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Volumn 4, Issue 1, 2012, Pages 157-168

Pregabalin versus SSRIs and SNRIs in benzodiazepine-refractory outpatients with generalized anxiety disorder: A post hoc cost-effectiveness analysis in usual medical practice in Spain

Author keywords

Benzodiazepine refractory patients; Cost effectiveness; Generalized anxiety disorder; Pregabalin; Quality adjusted life years

Indexed keywords

BENZODIAZEPINE; CITALOPRAM; DULOXETINE; ESCITALOPRAM; FLUOXETINE; MIRTAZAPINE; PAROXETINE; PREGABALIN; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; VENLAFAXINE;

EID: 84930484524     PISSN: None     EISSN: 11786981     Source Type: Journal    
DOI: 10.2147/CEOR.S31102     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 54949154218 scopus 로고    scopus 로고
    • WFSBP task force on treatment guidelines for anxiety obsessive-compulsive post-traumatic stress disorders. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders-first revision
    • Bandelow B, Zohar J, Hollander E, Kasper S, Möller HJ, WFSBP task force on treatment guidelines for anxiety obsessive-compulsive post-traumatic stress disorders. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders-first revision. World J Biol Psychiatry. 2009;4:248-312.
    • (2009) World J Biol Psychiatry , vol.4 , pp. 248-312
    • Bandelow, B.1    Zohar, J.2    Hollander, E.3    Kasper, S.4    Möller, H.J.5
  • 2
  • 3
    • 0034966575 scopus 로고    scopus 로고
    • Consensus statement of generalized anxiety disorder from the international consensus group on depression and anxiety
    • Ballenger JC, Davidson JR, Lecrubier Y, et al. Consensus statement of generalized anxiety disorder from the international consensus group on depression and anxiety. J Clin Psychiatry. 2001;62 Suppl 11:53-58.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL 11 , pp. 53-58
    • Ballenger, J.C.1    Davidson, J.R.2    Lecrubier, Y.3
  • 4
    • 0036093608 scopus 로고    scopus 로고
    • Generalized anxiety and depression in primary care: Prevalence, recognition, and management
    • Wittchen HU, Kessler RC, Beesdo K, Krause P, Hofler M, Hoyer J. Generalized anxiety and depression in primary care: prevalence, recognition, and management. J Clin Psychiatry. 2002;63 Suppl 8:24-34.
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL 8 , pp. 24-34
    • Wittchen, H.U.1    Kessler, R.C.2    Beesdo, K.3    Krause, P.4    Hofler, M.5    Hoyer, J.6
  • 5
    • 4544300320 scopus 로고    scopus 로고
    • Prevalence of mental disorders in Europe: Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
    • Alonso J, Angermeyer MC, Bernert S, et al. Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand Suppl. 2004;Suppl 420:21-27.
    • (2004) Acta Psychiatr Scand Suppl , Issue.SUPPL 420 , pp. 21-27
    • Alonso, J.1    Angermeyer, M.C.2    Bernert, S.3
  • 6
    • 0036096018 scopus 로고    scopus 로고
    • Patterns and correlates of generalized anxiety disorder in community samples
    • Kessler RC, Wittchen HU. Patterns and correlates of generalized anxiety disorder in community samples. J Clin Psychiatry. 2002;63 Suppl 8:4-10.
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL 8 , pp. 4-10
    • Kessler, R.C.1    Wittchen, H.U.2
  • 8
    • 62749134473 scopus 로고    scopus 로고
    • Clinical prevalence and reason for visit of patients with generalized anxiety disorder seen in the psychiatry out-patient clinics in Spain. Results of the LIGANDO study
    • Spanish
    • Caballero L, Bobes J, Vilardaga I, Rejas J. Clinical prevalence and reason for visit of patients with generalized anxiety disorder seen in the psychiatry out-patient clinics in Spain. Results of the LIGANDO study. Actas Esp Psiquiatr. 2009;37:17-20. Spanish.
