Eudragit S100 coated citrus pectin nanoparticles for colon targeting of 5-fluorouracil

Materials

Volumn 8, Issue 3, 2015, Pages 832-849

  Subudhi, M Biswaranjan ^a   Jain, Ankit ^a   Jain, Ashish ^a   Hurkat, Pooja ^a   Shilpi, Satish ^a   Gulbake, Arvind ^a   Jain, Sanjay K ^a  

^a DR H S GOUR UNIVERSITY   (India)

Author keywords

5 Fluorouracil; Cancer; Citrus pectin; Colon targeting; Eudragit S100

Indexed keywords

CELLS; CHEMOTHERAPY; DISEASES; PARTICLE SIZE;

5-FLUOROURACIL; CANCER; CITRUS PECTIN; COLON TARGETING; EUDRAGIT;

NANOPARTICLES;

EID: 84930506387     PISSN: None     EISSN: 19961944     Source Type: Journal    
DOI: 10.3390/ma8030832     Document Type: Article

References (51)

1. Chaurasia, M.; Chourasia, M.K.; Jain, N.K.; Jain, A.; Soni, V.; Gupta, Y.; Jain, S.K. Cross-linked guar gum microspheres: A viable approach for improved delivery of anticancer drugs for the treatment of colorectal cancer. AAPS PharmSciTech 2006, 7, E143-E151.
2. Dangi, R.; Hurkat, P.; Jain, A.; Shilpi, S.; Jain, A.; Gulbake, A.; Jain, S.K. Targeting liver cancer via ASGP receptor using 5-FU-loaded surface-modified PLGA nanoparticles. J. Microencapsul. 2014, 31, 479-487.
3. Hu, Y.; Jiang, X.; Ding, Y.; Ge, H.; Yuan, Y.; Yang, C. Synthesis and characterization of chitosan-poly (acrylic acid) nanoparticles. Biomaterials 2002, 23, 3193-3201.
4. Dou, H.; Jiang, M.; Peng, H.; Chen, D.; Hong, Y. Ph-dependent self-assembly: Micellization and micelle-hollow-sphere transition of cellulose-based copolymers. Angew. Chem. Int. Ed. 2003, 42, 1516-1519.
5. Tang, M.; Dou, H.; Sun, K. One-step synthesis of dextran-based stable nanoparticles assisted by self-assembly. Polymer 2006, 47, 728-734.
6. BeMiller, J.N. An introduction to pectins: Structure and properties. In Chemistry and Function of Pectins; ACS Symposium Series-American Chemical Society: Washington, DC, USA, 1986; Volume 310, pp. 2-12.
7. Sriamornsak, P.; Sungthongjeen, S.; Puttipipatkhachorn, S. Use of pectin as a carrier for intragastric floating drug delivery: Carbonate salt contained beads. Carbohydr. Polym. 2007, 67, 436-445.
8. Mennini, N.; Furlanetto, S.; Maestrelli, F.; Pinzauti, S.; Mura, P. Response surface methodology in the optimization of chitosan-Ca pectinate bead formulations. Eur. J. Pharm. Sci. 2008, 35, 318-325.
9. Kumar, M.; Mishra, R.K.; Banthia, A.K. Development of pectin based hydrogel membranes for biomedical applications. Int. J. Plast. Technol. 2010, 14, 213-223.
10. Cabrera, J.C.; Cambier, P.; Cutsem, P. Drug encapsulation in pectin hydrogel beads-A systematic study of simulated digestion media. Int. J. Pharm. Pharm. Sci. 2011, 3, 292-299.
11. Birch, N.P.; Schiffman, J.D. Characterization of self-assembled polyelectrolyte complex nanoparticles formed from chitosan and pectin. Langmuir 2014, 30, 3441-3447.
12. Jain, A.; Gulbake, A.; Shilpi, S.; Jain, A.; Hurkat, P.; Jain, S.K. A new horizon in modifcations of chitosan: Syntheses and applications. Crit. Rev. Ther. Drug Carrier Syst. 2013, 30, 91-181.
13. Liu, L.; Fishman, M.L.; Kost, J.; Hicks, K.B. Pectin-based systems for colon-specific drug delivery via oral route. Biomaterials 2003, 24, 3333-3343.
14. Grant, G.T.; Morris, E.R.; Rees, D.A.; Smith, P.J.; Thom, D. Biological interactions between polysaccharides and divalent cations: The egg-box model. FEBS Lett. 1973, 32, 195-198.
