메뉴 건너뛰기




Volumn 5, Issue 4, 2014, Pages 1050-1063

Long non-coding RNA NEAT1 associates with SRp40 to temporally regulate PPARγ2 splicing during adipogenesis in 3T3-L1 cells

Author keywords

3T3 L1 cells; Adipogenesis; lncRNA; NEAT1; SR proteins

Indexed keywords

CELL PROTEIN; DEXAMETHASONE; IMMUNOGLOBULIN G; ISOBUTYLMETHYLXANTHINE; LONG UNTRANSLATED RNA; LONG UNTRANSLATED RNA NEAT1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; SRP40 PROTEIN; UNCLASSIFIED DRUG;

EID: 84930271544     PISSN: None     EISSN: 20734425     Source Type: Journal    
DOI: 10.3390/genes5041050     Document Type: Article
Times cited : (115)

References (35)
  • 1
    • 33846169089 scopus 로고    scopus 로고
    • Eukaryotic regulatory RNAs: An answer to the “genome complexity” conundrum
    • Prasanth, K.V.; Spector, D.L. Eukaryotic regulatory RNAs: An answer to the “genome complexity” conundrum. Genes Dev. 2007, 21, 11–42
    • (2007) Genes Dev , vol.21 , pp. 11-42
    • Prasanth, K.V.1    Spector, D.L.2
  • 2
    • 77955110979 scopus 로고    scopus 로고
    • Genome-wide computational identification and manual annotation of human long non coding RNA genes
    • Jia, H.; Osak, M.; Bogu, G.K.; Stanton, L.W.; Johnson, R.; Lipovich, L. Genome-wide computational identification and manual annotation of human long non coding RNA genes. RNA 2010, 16, 1478–1487
    • (2010) RNA , vol.16 , pp. 1478-1487
    • Jia, H.1    Osak, M.2    Bogu, G.K.3    Stanton, L.W.4    Johnson, R.5    Lipovich, L.6
  • 4
    • 84871069553 scopus 로고    scopus 로고
    • Epigenetic regulation by long non coding RNAs
    • Lee, J.T. Epigenetic regulation by long non coding RNAs. Science 2012, 338, 1435–1439
    • (2012) Science , vol.338 , pp. 1435-1439
    • Lee, J.T.1
  • 6
    • 42449159377 scopus 로고    scopus 로고
    • SR proteins and related factors in alternative splicing
    • Lin, S.; Fu, X.D. SR proteins and related factors in alternative splicing. Adv. Exp. Med. Biol. 2007, 623, 107–122
    • (2007) Adv. Exp. Med. Biol , vol.623 , pp. 107-122
    • Lin, S.1    Fu, X.D.2
  • 7
    • 79961172897 scopus 로고    scopus 로고
    • Move, regroup: Signaling control of splicing proteins
    • Heyd, F.; Lynch, K.W. Degrade, move, regroup: Signaling control of splicing proteins. Trends Biochem. Sci. 2011, 36, 397–404
    • (2011) Trends Biochem. Sci , vol.36 , pp. 397-404
    • Heyd, F.1    Lynch Degrade, K.W.2
  • 8
    • 84871858673 scopus 로고    scopus 로고
    • Clk/STY (cdc2-Like Kinase 1) and Akt Regulate Alternative Splicing and Adipogenesis in 3T3-L1 Pre-Adipocytes
    • Li, P.; Carter, G.; Romero, J.; Gower, K.M.; Watson, J.; Patel, N.A.; Cooper, D.R. Clk/STY (cdc2-Like Kinase 1) and Akt Regulate Alternative Splicing and Adipogenesis in 3T3-L1 Pre-Adipocytes. PLoS One 2013, 8, e53268
    • (2013) Plos One , vol.8
    • Li, P.1    Carter, G.2    Romero, J.3    Gower, K.M.4    Watson, J.5    Patel, N.A.6    Cooper, D.R.7
  • 9
    • 84855956560 scopus 로고    scopus 로고
    • Long non-coding RNAs in nuclear bodies
    • Ip, J.Y.; Nakagawa, S. Long non-coding RNAs in nuclear bodies. Dev. Growth Differ. 2012, 54, 44–54
    • (2012) Dev. Growth Differ , vol.54 , pp. 44-54
    • Ip, J.Y.1    Nakagawa, S.2
  • 10
    • 62549117314 scopus 로고    scopus 로고
    • An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
    • Clemson, C.M.; Hutchinson, J.N.; Sara, S.A.; Ensminger, A.W.; Fox, A.H.; Chess, A.; Lawrence, J.B. An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol. Cell 2009, 33, 717–726
    • (2009) Mol. Cell , vol.33 , pp. 717-726
    • Clemson, C.M.1    Hutchinson, J.N.2    Sara, S.A.3    Ensminger, A.W.4    Fox, A.H.5    Chess, A.6    Lawrence, J.B.7
  • 11
    • 62449319486 scopus 로고    scopus 로고
    • MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles
