-
1
-
-
39749171410
-
Early events in the pathogenesis of epithelial ovarian cancer
-
Landen CN, Jr, Birrer MJ, Sood AK,. Early events in the pathogenesis of epithelial ovarian cancer. J Clin Oncol 2008; 26: 995-1005.
-
(2008)
J Clin Oncol
, vol.26
, pp. 995-1005
-
-
Landen, Jr.C.N.1
Birrer, M.J.2
Sood, A.K.3
-
3
-
-
58149277751
-
Roles of bioactive sphingolipids in cancer biology and therapeutics
-
Saddoughi SA, Song P, Ogretmen B,. Roles of bioactive sphingolipids in cancer biology and therapeutics. Subcell Biochem 2008; 49: 413-40.
-
(2008)
Subcell Biochem
, vol.49
, pp. 413-440
-
-
Saddoughi, S.A.1
Song, P.2
Ogretmen, B.3
-
4
-
-
77953680582
-
Inhibitors of the sphingosine kinase pathway as potential therapeutics
-
Pitman MR, Pitson SM,. Inhibitors of the sphingosine kinase pathway as potential therapeutics. Curr Cancer Drug Targets 2010; 10: 354-67.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 354-367
-
-
Pitman, M.R.1
Pitson, S.M.2
-
5
-
-
77953671696
-
Activation of sphingosine kinase-1 in cancer: Implications for therapeutic targeting
-
Cuvillier O, Ader I, Bouquerel P, et al. Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting. Curr Mol Pharmacol 2010; 3: 53-65.
-
(2010)
Curr Mol Pharmacol
, vol.3
, pp. 53-65
-
-
Cuvillier, O.1
Ader, I.2
Bouquerel, P.3
-
6
-
-
33845291121
-
Sphingolipids as modulators of cancer cell death: Potential therapeutic targets
-
Segui B, Andrieu-Abadie N, Jaffrezou JP, et al. Sphingolipids as modulators of cancer cell death: potential therapeutic targets. Biochim Biophys Acta 2006; 1758: 2104-20.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 2104-2120
-
-
Segui, B.1
Andrieu-Abadie, N.2
Jaffrezou, J.P.3
-
7
-
-
77953966511
-
Sphingosine 1-phosphate and cancer
-
Pyne NJ, Pyne S,. Sphingosine 1-phosphate and cancer. Nat Rev Cancer 2010; 10: 489-503.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 489-503
-
-
Pyne, N.J.1
Pyne, S.2
-
8
-
-
80155127315
-
Sphingosine kinase inhibitors and cancer: Seeking the golden sword of Hercules
-
Pyne S, Bittman R, Pyne NJ,. Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules. Cancer Res 2011; 71: 6576-82.
-
(2011)
Cancer Res
, vol.71
, pp. 6576-6582
-
-
Pyne, S.1
Bittman, R.2
Pyne, N.J.3
-
10
-
-
33646011572
-
Ki67 immunohistochemistry: A valuable marker in prognostication but with a risk of misclassification: Proliferation subgroups formed based on Ki67 immunoreactivity and standardized mitotic index
-
Jalava P, Kuopio T, Juntti-Patinen L, et al. Ki67 immunohistochemistry: a valuable marker in prognostication but with a risk of misclassification: proliferation subgroups formed based on Ki67 immunoreactivity and standardized mitotic index. Histopathology 2006; 48: 674-82.
-
(2006)
Histopathology
, vol.48
, pp. 674-682
-
-
Jalava, P.1
Kuopio, T.2
Juntti-Patinen, L.3
-
11
-
-
66449134500
-
Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug
-
Guillermet-Guibert J, Davenne L, Pchejetski D, et al. Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug. Mol Cancer Ther 2009; 8: 809-20.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 809-820
-
-
Guillermet-Guibert, J.1
Davenne, L.2
Pchejetski, D.3
-
12
-
-
84876567112
-
Combination of FTY720 with cisplatin exhibits antagonistic effects in ovarian cancer cells: Role of autophagy
-
Zhang N, Dai L, Qi Y, et al. Combination of FTY720 with cisplatin exhibits antagonistic effects in ovarian cancer cells: role of autophagy. Int J Oncol 2013; 42: 2053-9.
