메뉴 건너뛰기




Volumn 37, Issue 4, 2015, Pages 699-703

The Puerarin improves renal function in STZ-induced diabetic rats by attenuating eNOS expression

Author keywords

Diabetic nephropathy; ENOS; Puerarin; Renal function; Ultrastructural changes

Indexed keywords

CREATININE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; PUERARIN; ISOFLAVONE DERIVATIVE; STREPTOZOCIN;

EID: 84930324329     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2015.1011500     Document Type: Article
Times cited : (27)

References (33)
  • 1
    • 84880174930 scopus 로고    scopus 로고
    • Chronic vascular complications in diabetes
    • Jia W, Xu A, Chen A, Wu J, Ye J. Chronic vascular complications in diabetes. J Diabetes Res. 2013;2013:858746.
    • (2013) J Diabetes Res. , vol.2013 , pp. 858746
    • Jia, W.1    Xu, A.2    Chen, A.3    Wu, J.4    Ye, J.5
  • 2
    • 84899019637 scopus 로고    scopus 로고
    • Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes
    • Wang F, Huang B, Li J, Liu L, Wang N. Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes. Ren Fail. 2014;36(4):552-6.
    • (2014) Ren Fail. , vol.36 , Issue.4 , pp. 552-556
    • Wang, F.1    Huang, B.2    Li, J.3    Liu, L.4    Wang, N.5
  • 3
    • 84861159160 scopus 로고    scopus 로고
    • Telmisartan in the management of diabetic nephropathy: A contemporary view
    • Balakumar P, Bishnoi HK, Mahadevan N. Telmisartan in the management of diabetic nephropathy: A contemporary view. Curr Diabetes Rev. 2012;8(3):183-90.
    • (2012) Curr Diabetes Rev. , vol.8 , Issue.3 , pp. 183-190
    • Balakumar, P.1    Bishnoi, H.K.2    Mahadevan, N.3
  • 4
    • 80053184594 scopus 로고    scopus 로고
    • End-stage renal disease due to diabetes in racial/ethnic minorities and disadvantaged populations
    • Lopes AA. End-stage renal disease due to diabetes in racial/ethnic minorities and disadvantaged populations. Ethn Dis. 2009; 19(1 Suppl 1):S1-47-S1-51.
    • (2009) Ethn Dis. , vol.19 , Issue.1
    • Lopes, A.A.1
  • 7
    • 84869220435 scopus 로고    scopus 로고
    • Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice
    • Cheng H, Wang H, Fan X, Paueksakon P, Harris RC. Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Kidney Int. 2012; 82(11):1176-1183.
    • (2012) Kidney Int. , vol.82 , Issue.11 , pp. 1176-1183
    • Cheng, H.1    Wang, H.2    Fan, X.3    Paueksakon, P.4    Harris, R.C.5
  • 8
    • 84908597007 scopus 로고    scopus 로고
    • A meta-Analysis on the relationship of eNOS 4b/a polymorphism and diabetic nephropathy susceptibility
    • Zeng R, Duan L, Sun L, et al. A meta-Analysis on the relationship of eNOS 4b/a polymorphism and diabetic nephropathy susceptibility. Ren Fail. 2014;36(10):1520-1535.
    • (2014) Ren Fail. , vol.36 , Issue.10 , pp. 1520-1535
    • Zeng, R.1    Duan, L.2    Sun, L.3
  • 9
    • 79951603597 scopus 로고    scopus 로고
    • Complete disruption of all nitric oxide synthase genes causes markedly accelerated renal lesion formation following unilateral ureteral obstruction in mice in vivo
    • Morisada N, Nomura M, Nishii H, et al. Complete disruption of all nitric oxide synthase genes causes markedly accelerated renal lesion formation following unilateral ureteral obstruction in mice in vivo. J Pharmacol Sci. 2010;114(4):379-389.
    • (2010) J Pharmacol Sci. , vol.114 , Issue.4 , pp. 379-389
    • Morisada, N.1    Nomura, M.2    Nishii, H.3
  • 10
    • 79959777296 scopus 로고    scopus 로고
    • Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats
    • Arya A, Yadav HN, Sharma PL. Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats. Mol Cell Biochem. 2011;354(1-2):57-66.
    • (2011) Mol Cell Biochem. , vol.354 , Issue.1-2 , pp. 57-66
    • Arya, A.1    Yadav, H.N.2    Sharma, P.L.3
  • 11
    • 84892406156 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene polymorphisms and risk of diabetic nephropathy: A systematic review and meta-Analysis
    • Dellamea BS, Pinto LC, Leitao CB, Santos KG, Canani LH. Endothelial nitric oxide synthase gene polymorphisms and risk of diabetic nephropathy: A systematic review and meta-Analysis. BMC Med Genet. 2014;15:9.
    • (2014) BMC Med Genet. , vol.15 , pp. 9
    • Dellamea, B.S.1    Pinto, L.C.2    Leitao, C.B.3    Santos, K.G.4    Canani, L.H.5
  • 12
    • 84884203817 scopus 로고    scopus 로고
    • Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-beta1/Smad signaling pathway, thereby leading to anti-fibrotic effect
    • Xu L, Zheng N, He Q, Li R, Zhang K, Liang T. Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-beta1/Smad signaling pathway, thereby leading to anti-fibrotic effect. Phytomedicine. 2013; 20(13):1172-1179.
    • (2013) Phytomedicine. , vol.20 , Issue.13 , pp. 1172-1179
    • Xu, L.1    Zheng, N.2    He, Q.3    Li, R.4    Zhang, K.5    Liang, T.6
  • 13
    • 84904329150 scopus 로고    scopus 로고
    • Puerarin ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney through ERK/Nrf2/ARE pathway
    • Ma JQ, Ding J, Xiao ZH, Liu CM. Puerarin ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney through ERK/Nrf2/ARE pathway. Food Chem Toxicol. 2014;71:264-271.
    • (2014) Food Chem Toxicol. , vol.71 , pp. 264-271
    • Ma, J.Q.1    Ding, J.2    Xiao, Z.H.3    Liu, C.M.4
  • 14
    • 84899519690 scopus 로고    scopus 로고
    • Effects of Puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-beta1/Smad2 pathway
    • She S, Liu W, Li T, Hong Y. Effects of Puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-beta1/Smad2 pathway. Food Funct. 2014;5(5):944-950.
    • (2014) Food Funct. , vol.5 , Issue.5 , pp. 944-950
    • She, S.1    Liu, W.2    Li, T.3    Hong, Y.4
  • 15
    • 84898652796 scopus 로고    scopus 로고
    • Puerarin attenuated early diabetic kidney injury through down-regulation of matrix metalloproteinase 9 in streptozotocin-induced diabetic rats
    • Zhong Y, Zhang X, Cai X, Wang K, Chen Y, Deng Y. Puerarin attenuated early diabetic kidney injury through down-regulation of matrix metalloproteinase 9 in streptozotocin-induced diabetic rats. PLoS One. 2014;9(1):e85690.
    • (2014) PLoS One. , vol.9 , Issue.1 , pp. e85690
    • Zhong, Y.1    Zhang, X.2    Cai, X.3    Wang, K.4    Chen, Y.5    Deng, Y.6
  • 16
    • 84872299083 scopus 로고    scopus 로고
    • Protective effects of Puerarin on experimental chronic lead nephrotoxicity in immature female rats
    • Wang L, Lin S, Li Z, Yang D, Wang Z. Protective effects of Puerarin on experimental chronic lead nephrotoxicity in immature female rats. Hum Exp Toxicol. 2013;32(2):172-185.
    • (2013) Hum Exp Toxicol. , vol.32 , Issue.2 , pp. 172-185
    • Wang, L.1    Lin, S.2    Li, Z.3    Yang, D.4    Wang, Z.5
  • 17
    • 84872299083 scopus 로고    scopus 로고
    • Protective effects of Puerarin on experimental chronic lead nephrotoxicity in immature female rats
