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Volumn 35, Issue 22, 2015, Pages 8593-8603

Persistent nociception triggered by nerve growth factor (NGF) is mediated by TRPV1 and oxidative mechanisms

Author keywords

Allodynia; Arachidonic acid; Hyperalgesia; Linoleic acid; Nerve growth factor; TRPV1

Indexed keywords

ANISOMYCIN; ARACHIDONIC ACID; CALCITONIN; CAPSAICIN; CYCLOHEXIMIDE; LINOLEIC ACID; NERVE GROWTH FACTOR; VANILLOID RECEPTOR 1; AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; CALCITONIN GENE RELATED PEPTIDE; PROTEIN SYNTHESIS INHIBITOR; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

EID: 84930422767     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3993-14.2015     Document Type: Article
Times cited : (90)

References (55)
  • 1
    • 0026579864 scopus 로고
    • Nerve growth factor in the synovial fluid of patients with chronic arthritis
    • CrossRef Medline
    • Aloe L, Tuveri MA, Carcassi U, Levi-Montalcini R (1992) Nerve growth factor in the synovial fluid of patients with chronic arthritis. Arthritis and Rheumatism 35:351–355.CrossRef Medline
    • (1992) Arthritis and Rheumatism , vol.35 , pp. 351-355
    • Aloe, L.1    Tuveri, M.A.2    Carcassi, U.3    Levi-Montalcini, R.4
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • CrossRef Medline
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248 –254.CrossRef Medline
    • (1976) Anal Biochem , vol.72
    • Bradford, M.M.1
  • 4
    • 0032403179 scopus 로고    scopus 로고
    • Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS
    • CrossRef Medline
    • Bylund J, Ericsson J, Oliw EH (1998) Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS. Anal Biochem 265:55– 68.CrossRef Medline
    • (1998) Anal Biochem , vol.265
    • Bylund, J.1    Ericsson, J.2    Oliw, E.H.3
  • 5
    • 76749118433 scopus 로고    scopus 로고
    • Tanezumab, a recombinant humanized mAb against nerve growth factor for the treatment of acute and chronic pain
    • Cattaneo A (2010) Tanezumab, a recombinant humanized mAb against nerve growth factor for the treatment of acute and chronic pain. Curr Opin Mol Ther 12:94 –106.
    • (2010) Curr Opin Mol Ther , vol.12
    • Cattaneo, A.1
  • 7
    • 0037899137 scopus 로고    scopus 로고
    • NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
    • CrossRef Medline
    • Delcroix JD, Valletta JS, Wu C, Hunt SJ, Kowal AS, Mobley WC (2003) NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals. Neuron 39:69–84.CrossRef Medline
    • (2003) Neuron , vol.39 , pp. 69-84
    • Delcroix, J.D.1    Valletta, J.S.2    Wu, C.3    Hunt, S.J.4    Kowal, A.S.5    Mobley, W.C.6
  • 8
    • 1642286206 scopus 로고    scopus 로고
    • The vanilloid receptor-1 (TRPV1) is expressed in some rat dorsal horn NK1 cells
    • CrossRef Medline
    • Doly S, Fischer J, Conrath M (2004) The vanilloid receptor-1 (TRPV1) is expressed in some rat dorsal horn NK1 cells. Brain Res 1004:203–207.CrossRef Medline
    • (2004) Brain Res , vol.1004 , pp. 203-207
    • Doly, S.1    Fischer, J.2    Conrath, M.3
  • 10
    • 0031020724 scopus 로고    scopus 로고
    • Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heat-pain threshold in humans
    • CrossRef Medline
    • Dyck PJ, Peroutka S, Rask C, Burton E, Baker MK, Lehman KA, Gillen DA, Hokanson JL, O’Brien PC (1997) Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heat-pain threshold in humans. Neurology 48:501–505.CrossRef Medline
    • (1997) Neurology , vol.48 , pp. 501-505
    • Dyck, P.J.1    Peroutka, S.2    Rask, C.3    Burton, E.4    Baker, M.K.5    Lehman, K.A.6    Gillen, D.A.7    Hokanson, J.L.8    O’Brien, P.C.9
  • 11
    • 0142043854 scopus 로고    scopus 로고
    • Spinal delivery of analgesics in experimental models of pain and analgesia
    • CrossRef Medline
    • Fairbanks CA (2003) Spinal delivery of analgesics in experimental models of pain and analgesia. Adv Drug Deliv Rev 55:1007–1041.CrossRef Medline