    • Sasaki, Y.T.; Ideue, T.; Sano, M.; Mituyama, T.; Hirose, T. MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles. Proc. Natl. Acad. Sci. USA 2009, 106, 2525–2530
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2525-2530
    • Sasaki, Y.T.1    Ideue, T.2    Sano, M.3    Mituyama, T.4    Hirose, T.5
  • 12
    • 61849113891 scopus 로고    scopus 로고
    • MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles
    • Sunwoo, H.; Dinger, M.E.; Wilusz, J.E.; Amaral, P.P.; Mattick, J.S.; Spector, D.L. MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res. 2009, 19, 347–359
    • (2009) Genome Res , vol.19 , pp. 347-359
    • Sunwoo, H.1    Dinger, M.E.2    Wilusz, J.E.3    Amaral, P.P.4    Mattick, J.S.5    Spector, D.L.6
  • 13
    • 33847185603 scopus 로고    scopus 로고
    • A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains
    • Hutchinson, J.N.; Ensminger, A.W.; Clemson, C.M.; Lynch, C.R.; Lawrence, J.B.; Chess, A. A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics 2007, 8, e39
    • (2007) BMC Genomics , vol.8
    • Hutchinson, J.N.1    Ensminger, A.W.2    Clemson, C.M.3    Lynch, C.R.4    Lawrence, J.B.5    Chess, A.6
  • 14
    • 68949212914 scopus 로고    scopus 로고
    • Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA
    • Chen, L.L.; Carmichael, G.G. Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA. Mol. Cell 2009, 35, 467–478
    • (2009) Mol. Cell , vol.35 , pp. 467-478
    • Chen, L.L.1    Carmichael, G.G.2
  • 16
    • 78649339069 scopus 로고    scopus 로고
    • Long noncoding RNA in genome regulation: Prospects and mechanisms
    • Hung, T.; Chang, H.Y. Long noncoding RNA in genome regulation: Prospects and mechanisms. RNA Biol. 2010, 7, 582–585
    • (2010) RNA Biol , vol.7 , pp. 582-585
    • Hung, T.1    Chang, H.Y.2
  • 17
    • 0041669439 scopus 로고    scopus 로고
    • Nuclear speckles: A model for nuclear organelles
    • Lamond, A.I.; Spector, D.L. Nuclear speckles: A model for nuclear organelles. Nat. Rev. Mol. Cell Biol. 2003, 4, 605–612
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 605-612
    • Lamond, A.I.1    Spector, D.L.2
  • 18
    • 0344429906 scopus 로고    scopus 로고
    • MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
    • Ji, P.; Diederichs, S.; Wang, W.; Boing, S.; Metzger, R.; Schneider, P.M.; Tidow, N.; Brandt, B.; Buerger, H.; Bulk, E., et al. MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 2003, 22, 8031–8041
    • (2003) Oncogene , vol.22 , pp. 8031-8041
    • Ji, P.1    Diederichs, S.2    Wang, W.3    Boing, S.4    Metzger, R.5    Schneider, P.M.6    Tidow, N.7    Brandt, B.8    Buerger, H.9    Bulk, E.10
  • 19
  • 20
    • 84865628181 scopus 로고    scopus 로고
    • Paraspeckle nuclear bodies—Useful uselessness?
    • Nakagawa, S.; Hirose, T. Paraspeckle nuclear bodies—Useful uselessness? Cell. Mol. Life Sci. 2012, 69, 3027–3036
    • (2012) Cell. Mol. Life Sci , vol.69 , pp. 3027-3036
    • Nakagawa, S.1    Hirose, T.2
  • 21
    • 66449111724 scopus 로고    scopus 로고
    • Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid
    • Jiang, K.; Patel, N.A.; Watson, J.E.; Apostolatos, H.; Kleiman, E.; Hanson, O.; Hagiwara, M.; Cooper, D.R. Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid. Endocrinology 2009, 150, 2087–2097
    • (2009) Endocrinology , vol.150 , pp. 2087-2097
    • Jiang, K.1    Patel, N.A.2    Watson, J.E.3    Apostolatos, H.4    Kleiman, E.5    Hanson, O.6    Hagiwara, M.7    Cooper, D.R.8
  • 22
    • 79955506825 scopus 로고    scopus 로고
    • Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice
    • Nakagawa, S.; Naganuma, T.; Shioi, G.; Hirose, T. Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice. J. Cell Biol. 2011, 193, 31–39
    • (2011) J. Cell Biol , vol.193 , pp. 31-39
    • Nakagawa, S.1    Naganuma, T.2    Shioi, G.3    Hirose, T.4
  • 24
    • 33845984572 scopus 로고    scopus 로고
    • Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis
