메뉴 건너뛰기




Volumn 20, Issue 3, 2015, Pages 251-258

Microengineered Vascular Systems for Drug Development

Author keywords

fabrication; lab on a chip; microfluidics; microtechnology; nanobiotech; nanotechnology

Indexed keywords

CARDIOVASCULAR SYSTEM; FABRICATION; LAB-ON-A-CHIP; MICROFLUIDICS; NANOTECHNOLOGY; TARGETED DRUG DELIVERY;

EID: 84930242377     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068214560767     Document Type: Review
Times cited : (11)

References (76)
  • 1
    • 84861347499 scopus 로고    scopus 로고
    • Tubular Hydrogels of Circumferentially Aligned Nanofibers to Encapsulate and Orient Vascular Cells
    • McClendon M. T.,Stupp S. I.Tubular Hydrogels of Circumferentially Aligned Nanofibers to Encapsulate and Orient Vascular Cells.Biomaterials. 2012;33:5713-5722
    • (2012) Biomaterials , vol.33 , pp. 5713-5722
    • McClendon, M.T.1    Stupp, S.I.2
  • 3
    • 84898802520 scopus 로고    scopus 로고
    • Biomimetic Engineered Muscle with Capacity for Vascular Integration and Functional Maturation In Vivo
    • ,,, et al.. ;:-
    • Juhas M.,Engelmayr G. C.,Fontanella A. N., et al.Biomimetic Engineered Muscle with Capacity for Vascular Integration and Functional Maturation In Vivo.Proc. Natl. Acad. Sci. U. S. A. 2014;111:5508-5513
    • (2014) Proc. Natl. Acad. Sci. U. S. A , vol.111 , pp. 5508-5513
    • Juhas, M.1    Engelmayr, G.C.2    Fontanella, A.N.3
  • 4
    • 84911915002 scopus 로고    scopus 로고
    • Fabrication and In Vivo Microanastomosis of Vascularized Tissue-Engineered Constructs
    • ,,, et al.. ;:-
    • Hooper R. C.,Hernandez K. A.,Boyko T., et al.Fabrication and In Vivo Microanastomosis of Vascularized Tissue-Engineered Constructs.Tissue Eng. Part A. 2014;20:2711-2719
    • (2014) Tissue Eng. Part A , vol.20 , pp. 2711-2719
    • Hooper, R.C.1    Hernandez, K.A.2    Boyko, T.3
  • 5
    • 0031666409 scopus 로고    scopus 로고
    • In Vitro Reconstruction of a Human Capillary-Like Network in a Tissue-Engineered Skin Equivalent
    • ,,, et al.. ;:-
    • Black A. F.,Berthod F.,L’Heureux N., et al.In Vitro Reconstruction of a Human Capillary-Like Network in a Tissue-Engineered Skin Equivalent.FASEB J. 1998;12:1331-1340
    • (1998) FASEB J , vol.12 , pp. 1331-1340
    • Black, A.F.1    Berthod, F.2    L’Heureux, N.3
  • 6
    • 84891523081 scopus 로고    scopus 로고
    • In Vivo Bone Regeneration Using Tubular Perfusion System Bioreactor Cultured Nanofibrous Scaffolds
    • ,,, et al.. ;:-
    • Yeatts A. B.,Both S. K.,Yang W., et al.In Vivo Bone Regeneration Using Tubular Perfusion System Bioreactor Cultured Nanofibrous Scaffolds.Tissue Eng. Part A. 2014;20:139-146
    • (2014) Tissue Eng. Part A , vol.20 , pp. 139-146
    • Yeatts, A.B.1    Both, S.K.2    Yang, W.3
  • 7
    • 79960527448 scopus 로고    scopus 로고
    • The Role of Body-on-a-Chip Devices in Drug and Toxicity Studies
    • Esch M. B.,King T. L.,Shuler M. L.The Role of Body-on-a-Chip Devices in Drug and Toxicity Studies.Annu. Rev. Biomed. Eng. 2011;13:55-72
    • (2011) Annu. Rev. Biomed. Eng , vol.13 , pp. 55-72
    • Esch, M.B.1    King, T.L.2    Shuler, M.L.3
  • 8
    • 84862117005 scopus 로고    scopus 로고
    • Organs-on-a-Chip: A Focus on Compartmentalized Microdevices
    • ,,, et al.. ;:-
    • Moraes C.,Mehta G.,Lesher-Perez S. C., et al.Organs-on-a-Chip: A Focus on Compartmentalized Microdevices.Ann. Biomed. Eng. 2012;40:1211-1227
    • (2012) Ann. Biomed. Eng , vol.40 , pp. 1211-1227
    • Moraes, C.1    Mehta, G.2    Lesher-Perez, S.C.3
  • 9
    • 84864204529 scopus 로고    scopus 로고
    • Microfluidic Models of Vascular Functions
    • ,,, et al.. ;:-
    • Wong K. H.,Chan J. M.,Kamm R. D., et al.Microfluidic Models of Vascular Functions.Annu. Rev. Biomed. Eng. 2012;14:205-230
