Synthesis of 2-substituted 1-benzyl-2,3,4,5-tetrahydro-1-benzazepines by palladium catalysis. Observation of a competitive β-hydride elimination pathway

Tetrahedron Letters

Volumn 44, Issue 18, 2003, Pages 3675-3678

  Qadir, Maryiam ^a   Priestley, Rachael E ^a   Rising, Thomas W D F ^a   Gelbrich, Thomas ^b   Coles, Simon J ^b   Hursthouse, Michael B ^b   Sheldrake, Peter W ^c   Whittall, Neil ^c   Hii, K K ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Benzazepines; Heterocycles; Palladium catalysis; hydride elimination

Indexed keywords

1 BENZYL 2,3,4,5 TETRAHYDRO 1 BENZAZEPINE; BENZAZEPINE DERIVATIVE; BENZENE DERIVATIVE; PALLADIUM; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BOND; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

EID: 0037471462     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(03)00676-2     Document Type: Article

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