Rapid emergence of escape mutants following infection with murine cytomegalovirus in immunodeficient mice

Clinical Immunology

Volumn 115, Issue 1 SPEC. ISS., 2005, Pages 61-69

  French, Anthony R ^a   Pingel, Jeanette T ^a   Kim, Sungjin ^a   Yang, Liping ^a   Yokoyama, Wayne M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Innate immunity; m157; MCMV; NK cells; Viral escape mutants

Indexed keywords

CONFERENCE PAPER; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; GENE MUTATION; HUMAN; IMMUNE DEFICIENCY; INNATE IMMUNITY; MOLECULAR RECOGNITION; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 18144384424     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clim.2005.02.008     Document Type: Conference Paper

References (55)

1. C.A. Biron Initial and innate responses to viral infections-pattern setting in immunity or disease Curr. Opin. Microbiol. 2 1999 374 381
2. A.R. French, and W.M. Yokoyama Natural killer cells and viral infections Curr. Opin. Immunol. 15 2003 45 51
3. C.A. Biron, K.S. Byron, and J.L. Sullivan Severe herpesvirus infections in an adolescent without natural killer cells N. Engl. J. Med. 320 1989 1731 1735
4. J.S. Orange Human natural killer cell deficiencies and susceptibility to infection Microbes Infect. 4 2002 1545 1558
5. J.F. Bukowski, B.A. Woda, S. Habu, K. Okumura, and R.M. Welsh Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo J. Immunol. 131 1983 1531 1538
6. C.A. Janeway Jr. How the immune system works to protect the host from infection: a personal view Proc. Natl. Acad. Sci. U. S. A. 98 2001 7461 7468
7. P. Parham Innate immunity: the unsung heroes Nature 423 2003 20
8. M.G. Brown, A.O. Dokun, and J.W. Heusel Vital involvement of a natural killer cell activation receptor in resistance to viral infection Science 292 2001 934 937
9. T.P. Salazar-Mather, C.A. Lewis, and C.A. Biron Type I interferons regulate inflammatory cell trafficking and macrophage inflammatory protein 1alpha delivery to the liver J. Clin. Invest. 110 2002 321 330
10. A.A. Scalzo, N.A. Fitzgerald, A. Simmons, A.B. La Vista, and G.R. Shellam Cmv-1, a genetic locus that controls murine cytomegalovirus replication in the spleen J. Exp. Med. 171 1990 1469 1483
11. K.A. Daniels, G. Devora, W.C. Lai, C.L. O'Donnell, M. Bennett, and R.M. Welsh Murine cytomegalovirus is regulated by a discrete subset of natural killer cells reactive with monoclonal antibody to ly49h J. Exp. Med. 194 2001 29 44
12. S.H. Lee, S. Girard, and D. Macina Susceptibility to mouse cytomegalovirus is associated with deletion of an activating natural killer cell receptor of the C-type lectin superfamily Nat. Genet. 28 2001 42 45
13. S.H. Lee, A. Zafer, and Y. de Repentigny Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice J. Exp. Med. 197 2003 515 526
14. H. Arase, E.S. Mocarski, A.E. Campbell, A.B. Hill, and L.L. Lanier Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors Science 296 2002 1323 1326
15. H.R. Smith, J.W. Heusel, and I.K. Mehta Recognition of a virus-encoded ligand by a natural killer cell activation receptor Proc. Natl. Acad. Sci. U. S. A. 99 2002 8826 8831
16. D. Tortorella, B.E. Gewurz, M.H. Furman, D.J. Schust, and H.L. Ploegh Viral subversion of the immune system Annu. Rev. Immunol. 18 2000 861 926
17. M. Lucas, U. Karrer, A. Lucas, and P. Klenerman Viral escape mechanisms-escapology taught by viruses Int. J. Exp. Pathol. 82 2001 269 286
18. J.S. Orange, M.S. Fassett, L.A. Koopman, J.E. Boyson, and J.L. Strominger Viral evasion of natural killer cells Nat. Immunol. 3 2002 1006 1012
19. A.A. Scalzo Successful control of viruses by NK cells-A balance of opposing forces? Trends Microbiol. 10 2002 470 474
20. P.J. Goulder, C. Brander, and Y. Tang Evolution and transmission of stable CTL escape mutations in HIV infection Nature 412 2001 334 338
21. Y.S. Hahn Subversion of immune responses by hepatitis C virus: immunomodulatory strategies beyond evasion? Curr. Opin. Immunol. 15 2003 443 449
22. E. Domingo, L. Menendez-Arias, and M.E. Quinones-Mateu Viral quasispecies and the problem of vaccine-escape and drug-resistant mutants Prog. Drug Res. 48 1997 99 128
23. P. Poignard, R. Sabbe, and G.R. Picchio Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo Immunity 10 1999 431 438
24. S.J. Schrag, P.A. Rota, and W.J. Bellini Spontaneous mutation rate of measles virus: direct estimation based on mutations conferring monoclonal antibody resistance J. Virol. 73 1999 51 54
25. A. Ciurea, P. Klenerman, and L. Hunziker Viral persistence in vivo through selection of neutralizing antibody-escape variants Proc. Natl. Acad. Sci. U. S. A. 97 2000 2749 2754
26. L. Hunziker, A. Ciurea, M. Recher, H. Hengartner, and R.M. Zinkernagel Public versus personal serotypes of a viral quasispecies Proc. Natl. Acad. Sci. U. S. A. 100 2003 6015 6020
