.5    Pardo, O.E.6    Seckl, M.7    Holcik, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.