    • (2012) Annu. Rev. Biomed. Eng , vol.14 , pp. 205-230
    • Wong, K.H.1    Chan, J.M.2    Kamm, R.D.3
  • 10
    • 33646943472 scopus 로고    scopus 로고
    • Formation of Perfused, Functional Microvascular Tubes In Vitro
    • Chrobak K. M.,Potter D. R.,Tien J.Formation of Perfused, Functional Microvascular Tubes In Vitro.Microvasc. Res. 2006;71:185-196
    • (2006) Microvasc. Res , vol.71 , pp. 185-196
    • Chrobak, K.M.1    Potter, D.R.2    Tien, J.3
  • 11
    • 79952201289 scopus 로고    scopus 로고
    • Methods for Forming Human Microvascular Tubes In Vitro and Measuring Their Macromolecular Permeability
    • Price G. M.,Tien J.Methods for Forming Human Microvascular Tubes In Vitro and Measuring Their Macromolecular Permeability.Methods Mol. Biol. 2011;671:281-293
    • (2011) Methods Mol. Biol , vol.671 , pp. 281-293
    • Price, G.M.1    Tien, J.2
  • 12
    • 84876704168 scopus 로고    scopus 로고
    • Engineering of Functional, Perfusable 3D Microvascular Networks on a Chip
    • Kim S.,Lee H.,Chung M.,Jeon N. L.Engineering of Functional, Perfusable 3D Microvascular Networks on a Chip.Lab Chip. 2013;13:1489-1500
    • (2013) Lab Chip , vol.13 , pp. 1489-1500
    • Kim, S.1    Lee, H.2    Chung, M.3    Jeon, N.L.4
  • 13
    • 84881144606 scopus 로고    scopus 로고
    • A Microfluidic Anti-Factor Xa Assay Device for Point of Care Monitoring of Anticoagulation Therapy
    • ,,, et al.. ;:-
    • Harris L. F.,Rainey P.,Castro-Lopez V., et al.A Microfluidic Anti-Factor Xa Assay Device for Point of Care Monitoring of Anticoagulation Therapy.Analyst. 2013;138:4769-4776
    • (2013) Analyst , vol.138 , pp. 4769-4776
    • Harris, L.F.1    Rainey, P.2    Castro-Lopez, V.3
  • 14
    • 84875853372 scopus 로고    scopus 로고
    • A Centrifugally Actuated Point-of-Care Testing System for the Surface Acoustic Wave Immunosensing of Cardiac Troponin I
    • ,,, et al.. ;:-
    • Lee W.,Jung J.,Hahn Y. K., et al.A Centrifugally Actuated Point-of-Care Testing System for the Surface Acoustic Wave Immunosensing of Cardiac Troponin I.Analyst. 2013;138:2558-2566
    • (2013) Analyst , vol.138 , pp. 2558-2566
    • Lee, W.1    Jung, J.2    Hahn, Y.K.3
  • 15
    • 56549119892 scopus 로고    scopus 로고
    • Development of a Digital Microfluidic Platform for Point of Care Testing
    • ,,, et al.. ;:-
    • Sista R.,Hua Z.,Thwar P., et al.Development of a Digital Microfluidic Platform for Point of Care Testing.Lab Chip. 2008;8:2091-2104
    • (2008) Lab Chip , vol.8 , pp. 2091-2104
    • Sista, R.1    Hua, Z.2    Thwar, P.3
  • 16
    • 84862231072 scopus 로고    scopus 로고
    • Commercialization of Microfluidic Point-of-Care Diagnostic Devices
    • Chin C. D.,Linder V.,Sia S. K.Commercialization of Microfluidic Point-of-Care Diagnostic Devices.Lab Chip. 2012;12:2118-2134
    • (2012) Lab Chip , vol.12 , pp. 2118-2134
    • Chin, C.D.1    Linder, V.2    Sia, S.K.3
  • 17
    • 36048979880 scopus 로고    scopus 로고
    • Vascular Adhesion Molecules in Atherosclerosis
    • Galkina E.,Ley K.Vascular Adhesion Molecules in Atherosclerosis.Arterioscler. Thromb. Vasc. Biol. 2007;27:2292-2301
    • (2007) Arterioscler. Thromb. Vasc. Biol , vol.27 , pp. 2292-2301
    • Galkina, E.1    Ley, K.2
  • 18
    • 70449727200 scopus 로고    scopus 로고
    • Microemboli and Microvascular Obstruction in Acute Coronary Thrombosis and Sudden Coronary Death: Relation to Epicardial Plaque Histopathology
    • ,,, et al.. ;:-
    • Schwartz R. S.,Burke A.,Farb A., et al.Microemboli and Microvascular Obstruction in Acute Coronary Thrombosis and Sudden Coronary Death: Relation to Epicardial Plaque Histopathology.J. Am. Coll. Cardiol. 2009;54:2167-2173
    • (2009) J. Am. Coll. Cardiol , vol.54 , pp. 2167-2173
    • Schwartz, R.S.1    Burke, A.2    Farb, A.3