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 1007-1041
    • Fairbanks, C.A.1
  • 12
    • 33748804968 scopus 로고    scopus 로고
    • Inhibitors of brain phospholipase A2 activity: Their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders
    • CrossRef Medline
    • Farooqui AA, Ong WY, Horrocks LA (2006) Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders. Pharmacol Rev 58: 591–620.CrossRef Medline
    • (2006) Pharmacol Rev , vol.58 , pp. 591-620
    • Farooqui, A.A.1    Ong, W.Y.2    Horrocks, L.A.3
  • 13
    • 33746834598 scopus 로고    scopus 로고
    • Attenuation of capsaicinevoked mechanical allodynia by peripheral neuropeptide Y Y1 receptors
    • CrossRef Medline
    • Gibbs JL, Flores CM, Hargreaves KM (2006) Attenuation of capsaicinevoked mechanical allodynia by peripheral neuropeptide Y Y1 receptors. Pain 124:167–174.CrossRef Medline
    • (2006) Pain , vol.124 , pp. 167-174
    • Gibbs, J.L.1    Flores, C.M.2    Hargreaves, K.M.3
  • 14
    • 0027959041 scopus 로고
    • Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation
    • CrossRef Medline
    • Goodman Y, Steiner MR, Steiner SM, Mattson MP (1994) Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation. Brain Res 654:171–176.CrossRef Medline
    • (1994) Brain Res , vol.654 , pp. 171-176
    • Goodman, Y.1    Steiner, M.R.2    Steiner, S.M.3    Mattson, M.P.4
  • 15
    • 84886233924 scopus 로고    scopus 로고
    • Role of endogenous TRPV1 agonists in a postburn pain model of partialthickness injury
    • CrossRef Medline
    • Green DP, Ruparel S, Roman L, Henry MA, Hargreaves KM (2013) Role of endogenous TRPV1 agonists in a postburn pain model of partialthickness injury. Pain 154:2512–2520.CrossRef Medline
    • (2013) Pain , vol.154 , pp. 2512-2520
    • Green, D.P.1    Ruparel, S.2    Roman, L.3    Henry, M.A.4    Hargreaves, K.M.5
  • 17
    • 0023924046 scopus 로고
    • Anew and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • CrossRef Medline
    • Hargreaves K, Dubner R, Brown F, Flores C, Joris J (1988)Anew and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77– 88.CrossRef Medline
    • (1988) Pain , vol.32
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 18
    • 30744447922 scopus 로고    scopus 로고
    • Time course and dose-dependence of nerve growth factor-induced secondary hyperalgesia in the mouse
    • Hathway GJ, Fitzgerald M (2006) Time course and dose-dependence of nerve growth factor-induced secondary hyperalgesia in the mouse. J Pain 7:57– 61.
    • (2006) J Pain , vol.7
    • Hathway, G.J.1    Fitzgerald, M.2
  • 19
    • 57549118558 scopus 로고    scopus 로고
    • The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor
    • CrossRef Medline
    • Medline Holzer P (2008) The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor. Br J Pharmacol 155:1145– 1162.CrossRef Medline
    • (2008) Br J Pharmacol , vol.155
    • Medline Holzer, P.1
  • 20
    • 23044496253 scopus 로고    scopus 로고
    • A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats
    • CrossRef Medline
    • Honore P, Wismer CT, Mikusa J, Zhu CZ, Zhong C, Gauvin DM, Gomtsyan A, El Kouhen R, Lee CH, Marsh K, Sullivan JP, Faltynek CR, Jarvis MF (2005) A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. J Pharmacol Exp Ther 314:410–421.CrossRef Medline
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 410-421
    • Honore, P.1    Wismer, C.T.2    Mikusa, J.3    Zhu, C.Z.4    Zhong, C.5    Gauvin, D.M.6    Gomtsyan, A.7    El Kouhen, R.8    Lee, C.H.9    Marsh, K.10    Sullivan, J.P.11    Faltynek, C.R.12    Jarvis, M.F.13
  • 22
    • 0036901970 scopus 로고    scopus 로고
    • Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140. TrkA) in human osteoarthritic chondrocytes
    • CrossRef Medline
    • Iannone F, De Bari C, Dell’Accio F, Covelli M, Patella V, Lo Bianco G, Lapadula G (2002) Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140. TrkA) in human osteoarthritic chondrocytes. Rheumatology (Oxford) 41:1413–1418.CrossRef Medline
