Increased Levels of Neurotrophins Are Not Specific for Chronic Migraine: Evidence From Primary Fibromyalgia Syndrome

Journal of Pain

Volumn 8, Issue 9, 2007, Pages 737-745

  Sarchielli, Paola ^a   Mancini, Maria Luisa ^a   Floridi, Alessandro ^a   Coppola, Francesca ^a   Rossi, Cristiana ^a   Nardi, Katiuscia ^a,c   Acciarresi, Monica ^a,c   Pini, Luigi Alberto ^b   Calabresi, Paolo ^a,c  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

brain derived neurotrophic factor; cerebrospinal fluid; chronic migraine; fibromyalgia; glutamate; Nerve growth factor

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLUTAMIC ACID; NERVE GROWTH FACTOR; NEUROTROPHIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; FEMALE; FIBROMYALGIA; HUMAN; IMMUNOASSAY; MALE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; PATHOPHYSIOLOGY; PROTEIN CEREBROSPINAL FLUID LEVEL; TRANSFORMED MIGRAINE; UPREGULATION;

ADULT; BRAIN; BRAIN CHEMISTRY; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHRONIC DISEASE; FEMALE; FIBROMYALGIA; GLUTAMIC ACID; HUMANS; IMMUNOASSAY; MALE; MIGRAINE DISORDERS; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; PREDICTIVE VALUE OF TESTS; SYNAPTIC TRANSMISSION; UP-REGULATION;

EID: 34548380802     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2007.05.002     Document Type: Article

References (77)