  • 20
    • 84896752543 scopus 로고    scopus 로고
    • Microfluidic Thrombosis under Multiple Shear Rates and Antiplatelet Therapy Doses
    • ,,, et al.. ;:
    • Li M.,Hotaling N. A.,Ku D. N., et al.Microfluidic Thrombosis under Multiple Shear Rates and Antiplatelet Therapy Doses.PLoS One. 2014;9:e82493
    • (2014) PLoS One , vol.9 , pp. 82493
    • Li, M.1    Hotaling, N.A.2    Ku, D.N.3
  • 21
    • 84892921738 scopus 로고    scopus 로고
    • Probing Nanoparticle Translocation across the Permeable Endothelium in Experimental Atherosclerosis
    • ,,, et al.. ;:-
    • Kim Y.,Lobatto M. E.,Kawahara T., et al.Probing Nanoparticle Translocation across the Permeable Endothelium in Experimental Atherosclerosis.Proc. Natl. Acad. Sci. U. S. A. 2014;111:1078-1083
    • (2014) Proc. Natl. Acad. Sci. U. S. A , vol.111 , pp. 1078-1083
    • Kim, Y.1    Lobatto, M.E.2    Kawahara, T.3
  • 22
    • 67650875881 scopus 로고    scopus 로고
    • Vascular Extracellular Matrix and Arterial Mechanics
    • Wagenseil J. E.,Mecham R. P.Vascular Extracellular Matrix and Arterial Mechanics.Physiol. Rev. 2009;89:957-989
    • (2009) Physiol. Rev , vol.89 , pp. 957-989
    • Wagenseil, J.E.1    Mecham, R.P.2
  • 23
    • 84855468373 scopus 로고    scopus 로고
    • In Vitro Modeling of the Microvascular Occlusion and Thrombosis That Occur in Hematologic Diseases Using Microfluidic Technology
    • ,,, et al.. ;:-
    • Tsai M.,Kita A.,Leach J., et al.In Vitro Modeling of the Microvascular Occlusion and Thrombosis That Occur in Hematologic Diseases Using Microfluidic Technology.J. Clin. Invest. 2012;122:408-418
    • (2012) J. Clin. Invest , vol.122 , pp. 408-418
    • Tsai, M.1    Kita, A.2    Leach, J.3
  • 24
    • 84862197029 scopus 로고    scopus 로고
    • In Vitro Microvessels for the Study of Angiogenesis and Thrombosis
    • ,,, et al.. ;:-
    • Zheng Y.,Chen J.,Craven M., et al.In Vitro Microvessels for the Study of Angiogenesis and Thrombosis.Proc. Natl. Acad. Sci. U. S. A. 2012;109:9342-9347
    • (2012) Proc. Natl. Acad. Sci. U. S. A , vol.109 , pp. 9342-9347
    • Zheng, Y.1    Chen, J.2    Craven, M.3
  • 25
    • 84870774465 scopus 로고    scopus 로고
    • Reducing Safety-Related Drug Attrition: The Use of In Vitro Pharmacological Profiling
    • ,,, et al.. ;:-
    • Bowes J.,Brown A. J.,Hamon J., et al.Reducing Safety-Related Drug Attrition: The Use of In Vitro Pharmacological Profiling.Nat. Rev. Drug Discov. 2012;11:909-922
    • (2012) Nat. Rev. Drug Discov , vol.11 , pp. 909-922
    • Bowes, J.1    Brown, A.J.2    Hamon, J.3
  • 26
    • 0001425086 scopus 로고    scopus 로고
    • Limits of Lithography
    • Harriott L. R.Limits of Lithography.Proc. IEEE. 2001;89:366-374
    • (2001) Proc. IEEE , vol.89 , pp. 366-374
    • Harriott, L.R.1
  • 27
    • 84887012341 scopus 로고    scopus 로고
    • Microfabrication of Human Organs-on-Chips
    • ,,, et al.. ;:-
    • Huh D.,Kim H. J.,Fraser J. P., et al.Microfabrication of Human Organs-on-Chips.Nat. Protoc. 2013;8:2135-2157
    • (2013) Nat. Protoc , vol.8 , pp. 2135-2157
    • Huh, D.1    Kim, H.J.2    Fraser, J.P.3
  • 28
    • 0037452586 scopus 로고    scopus 로고
    • Gray-Scale Photolithography Using Microfluidic Photomasks
    • Chen C.,Hirdes D.,Folch A.Gray-Scale Photolithography Using Microfluidic Photomasks.Proc. Natl. Acad. Sci. U. S. A. 2003;100:1499-1504
    • (2003) Proc. Natl. Acad. Sci. U. S. A , vol.100 , pp. 1499-1504
    • Chen, C.1    Hirdes, D.2    Folch, A.3
  • 29
    • 4344593980 scopus 로고    scopus 로고
    • Femtosecond Pulsed Laser Micromachining of Glass Substrates with Application to Microfluidic Devices
    • ,,, et al.. ;:-
    • Giridhar M. S.,Seong K.,Schulzgen A., et al.Femtosecond Pulsed Laser Micromachining of Glass Substrates with Application to Microfluidic Devices.Appl. Opt. 2004;43:4584-4589
