Transient blockade of ERK phosphorylation in the critical period causes autistic phenotypes as an adult in mice

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Yufune, Shinya ^a   Satoh, Yasushi ^a   Takamatsu, Isao ^a   Ohta, Hiroyuki ^a   Kobayashi, Yasushi ^a   Takaenoki, Yumiko ^a   Pagès, Gilles ^b   Pouysségur, Jacques ^b,c   Endo, Shogo ^d   Kazama, Tomiei ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b UNIVERSITY OF NICE SOPHIA ANTIPOLIS   (France)

^c CENTRE SCIENTIFIQUE DE MONACO   (Monaco)

^d Tokyo Metropolitan Institute of Gerontology   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ALPHA [AMINO(4 AMINOPHENYLTHIO)METHYLENE] 2 (TRIFLUOROMETHYL)PHENYLACETONITRILE; AMINOACETONITRILE; CASPASE 3; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N METHYLASPARTIC ACID;

ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; APOPTOSIS; AUTISM; C57BL MOUSE; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LONG TERM POTENTIATION; METABOLISM; MOUSE; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; AMINOACETONITRILE; ANIMALS; APOPTOSIS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; CASPASE 3; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LONG-TERM POTENTIATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; N-METHYLASPARTATE; PHENOTYPE; PHOSPHORYLATION; PROTEIN ISOFORMS;

EID: 84930226696     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10252     Document Type: Article

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