-
(2013)
Int J Oncol
, vol.42
, pp. 2053-2059
-
-
Zhang, N.1
Dai, L.2
Qi, Y.3
-
13
-
-
84880291315
-
Evaluating cell lines as tumour models by comparison of genomic profiles
-
Domcke S, Sinha R, Levine DA, et al. Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun 2013; 4: 2126.
-
(2013)
Nat Commun
, vol.4
, pp. 2126
-
-
Domcke, S.1
Sinha, R.2
Levine, D.A.3
-
14
-
-
84893509684
-
Tumor suppressive effects of bromodomain-containing protein 7 (BRD7) in epithelial ovarian carcinoma
-
Park YA, Lee JW, Kim HS, et al. Tumor suppressive effects of bromodomain-containing protein 7 (BRD7) in epithelial ovarian carcinoma. Clin Cancer Res 2014; 20: 565-75.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 565-575
-
-
Park, Y.A.1
Lee, J.W.2
Kim, H.S.3
-
15
-
-
69949135318
-
EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma
-
Lee JW, Han HD, Shahzad MM, et al. EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma. J Natl Cancer Inst 2009; 101: 1193-205.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1193-1205
-
-
Lee, J.W.1
Han, H.D.2
Shahzad, M.M.3
-
16
-
-
80054976661
-
Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer
-
Guan H, Liu L, Cai J, et al. Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer. Mol Endocrinol 2011; 25: 1858-66.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1858-1866
-
-
Guan, H.1
Liu, L.2
Cai, J.3
-
17
-
-
84871970908
-
MiRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways
-
Majid S, Dar AA, Saini S, et al. miRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways. Clin Cancer Res 2013; 19: 73-84.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 73-84
-
-
Majid, S.1
Dar, A.A.2
Saini, S.3
-
18
-
-
33746851955
-
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
-
Thaker PH, Han LY, Kamat AA, et al. Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med 2006; 12: 939-44.
-
(2006)
Nat Med
, vol.12
, pp. 939-944
-
-
Thaker, P.H.1
Han, L.Y.2
Kamat, A.A.3
-
19
-
-
10044265362
-
Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: Potential models
-
Lee CH, Xue H, Sutcliffe M, et al. Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: potential models. Gynecol Oncol 2005; 96: 48-55.
-
(2005)
Gynecol Oncol
, vol.96
, pp. 48-55
-
-
Lee, C.H.1
Xue, H.2
Sutcliffe, M.3
-
20
-
-
80054037863
-
Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer
-
Pchejetski D, Bohler T, Stebbing J, et al. Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer. Nat Rev Urol 2011; 8: 569-678.
-
(2011)
Nat Rev Urol
, vol.8
, pp. 569-678
-
-
Pchejetski, D.1
Bohler, T.2
Stebbing, J.3
-
21
-
-
84896385011
-
Sphingosine kinase 1 and cancer: A systematic review and meta-analysis
-
Zhang Y, Wang Y, Wan Z, et al. Sphingosine kinase 1 and cancer: a systematic review and meta-analysis. PLoS One 2014; 9: e90362.
-
(2014)
PLoS One
, vol.9
, pp. e90362
-
-
Zhang, Y.1
Wang, Y.2
Wan, Z.3
-
22
-
-
77953303657
-
Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells
-
Illuzzi G, Bernacchioni C, Aureli M, et al. Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells. J Biol Chem 2010; 285: 18594-602.
-
(2010)
J Biol Chem
, vol.285
, pp. 18594-18602
-
-
Illuzzi, G.1
Bernacchioni, C.2
Aureli, M.3
-
23
-
-
84864303249
-
Sphingosine kinase-1 inhibition sensitizes curcumin-induced growth inhibition and apoptosis in ovarian cancer cells
-
Yang YL, Ji C, Cheng L, et al. Sphingosine kinase-1 inhibition sensitizes curcumin-induced growth inhibition and apoptosis in ovarian cancer cells. Cancer Sci 2012; 103: 1538-45.
-
(2012)
Cancer Sci
, vol.103
, pp. 1538-1545
-
-
Yang, Y.L.1
Ji, C.2
Cheng, L.3
-
24
-
-
84884992556
-
Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640
-
White MD, Chan L, Antoon JW, et al. Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640. Anticancer Res 2013; 33: 3573-9.