1. Baranauskas G., and Nistri A. Sensitization of pain pathways in the spinal cord: Cellular mechanisms. Prog Neurobiol 54 (1998) 349-365
2. Bayliss M.S., and Batenhorst A.S. The HIT-6 TM: a user's guide (2002), Quality Metric, Lincoln, RI
3. Bennett D.L. Neurotrophic factors: Important regulators of nociceptive function. Neuroscientist 7 (2001) 13-17
4. Boes C.J., Black D.F., and Dodick D.W. Pathophysiology and management of transformed migraine and medication overuse headache. Semin Neurol 26 (2006) 232-241
5. Bradbury E.J., Burnstock G., and McMahon S.B. The expression of P2X3 purinoreceptors in sensory neurons: Effects of axotomy and glial-derived neurotrophic factor. Mol Cell Neurosci 12 (1998) 256-268
6. Brown A., Ricci M.J., and Weaver L.C. NGF message and protein distribution in the injured rat spinal cord. Exp Neurol 188 (2004) 115-127
7. Burckhardt C.S., Clark S.R., and Bennett R.M. The fibromyalgia impact questionnaire: Development and validation. J Rheumatol 18 (1991) 728-733
8. Chakrabarty K., Bhattacharyya S., Christopher R., and Khanna S. Glutamatergic dysfunction in OCD. Neuropsychopharmacology 30 (2005) 1735-1740
9. Chizh B.A. Novel approaches to targeting glutamate receptors for the treatment of chronic pain: Review article. Amino Acids 23 (2002) 169-176
10. Cleeland C.S., and Ryan K.M. Pain assessment: Global use of the Brief Pain Inventory. Ann Acad Med Singapore 23 (1994) 129-138
11. D'Amico D., Grazzi L., Usai S., Rigamonti A., Curone M., and Bussone G. Disability pattern in chronic migraine with medication overuse: A comparison with migraine without aura. Headache 45 (2005) 553-560
12. D'Amico D., Mosconi P., Genco S., Usai S., Prudenzano A.M., Grazzi L., Leone M., Puca F.M., and Bussone G. The Migraine Disability Assessment (MIDAS) questionnaire: Translation and reliability of the Italian version. Cephalalgia 21 (2001) 947-952
13. Dimitriadou V., Buzzi M.G., Theoharides T.C., and Moskowitz M.A. Ultrastructural evidence for neurogenically mediated changes in blood vessels of the rat dura mater and tongue following antidromic trigeminal stimulation. Neuroscience 48 (1992) 187-203
14. Fischer A.A. Pressure threshold meter: Its use for quantification of tender spots. Arch Phys Med Rehabil 67 (1986) 836-838
15. Gallai V., Alberti A., Gallai B., Coppola F., Floridi A., and Sarchielli P. Glutamate and nitric oxide pathway in chronic daily headache: Evidence from cerebrospinal fluid. Cephalalgia 23 (2003) 166-174
16. Garraway S.M., Petruska J.C., and Mendell L.M. BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs. Eur J Neurosci 18 (2003) 2467-2476
17. Giovengo S.L., Russell I.J., and Larson A.A. Increased concentrations of nerve growth factor in cerebrospinal fluid of patients with fibromyalgia. J Rheumatol 26 (1999) 1564-1569
18. Goadsby P.J. Migraine, allodynia, sensitisation and all of that .... Eur Neurol 53 Suppl 1 (2005) 10-16
19. Gould III H.J., Gould T.N., England J.D., Paul D., Liu Z.P., and Levinson S.R. A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain. Brain Res 854 (2000) 19-29
20. Guitera V., Munoz P., Castillo J., and Pascual J. Quality of life in chronic daily headache: a study in a general population. Neurology 58 (2002) 1062-1065
21. Hao J., Ebendal T., Xu X., Wiesenfeld-Hallin Z., and Eriksdotter Jonhagen M. Intracerebroventricular infusion of nerve growth factor induces pain-like response in rats. Neurosci Lett 286 (2000) 208-212
22. Hashimoto K., Engberg G., Shimizu E., Nordin C., Lindstrom L.H., and Iyo M. Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients. BMC Psychiatry 5 (2005) 6
23. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition. Cephalalgia 24 Suppl 1 (2004) 9-160
24. Horigome K., Pryor J.C., Bullock E.D., and Johnson Jr. E.M. Mediator release from mast cells by nerve growth factor: Neurotrophin specificity and receptor mediation. J Biol Chem 268 (1993) 14881-14887
25. Ifergane G., Buskila D., Simiseshvely N., Zeev K., and Cohen H. Prevalence of fibromyalgia syndrome in migraine patients. Cephalalgia 26 (2006) 451-456
26. Jarvis C.R., Xiong Z.G., Plant J.R., Churchill D., Lu W.Y., MacVicar B.A., and MacDonald J.F. Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. J Neurophysiol 78 (1997) 2363-2371
27. Kawamoto K., Aoki J., Tanaka A., Itakura A., Hosono H., Arai H., Kiso Y., and Matsuda H. Nerve growth factor activates mast cells through the collaborative interaction with lysophosphatidylserine expressed on the membrane surface of activated platelets. J Immunol 168 (2002) 6412-6419
