Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Cocita, Clément ^a,b   Guiton, Rachel ^a,b,c   Bessou, Gilles ^a,b   Chasson, Lionel ^a,b   Boyron, Marilyn ^a,b   Crozat, Karine ^a,b   Dalod, Marc ^a,b  

^a CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^b INSERM   (France)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON TYPE 1; INTERLEUKIN 12; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; IFNAR1 PROTEIN, MOUSE; INTERFERON; KLRA8 PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY A; TLR9 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNE RESPONSE; LEUKOCYTE; MICROARRAY ANALYSIS; MORBIDITY; MORTALITY; MOUSE; NATURAL KILLER CELL; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; VIRUS LOAD; AGONISTS; ANIMAL; BAGG ALBINO MOUSE; BLOOD; DEFICIENCY; DENDRITIC CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GERMFREE ANIMAL; HERPES VIRUS INFECTION; HOST PATHOGEN INTERACTION; IMMUNE DEFICIENCY; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; METABOLISM; MUROMEGALOVIRUS; MUTANT MOUSE STRAIN; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPLEEN; VIROLOGY;

CYTOMEGALOVIRUS; HERPESVIRIDAE; MAIZE CHLOROTIC MOTTLE VIRUS; MUS;

ANIMALS; DENDRITIC CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HERPESVIRIDAE INFECTIONS; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; IMMUNOLOGIC DEFICIENCY SYNDROMES; INTERFERON TYPE I; INTERLEUKIN-12; KILLER CELLS, NATURAL; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MUROMEGALOVIRUS; MYELOID DIFFERENTIATION FACTOR 88; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY A; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS; SPLEEN; TOLL-LIKE RECEPTOR 9;

EID: 84930339666     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004897     Document Type: Article

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