    • (2009) Actas Esp Psiquiatr , vol.37 , pp. 17-20
    • Caballero, L.1    Bobes, J.2    Vilardaga, I.3    Rejas, J.4
  • 9
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62:593-602.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 10
    • 19844367388 scopus 로고    scopus 로고
    • The epidemiology of generalized anxiety disorder in Europe
    • Lieb R, Becker E, Altamura C. The epidemiology of generalized anxiety disorder in Europe. Eur Neuropsychopharmacol. 2005;15:445-452.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 445-452
    • Lieb, R.1    Becker, E.2    Altamura, C.3
  • 11
    • 59149099752 scopus 로고    scopus 로고
    • Current considerations in the treatment of generalized anxiety disorder
    • Katzman MA. Current considerations in the treatment of generalized anxiety disorder. CNS Drugs. 2009;23:103-120.
    • (2009) CNS Drugs , vol.23 , pp. 103-120
    • Katzman, M.A.1
  • 12
    • 19944364229 scopus 로고    scopus 로고
    • Cost of anxiety disorders in Europe
    • Andlin-Sobocki P, Wittchen HU. Cost of anxiety disorders in Europe. Eur J Neurol. 2005;12 Suppl 1:39-44.
    • (2005) Eur J Neurol , vol.12 , Issue.SUPPL 1 , pp. 39-44
    • Andlin-Sobocki, P.1    Wittchen, H.U.2
  • 13
    • 33748974417 scopus 로고    scopus 로고
    • Overlap of anxiety and depression in a managed care population: Prevalence and association with resource utilization
    • McLaughlin TP, Khandker RK, Kruzikas DT, Tummala R. Overlap of anxiety and depression in a managed care population: prevalence and association with resource utilization. J Clin Psychiatry. 2006;67: 1187-1193.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1187-1193
    • McLaughlin, T.P.1    Khandker, R.K.2    Kruzikas, D.T.3    Tummala, R.4
  • 14
    • 0036907780 scopus 로고    scopus 로고
    • Generalized anxiety disorder: Prevalence, burden, and cost to society
    • Wittchen HU. Generalized anxiety disorder: prevalence, burden, and cost to society. Depress Anxiety. 2002;16:162-171.
    • (2002) Depress Anxiety , vol.16 , pp. 162-171
    • Wittchen, H.U.1
  • 15
    • 70349240864 scopus 로고    scopus 로고
    • Refractory generalized anxiety disorder
    • Pollack MH. Refractory generalized anxiety disorder. J Clin Psychiatry. 2009;70 Suppl 2:32-38.
    • (2009) J Clin Psychiatry , vol.70 , Issue.SUPPL 2 , pp. 32-38
    • Pollack, M.H.1
  • 16
    • 67649433595 scopus 로고    scopus 로고
    • First-line pharmacotherapy approaches for generalized anxiety disorder
    • Davidson JR. First-line pharmacotherapy approaches for generalized anxiety disorder. J Clin Psychiatry. 2009;70 Suppl 2:25-31.
    • (2009) J Clin Psychiatry , vol.70 , Issue.SUPPL 2 , pp. 25-31
    • Davidson, J.R.1
  • 17
    • 0027365016 scopus 로고
    • Antidepressants for the treatment of generalized anxiety disorder: A placebo-controlled comparison of imipramine, trazodone, and diazepam
    • Rickels K, Downing R, Schweizer E, Hassman H. Antidepressants for the treatment of generalized anxiety disorder: a placebo-controlled comparison of imipramine, trazodone, and diazepam. Arch Gen Psychiatry. 1993;50:884-895.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 884-895
    • Rickels, K.1    Downing, R.2    Schweizer, E.3    Hassman, H.4
  • 18
    • 0029975930 scopus 로고    scopus 로고
    • The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel
    • Gee NS, Brown JP, Dissanayake VU, Offord J, Thurlow R, Woodruff GN. The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel. J Biol Chem. 1996;271:5768-5776.
    • (1996) J Biol Chem , vol.271 , pp. 5768-5776
    • Gee, N.S.1    Brown, J.P.2    Dissanayake, V.U.3    Offord, J.4    Thurlow, R.5    Woodruff, G.N.6
  • 19
    • 0033696481 scopus 로고    scopus 로고
    • Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin
    • Dooley DJ, Donovan CM, Pugsley TA. Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin. J Pharmacol Exp Ther. 2000;295:1086-1093.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1086-1093
    • Dooley, D.J.1    Donovan, C.M.2    Pugsley, T.A.3
  • 20
    • 0034972502 scopus 로고    scopus 로고
    • Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudal trigeminal nucleus slices
    • Maneuf YP, Hughes J, McKnight AT. Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudal trigeminal nucleus slices. Pain. 2001;93:91-96.