    • Wang L, Lin S, Li Z, Yang D, Wang Z. Protective effects of Puerarin on experimental chronic lead nephrotoxicity in immature female rats. Hum Exp Toxicol. 2013;32(2):172-185.
    • (2013) Hum Exp Toxicol. , vol.32 , Issue.2 , pp. 172-185
    • Wang, L.1    Lin, S.2    Li, Z.3    Yang, D.4    Wang, Z.5
  • 18
    • 67650854594 scopus 로고    scopus 로고
    • Effect of Puerarin on the expression of extracellular matrix in rats with streptozotocin-induced diabetic nephropathy
    • Li Q, Xiao Y, Gong H, et al. Effect of Puerarin on the expression of extracellular matrix in rats with streptozotocin-induced diabetic nephropathy. Natl Med J India. 2009;22(1):9-12.
    • (2009) Natl Med J India. , vol.22 , Issue.1 , pp. 9-12
    • Li, Q.1    Xiao, Y.2    Gong, H.3
  • 19
    • 84904329150 scopus 로고    scopus 로고
    • Puerarin ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney through ERK/Nrf2/ARE pathway
    • Ma JQ, Ding J, Xiao ZH, Liu CM. Puerarin ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney through ERK/Nrf2/ARE pathway. Food Chem Toxicol. 2014;71:264-271.
    • (2014) Food Chem Toxicol. , vol.71 , pp. 264-271
    • Ma, J.Q.1    Ding, J.2    Xiao, Z.H.3    Liu, C.M.4
  • 20
    • 84884272553 scopus 로고    scopus 로고
    • Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes
    • Advani A, Connelly KA, Advani SL, et al. Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes. Biomed Res Int. 2013;2013:201475.
    • (2013) Biomed Res Int. , vol.2013 , pp. 201475
    • Advani, A.1    Connelly, K.A.2    Advani, S.L.3
  • 21
    • 84913537510 scopus 로고    scopus 로고
    • Are nitric oxide-mediated protein modifications of functional significance in diabetic heart? Ye's,-NO', wh'y-NO't?
    • Jayakumari NR, Reghuvaran AC, Rajendran RS, et al. Are nitric oxide-mediated protein modifications of functional significance in diabetic heart?. ye's,-NO', wh'y-NO't?. Nitric Oxide. 2014; 43:35-44.
    • (2014) Nitric Oxide. , vol.43 , pp. 35-44
    • Jayakumari, N.R.1    Reghuvaran, A.C.2    Rajendran, R.S.3
  • 22
    • 3142564598 scopus 로고    scopus 로고
    • Role of nitric oxide in diabetic nephropathy
    • Prabhakar SS. Role of nitric oxide in diabetic nephropathy. Semin Nephrol. 2004;24(4):333-344.
    • (2004) Semin Nephrol. , vol.24 , Issue.4 , pp. 333-344
    • Prabhakar, S.S.1
  • 23
    • 46749151715 scopus 로고    scopus 로고
    • Effects of N-hexacosanol on nitric oxide synthase system in diabetic rat nephropathy
    • Okada S, Saito M, Kazuyama E, et al. Effects of N-hexacosanol on nitric oxide synthase system in diabetic rat nephropathy. Mol Cell Biochem. 2008;315(1-2):169-177.
    • (2008) Mol Cell Biochem. , vol.315 , Issue.1-2 , pp. 169-177
    • Okada, S.1    Saito, M.2    Kazuyama, E.3
  • 24
    • 58549087946 scopus 로고    scopus 로고
    • Glomerular endothelial NOS (eNOS) expression in type 2 diabetic patients with nephropathy
    • 3037; author reply
    • Komers R, Anderson S. Glomerular endothelial NOS (eNOS) expression in type 2 diabetic patients with nephropathy. Nephrol Dial Transplant. 2008;23(9):3037; author reply 3037-3038.
    • (2008) Nephrol Dial Transplant. , vol.23 , Issue.9 , pp. 3037-3038
    • Komers, R.1    Anderson, S.2
  • 25
    • 84860739072 scopus 로고    scopus 로고
    • Puerarin inhibits caspase-3 expression in osteoblasts of diabetic rats
    • Liang J, Chen H, Pan W, Xu C. Puerarin inhibits caspase-3 expression in osteoblasts of diabetic rats. Mol Med Rep. 2012; 5(6):1419-1422.
