Design of New Ligands for the Palladium-Catalyzed Arylation of α-Branched Secondary Amines

Angewandte Chemie - International Edition

Volumn 54, Issue 28, 2015, Pages 8259-8262

  Park, Nathaniel H ^a   Vinogradova, Ekaterina V ^a   Surry, David S ^a   Buchwald, Stephen L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

amination; cross coupling; ligand design; palladium; synthetic methods

Indexed keywords

AMINATION; AMINES; AROMATIC COMPOUNDS; CATALYSIS; LIGANDS; PALLADIUM;

CROSS COUPLING REACTIONS; CROSS-COUPLINGS; LIGAND DESIGN; PALLADIUM-CATALYZED ARYLATION; SECONDARY AMINES; SIDE REACTIONS; SYNTHETIC METHODS; TERTIARY AMINE;

CHEMICAL REACTIONS;

AMINE; LIGAND; PALLADIUM;

AMINATION; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY;

AMINATION; AMINES; CATALYSIS; LIGANDS; MOLECULAR STRUCTURE; PALLADIUM;

EID: 84930321922     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201502626     Document Type: Article

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65. When P7 was used, the yields of 3 a, 3 b and 3 c were 5 %, 60 %, and 70 % respectively, see the Supporting Information.
66. See the Supporting Information.