Lrp1/LDL Receptor Play Critical Roles in Mannose 6-Phosphate-Independent Lysosomal Enzyme Targeting

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Volumn 16, Issue 7, 2015, Pages 743-759

  Markmann, Sandra ^a   Thelen, Melanie ^b   Cornils, Kerstin ^a   Schweizer, Michaela ^a   Brocke Ahmadinejad, Nahal ^b   Willnow, Thomas ^c   Heeren, Joerg ^a   Gieselmann, Volkmar ^b   Braulke, Thomas ^a   Kollmann, Katrin ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Low density lipoprotein related receptor; Lysosomal storage disorder; Lysosomal targeting; Mannose 6 phosphate; Receptor mediated endocytosis; Sortilin

Indexed keywords

CATHEPSIN B; CATHEPSIN D; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LYSOSOME ENZYME; MANNOSE 6 PHOSPHATE; SORTILIN; STABLE ISOTOPE; CATHEPSIN; LRP1 PROTEIN, MOUSE; MANNOSE PHOSPHATE; MANNOSE-6-PHOSPHATE; TUMOR SUPPRESSOR PROTEIN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; ENDOCYTOSIS; ENDOSOME; ENZYME REPLACEMENT; FIBROBLAST; ISOTOPE LABELING; LYSOSOME; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TARGETING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; GENETICS; METABOLISM; PROTEIN TRANSPORT;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CATHEPSINS; CELLS, CULTURED; FIBROBLASTS; LYSOSOMES; MANNOSEPHOSPHATES; MICE; MICE, INBRED C57BL; PROTEIN TRANSPORT; RECEPTORS, LDL; TUMOR SUPPRESSOR PROTEINS;

EID: 84930378454     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12284     Document Type: Article

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