Capillary isoelectric focusing method development and validation for investigation of recombinant therapeutic monoclonal antibody

Journal of Pharmaceutical and Biomedical Analysis

Volumn 114, Issue , 2015, Pages 53-61

  Suba, Dávid ^a   Urbányi, Zoltán ^a   Salgó, András ^b  

^a GEDEON RICHTER LTD   (Hungary)

^b BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

Author keywords

Capillary electrophoresis; Isoelectric focusing; Method development; Monoclonal antibody; Validation

Indexed keywords

MONOCLONAL ANTIBODY; PEPTIDE; PROTEIN; RECOMBINANT ANTIBODY; BUFFER; ELECTROLYTE; IMMUNOGLOBULIN G; INORGANIC SALT; ISOPROTEIN; RECOMBINANT PROTEIN; UREA;

ADSORPTION; ARTICLE; CALIBRATION; CAPILLARY ISOELECTRIC FOCUSING; CAPILLARY WALL; ISOELECTRIC POINT; PH; PRECIPITATION; PRIORITY JOURNAL; QUALITY CONTROL; CAPILLARY ELECTROPHORESIS; CHEMISTRY; ELECTRODE; EQUIPMENT DESIGN; HUMAN; ISOELECTRIC FOCUSING; PROCEDURES; REPRODUCIBILITY;

ANTIBODIES, MONOCLONAL; BUFFERS; CALIBRATION; ELECTRODES; ELECTROLYTES; ELECTROPHORESIS, CAPILLARY; EQUIPMENT DESIGN; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; ISOELECTRIC FOCUSING; ISOELECTRIC POINT; PROTEIN ISOFORMS; QUALITY CONTROL; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SALTS; UREA;

EID: 84930216206     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.04.037     Document Type: Article

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