    • (2004) Appl. Opt , vol.43 , pp. 4584-4589
    • Giridhar, M.S.1    Seong, K.2    Schulzgen, A.3
  • 30
    • 84869028052 scopus 로고    scopus 로고
    • Nanosecond Pulsed Laser Micromachining of PMMA-Based Microfluidic Channels
    • ,,, et al.. ;:-
    • Teixidor D.,Thepsonthi T.,Ciurana J., et al.Nanosecond Pulsed Laser Micromachining of PMMA-Based Microfluidic Channels.J. Manufact. Process. 2012;14:435-442
    • (2012) J. Manufact. Process , vol.14 , pp. 435-442
    • Teixidor, D.1    Thepsonthi, T.2    Ciurana, J.3
  • 31
    • 79953199826 scopus 로고    scopus 로고
    • Fabrication of Circular Microfluidic Channels by Combining Mechanical Micromilling and Soft Lithography
    • ,,, et al.. ;:-
    • Wilson M. E.,Kota N.,Kim Y., et al.Fabrication of Circular Microfluidic Channels by Combining Mechanical Micromilling and Soft Lithography.Lab Chip. 2011;11:1550-1555
    • (2011) Lab Chip , vol.11 , pp. 1550-1555
    • Wilson, M.E.1    Kota, N.2    Kim, Y.3
  • 32
    • 84901915693 scopus 로고    scopus 로고
    • Hydrogel Bioprinted Microchannel Networks for Vascularization of Tissue Engineering Constructs
    • ,,, et al.. ;:-
    • Bertassoni L. E.,Cecconi M.,Manoharan V., et al.Hydrogel Bioprinted Microchannel Networks for Vascularization of Tissue Engineering Constructs.Lab Chip. 2014;14:2202-2211
    • (2014) Lab Chip , vol.14 , pp. 2202-2211
    • Bertassoni, L.E.1    Cecconi, M.2    Manoharan, V.3
  • 33
    • 84906938147 scopus 로고    scopus 로고
    • Generation of Multi-Scale Vascular Network System within 3D Hydrogel Using 3D Bio-Printing Technology
    • ,,, et al.. ;:-
    • Lee V.,Lanzi A.,Ngo H., et al.Generation of Multi-Scale Vascular Network System within 3D Hydrogel Using 3D Bio-Printing Technology.Cell. Mol. Bioeng. 2014;7:460-472
    • (2014) Cell. Mol. Bioeng , vol.7 , pp. 460-472
    • Lee, V.1    Lanzi, A.2    Ngo, H.3
  • 34
    • 84865202010 scopus 로고    scopus 로고
    • Configurable 3D-Printed Millifluidic and Microfluidic ‘Lab on a Chip’ Reactionware Devices
    • ,,, et al.. ;:-
    • Kitson P. J.,Rosnes M. H.,Sans V., et al.Configurable 3D-Printed Millifluidic and Microfluidic ‘Lab on a Chip’ Reactionware Devices.Lab Chip. 2012;12:3267-3271
    • (2012) Lab Chip , vol.12 , pp. 3267-3271
    • Kitson, P.J.1    Rosnes, M.H.2    Sans, V.3
  • 35
    • 37349003030 scopus 로고    scopus 로고
    • Shrinky-Dink Microfluidics: Rapid Generation of Deep and Rounded Patterns
    • ,,, et al.. ;:-
    • Grimes A.,Breslauer D. N.,Long M., et al.Shrinky-Dink Microfluidics: Rapid Generation of Deep and Rounded Patterns.Lab Chip. 2008;8:170-172
    • (2008) Lab Chip , vol.8 , pp. 170-172
    • Grimes, A.1    Breslauer, D.N.2    Long, M.3
  • 36
    • 84878101085 scopus 로고    scopus 로고
    • Paper-Based Microfluidic Point-of-Care Diagnostic Devices
    • Yetisen A. K.,Akram M. S.,Lowe C. R.Paper-Based Microfluidic Point-of-Care Diagnostic Devices.Lab Chip. 2013;13:2210-2251
    • (2013) Lab Chip , vol.13 , pp. 2210-2251
    • Yetisen, A.K.1    Akram, M.S.2    Lowe, C.R.3
  • 37
    • 75149182255 scopus 로고    scopus 로고
    • Low-Cost Rapid Prototyping of Flexible Microfluidic Devices Using a Desktop Digital Craft Cutter
    • Yuen P. K.,Goral V. N.Low-Cost Rapid Prototyping of Flexible Microfluidic Devices Using a Desktop Digital Craft Cutter.Lab Chip. 2010;10:384-387
    • (2010) Lab Chip , vol.10 , pp. 384-387
    • Yuen, P.K.1    Goral, V.N.2
  • 38
    • 84903867681 scopus 로고    scopus 로고
    • Low Cost Production of Disposable Microfluidics by Blister Packaging Technology
    • Disch A.,Mueller C.,Reinecke H.Low Cost Production of Disposable Microfluidics by Blister Packaging Technology.Conf. Proc. IEEE Eng. Med. Biol. Soc. 2007;2007:6323-6326
