Intracellular self-assembly and disassembly of 19F nanoparticles confer respective "off" and "on" 19F NMR/MRI signals for legumain activity detection in zebrafish

ACS Nano

Volumn 9, Issue 5, 2015, Pages 5117-5124

  Yuan, Yue ^a   Ge, Shuchao ^a   Sun, Hongbin ^b   Dong, Xuejiao ^a   Zhao, Hongxin ^b   An, Linna ^a   Zhang, Jia ^a   Wang, Junfeng ^b   Hu, Bing ^a   Liang, Gaolin ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b HEFEI INSTITUTES OF PHYSICAL SCIENCE   (China)

Author keywords

19F MRI; disassembly; legumain; self assembly; zebrafish

Indexed keywords

DIAGNOSIS; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE; PROBES;

ACTIVITY DETECTION; CONTROLLED SELF-ASSEMBLY; DISASSEMBLY; GLUTATHIONES; HIGH INJECTION; HIGH SENSITIVITY; LEGUMAIN; ZEBRAFISH;

SELF ASSEMBLY;

CYSTEINE PROTEINASE; FLUORINE; GLUTATHIONE; LEGUMAIN; NANOPARTICLE;

ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG DESIGN; HEK293 CELL LINE; HUMAN; INTRACELLULAR SPACE; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; ZEBRA FISH;

ANIMALS; CYSTEINE ENDOPEPTIDASES; DRUG DESIGN; FLUORINE; GLUTATHIONE; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NANOPARTICLES; ZEBRAFISH;

EID: 84930216310     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b00287     Document Type: Article

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