15. May, C.D. Industrial pectins: Sources, production and applications. Carbohydr. Polymers 1990, 12, 79-99.
16. Kohn, R. Ion binding on polyuronates-alginate and pectin. Pure Appl. Chem. 1975, 42, 371-397.
17. Niwa, K.; Takaya, T.; Morimoto, T.; Takada, K. Preparation and evaluation of a time-controlled release capsule made of ethylcellulose for colon delivery of drugs. J. Drug Target. 1995, 3, 83-89.
18. Chourasia, M.K.; Jain, S.K. Pharmaceutical approaches to colon targeted drug delivery systems. J. Pharm. Pharm. Sci. 2003, 6, 33-66.
19. Leclere, L.; van Cutsem, P.; Michiels, C. Anti-cancer activities of ph-or heat-modified pectin. Front. Pharmacol. 2013, 4, 128.
20. Yu, C.-Y.; Cao, H.; Zhang, X.-C.; Zhou, F.-Z.; Cheng, S.-X.; Zhang, X.-Z.; Zhuo, R.-X. Hybrid nanospheres and vesicles based on pectin as drug carriers. Langmuir 2009, 25, 11720-11726.
21. Maestrelli, F.; Cirri, M.; Corti, G.; Mennini, N.; Mura, P. Development of enteric-coated calcium pectinate microspheres intended for colonic drug delivery. Eur. J. Pharm. Biopharm. 2008, 69, 508-518.
22. Chaurasia, M.; Chourasia, M.; Jain, N.K.; Jain, A.; Soni, V.; Gupta, Y.; Jain, S. Methotrexate bearing calcium pectinate microspheres: A platform to achieve colon-specific drug release. Curr. Drug Deliv. 2008, 5, 215-219.
23. Souder, J.; Ellenbogen, W. Control of d-amphetamine sulphate sustained release capsule. Drug Stand. 1985, 26, 77-79.
24. Jain, A.; Jain, S.K.; Ganesh, N.; Barve, J.; Beg, A.M. Design and development of ligand-appended polysaccharidic nanoparticles for the delivery of oxaliplatin in colorectal cancer. Nanomedicine 2010, 6, 179-190.
25. Van den Mooter, G.; Samyn, C.; Kinget, R. The relation between swelling properties and enzymatic degradation of azo polymers designed for colon-specific drug delivery. Pharm. Res. 1994, 11, 1737-1741.
26. Momin, M.; Pundarikakshudu, K. In vitro studies on guar gum based formulation for the colon targeted delivery of sennosides. J. Pharm. Pharm. Sci. 2004, 7, 325-331.
27. Vichai, V.; Kirtikara, K. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat. Protoc. 2006, 1, 1112-1116.
28. Kalhapure, R.S.; Akamanchi, K.G. Oleic acid based heterolipid synthesis, characterization and application in self-microemulsifying drug delivery system. Int. J. Pharm. 2012, 425, 9-18.
29. Skehan, P.; Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J.T.; Bokesch, H.; Kenney, S.; Boyd, M.R. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 1990, 82, 1107-1112.
30. Li, X.; Xu, Y.; Chen, G.; Wei, P.; Ping, Q. Plga nanoparticles for the oral delivery of 5-fluorouracil using high pressure homogenization-emulsification as the preparation method and in vitro/in vivo studies. Drug Dev. Ind. Pharm. 2008, 34, 107-115.
31. Alsarra, I.A.; Yassin, A.E.; Abdel-Hamid, M.; Alanazi, F.K.; Aljuffali, I.A. Direct UPLC-MS-MS validated method for the quantification of 5-aminolevulinic acid: Application to in vitro assessment of colonic-targeted oral tablets. J. Chromatogr. Sci. 2011, 49, 428-433.
32. Bajpai, A.; Shukla, S.K.; Bhanu, S.; Kankane, S. Responsive polymers in controlled drug delivery. Prog. Polym. Sci. 2008, 33, 1088-1118.
33. Sharma, V.K.; Jain, A.; Soni, V. Nano-aggregates: Emerging delivery tools for tumor therapy. Crit. Rev. Ther. Drug Carrier Syst. 2013, 30, 535-563.