    • (2012) Mol Med Rep. , vol.5 , Issue.6 , pp. 1419-1422
    • Liang, J.1    Chen, H.2    Pan, W.3    Xu, C.4
  • 26
    • 84893018584 scopus 로고    scopus 로고
    • Comparison between the efficacies of curcumin and Puerarin in C57BL/6 mice with steatohepatitis induced by a methionine-And choline-deficient diet
    • Wang Y, Li J, Zhuge L, Su D, Yang M, Tao S. Comparison between the efficacies of curcumin and Puerarin in C57BL/6 mice with steatohepatitis induced by a methionine-And choline-deficient diet. Exp Ther Med. 2014;7(3):663-668.
    • (2014) Exp Ther Med. , vol.7 , Issue.3 , pp. 663-668
    • Wang, Y.1    Li, J.2    Zhuge, L.3    Su, D.4    Yang, M.5    Tao, S.6
  • 27
    • 74149093839 scopus 로고    scopus 로고
    • Puerarin attenuates high-glucoseand diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling
    • Zhu LH, Wang L, Wang D, et al. Puerarin attenuates high-glucoseand diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling. Free Radic Biol Med. 2009;48(4):471-482.
    • (2009) Free Radic Biol Med. , vol.48 , Issue.4 , pp. 471-482
    • Zhu, L.H.1    Wang, L.2    Wang, D.3
  • 28
    • 84898652796 scopus 로고    scopus 로고
    • Puerarin attenuated early diabetic kidney injury through down-regulation of matrix metalloproteinase 9 in streptozotocin-induced diabetic rats
    • Zhong Y, Zhang X, Cai X, Wang K, Chen Y, Deng Y. Puerarin attenuated early diabetic kidney injury through down-regulation of matrix metalloproteinase 9 in streptozotocin-induced diabetic rats. PLoS One. 2014;9(1):e85690.
    • (2014) PLoS One. , vol.9 , Issue.1 , pp. e85690
    • Zhong, Y.1    Zhang, X.2    Cai, X.3    Wang, K.4    Chen, Y.5    Deng, Y.6
  • 29
    • 84865063532 scopus 로고    scopus 로고
    • Puerarin prevents isoprenalineinduced myocardial fibrosis in mice by reduction of myocardial TGF-beta1 expression
    • Chen R, Xue J, Xie M. Puerarin prevents isoprenalineinduced myocardial fibrosis in mice by reduction of myocardial TGF-beta1 expression. J Nutr Biochem. 2011; 23(9):1080-1085.
    • (2011) J Nutr Biochem. , vol.23 , Issue.9 , pp. 1080-1085
    • Chen, R.1    Xue, J.2    Xie, M.3
  • 30
    • 34548681835 scopus 로고    scopus 로고
    • Protective roles of Puerarin and Danshensu on acute ischemic myocardial injury in rats
    • Wu L, Qiao H, Li Y, Li L. Protective roles of Puerarin and Danshensu on acute ischemic myocardial injury in rats. Phytomedicine. 2007;14(10):652-658.
    • (2007) Phytomedicine. , vol.14 , Issue.10 , pp. 652-658
    • Wu, L.1    Qiao, H.2    Li, Y.3    Li, L.4
  • 32
    • 84921438141 scopus 로고    scopus 로고
    • Protective effects of Puerarin against Ass40-induced vascular dysfunction in zebrafish and human endothelial cells
    • Lu XL, Liu JX, Wu Q, et al. Protective effects of Puerarin against Ass40-induced vascular dysfunction in zebrafish and human endothelial cells. Eur J Pharmacol. 2014;732:76-85.
    • (2014) Eur J Pharmacol. , vol.732 , pp. 76-85
    • Lu, X.L.1    Liu, J.X.2    Wu, Q.3
  • 33
    • 33646449792 scopus 로고    scopus 로고
    • Puerarin induces angiogenesis in myocardium of rat with myocardial infarction
    • Zhang S, Chen S, Shen Y, et al. Puerarin induces angiogenesis in myocardium of rat with myocardial infarction. Biol Pharm Bull. 2006;29(5):945-950.
    • (2006) Biol Pharm Bull. , vol.29 , Issue.5 , pp. 945-950
    • Zhang, S.1    Chen, S.2    Shen, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.