28. Kerr B.J., Bradbury E.J., Bennett D.L., Trivedi P.M., Dassan P., French J., Shelton D.B., McMahon S.B., and Thompson S.W. Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord. J Neurosci 19 (1999) 5138-5148
29. Kitaj M.B., and Klink M. Pain thresholds in daily transformed migraine versus episodic migraine headache patients. Headache 45 (2005) 992-998
30. Kosinski M., Bayliss M.S., Bjorner J.B., Ware Jr. J.E., Garber W.H., Batenhorst A., Cady R., Dahlof C.G., Dowson A., and Tepper S. A six-item short-form survey for measuring headache impact: the HIT-6. Qual Life Res 12 (2003) 963-974
31. Leffler A., Cummins T.R., Dib-Hajj S.D., Hormuzdiar W.N., Black J.A., and Waxman S.G. GDNF and NGF reverse changes in repriming of TTX-sensitive Na(+) currents following axotomy of dorsal root ganglion neurons. J Neurophysiol 88 (2002) 650-658
32. Lever I., Cunningham J., Grist J., Yip P.K., and Malcangio M. Release of BDNF and GABA in the dorsal horn of neuropathic rats. Eur J Neurosci 18 (2003) 1169-1174
33. Lewin G.R., Rueff A., and Mendell L.M. Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur J Neurosci 6 (1994) 1903-1912
34. Lin S.Y., Wu K., Levine E.S., Mount H.T., Suen P.C., and Black I.B. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain Res Mol Brain Res 55 (1998) 20-27
35. Malcangio M. GDNF and somatostatin in sensory neurones. Curr Opin Pharmacol 3 (2003) 41-45
36. Malcangio M., and Lessmann V. A common thread for pain and memory synapses?. Brain-derived neurotrophic factor and trkB receptors. Trends Pharmacol Sci 24 (2003) 116-121
37. Malcangio M., Ramer M.S., Boucher T.J., and McMahon S.B. Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord. Eur J Neurosci 12 (2000) 139-144
38. Martinez F., Castillo J., Rodriguez J.R., Leira R., and Noya M. Neuroexcitatory amino acid levels in plasma and cerebrospinal fluid during migraine attacks. Cephalalgia 13 (1993) 89-93
39. Mathew N.T., Kailasam J., and Seifert T. Clinical recognition of allodynia in migraine. Neurology 63 (2004) 848-852
40. Mease P. Fibromyalgia syndrome: review of clinical presentation, pathogenesis, outcome measures, and treatment. J Rheumatol Suppl 75 (2005) 6-21
41. Mendell L.M., Albers K.M., and Davis B.M. Neurotrophins, nociceptors, and pain. Microsc Res Tech 45 (1999) 252-261
42. Merighi A., Carmignoto G., Gobbo S., Lossi L., Salio C., Vergnano A.M., and Zonta M. Neurotrophins in spinal cord nociceptive pathways. Prog Brain Res 146 (2004) 291-321
43. Michael G.J., Averill S., Nitkunan A., Rattray M., Bennett D.L., Yan Q., and Priestley J.V. Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord. J Neurosci 17 (1997) 8476-8490
44. Miklic S., Juric D.M., and Carman-Krzan M. Differences in the regulation of BDNF and NGF synthesis in cultured neonatal rat astrocytes. Int J Dev Neurosci 22 (2004) 119-130
45. Ogun-Muyiwa P., Helliwell R., McIntyre P., and Winter J. Glial cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons. Neuroreport 10 (1999) 2107-2111
46. Ozdinler P.H., Ulupinar E., and Erzurumlu R.S. Local neurotrophin effects on central trigeminal axon growth patterns. Brain Res Dev Brain Res 151 (2004) 55-66
47. Patz S., and Wahle P. Neurotrophins induce short-term and long-term changes of cortical neurotrophin expression. Eur J Neurosci 20 (2004) 701-708
48. Peres M.F., Zukerman E., Senne Soares C.A., Alonso E.O., Santos B.F., and Faulhaber M.H. Cerebrospinal fluid glutamate levels in chronic migraine. Cephalalgia 24 (2004) 735-739
49. Peveler R.C., and Fairburn C.G. Measurement of neurotic symptoms by self-report questionnaire: validity of the SCL-90R. Psychol Med 20 (1990) 873-879
50. Pezet S., Cunningham J., Patel J., Grist J., Gavazzi I., Lever I.J., and Malcangio M. BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn. Mol Cell Neurosci 21 (2002) 51-62
51. Pezet S., and Malcangio M. Brain-derived neurotrophic factor as a drug target for CNS disorders. Expert Opin Ther Targets 8 (2004) 391-399
52. Pezet S., and McMahon S.B. Neurotrophins: Mediators and modulators of pain. Annu Rev Neurosci 29 (2006) 507-538
53. Price D.D., and Staud R. Neurobiology of fibromyalgia syndrome. J Rheumatol Suppl 75 (2005) 22-28
54. Priestley J.V., Michael G.J., Averill S., Liu M., and Willmott N. Regulation of nociceptive neurons by nerve growth factor and glial cell line derived neurotrophic factor. Can J Physiol Pharmacol 80 (2002) 495-505