-
(2013)
Anticancer Res
, vol.33
, pp. 3573-3579
-
-
White, M.D.1
Chan, L.2
Antoon, J.W.3
-
25
-
-
0034733556
-
Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform
-
Liu H, Sugiura M, Nava VE, et al. Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform. J Biol Chem 2000; 275: 19513-20.
-
(2000)
J Biol Chem
, vol.275
, pp. 19513-19520
-
-
Liu, H.1
Sugiura, M.2
Nava, V.E.3
-
26
-
-
0142091073
-
Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis
-
Igarashi N, Okada T, Hayashi S, et al. Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis. J Biol Chem 2003; 278: 46832-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 46832-46839
-
-
Igarashi, N.1
Okada, T.2
Hayashi, S.3
-
27
-
-
23844498431
-
Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: Roles of sphingosine kinase isoforms in growth of glioblastoma cell lines
-
Van Brocklyn JR, Jackson CA, Pearl DK, et al. Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines. J Neuropathol Exp Neurol 2005; 64: 695-705.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 695-705
-
-
Van Brocklyn, J.R.1
Jackson, C.A.2
Pearl, D.K.3
-
28
-
-
35948936347
-
Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin
-
Sankala HM, Hait NC, Paugh SW, et al. Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin. Cancer Res 2007; 67: 10466-74.
-
(2007)
Cancer Res
, vol.67
, pp. 10466-10474
-
-
Sankala, H.M.1
Hait, N.C.2
Paugh, S.W.3
-
29
-
-
27744547965
-
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism
-
Maceyka M, Sankala H, Hait NC, et al. SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. J Biol Chem 2005; 280: 37118-29.
-
(2005)
J Biol Chem
, vol.280
, pp. 37118-37129
-
-
Maceyka, M.1
Sankala, H.2
Hait, N.C.3
-
30
-
-
0028372227
-
Fungal metabolites, Part 11: A potent immunosuppressive activity found in Isaria sinclairii metabolite
-
Fujita T, Inoue K, Yamamoto S, et al. Fungal metabolites, Part 11: a potent immunosuppressive activity found in Isaria sinclairii metabolite. J Antibiot (Tokyo) 1994; 47: 208-15.
-
(1994)
J Antibiot (Tokyo)
, vol.47
, pp. 208-215
-
-
Fujita, T.1
Inoue, K.2
Yamamoto, S.3
-
31
-
-
46949104885
-
"inside-out" signaling of sphingosine-1-phosphate: Therapeutic targets
-
Takabe K, Paugh SW, Milstien S, et al. "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol Rev 2008; 60: 181-95.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 181-195
-
-
Takabe, K.1
Paugh, S.W.2
Milstien, S.3
-
32
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
Kappos L, Antel J, Comi G, et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med 2006; 355: 1124-40.
-
(2006)
N Engl J Med
, vol.355
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
-
33
-
-
67449098149
-
Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation
-
Nemoto S, Nakamura M, Osawa Y, et al. Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation. J Biol Chem 2009; 284: 10422-32.
-
(2009)
J Biol Chem
, vol.284
, pp. 10422-10432
-
-
Nemoto, S.1
Nakamura, M.2
Osawa, Y.3
-
34
-
-
62549143484
-
Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells
-
Schnitzer SE, Weigert A, Zhou J, et al. Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells. Mol Cancer Res 2009; 7: 393-401.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 393-401
-
-
Schnitzer, S.E.1
Weigert, A.2
Zhou, J.3
-
36
-
-
78649305851
-
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy
-
Zhang N, Qi Y, Wadham C, et al. FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy. Autophagy 2010; 6: 1157-67.
-
(2010)
Autophagy
, vol.6
, pp. 1157-1167
-
-
Zhang, N.1
Qi, Y.2
Wadham, C.3
-
37
-
-
84859149451
-
FTY720-induced blockage of autophagy enhances anticancer efficacy of milatuzumab in mantle cell lymphoma: Is FTY720 the next autophagy-blocking agent in lymphoma treatment?
-
Alinari L, Baiocchi RA, Praetorius-Ibba M,. FTY720-induced blockage of autophagy enhances anticancer efficacy of milatuzumab in mantle cell lymphoma: is FTY720 the next autophagy-blocking agent in lymphoma treatment? Autophagy 2012; 8: 416-17.
-
(2012)
Autophagy
, vol.8
, pp. 416-417
-
-
Alinari, L.1
Baiocchi, R.A.2
Praetorius-Ibba, M.3
|