    • Zhang, Y.L.; Hernandez-Ono, A.; Siri, P.; Weisberg, S.; Conlon, D.; Graham, M.J.; Crooke, R.M.; Huang, L.S.; Ginsberg, H.N. Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis. J. Biol. Chem.2006, 281, 37603–37615
    • (2006) J. Biol. Chem , vol.281 , pp. 37603-37615
    • Zhang, Y.L.1    Hernandez-Ono, A.2    Siri, P.3    Weisberg, S.4    Conlon, D.5    Graham, M.J.6    Crooke, R.M.7    Huang, L.S.8    Ginsberg, H.N.9
  • 25
    • 84938845661 scopus 로고    scopus 로고
    • Applied Biosystems, Life Technologies, Grand Island, NY, USA
    • SDS software, version 2.0. Applied Biosystems, Life Technologies, Grand Island, NY, USA, 2013
    • (2013) SDS Software, Version 2.0
  • 26
    • 0028180070 scopus 로고
    • MPPAR gamma 2: Tissuespecific regulator of an adipocyte enhancer
    • Tontonoz, P.; Hu, E.; Graves, R.A.; Budavari, A.I.; Spiegelman, B.M. mPPAR gamma 2: Tissuespecific regulator of an adipocyte enhancer. Genes Dev. 1994, 8, 1224–1234
    • (1994) Genes Dev , vol.8 , pp. 1224-1234
    • Tontonoz, P.1    Hu, E.2    Graves, R.A.3    Budavari, A.I.4    Spiegelman, B.M.5
  • 27
    • 0029102676 scopus 로고
    • Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: Alternative promoter use and different splicing yield two mPPAR gamma isoforms
    • Zhu, Y.; QI, C.; Korenberg, J.R.; Chen, X.N.; Noya, D.; Rao, M.S.; Reddy, J.K. Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: Alternative promoter use and different splicing yield two mPPAR gamma isoforms. Proc. Natl. Acad. Sci. USA 1995, 92, 7921–7925
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7921-7925
    • Zhu, Y.1    Qi, C.2    Korenberg, J.R.3    Chen, X.N.4    Noya, D.5    Rao, M.S.6    Reddy, J.K.7
  • 28
    • 84938843147 scopus 로고    scopus 로고
    • Department of Molecular Medicine, USF Morsani College of Medicine, and J.A. Haley Veterans Hospital, Tampa, FL, USA; Unpublished data
    • Cooper, D.R.; Patel, N.A. Department of Molecular Medicine, USF Morsani College of Medicine, and J.A. Haley Veterans Hospital, Tampa, FL, USA; Unpublished data, 2012
    • (2012)
    • Cooper, D.R.1    Patel, N.A.2
  • 29
    • 0030977450 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
    • Vidal-Puig, A.J.; Considine, R.V.; Jimenez-Linan, M.; Werman, A.; Pories, W.J.; Caro, J.F.; Flier, J.S. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J. Clin. Invest.1997, 99, 2416–2422
    • (1997) J. Clin. Invest , vol.99 , pp. 2416-2422
    • Vidal-Puig, A.J.1    Considine, R.V.2    Jimenez-Linan, M.3    Werman, A.4    Pories, W.J.5    Caro, J.F.6    Flier, J.S.7
  • 30
    • 84938850797 scopus 로고    scopus 로고
    • GraphPad Prism: LaJolla, CA, USA
    • Prism6 software. GraphPad Prism: LaJolla, CA, USA, 2013
    • (2013) Prism6 Software
  • 32
    • 0035933893 scopus 로고    scopus 로고
    • Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells
    • Patel, N.A.; Chalfant, C.E.; Watson, J.E.; Wyatt, J.R.; Dean, N.M.; Eichler, D.C.; Cooper, D.R. Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells. J. Biol. Chem. 2001, 276, 22648–22654
    • (2001) J. Biol. Chem , vol.276 , pp. 22648-22654
    • Patel, N.A.1    Chalfant, C.E.2    Watson, J.E.3    Wyatt, J.R.4    Dean, N.M.5    Eichler, D.C.6    Cooper, D.R.7
  • 33
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer, S.R. Transcriptional control of adipocyte formation. Cell Metab. 2006, 4, 263–273
    • (2006) Cell Metab , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 35
    • 84884582059 scopus 로고    scopus 로고
    • Long non-coding RNAs: Modulators of nuclear structure and function
    • Bergmann, J.H.; Spector, D.L. Long non-coding RNAs: Modulators of nuclear structure and function. Curr. Opin. Cell Biol. 2014, 26, 10–18.
    • (2014) Curr. Opin. Cell Biol , vol.26 , pp. 10-18
    • Bergmann, J.H.1    Spector, D.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.