55. Rainesalo S., Keranen T., Palmio J., Peltola J., Oja S.S., and Saransaari P. Plasma and cerebrospinal fluid amino acids in epileptic patients. Neurochem Res 29 (2004) 319-324
56. Salter M.W. Cellular signalling pathways of spinal pain neuroplasticity as targets for analgesic development. Curr Top Med Chem 5 (2005) 557-567
57. Sarchielli P., Alberti A., Candeliere A., Floridi A., Capocchi G., and Calabresi P. Glial cell line-derived neurotrophic factor and somatostatin levels in cerebrospinal fluid of patients affected by chronic migraine and fibromyalgia. Cephalalgia 26 (2006) 409-415
58. Sarchielli P., Alberti A., Floridi A., and Gallai V. Levels of nerve growth factor in cerebrospinal fluid of chronic daily headache patients. Neurology 57 (2001) 132-134
59. Sarchielli P., Alberti A., Gallai B., Coppola F., Baldi A., Floridi A., and Gallai V. Brain-derived neurotrophic factor in cerebrospinal fluid of patients with chronic daily headache: relationship with nerve growth factor and glutamate levels. J Headache Pain 3 (2002) 129-135
60. Sarchielli P., and Gallai V. Nerve growth factor and chronic daily headache: a potential implication for therapy. Expert Rev Neurother 4 (2004) 115-127
61. Sarzi-Puttini P., Atzeni F., Fiorini T., Panni B., Randisi G., Turiel M., and Carrabba M. Validation of an Italian version of the Fibromyalgia Impact Questionnaire (FIQ-I). Clin Exp Rheumatol 21 (2003) 459-464
62. Shafer A.J., Crutcher K.A., and Isaacson L.G. Remodeling of adult sensory axons in the superior cervical ganglion in response to exogenous nerve growth factor. Brain Res 864 (2000) 252-262
63. Shu X.Q., and Mendell L.M. Neurotrophins and hyperalgesia. Proc Natl Acad Sci U S A 96 (1999) 7693-7696
64. Silberstein S.D. Migraine pathophysiology and its clinical implications. Cephalalgia 24 Suppl 2 (2004) 2-7
65. Skaper S.D., Pollock M., and Facci L. Mast cells differentially express and release active high molecular weight neurotrophins. Brain Res Mol Brain Res 97 (2001) 177-185
66. Staud R. Fibromyalgia pain: do we know the source?. Curr Opin Rheumatol 16 (2004) 157-163
67. Stewart W.F., Lipton R.B., Whyte J., Dowson A., Kolodner K., Liberman J.N., and Sawyer J. An international study to assess reliability of the Migraine Disability Assessment (MIDAS) score. Neurology 53 (1999) 988-994
68. Strombeck B., Ekdahl C., Manthorpe R., Wikstrom I., and Jacobsson L. Health-related quality of life in primary Sjogren's syndrome, rheumatoid arthritis and fibromyalgia compared to normal population data using SF-36. Scand J Rheumatol 29 (2000) 20-28
69. Theoharides T.C., Donelan J., Kandere-Grzybowska K., and Konstantinidou A. The role of mast cells in migraine pathophysiology. Brain Res Brain Res Rev 49 (2005) 65-76
70. Thompson S.W., Bennett D.L., Kerr B.J., Bradbury E.J., and McMahon S.B. Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord. Proc Natl Acad Sci U S A 96 (1999) 7714-7718
71. Tsai S.J. Possible involvement of brain-derived neurotrophic factor in the antinociceptive effect of antidepressants in neuropathic pain. Med Hypotheses 65 (2005) 530-533
72. Welch K.M. Concepts of migraine headache pathogenesis: insights into mechanisms of chronicity and new drug targets. Neurol Sci 24 Suppl 2 (2003) S149-S153
73. Wolfe F., Smythe H.A., Yunus M.B., Bennett R.M., Bombardier C., Goldenberg D.L., Tugwell P., Campbell S.M., Abeles M., Clark P., et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 33 (1990) 160-172
74. Wolfe F. The relation between tender points and fibromyalgia symptom variables: Evidence that fibromyalgia is not a discrete disorder in the clinic. Ann Rheum Dis 56 (1997) 268-271
75. Wu H., Friedman W.J., and Dreyfus C.F. Differential regulation of neurotrophin expression in basal forebrain astrocytes by neuronal signals. J Neurosci Res 76 (2004) 76-85
76. Yajima Y., Narita M., Usui A., Kaneko C., Miyatake M., Narita M., Yamaguchi T., Tamaki H., Wachi H., Seyama Y., and Suzuki T. Direct evidence for the involvement of brain-derived neurotrophic factor in the development of a neuropathic pain-like state in mice. J Neurochem 93 (2005) 584-594
77. Zur K.B., Oh Y., Waxman S.G., and Black J.A. Differential up-regulation of sodium channel alpha- and beta 1-subunit mRNAs in cultured embryonic DRG neurons following exposure to NGF. Brain Res Mol Brain Res 30 (1995) 97-105