    • (2001) Pain , vol.93 , pp. 91-96
    • Maneuf, Y.P.1    Hughes, J.2    McKnight, A.T.3
  • 21
    • 0036166869 scopus 로고    scopus 로고
    • Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex
    • Fink K, Dooley DJ, Meder WP, et al. Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex. Neuropharmacology. 2002;42:229-236.
    • (2002) Neuropharmacology , vol.42 , pp. 229-236
    • Fink, K.1    Dooley, D.J.2    Meder, W.P.3
  • 22
    • 59649104976 scopus 로고    scopus 로고
    • Cost-of-illness studies and cost-effectiveness analyses in anxiety disorders: A systematic review
    • Konnopka A, Leichsenring F, Leibing E, König HH. Cost-of-illness studies and cost-effectiveness analyses in anxiety disorders: a systematic review. J Affect Disord. 2009;114:14-31.
    • (2009) J Affect Disord , vol.114 , pp. 14-31
    • Konnopka, A.1    Leichsenring, F.2    Leibing, E.3    König, H.H.4
  • 23
    • 76649091257 scopus 로고    scopus 로고
    • Cost-effectiveness of pregabalin versus venlafaxine in the treatment of generalized anxiety disorder: Findings from a Spanish perspective
    • Vera-Llonch M, Dukes E, Rejas J, Sofrygin O, Mychaskiw M, Oster G. Cost-effectiveness of pregabalin versus venlafaxine in the treatment of generalized anxiety disorder: findings from a Spanish perspective. Eur J Health Econ. 2010;11:35-44.
    • (2010) Eur J Health Econ , vol.11 , pp. 35-44
    • Vera-Llonch, M.1    Dukes, E.2    Rejas, J.3    Sofrygin, O.4    Mychaskiw, M.5    Oster, G.6
  • 24
    • 77957686810 scopus 로고    scopus 로고
    • Broadening of generalized anxiety disorders definition does not affect the response to therapy: Findings from the ADAN study
    • Abstract PW01-50
    • Álvarez E, Carrasco JL, Olivares JM, et al. Broadening of generalized anxiety disorders definition does not affect the response to therapy: findings from the ADAN study. Eur Psychiatry. 2010;25 Suppl 1:Abstract PW01-50.
    • (2010) Eur Psychiatry , vol.25 , Issue.SUPPL 1
    • Álvarez, E.1    Carrasco, J.L.2    Olivares, J.M.3
  • 25
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 26
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32:50-55.
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 27
    • 0037070878 scopus 로고    scopus 로고
    • Validación de las versiones en español de la Montgomery-Asberg Depression Scale y la Hamilton Anxiety Rating Scale para la evaluación de la depresión y de la ansiedad
    • Spanish
    • Lobo A, Chamorro L, Luque A, Dal-Ré R, Badía X, Baró E. Validación de las versiones en español de la Montgomery-Asberg Depression Scale y la Hamilton Anxiety Rating Scale para la evaluación de la depresión y de la ansiedad. Med Clin (Barc). 2002;118:493-499. Spanish.
    • (2002) Med Clin (Barc) , vol.118 , pp. 493-499
    • Lobo, A.1    Chamorro, L.2    Luque, A.3    dal-Ré, R.4    Badía, X.5    Baró, E.6
  • 28
    • 0003412410 scopus 로고
    • Rockville, MD: US Department of Health Education, and Welfare, Psychopharmacology Research Branch
    • Guy W. ECDEU Assessment Manual for Psychopharmacology Revised. Rockville, MD: US Department of Health Education, and Welfare, Psychopharmacology Research Branch; 1976.
    • (1976) ECDEU Assessment Manual for Psychopharmacology Revised
    • Guy, W.1
  • 29
    • 0025688231 scopus 로고
    • EuroQoL-a new facility for the measurement of health-related quality of life
    • EuroQoL Group
    • EuroQoL Group. EuroQoL-a new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199-208.