    • (2002) Rheumatology (Oxford) , vol.41 , pp. 1413-1418
    • Iannone, F.1    De Bari, C.2    Dell’Accio, F.3    Covelli, M.4    Patella, V.5    Lo Bianco, G.6    Lapadula, G.7
  • 23
    • 0037179755 scopus 로고    scopus 로고
    • MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
    • CrossRef Medline
    • Ji RR, Samad TA, Jin SX, Schmoll R, Woolf CJ (2002) p38.MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36:57– 68.CrossRef Medline
    • (2002) Neuron , vol.36
    • Ji, R.R.1    Samad, T.A.2    Jin, S.X.3    Schmoll, R.4    Woolf, C.J.5
  • 24
    • 34447331071 scopus 로고    scopus 로고
    • Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia
    • CrossRef Medline
    • Kanai Y, Hara T, Imai A, Sakakibara A (2007) Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia. J Pharm Pharmacol 59:733–738.CrossRef Medline
    • (2007) J Pharm Pharmacol , vol.59 , pp. 733-738
    • Kanai, Y.1    Hara, T.2    Imai, A.3    Sakakibara, A.4
  • 25
    • 78649451203 scopus 로고    scopus 로고
    • Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids
    • CrossRef Medline
    • Konkel A, Schunck WH (2011) Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. Biochim Biophys Acta 1814: 210–222.CrossRef Medline
    • (2011) Biochim Biophys Acta , vol.1814 , pp. 210-222
    • Konkel, A.1    Schunck, W.H.2
  • 26
    • 0027406813 scopus 로고
    • Nerve growth factor-induced hyperalgesia in the neonatal and adult rat
    • Lewin GR, Ritter AM, Mendell LM (1993) Nerve growth factor-induced hyperalgesia in the neonatal and adult rat. J Neurosci 13:2136 –2148.
    • (1993) J Neurosci , vol.13
    • Lewin, G.R.1    Ritter, A.M.2    Mendell, L.M.3
  • 28
    • 17844366313 scopus 로고    scopus 로고
    • Spinal phospholipase A2 in inflammatory hyperalgesia: Role of group IVA cPLA2
    • CrossRef Medline
    • Lucas KK, Svensson CI, Hua XY, Yaksh TL, Dennis EA (2005) Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2. Br J Pharmacol 144:940 –952.CrossRef Medline
    • (2005) Br J Pharmacol , vol.144
    • Lucas, K.K.1    Svensson, C.I.2    Hua, X.Y.3    Yaksh, T.L.4    Dennis, E.A.5
  • 30
    • 79959509581 scopus 로고    scopus 로고
    • Antagonism of nerve growth factor-TrkA signaling and the relief of pain
    • CrossRef Medline
    • Mantyh PW, Koltzenburg M, Mendell LM, Tive L, Shelton DL (2011) Antagonism of nerve growth factor-TrkA signaling and the relief of pain. Anesthesiology 115:189 –204.CrossRef Medline
    • (2011) Anesthesiology , vol.115
    • Mantyh, P.W.1    Koltzenburg, M.2    Mendell, L.M.3    Tive, L.4    Shelton, D.L.5
  • 31
    • 57449098039 scopus 로고    scopus 로고
    • Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats
    • CrossRef Medline
    • McGaraughty S, Chu KL, Brown BS, Zhu CZ, Zhong C, Joshi SK, Honore P, Faltynek CR, Jarvis MF (2008) Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats. J Neurophysiol 100:3158 –3166.CrossRef Medline
    • (2008) J Neurophysiol , vol.100
    • McGaraughty, S.1    Chu, K.L.2    Brown, B.S.3    Zhu, C.Z.4    Zhong, C.5    Joshi, S.K.6    Honore, P.7    Faltynek, C.R.8    Jarvis, M.F.9
  • 33
    • 84877632648 scopus 로고    scopus 로고
    • Neuroprotection induced by N-acetylcysteine against cytosolic glutathione depletion-induced Ca2 influx in dorsal root ganglion neurons of mice: Role of TRPV1 channels
    • CrossRef Medline
    • Nazıroglu M, Cig B, Ozgul C (2013) Neuroprotection induced by N-acetylcysteine against cytosolic glutathione depletion-induced Ca2 influx in dorsal root ganglion neurons of mice: role of TRPV1 channels. Neuroscience 242:151–160.CrossRef Medline
    • (2013) Neuroscience , vol.242 , pp. 151-160
    • Nazıroglu, M.1    Cig, B.2    Ozgul, C.3
  • 34
    • 33847618699 scopus 로고    scopus 로고
    • Unraveling the story of NGF-mediated sensitization of nociceptive sensory neurons: ON or OFF the Trks?