34. Licht, T.R.; Hansen, M.; Bergström, A.; Poulsen, M.; Krath, B.N.; Markowski, J.; Dragsted, L.O.; Wilcks, A. Effects of apples and specific apple components on the cecal environment of conventional rats: Role of apple pectin. BMC Microbiol. 2010, 10, 13.
35. Kotla, N.G.; Gulati, M.; Singh, S.K.; Shivapooja, A. Facts, fallacies and future of dissolution testing of polysaccharide based colon-specific drug delivery. J. Controll. Release 2014, 178, 55-62.
36. Paharia, A.; Yadav, A.K.; Rai, G.; Jain, S.K.; Pancholi, S.S.; Agrawal, G.P. Eudragit-coated pectin microspheres of 5-fluorouracil for colon targeting. AAPS PharmSciTech 2007, 8, 12.
37. Dutta, R.K.; Sahu, S. Development of a novel probe sonication assisted enhanced loading of 5-FU in SPION encapsulated pectin nanocarriers for magnetic targeted drug delivery system. Eur. J. Pharm. Biopharm. 2012, 82, 58-65.
38. Voigt, W. Sulforhodamine B assay and chemosensitivity. In Chemosensitivity; Springer: Berlin/Heidelberg, Germany, 2005; pp. 39-48.
39. Bergman, M.; Djaldetti, M.; Salman, H.; Bessler, H. Effect of citrus pectin on malignant cell proliferation. Biomed. Pharmacother. 2010, 64, 44-47.
40. Olano-Martin, E.; Rimbach, G.H.; Gibson, G.R.; Rastall, R.A. Pectin and pectic-oligosaccharides induce apoptosis in in vitro human colonic adenocarcinoma cells. Anticancer Res. 2002, 23, 341-346.
41. Cheng, H.; Li, S.; Fan, Y.; Gao, X.; Hao, M.; Wang, J.; Zhang, X.; Tai, G.; Zhou, Y. Comparative studies of the antiproliferative effects of ginseng polysaccharides on HT-29 human colon cancer cells. Med. Oncol. 2011, 28, 175-181.
42. Yoo, J.-W.; Giri, N.; Lee, C.H. Ph-sensitive eudragit nanoparticles for mucosal drug delivery. Int. J. Pharm. 2011, 403, 262-267.
43. Jain, S.K.; Jain, A.; Gupta, Y.; Ahirwar, M. Design and development of hydrogel beads for targeted drug delivery to the colon. AAPS PharmSciTech 2007, 8, E56.
44. Vaidya, A.; Jain, A.; Khare, P.; Agrawal, R.K.; Jain, S.K. Metronidazole loaded pectin microspheres for colon targeting. J. Pharm. Sci. 2009, 98, 4229-4236.
45. He, W.; Du, Q.; Cao, D.-Y.; Xiang, B.; Fang, F. Pectin/ethylcellulose as film coatings for colon-specific drug delivery: Preparation and in vitro evaluation using 5-fluorouracil pellets. PDA J. Pharm. Sci. Technol./PDA 2007, 61, 121-130.
46. Bose, A.; Elyagoby, A.; Wong, T.W. Oral 5-fluorouracil colon-specific delivery through in vivo pellet coating for colon cancer and aberrant crypt foci treatment. Int. J. Pharm. 2014, 468, 178-186.
47. Zinutti, C.; Barberi-Heyob, M.; Hoffman, M.; Maincent, P. In-vivo evaluation of sustained release microspheres of 5-FU in rabbits. Int. J. Pharm. 1998, 166, 231-234.
48. Haupt, S.M.; Rubinstein, A. The colon as a possible target for orally administered peptide and protein drugs. Crit. Rev. Ther. Drug Carrier Syst. 2002, 19, 499-551.
49. Hoffart, V.; Lamprecht, A.; Maincent, P.; Lecompte, T.; Vigneron, C.; Ubrich, N. Oral bioavailability of a low molecular weight heparin using a polymeric delivery system. J. Controll. Release 2006, 113, 38-42.
50. Gupta, E.; Vyas, V.; Ahmed, F.; Sinko, P.; Cook, T.; Rubin, E. Pharmacokinetics of orally administered camptothecins. Ann. N. Y. Acad. Sci. 2000, 922, 195-204.
51. Lalloo, A.; Chao, P.; Hu, P.; Stein, S.; Sinko, P.J. Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins. J. Controll. Release 2006, 112, 333-342.