Protective effects of melatonin-loaded lipid-core nanocapsules on paraquat-induced cytotoxicity and genotoxicity in a pulmonary cell line

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 784-785, Issue , 2015, Pages 1-9

  Charão, Mariele F ^a   Baierle, Marília ^a   Gauer, Bruna ^a   Goethel, Gabriela ^a   Fracasso, Rafael ^a   Paese, Karina ^a   Brucker, Natália ^a   Moro, Angela M ^a   Bubols, Guilherme B ^a   Dias, Bruna B ^a   Matte, Ursula S ^b   Guterres, Silvia S ^a   Pohlmann, Adriana R ^a   Garcia, Solange C ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

A549 cell line; Comet assay; DNA damage; Melatonin loaded lipid core nanocapsules; Nanotechnology; Paraquat

Indexed keywords

ANTIOXIDANT; LIPID; MELATONIN; NANOCAPSULE; PARAQUAT; RHODAMINE B; CULTURE MEDIUM;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; COLUMN CHROMATOGRAPHY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG FORMULATION; ELECTROPHORETIC MOBILITY; FLUORESCENCE; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; LASER DIFFRACTION; LUNG ALVEOLUS EPITHELIUM CELL; NUCLEAR MAGNETIC RESONANCE; PH MEASUREMENT; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; ZETA POTENTIAL; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECTS; LUNG ALVEOLUS; METABOLISM; PARTICLE SIZE; TUMOR CELL LINE;

ANTIOXIDANTS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CULTURE MEDIA; DNA DAMAGE; HUMANS; MELATONIN; NANOCAPSULES; PARAQUAT; PARTICLE SIZE; PULMONARY ALVEOLI;

EID: 84930278448     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2015.04.006     Document Type: Article

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