Nanodiscs as a modular platform for multimodal MR-optical imaging

Bioconjugate Chemistry

Volumn 26, Issue 5, 2015, Pages 899-905

  Carney, Christiane E ^a   Lenov, Ivan L ^b   Baker, Catherine J ^b   Macrenaris, Keith W ^a   Eckermann, Amanda L ^a   Sligar, Stephen G ^b   Meade, Thomas J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM COMPOUNDS; LIPID BILAYERS; PHOSPHOLIPIDS; PROTEINS;

CONTRAST AGENT; DISCOIDAL PARTICLES; MEMBRANE PROTEINS; MODULAR PLATFORM; MONO-DISPERSE; MONOMERICS; MULTI-MODAL; MULTIMERIC; NANODISKS; SCAFFOLD PROTEIN;

SCAFFOLDS (BIOLOGY);

CONTRAST MEDIUM; GADOLINIUM; GADOTERIDOL; MEMBRANE PROTEIN; MONOMER; NANODISC; NANOPARTICLE; PHOSPHORYLCHOLINE; POLYMER; SCAFFOLD PROTEIN; TETRAMETHYLRHODAMINE; NANOMATERIAL; RHODAMINE;

ARTICLE; CELL FRACTIONATION; CELL LABELING; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG EFFECT; DRUG RETENTION; FLOW CYTOMETRY; FLUORESCENCE; HELA CELL LINE; LIPOPHILICITY; MCF 7 CELL LINE; NUCLEAR MAGNETIC RESONANCE IMAGING; CHEMICAL PHENOMENA; CHEMISTRY; CONFORMATION; FLUORESCENCE IMAGING; HUMAN; MCF-7 CELL LINE; MOLECULAR MODEL; MULTIMODAL IMAGING; PROCEDURES; SOLUBILITY;

CONTRAST MEDIA; GADOLINIUM; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETIC RESONANCE IMAGING; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MULTIMODAL IMAGING; NANOSTRUCTURES; OPTICAL IMAGING; RHODAMINES; SOLUBILITY;

EID: 84930211313     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.5b00107     Document Type: Article

References (36)