    • (2007) Conf. Proc. IEEE Eng. Med. Biol. Soc , vol.2007 , pp. 6323-6326
    • Disch, A.1    Mueller, C.2    Reinecke, H.3
  • 39
    • 77952616543 scopus 로고    scopus 로고
    • Lab-on-a-Foil: Microfluidics on Thin and Flexible Films
    • ,,, et al.. ;:-
    • Focke M.,Kosse D.,Muller C., et al.Lab-on-a-Foil: Microfluidics on Thin and Flexible Films.Lab Chip. 2010;10:1365-1386
    • (2010) Lab Chip , vol.10 , pp. 1365-1386
    • Focke, M.1    Kosse, D.2    Muller, C.3
  • 40
    • 77954471119 scopus 로고    scopus 로고
    • Transferring Vertically Aligned Carbon Nanotubes onto a Polymeric Substrate Using a Hot Embossing Technique for Microfluidic Applications
    • Mathur A.,Roy S. S.,McLaughlin J. A.Transferring Vertically Aligned Carbon Nanotubes onto a Polymeric Substrate Using a Hot Embossing Technique for Microfluidic Applications.J. R. Soc. Interface. 2010;7:1129-1133
    • (2010) J. R. Soc. Interface , vol.7 , pp. 1129-1133
    • Mathur, A.1    Roy, S.S.2    McLaughlin, J.A.3
  • 41
    • 84887577448 scopus 로고    scopus 로고
    • Microfluidic Approaches for Engineering Vasculature
    • Tien J.Microfluidic Approaches for Engineering Vasculature.Curr. Opin. Chem. Eng. 2014;3:36-41
    • (2014) Curr. Opin. Chem. Eng , vol.3 , pp. 36-41
    • Tien, J.1
  • 42
    • 84876719079 scopus 로고    scopus 로고
    • Engineering a 3D Vascular Network in Hydrogel for Mimicking a Nephron
    • ,,, et al.. ;:-
    • Mu X.,Zheng W.,Xiao L., et al.Engineering a 3D Vascular Network in Hydrogel for Mimicking a Nephron.Lab Chip. 2013;13:1612-1618
    • (2013) Lab Chip , vol.13 , pp. 1612-1618
    • Mu, X.1    Zheng, W.2    Xiao, L.3
  • 43
    • 84904257856 scopus 로고    scopus 로고
    • Microstructured Extracellular Matrices in Tissue Engineering and Development: An Update
    • Tien J.,Nelson C. M.Microstructured Extracellular Matrices in Tissue Engineering and Development: An Update.Ann. Biomed. Eng. 2014;42:1413-1423
    • (2014) Ann. Biomed. Eng , vol.42 , pp. 1413-1423
    • Tien, J.1    Nelson, C.M.2
  • 44
    • 4344645978 scopus 로고    scopus 로고
    • Can the Pharmaceutical Industry Reduce Attrition Rates?
    • Kola I.,Landis J.Can the Pharmaceutical Industry Reduce Attrition Rates?.Nat. Rev. Drug Discov. 2004;3:711-715
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 45
    • 84877747508 scopus 로고    scopus 로고
    • Blood-Brain Barrier Structure and Function and the Challenges for CNS Drug Delivery
    • Abbott N. J.Blood-Brain Barrier Structure and Function and the Challenges for CNS Drug Delivery.J. Inherit. Metab. Dis. 2013;36:437-449
    • (2013) J. Inherit. Metab. Dis , vol.36 , pp. 437-449
    • Abbott, N.J.1
  • 46
    • 0033755180 scopus 로고    scopus 로고
    • The Blood-Brain and Blood-Tumor Barriers: A Review of Strategies for Increasing Drug Delivery
    • Groothuis D. R.The Blood-Brain and Blood-Tumor Barriers: A Review of Strategies for Increasing Drug Delivery.Neuro. Oncol. 2000;2:45-59
    • (2000) Neuro. Oncol , vol.2 , pp. 45-59
    • Groothuis, D.R.1
  • 47
    • 84904264611 scopus 로고    scopus 로고
    • Blood-Brain Barrier Models and Their Relevance for a Successful Development of CNS Drug Delivery Systems: A Review
    • ,,, et al.. ;:-
    • Bicker J.,Alves G.,Fortuna A., et al.Blood-Brain Barrier Models and Their Relevance for a Successful Development of CNS Drug Delivery Systems: A Review.Eur. J. Pharm. Biopharm. 2014;87:409-432
    • (2014) Eur. J. Pharm. Biopharm , vol.87 , pp. 409-432
    • Bicker, J.1    Alves, G.2    Fortuna, A.3
  • 48
    • 12244300933 scopus 로고    scopus 로고
    • Drug Delivery and In Vitro Models of the Blood-Brain Barrier
    • ,,, et al.. ;:-
    • Cucullo L.,Aumayr B.,Rapp E., et al.Drug Delivery and In Vitro Models of the Blood-Brain Barrier.Curr. Opin. Drug Discov. Dev. 2005;8:89-99