    • CrossRef Medline
    • Nicol GD, Vasko MR (2007) Unraveling the story of NGF-mediated sensitization of nociceptive sensory neurons: ON or OFF the Trks? Mol Interv 7:26–41.CrossRef Medline
    • (2007) Mol Interv , vol.7 , pp. 26-41
    • Nicol, G.D.1    Vasko, M.R.2
  • 35
    • 62149117624 scopus 로고    scopus 로고
    • Facilitated neurotrophin release in sensitized human skin
    • CrossRef Medline
    • Paterson S, Schmelz M, McGlone F, Turner G, Rukwied R (2009) Facilitated neurotrophin release in sensitized human skin. Eur J Pain 13:399–405.CrossRef Medline
    • (2009) Eur J Pain , vol.13 , pp. 399-405
    • Paterson, S.1    Schmelz, M.2    McGlone, F.3    Turner, G.4    Rukwied, R.5
  • 36
    • 73249131229 scopus 로고    scopus 로고
    • Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia
    • CrossRef Medline
    • Patwardhan AM, Scotland PE, Akopian AN, Hargreaves KM (2009) Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia. Proc Natl Acad Sci U S A 106: 18820–18824.CrossRef Medline
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18820-18824
    • Patwardhan, A.M.1    Scotland, P.E.2    Akopian, A.N.3    Hargreaves, K.M.4
  • 39
    • 76349118547 scopus 로고    scopus 로고
    • NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin
    • CrossRef Medline
    • Rukwied R, Mayer A, Kluschina O, Obreja O, Schley M, Schmelz M (2010) NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin. Pain 148:407– 413.CrossRef Medline
    • (2010) Pain , vol.148
    • Rukwied, R.1    Mayer, A.2    Kluschina, O.3    Obreja, O.4    Schley, M.5    Schmelz, M.6
  • 40
    • 38749094588 scopus 로고    scopus 로고
    • Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors
    • CrossRef Medline
    • Ruparel NB, Patwardhan AM, Akopian AN, Hargreaves KM (2008) Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors. Pain 135:271– 279.CrossRef Medline
    • (2008) Pain , vol.135
    • Ruparel, N.B.1    Patwardhan, A.M.2    Akopian, A.N.3    Hargreaves, K.M.4
  • 41
    • 84866509194 scopus 로고    scopus 로고
    • The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolitemediated peripheral inflammatory pain
    • CrossRef Medline
    • Ruparel S, Green D, Chen P, Hargreaves KM (2012a) The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolitemediated peripheral inflammatory pain. Mol Pain 8:73.CrossRef Medline
    • (2012) Mol Pain , vol.8 , pp. 73
    • Ruparel, S.1    Green, D.2    Chen, P.3    Hargreaves, K.M.4
  • 42
    • 84866386978 scopus 로고    scopus 로고
    • Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation
    • CrossRef Medline
    • Ruparel S, Henry MA, Akopian A, Patil M, Zeldin DC, Roman L, Hargreaves KM (2012b) Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation. Pain 153:2031–2039.CrossRef Medline
    • (2012) Pain , vol.153 , pp. 2031-2039
    • Ruparel, S.1    Henry, M.A.2    Akopian, A.3    Patil, M.4    Zeldin, D.C.5    Roman, L.6    Hargreaves, K.M.7
  • 43
    • 34548380802 scopus 로고    scopus 로고
    • Increased levels of neurotrophins are not specific for chronic migraine: Evidence from primary fibromyalgia syndrome
    • CrossRef Medline
    • Sarchielli P, Mancini ML, Floridi A, Coppola F, Rossi C, Nardi K, Acciarresi M, Pini LA, Calabresi P (2007) Increased levels of neurotrophins are not specific for chronic migraine: evidence from primary fibromyalgia syndrome. J Pain 8:737–745.CrossRef Medline
    • (2007) J Pain , vol.8 , pp. 737-745
    • Sarchielli, P.1    Mancini, M.L.2    Floridi, A.3    Coppola, F.4    Rossi, C.5    Nardi, K.6    Acciarresi, M.7    Pini, L.A.8    Calabresi, P.9
  • 44
    • 0036172409 scopus 로고    scopus 로고
    • The spinal phospholipase-cyclooxygenaseprostanoid cascade in nociceptive processing
    • CrossRef Medline
    • Svensson CI, Yaksh TL (2002) The spinal phospholipase-cyclooxygenaseprostanoid cascade in nociceptive processing. Annu Rev Pharmacol Toxicol 42:553–583.CrossRef Medline
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 553-583
    • Svensson, C.I.1    Yaksh, T.L.2
  • 45
    • 0037823440 scopus 로고    scopus 로고
    • Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia
    • CrossRef Medline
    • Svensson P, Cairns BE, Wang K, Arendt-Nielsen L (2003) Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia. Pain 104:241–247.CrossRef Medline