    • (1990) Health Policy , vol.16 , pp. 199-208
  • 30
    • 0006942658 scopus 로고    scopus 로고
    • The Spanish version of EuroQoL: A description and its applications. European Quality of Life scale
    • Spanish
    • Badía X, Roset M, Montserrat S, Herdman M, Segura A. The Spanish version of EuroQoL: a description and its applications. European Quality of Life scale. Med Clin (Barc). 1999;112 Suppl 1:79-85. Spanish.
    • (1999) Med Clin (Barc) , vol.112 , Issue.SUPPL 1 , pp. 79-85
    • Badía, X.1    Roset, M.2    Montserrat, S.3    Herdman, M.4    Segura, A.5
  • 32
    • 84930473836 scopus 로고    scopus 로고
    • note
    • Catálogo del Consejo General de Colegios Farmacéuticos de España, BOT base de datos del medicamento 2008.
  • 33
    • 84863906180 scopus 로고    scopus 로고
    • eSALUD. Base de datos de costes sanitarios. In: Social, S.C.d.E.e.E.d.l.S.y.P. editor. Soikos, Barcelona
    • Oblikue, 2008. eSALUD. Base de datos de costes sanitarios. In: Social, S.C.d.E.e.E.d.l.S.y.P. editor. Soikos, Barcelona.
    • (2008) Oblikue
  • 34
    • 84930475507 scopus 로고    scopus 로고
    • INE, Spain, Accessed Aug 2008
    • INE. [http://www.ine.es] Spain 2008. Accessed Aug 2008.
    • (2008)
  • 35
    • 76649121621 scopus 로고    scopus 로고
    • Relationship between anxiety severity and health utility index scores in generalized anxiety disorder
    • Presented at the, Chicago, IL; July 9-13
    • Revicki D, Brandenburg M, Matza LS, et al. Relationship between anxiety severity and health utility index scores in generalized anxiety disorder. Presented at the Collegium of Internationale Neuro-Psycharmacologicum, Chicago, IL; July 9-13, 2006.
    • (2006) Collegium of Internationale Neuro-Psycharmacologicum
    • Revicki, D.1    Brandenburg, M.2    Matza, L.S.3
  • 37
    • 77950296007 scopus 로고    scopus 로고
    • A proposed guideline for economic evaluation of health technologies
    • Spanish
    • Bastida JL, Oliva J, Antoñanzas F, et al. A proposed guideline for economic evaluation of health technologies. Gac Sanit. 2010;24:154-170. Spanish.
    • (2010) Gac Sanit , vol.24 , pp. 154-170
    • Bastida, J.L.1    Oliva, J.2    Antoñanzas, F.3
  • 38
    • 70349337426 scopus 로고    scopus 로고
    • Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disorders
    • Gao K, Sheehan DV, Calabrese JR. Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disorders. Expert Rev Neurother. 2009;9:1147-1158.
    • (2009) Expert Rev Neurother , vol.9 , pp. 1147-1158
    • Gao, K.1    Sheehan, D.V.2    Calabrese, J.R.3
  • 39
    • 4444220375 scopus 로고    scopus 로고
    • Cost-effectiveness of psychological and pharmacological interventions for generalized anxiety disorder and panic disorder
    • Heuzenröeder L, Donnelly M, Haby MM, et al. Cost-effectiveness of psychological and pharmacological interventions for generalized anxiety disorder and panic disorder. Psychiatry. 2004;38:602-612.
    • (2004) Psychiatry , vol.38 , pp. 602-612
    • Heuzenröeder, L.1    Donnelly, M.2    Haby, M.M.3
  • 40
    • 0942266233 scopus 로고    scopus 로고
    • Modelling the population cost-effectiveness of current and evidence-based optimal treatment for anxiety disorders
    • Issakidis C, Sanderson K, Corry J, Andrews G, Lapsley H. Modelling the population cost-effectiveness of current and evidence-based optimal treatment for anxiety disorders. Psychol. Med. 2004;34:19-35.