    • (2005) Curr. Opin. Drug Discov. Dev , vol.8 , pp. 89-99
    • Cucullo, L.1    Aumayr, B.2    Rapp, E.3
  • 49
    • 84857463177 scopus 로고    scopus 로고
    • In Vitro Blood-Brain Barrier Models: Current and Perspective Technologies
    • Naik P.,Cucullo L.In Vitro Blood-Brain Barrier Models: Current and Perspective Technologies.J. Pharm. Sci. 2012;101:1337-1354
    • (2012) J. Pharm. Sci , vol.101 , pp. 1337-1354
    • Naik, P.1    Cucullo, L.2
  • 50
    • 84875763552 scopus 로고    scopus 로고
    • Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier
    • ,,, et al.. ;:
    • Urich E.,Patsch C.,Aigner S., et al.Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier.Sci. Rep. 2013 1500;3:
    • (2013) Sci. Rep , vol.3
    • Urich, E.1    Patsch, C.2    Aigner, S.3
  • 51
    • 84857015402 scopus 로고    scopus 로고
    • Parallel-Plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress
    • ,,, et al.. ;:
    • Lane W. O.,Jantzen A. E.,Carlon T. A., et al.Parallel-Plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress.J. Vis. Exp. 2012;17:3349
    • (2012) J. Vis. Exp , vol.17 , pp. 3349
    • Lane, W.O.1    Jantzen, A.E.2    Carlon, T.A.3
  • 52
    • 79551646674 scopus 로고    scopus 로고
    • A Dynamic In Vitro BBB Model for the Study of Immune Cell Trafficking into the Central Nervous System
    • ,,, et al.. ;:-
    • Cucullo L.,Marchi N.,Hossain M., et al.A Dynamic In Vitro BBB Model for the Study of Immune Cell Trafficking into the Central Nervous System.J. Cereb. Blood Flow Metab. 2011;31:767-777
    • (2011) J. Cereb. Blood Flow Metab , vol.31 , pp. 767-777
    • Cucullo, L.1    Marchi, N.2    Hossain, M.3
  • 53
    • 84900023528 scopus 로고    scopus 로고
    • In Vitro Models of the Blood-Brain Barrier for the Study of Drug Delivery to the Brain
    • Wilhelm I.,Krizbai I. A.In Vitro Models of the Blood-Brain Barrier for the Study of Drug Delivery to the Brain.Mol. Pharm. 2014;11:1949-1963
    • (2014) Mol. Pharm , vol.11 , pp. 1949-1963
    • Wilhelm, I.1    Krizbai, I.A.2
  • 54
    • 84860366574 scopus 로고    scopus 로고
    • Characterization of a Microfluidic In Vitro Model of the Blood-Brain Barrier (muBBB)
    • Booth R.,Kim H.Characterization of a Microfluidic In Vitro Model of the Blood-Brain Barrier (muBBB).Lab Chip. 2012;12:1784-1792
    • (2012) Lab Chip , vol.12 , pp. 1784-1792
    • Booth, R.1    Kim, H.2
  • 55
    • 84875833460 scopus 로고    scopus 로고
    • SyM-BBB: A Microfluidic Blood Brain Barrier Model
    • ,,, et al.. ;:-
    • Prabhakarpandian B.,Shen M. C.,Nichols J. B., et al.SyM-BBB: A Microfluidic Blood Brain Barrier Model.Lab Chip. 2013;13:1093-1101
    • (2013) Lab Chip , vol.13 , pp. 1093-1101
    • Prabhakarpandian, B.1    Shen, M.C.2    Nichols, J.B.3
  • 56
    • 84872610509 scopus 로고    scopus 로고
    • BBB on Chip: Microfluidic Platform to Mechanically and Biochemically Modulate Blood-Brain Barrier Function
    • ,,, et al.. ;:-
    • Griep L. M.,Wolbers F.,de Wagenaar B., et al.BBB on Chip: Microfluidic Platform to Mechanically and Biochemically Modulate Blood-Brain Barrier Function.Biomed Microdevices. 2013;15:145-150
    • (2013) Biomed Microdevices , vol.15 , pp. 145-150
    • Griep, L.M.1    Wolbers, F.2    de Wagenaar, B.3
  • 57
    • 84877043911 scopus 로고    scopus 로고
    • Reliable Permeability Assay System in a Microfluidic Device Mimicking Cerebral Vasculatures
    • ,,, et al.. ;:-
    • Yeon J. H.,Na D.,Choi K., et al.Reliable Permeability Assay System in a Microfluidic Device Mimicking Cerebral Vasculatures.Biomed. Microdevices. 2012;14:1141-1148
    • (2012) Biomed. Microdevices , vol.14 , pp. 1141-1148
    • Yeon, J.H.1    Na, D.2    Choi, K.3
  • 58
    • 64649093618 scopus 로고    scopus 로고
