Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis

Cancer Cell

Volumn 27, Issue 6, 2015, Pages 822-836

  Si, Wenzhe ^a   Huang, Wei ^b   Zheng, Yu ^b   Yang, Yang ^b   Liu, Xujun ^a   Shan, Lin ^b   Zhou, Xing ^b   Wang, Yue ^b   Su, Dongxue ^b   Gao, Jie ^b   Yan, Ruorong ^a   Han, Xiao ^a   Li, Wanjin ^a   He, Lin ^a   Shi, Lei ^b   Xuan, Chenghao ^b   Liang, Jing ^a   Sun, Luyang ^a   Wang, Yan ^b   Shang, Yongfeng ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; GLUTATHIONE TRANSFERASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; MYC PROTEIN; NERVE CELL ADHESION MOLECULE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR ZEB2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; WNT PROTEIN; GATA3 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; REPRESSOR PROTEIN; ZEB2 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST CARCINOGENESIS; BREAST METASTASIS; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL SURVIVAL; COHORT ANALYSIS; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEEDBACK SYSTEM; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; BREAST TUMOR; GENETIC TRANSFECTION; GENETICS; MCF 7 CELL LINE; METABOLISM; METASTASIS; NUDE MOUSE; PATHOLOGY; SCID MOUSE; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GATA3 TRANSCRIPTION FACTOR; HETEROGRAFTS; HOMEODOMAIN PROTEINS; HUMANS; MCF-7 CELLS; MICE; MICE, NUDE; MICE, SCID; NEOPLASM METASTASIS; REPRESSOR PROTEINS; TRANSFECTION;

EID: 84930576402     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2015.04.011     Document Type: Article

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