Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

Journal of the American Society of Nephrology

Volumn 26, Issue 6, 2015, Pages 1304-1321

  Zhan, Ming ^a   Usman, Irtaza M ^a   Sun, Lin ^a   Kanwar, Yashpal S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYTOCHROME C; DNA NUCLEOTIDYLEXOTRANSFERASE; GLUCOSE; INOSITOL OXYGENASE; MITOFUSIN 2; PARKIN; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; SACCHARIC ACID; SMALL INTERFERING RNA; GLUCURONIC ACID; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DAMAGE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ELECTRIC POTENTIAL; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; KIDNEY FUNCTION; KIDNEY TUBULE CELL; LLC PK1 CELL LINE; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MITOPHAGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; QUALITY CONTROL; RENAL DIABETES; RENAL TUBULAR MITOCHONDRIAL QUALITY; TUNEL ASSAY; UPREGULATION; ANIMAL; CELL CULTURE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY FUNCTION TEST; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PIG; RANDOMIZATION; SENSITIVITY AND SPECIFICITY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLUCURONATES; IMMUNOHISTOCHEMISTRY; INOSITOL OXYGENASE; KIDNEY FUNCTION TESTS; KIDNEY TUBULES; LLC-PK1 CELLS; MALE; MICE; MICE, INBRED ICR; MITOCHONDRIA; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; SENSITIVITY AND SPECIFICITY; STREPTOZOCIN; SWINE; UP-REGULATION;

EID: 84930462727     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2014050457     Document Type: Article

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