    • Thin-Walled Microvessels in Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions Relevance of Compromised Structural Integrity for Intraplaque Microvascular Leakage
    • ,,, et al.. ;:-
    • Sluimer J. C.,Kolodgie F. D.,Bijnens A. P., et al.Thin-Walled Microvessels in Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions Relevance of Compromised Structural Integrity for Intraplaque Microvascular Leakage.J. Am. Coll. Cardiol. 2009;53:1517-1527
    • (2009) J. Am. Coll. Cardiol , vol.53 , pp. 1517-1527
    • Sluimer, J.C.1    Kolodgie, F.D.2    Bijnens, A.P.3
  • 59
    • 84893651437 scopus 로고    scopus 로고
    • Heart Disease and Stroke Statistics—2014 Update: A Report from the American Heart Association
    • ,,, et al.. ;:-
    • Go A. S.,Mozaffarian D.,Roger V. L., et al.Heart Disease and Stroke Statistics—2014 Update: A Report from the American Heart Association.Circulation. 2014;129:e28-e292
    • (2014) Circulation , vol.129 , pp. 28-292
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 60
    • 2942733214 scopus 로고    scopus 로고
    • Role of Endothelial Dysfunction in Atherosclerosis
    • Davignon J.,Ganz P.Role of Endothelial Dysfunction in Atherosclerosis.Circulation. 2004;109:III27-III32
    • (2004) Circulation , vol.109 , pp. II27-II32
    • Davignon, J.1    Ganz, P.2
  • 61
    • 0036080373 scopus 로고    scopus 로고
    • Mouse Models of Atherosclerosis
    • Daugherty A.Mouse Models of Atherosclerosis.Am. J. Med. Sci. 2002;323:3-10
    • (2002) Am. J. Med. Sci , vol.323 , pp. 3-10
    • Daugherty, A.1
  • 62
    • 73949111725 scopus 로고    scopus 로고
    • Modes of Defining Atherosclerosis in Mouse Models: Relative Merits and Evolving Standards
    • ,,, et al.. ;:-
    • Daugherty A.,Lu H.,Howatt D. A., et al.Modes of Defining Atherosclerosis in Mouse Models: Relative Merits and Evolving Standards.Methods Mol. Biol. 2009;573:1-15
    • (2009) Methods Mol. Biol , vol.573 , pp. 1-15
    • Daugherty, A.1    Lu, H.2    Howatt, D.A.3
  • 64
    • 80053439792 scopus 로고    scopus 로고
    • Microfluidic Endothelial Cell Culture Model to Replicate Disturbed Flow Conditions Seen in Atherosclerosis Susceptible Regions
    • ,,, et al.. ;:-
    • Estrada R.,Giridharan G. A.,Nguyen M. D., et al.Microfluidic Endothelial Cell Culture Model to Replicate Disturbed Flow Conditions Seen in Atherosclerosis Susceptible Regions.Biomicrofluidics. 2011;5:32006-3200611
    • (2011) Biomicrofluidics , vol.5 , pp. 32006-3200611
    • Estrada, R.1    Giridharan, G.A.2    Nguyen, M.D.3
  • 65
    • 33244471087 scopus 로고    scopus 로고
    • Ag/AgCl Microelectrodes with Improved Stability for Microfluidics
    • ,,, et al.. ;:-
    • Brian J.,Polka A. S.,Mijares G., et al.Ag/AgCl Microelectrodes with Improved Stability for Microfluidics.Sens. Actuat. B. 2006;114:239-247
    • (2006) Sens. Actuat. B , vol.114 , pp. 239-247
    • Brian, J.1    Polka, A.S.2    Mijares, G.3
  • 66
    • 77949830370 scopus 로고    scopus 로고
    • Fabrication of Two-Layered Channel System with Embedded Electrodes to Measure Resistance across Epithelial and Endothelial Barriers
    • ,,, et al.. ;:-
    • Douville N. J.,Tung Y. C.,Li R., et al.Fabrication of Two-Layered Channel System with Embedded Electrodes to Measure Resistance across Epithelial and Endothelial Barriers.Anal. Chem. 2010;82:2505-2511
    • (2010) Anal. Chem , vol.82 , pp. 2505-2511
    • Douville, N.J.1    Tung, Y.C.2    Li, R.3
  • 67
    • 84871033897 scopus 로고    scopus 로고
    • Microfluidic Technologies for Accelerating the Clinical Translation of Nanoparticles
    • ,,, et al.. ;:-
    • Valencia P. M.,Farokhzad O. C.,Karnik R., et al.Microfluidic Technologies for Accelerating the Clinical Translation of Nanoparticles.Nat. Nanotechnol. 2012;7:623-629
