Ribosomal initiation complex-driven changes in the stability and dynamics of initiation factor 2 regulate the fidelity of translation initiation

Journal of Molecular Biology

Volumn 427, Issue 9, 2015, Pages 1819-1834

  Wang, Jiangning ^a   Caban, Kelvin ^a   Gonzalez, Ruben L ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

30S IC; binding kinetics; conformational dynamics; smFRET; translation initiation

Indexed keywords

GUANOSINE TRIPHOSPHATE; INITIATION FACTOR 2; MESSENGER RNA; METHIONINE TRANSFER RNA;

CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETICS; METABOLISM; PROTEIN SYNTHESIS; RIBOSOME; SMALL RIBOSOMAL SUBUNIT;

ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; GUANOSINE TRIPHOSPHATE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROKARYOTIC INITIATION FACTOR-2; PROTEIN BIOSYNTHESIS; RIBOSOME SUBUNITS, SMALL, BACTERIAL; RIBOSOMES; RNA, MESSENGER; RNA, TRANSFER, MET;

EID: 84930374787     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.12.025     Document Type: Article

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