Microglia disrupt mesolimbic reward circuitry in chronic pain

Journal of Neuroscience

Volumn 35, Issue 22, 2015, Pages 8442-8450

  Taylor, Anna M W ^a,b   Castonguay, Annie ^c,d   Taylor, Alison J ^b   Murphy, Niall P ^b   Ghogha, Atefeh ^b   Cook, Christopher ^a   Xue, Lihua ^e   Olmstead, Mary C ^e   de Koninck, Yves ^c,d   Evans, Christopher J ^b   Cahill, Catherine M ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

^d UNIVERSITÉ LAVAL   (Canada)

^e QUEEN S UNIVERSITY   (Canada)

Author keywords

Addiction; Affective disorder; Chronic pain; Dopamine; Emotion; Opioids

Indexed keywords

AMPHETAMINE; COCAINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MINOCYCLINE; MORPHINE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 2;

ALLODYNIA; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CHLORIDE TRANSPORT; CHRONIC PAIN; DOPAMINERGIC TRANSMISSION; EVOKED RESPONSE; FLUORESCENCE MICROSCOPY; GABAERGIC SYSTEM; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; INTERNEURON; LIMBIC SYSTEM; MALE; MICRODIALYSIS; MICROGLIA; MOUSE; NERVE CELL NETWORK; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; REWARD; THERMAL STIMULUS TEST; ANIMAL; AREA UNDER THE CURVE; C57BL MOUSE; COMPLICATION; CONDITIONED REFLEX; DISEASE MODEL; DRUG EFFECTS; GENETICS; HYPERALGESIA; METABOLISM; NUCLEUS ACCUMBENS; PAIN THRESHOLD; PATHOLOGY; PHYSIOLOGY; SCIATIC NEUROPATHY; SPRAGUE DAWLEY RAT; TRANSGENIC MOUSE; VENTRAL TEGMENTUM;

ANIMALS; AREA UNDER CURVE; CHRONIC PAIN; COCAINE; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; GLUTAMATE DECARBOXYLASE; HYPERALGESIA; LIMBIC SYSTEM; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MINOCYCLINE; MORPHINE; NERVE NET; NUCLEUS ACCUMBENS; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; REWARD; SCIATIC NEUROPATHY; VENTRAL TEGMENTAL AREA;

EID: 84930446191     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4036-14.2015     Document Type: Article

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