    • (2012) Nat. Nanotechnol , vol.7 , pp. 623-629
    • Valencia, P.M.1    Farokhzad, O.C.2    Karnik, R.3
  • 68
  • 69
    • 84882252041 scopus 로고    scopus 로고
    • A Dynamic Multi-Organ-Chip for Long-Term Cultivation and Substance Testing Proven by 3D Human Liver and Skin Tissue Co-Culture
    • ,,, et al.. ;:-
    • Wagner I.,Materne E. M.,Brincker S., et al.A Dynamic Multi-Organ-Chip for Long-Term Cultivation and Substance Testing Proven by 3D Human Liver and Skin Tissue Co-Culture.Lab Chip. 2013;13:3538-3547
    • (2013) Lab Chip , vol.13 , pp. 3538-3547
    • Wagner, I.1    Materne, E.M.2    Brincker, S.3
  • 70
    • 84882247304 scopus 로고    scopus 로고
    • The Future of the Patient-Specific Body-on-a-Chip
    • ,,, et al.. ;:-
    • Williamson A.,Singh S.,Fernekorn U., et al.The Future of the Patient-Specific Body-on-a-Chip.Lab Chip. 2013;13:3471-3480
    • (2013) Lab Chip , vol.13 , pp. 3471-3480
    • Williamson, A.1    Singh, S.2    Fernekorn, U.3
  • 71
    • 84874894377 scopus 로고    scopus 로고
    • Microfabricated Mammalian Organ Systems and Their Integration into Models of Whole Animals and Humans
    • ,,, et al.. ;:-
    • Sung J. H.,Esch M. B.,Prot J. M., et al.Microfabricated Mammalian Organ Systems and Their Integration into Models of Whole Animals and Humans.Lab Chip. 2013;13:1201-1212
    • (2013) Lab Chip , vol.13 , pp. 1201-1212
    • Sung, J.H.1    Esch, M.B.2    Prot, J.M.3
  • 72
    • 84870293748 scopus 로고    scopus 로고
    • On Chip Porous Polymer Membranes for Integration of Gastrointestinal Tract Epithelium with Microfluidic ‘Body-on-a-Chip’ Devices
    • ,,, et al.. ;:-
    • Esch M. B.,Sung J. H.,Yang J., et al.On Chip Porous Polymer Membranes for Integration of Gastrointestinal Tract Epithelium with Microfluidic ‘Body-on-a-Chip’ Devices.Biomed. Microdevices. 2012;14:895-906
    • (2012) Biomed. Microdevices , vol.14 , pp. 895-906
    • Esch, M.B.1    Sung, J.H.2    Yang, J.3
  • 73
    • 84861482079 scopus 로고    scopus 로고
    • Muscle on a Chip: In Vitro Contractility Assays for Smooth and Striated Muscle
    • ,,, et al.. ;:-
    • Grosberg A.,Nesmith A. P.,Goss J. A., et al.Muscle on a Chip: In Vitro Contractility Assays for Smooth and Striated Muscle.J. Pharmacol. Toxicol. Methods. 2012;65:126-135
    • (2012) J. Pharmacol. Toxicol. Methods , vol.65 , pp. 126-135
    • Grosberg, A.1    Nesmith, A.P.2    Goss, J.A.3
  • 74
    • 77954038080 scopus 로고    scopus 로고
    • Reconstituting Organ-Level Lung Functions on a Chip
    • ,,, et al.. ;:-
    • Huh D.,Matthews B. D.,Mammoto A., et al.Reconstituting Organ-Level Lung Functions on a Chip.Science. 2010;328:1662-1668
    • (2010) Science , vol.328 , pp. 1662-1668
    • Huh, D.1    Matthews, B.D.2    Mammoto, A.3
  • 75
    • 84862207235 scopus 로고    scopus 로고
    • Human Gut-on-a-Chip Inhabited by Microbial Flora That Experiences Intestinal Peristalsis-Like Motions and Flow
    • ,,, et al.. ;:-
    • Kim H. J.,Huh D.,Hamilton G., et al.Human Gut-on-a-Chip Inhabited by Microbial Flora That Experiences Intestinal Peristalsis-Like Motions and Flow.Lab Chip. 2012;12:2165-2174
    • (2012) Lab Chip , vol.12 , pp. 2165-2174
    • Kim, H.J.1    Huh, D.2    Hamilton, G.3
  • 76
    • 82555202753 scopus 로고    scopus 로고
    • Imitation of Drug Metabolism in Human Liver and Cytotoxicity Assay Using a Microfluidic Device Coupled to Mass Spectrometric Detection
    • ,,, et al.. ;:-
    • Mao S.,Gao D.,Liu W., et al.Imitation of Drug Metabolism in Human Liver and Cytotoxicity Assay Using a Microfluidic Device Coupled to Mass Spectrometric Detection.Lab Chip. 2012;12:219-226
    • (2012) Lab Chip , vol.12 , pp. 219-226
    • Mao, S.1    Gao, D.2    Liu, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.