    • (2003) Pain , vol.104 , pp. 241-247
    • Svensson, P.1    Cairns, B.E.2    Wang, K.3    Arendt-Nielsen, L.4
  • 46
    • 0028060282 scopus 로고
    • Pharmacokinetics of nerve growth factor (NGF) following different routes of administration to adult rats
    • CrossRef Medline
    • Tria MA, Fusco M, Vantini G, Mariot R (1994) Pharmacokinetics of nerve growth factor (NGF) following different routes of administration to adult rats. Exp Neurol 127:178 –183.CrossRef Medline
    • (1994) Exp Neurol 127:178 –183
    • Tria, M.A.1    Fusco, M.2    Vantini, G.3    Mariot, R.4
  • 47
    • 84859984051 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel
    • CrossRef Medline
    • Wen H, Ostman J, Bubb KJ, Panayiotou C, Priestley JV, Baker MD, Ahluwalia A (2012) 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel. J Biol Chem 287:13868 –13876.CrossRef Medline
    • (2012) J Biol Chem , vol.287
    • Wen, H.1    Ostman, J.2    Bubb, K.J.3    Panayiotou, C.4    Priestley, J.V.5    Baker, M.D.6    Ahluwalia, A.7
  • 48
    • 67349085734 scopus 로고    scopus 로고
    • The role of TRPV1 receptors in pain evoked by noxious thermal and chemical stimuli
    • CrossRef Medline
    • Willis WD Jr (2009) The role of TRPV1 receptors in pain evoked by noxious thermal and chemical stimuli. Exp Brain Res 196:5–11.CrossRef Medline
    • (2009) Exp Brain Res , vol.196 , pp. 5-11
    • Willis, W.D.1
  • 49
    • 0030605503 scopus 로고    scopus 로고
    • Phenotypic modification of primary sensory neurons: The role of nerve growth factor in the production of persistent pain. Philosophical Transactions of the Royal Society of London Series B
    • CrossRef Medline
    • Woolf CJ (1996) Phenotypic modification of primary sensory neurons: The role of nerve growth factor in the production of persistent pain. Philosophical Transactions of the Royal Society of London Series B, Biological Sciences 351:441– 448.CrossRef Medline
    • (1996) Biological Sciences , vol.351
    • Woolf, C.J.1
  • 50
    • 0029981215 scopus 로고    scopus 로고
    • Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation
    • Woolf CJ, Ma QP, Allchorne A, Poole S (1996) Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation. J Neurosci 16:2716 –2723.
    • (1996) J Neurosci , vol.16
    • Woolf, C.J.1    Ma, Q.P.2    Allchorne, A.3    Poole, S.4
  • 51
    • 0018601372 scopus 로고
    • Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia
    • CrossRef Medline
    • Medline Yaksh TL, Farb DH, Leeman SE, Jessell TM (1979) Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science 206:481– 483.CrossRef Medline
    • (1979) Science , vol.206
    • Medline Yaksh, T.L.1    Farb, D.H.2    Leeman, S.E.3    Jessell, T.M.4
  • 52
    • 57249108274 scopus 로고    scopus 로고
    • The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn
    • CrossRef Medline
    • Zhou HY, Chen SR, Chen H, Pan HL (2009) The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn. J Neurochem 108: 305–318.CrossRef Medline
    • (2009) J Neurochem , vol.108 , pp. 305-318
    • Zhou, H.Y.1    Chen, S.R.2    Chen, H.3    Pan, H.L.4
  • 53
    • 33947672465 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1
    • CrossRef Medline
    • Zhu W, Oxford GS (2007) Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1. Mol Cell Neurosci 34:689 –700.CrossRef Medline
    • (2007) Mol Cell Neurosci , vol.34
    • Zhu, W.1    Oxford, G.S.2
  • 54
    • 79960652915 scopus 로고    scopus 로고
    • Differential gene expression of neonatal and adultDRGneurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor
    • CrossRef Medline
    • Zhu W, Oxford GS (2011) Differential gene expression of neonatal and adultDRGneurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor. Neurosci Lett 500:192–196.CrossRef Medline
    • (2011) Neurosci Lett , vol.500 , pp. 192-196
    • Zhu, W.1    Oxford, G.S.2
  • 55
    • 14844303990 scopus 로고    scopus 로고
    • A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF
    • CrossRef Medline
    • Zhu W, Galoyan SM, Petruska JC, Oxford GS, Mendell LM (2004) A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF. J Neurophysiol 92:3148 –3152.CrossRef Medline
    • (2004) J Neurophysiol , vol.92
    • Zhu, W.1    Galoyan, S.M.2    Petruska, J.C.3    Oxford, G.S.4    Mendell, L.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.