    • (2004) Psychol. Med , vol.34 , pp. 19-35
    • Issakidis, C.1    Sanderson, K.2    Corry, J.3    Andrews, G.4    Lapsley, H.5
  • 41
    • 21344462877 scopus 로고    scopus 로고
    • Cost-effectiveness of venlafaxine XL compared with diazepam in the treatment of generalized anxiety disorder in the United Kingdom
    • Guest JF, Russ J, Lenox-Smith A. Cost-effectiveness of venlafaxine XL compared with diazepam in the treatment of generalized anxiety disorder in the United Kingdom. Eur J Health Econ. 2005;6:136-145.
    • (2005) Eur J Health Econ , vol.6 , pp. 136-145
    • Guest, J.F.1    Russ, J.2    Lenox-Smith, A.3
  • 42
    • 33749593931 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of escitalopram compared with paroxetine in treatment of generalized anxiety disorder in the United Kingdom
    • Jørgensen TR, Stein DJ, Despiegel N, Drost PB, Hemels ME, Baldwin DS. Cost-effectiveness analysis of escitalopram compared with paroxetine in treatment of generalized anxiety disorder in the United Kingdom. Ann Pharmacother. 2006;40:1752-1758.
    • (2006) Ann Pharmacother , vol.40 , pp. 1752-1758
    • Jørgensen, T.R.1    Stein, D.J.2    Despiegel, N.3    Drost, P.B.4    Hemels, M.E.5    Baldwin, D.S.6
  • 43
    • 63849233377 scopus 로고    scopus 로고
    • Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: Results of a double-blind, placebo-controlled 8-week trial
    • Baldinetti F, Bandelow B, Kasper S, et al. Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: results of a double-blind, placebo-controlled 8-week trial. Int Clin Psychopharmacol. 2009;24:87-96.
    • (2009) Int Clin Psychopharmacol , vol.24 , pp. 87-96
    • Baldinetti, F.1    Bandelow, B.2    Kasper, S.3
  • 44
    • 0037280384 scopus 로고    scopus 로고
    • Principles of good practice for decision analytic modelling in health care evaluation: Report of the ISPOR Task Force on good research practices-modeling studies
    • ISPOR Task Force on Good Research Practices
    • Weinstein MC, O'Brien B, Hornberger J, etal; ISPOR Task Force on Good Research Practices. Principles of good practice for decision analytic modelling in health care evaluation: report of the ISPOR Task Force on good research practices-modeling studies. Value Health. 2003;6:9-17.
    • (2003) Value Health , vol.6 , pp. 9-17
    • Weinstein, M.C.1    O'Brien, B.2    Hornberger, J.3
  • 45
    • 4544286541 scopus 로고    scopus 로고
    • National Institute for Clinical Excellence, London, UK: National Institute for Clinical Excellence
    • National Institute for Clinical Excellence. Guide to the Methods of Technology Appraisal. London, UK: National Institute for Clinical Excellence; 2004.
    • (2004) Guide to the Methods of Technology Appraisal
  • 46
    • 41749104179 scopus 로고    scopus 로고
    • Novel treatment approaches for refractory anxiety disorders
    • Pollack MH, Otto MW, Roy-Byrne PP, et al. Novel treatment approaches for refractory anxiety disorders. Depress Anxiety. 2008;25:467-476.
    • (2008) Depress Anxiety , vol.25 , pp. 467-476
    • Pollack, M.H.1    Otto, M.W.2    Roy-Byrne, P.P.3
  • 47
    • 41849148995 scopus 로고    scopus 로고
    • Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: Preliminary findings
    • Simon NM, Connor KM, LeBeau RT, et al. Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: preliminary findings. Psychopharmacology (Berl). 2008;197:675-681.
    • (2008) Psychopharmacology (Berl) , vol.197 , pp. 675-681
    • Simon, N.M.1    Connor, K.M.2    LeBeau, R.T.3
  • 48
    • 32144450616 scopus 로고    scopus 로고
    • Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: A placebo controlled study
    • Pollack MH, Simon NM, Zalta AK, et al. Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: a placebo controlled study. Biol Psychiatry. 2006;59:211-215.
    • (2006) Biol Psychiatry , vol.59 , pp. 211-215
    • Pollack, M.H.1    Simon, N.M.2    Zalta, A.K.3


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