27. A. Weiner, A.L. Erickson, and J. Kansopon Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant Proc. Natl. Acad. Sci. U. S. A. 92 1995 2755 2759
28. K.M. Chang, B. Rehermann, and J.G. McHutchison Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus J. Clin. Invest. 100 1997 2376 2385
29. A.L. Erickson, Y. Kimura, and S. Igarashi The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes Immunity 15 2001 883 895
30. A. Kaur, L. Alexander, and S.I. Staprans Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection Eur. J. Immunol. 31 2001 3207 3217
31. W.D. Rawlinson, H.E. Farrell, and B.G. Barrell Analysis of the complete DNA sequence of murine cytomegalovirus J. Virol. 70 1996 8833 8849
32. E.S. Mocarski Jr. Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion Trends Microbiol. 10 2002 332 339
33. M.J. Reddehase Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance Nat. Rev., Immunol. 2 2002 831 844
34. M. Lodoen, K. Ogasawara, and J.A. Hamerman NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules J. Exp. Med. 197 2003 1245 1253
35. M.B. Lodoen, G. Abenes, S. Umamoto, J.P. Houchins, F. Liu, and L.L. Lanier The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions J. Exp. Med. 200 2004 1075 1081
36. H.E. Farrell, H. Vally, and D.M. Lynch Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo Nature 386 1997 510 514
37. E. Cretney, M.A. Degli-Esposti, and E.H. Densley m144, a murine cytomegalovirus-encoded major histocompatibility complex class I homologue, confers tumor resistance to natural killer cell-mediated rejection J. Exp. Med. 190 1999 435 444
38. J.W. Drake A constant rate of spontaneous mutation in DNA-based microbes Proc. Natl. Acad. Sci. U. S. A. 88 1991 7160 7164
39. J.W. Drake The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes Ann. N. Y. Acad. Sci. 870 1999 100 107
40. J.W. Drake Rates of spontaneous mutation among RNA viruses Proc. Natl. Acad. Sci. U. S. A. 90 1993 4171 4175
41. J.W. Drake, B. Charlesworth, D. Charlesworth, and J.F. Crow Rates of spontaneous mutation Genetics 148 1998 1667 1686
42. A. Lopez-Bueno, M.G. Mateu, and J.M. Almendral High mutant frequency in populations of a DNA virus allows evasion from antibody therapy in an immunodeficient host J. Virol. 77 2003 2701 2708
43. A.R. French, J.T. Pingel, and M. Wagner Escape of mutant double-stranded DNA virus from innate immune control Immunity 20 2004 747 756
44. I. Bubic, M. Wagner, and A. Krmpotic Gain of virulence caused by loss of a gene in murine cytomegalovirus J. Virol. 78 2004 7536 7544
45. A.O. Dokun, S. Kim, H.R. Smith, H.S. Kang, D.T. Chu, and W.M. Yokoyama Specific and nonspecific NK cell activation during virus infection Nat. Immunol. 2 2001 951 956
46. H.R. Smith, H.H. Chuang, L.L. Wang, M. Salcedo, J.W. Heusel, and W.M. Yokoyama Nonstochastic coexpression of activation receptors on murine natural killer cells J. Exp. Med. 191 2000 1341 1354
47. A.H. Idris, H.R.C. Smith, L.H. Mason, J.H. Ortaldo, A.A. Scalzo, and W.M. Yokoyama The natural killer cell complex genetic locus, Chok, encodes Ly49D, a target recognition receptor that activates natural killing Proc. Natl. Acad. Sci. U. S. A. 96 1999 6330 6335
48. A.A. Scalzo, P.A. Lyons, N.A. Fitzgerald, C.A. Forbes, and G.R. Shellam The BALB.B6-Cmv1r mouse: a strain congenic for Cmv1 and the NK gene complex Immunogenetics 41 1995 148 151
49. R. Thale, U. Szepan, H. Hengel, G. Geginat, P. Lucin, and U.H. Koszinowski Identification of the mouse cytomegalovirus genomic region affecting major histocompatibility complex class I molecule transport J. Virol. 69 1995 6098 6105
50. A. Ciurea, L. Hunziker, M.M. Martinic, A. Oxenius, H. Hengartner, and R.M. Zinkernagel CD4+ T-cell-epitope escape mutant virus selected in vivo Nat. Med. 7 2001 795 800
51. V. DeFilippis, and L. Villareal Virus evolution D.M. Knipe P.M. Howley Fields virology 2001 Lippincott Williams and Wilkins Philadelphia 353 370
52. V. Voigt, C.A. Forbes, and J.N. Tonkin Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells Proc. Natl. Acad. Sci. U. S. A. 100 2003 13483 13488
53. A.S. Fauci, and H.C. Lane Human immunodeficiency virus (HIV) disease: AIDS and related disorders E. Braunwald A.S. Fauci D.L. Kasper S.L. Hauser D.L. Longo J.L. Jameson Harrison's principles of internal medicine 15th ed. 2001 McGraw-Hill New York 1852 1913
54. J.A. Fishman, and R.H. Rubin Infection in organ-transplant recipients N. Engl. J. Med. 338 1998 1741 1751
55. K. Schwarz, L. Notarangelo, E. Spanopoulou, P. Vezzoni, and A. Villa Recombination defects O. HD C. Smith P. JM Primary immunodeficiency diseases: a molecular and genetic approach 1999 Oxford University Press New York 155 166