Effect of Rhizoma paridis total saponins on apoptosis of colorectal cancer cells and imbalance of the JAK/STAT3 molecular pathway induced by IL-6 suppression

Genetics and Molecular Research

Volumn 14, Issue 2, 2015, Pages 5793-5803

  Teng, W J ^a   Chen, P ^b   Zhu, F Y ^c   Di, K ^d   Zhou, C ^e   Zhuang, J ^e   Cao, X J ^a   Yang, J ^e   Deng, L J ^e   Sun, C G ^e  

^a SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Oncology Department of Changshu Hospital of Traditional Chinese Medicine   (China)

^c Medical Oncology Auxiliary Fuding Hospital Fujian Traditional Chinese Medicine University of Fujian Province   (China)

^d SECOND MILITARY MEDICAL UNIVERSITY   (China)

^e Weifang Traditional Chinese Medicine Hospital   (China)

Author keywords

Apoptosis; Colorectal cancer; IL 6 JAK STAT3 pathway; Rhizoma paridis total saponins (RPTS)

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 6; JANUS KINASE; SAPONIN; STAT3 PROTEIN; IL6 PROTEIN, HUMAN; PLANT EXTRACT; STAT3 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; CYTOKINE RELEASE; DISSOCIATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MORPHOLOGY; PARIS POLYPHYLLA; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; RHIZOME; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BIOSYNTHESIS; CHEMISTRY; COLORECTAL NEOPLASMS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; JANUS KINASES; PHOSPHORYLATION; PLANT EXTRACTS; SAPONINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84930216558     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2015.May.29.11     Document Type: Article

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