1. Modo, M., Beech, J. S., Meade, T. J., Williams, S. C. R., and Price, J. (2009) A chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke Neuroimage 47, T133-T142
2. Modo, M., Roberts, T., Sandhu, J., Brekke, C., Ashioti, M., Meade, T. J., Price, J., and Williams, S. C. R. (2004) In vivo detection of stem cells by magnetic resonance imaging Neurobiol. Aging 25, S19-S19
3. Ahrens, E. T. and Bulte, J. W. M. (2013) Tracking immune cells in vivo using magnetic resonance imaging Nat. Rev. Immunol. 13, 755-763
4. Weissleder, R. (2006) Molecular imaging in cancer Science 312, 1168-1171
5. Massoud, T. F. and Gambhir, S. S. (2003) Molecular imaging in living subjects: seeing fundamental biological processes in a new light Gene Dev. 17, 545-580
6. Louie, A. Y., Huber, M. M., Ahrens, E. T., Rothbacher, U., Moats, R., Jacobs, R. E., Fraser, S. E., and Meade, T. J. (2000) In vivo visualization of gene expression using magnetic resonance imaging Nat. Biotechnol. 18, 321-325
7. Keliris, A., Ziegler, T., Mishra, R., Pohmann, R., Sauer, M. G., Ugurbil, K., and Engelmann, J. (2011) Synthesis and characterization of a cell-permeable bimodal contrast agent targeting beta-galactosidase Bioorg. Med. Chem. 19, 2529-40
8. Sukerkar, P. A., MacRenaris, K. W., Meade, T. J., and Burdettes, J. E. (2011) A steroid-conjugated magnetic resonance probe enhances contrast in progesterone receptor expressing organs and tumors in vivo Mol. Pharmaceut. 8, 1390-1400
9. Sosnovik, D. E., Schellenberger, E. A., Nahrendorf, M., Novikov, M. S., Matsui, T., Dai, G., Reynolds, F., Grazette, L., Rosenzweig, A., and Weissleder, R. 2005, Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle Magn. Reson. Med. 54, 718-724
10. Winter, P. M., Caruthers, S. D., Yu, X., Song, S. K., Chen, J. J., Miller, B., Bulte, J. W. M., Robertson, J. D., Gaffney, P. J., and Wickline, S. A. 2003, Improved molecular imaging contrast agent for detection of human thrombus Magn. Reson. Med. 50, 411-416
11. Modo, M., Hoehn, M., and Bulte, J. W. M. (2005) Cellular MR imaging Mol. Imaging 4, 143-164
12. Caravan, P. (2006) Strategies for increasing the sensitivity of gadolinium based MRI contrast agents Chem. Soc. Rev. 35, 512-523
13. Helm, L., Merbach, A. E., and Tóth, E. (2013) The chemistry of contrast agents in medical magnetic resonance imaging, 2nd ed., John Wiley & Sons, New York.
14. Bruckman, M. A., Yu, X., and Steinmetz, N. F. (2013) Engineering Gd-loaded nanoparticles to enhance MRI sensitivity via T(1) shortening Nanotechnology 24, 462001
15. Song, Y., Xu, X., MacRenaris, K. W., Zhang, X. Q., Mirkin, C. A., and Meade, T. J. (2009) Multimodal gadolinium-enriched DNA-gold nanoparticle conjugates for cellular imaging Angew. Chem., Int. Ed. 48, 9143-7
16. Rieter, W. J., Kim, J. S., Taylor, K. M., An, H., Lin, W., Tarrant, T., and Lin, W. (2007) Hybrid silica nanoparticles for multimodal imaging Angew. Chem., Int. Ed. 46, 3680-2
17. Qin, H., Zhou, T., Yang, S. H., Chen, Q., and Xing, D. (2013) Gadolinium(III)-gold nanorods for MRI and photoacoustic imaging dual-modality detection of macrophages in atherosclerotic inflammation Nanomedicine (London, U.K.) 8, 1611-1624
18. Sabella, S., Carney, R. P., Brunetti, V., Malvindi, M. A., Al-Juffali, N., Vecchio, G., Janes, S. M., Bakr, O. M., Cingolani, R., and Stellacci, F. 2014, A general mechanism for intracellular toxicity of metal-containing nanoparticles Nanoscale 6, 7052-61
19. Manke, A., Wang, L., and Rojanasakul, Y. (2013) Mechanisms of nanoparticle-induced oxidative stress and toxicity BioMed. Res. Int. 2013, 942916
20. Schrand, A. M., Rahman, M. F., Hussain, S. M., Schlager, J. J., Smith, D. A., and Syed, A. F. (2010) Metal-based nanoparticles and their toxicity assessment Wiley Interdiscip. Rev.: Nanomed. Nanobiotechnol. 2, 544-68
21. Langereis, S., Geelen, T., Grull, H., Strijkers, G. J., and Nicolay, K. (2013) Paramagnetic liposomes for molecular MRI and MRI-guided drug delivery NMR Biomed. 26, 728-44
22. Mulder, W. J., Strijkers, G. J., van Tilborg, G. A., Griffioen, A. W., and Nicolay, K. (2006) Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging NMR Biomed. 19, 142-64
23. Cormode, D. P., Frias, J. C., Ma, Y. Q., Chen, W., Skajaa, T., Briley-Saebo, K., Barazza, A., Williams, K. J., Mulder, W. J. M., and Fayad, Z. A. 2009, HDL as a contrast agent for medical imaging Clin. Lipidol. 4, 493-500
24. Mulder, W. J. M., Strijkers, G. J., Griffioen, A. W., van Bloois, L., Molema, G., Storm, G., Koning, G. A., and Nicolay, K. (2004) A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets Bioconjugate Chem. 15, 799-806
25. Kamaly, N., Kalber, T., Kenny, G., Bell, J., Jorgensen, M., and Miller, A. (2010) A novel bimodal lipidic contrast agent for cellular labelling and tumour MRI Org. Biomol. Chem. 8, 201-211
26. Chen, W., Vucic, E., Leupold, E., Mulder, W. J. M., Cormode, D. P., Briley-Saebo, K. C., Barazza, A., Fisher, E. A., Dathe, M., and Fayad, Z. A. (2008) Incorporation of an apoE-derived lipopeptide in high-density lipoprotein MRI contrast agents for enhanced imaging of macrophages in atherosclerosis Contrast Media Mol. Imaging 3, 233-242
27. Kleinschmidt, J. H. (2013) Lipid-protein interactions: methods and protocols, Springer, New York.
28. Denisov, I. G., Grinkova, Y. V., Lazarides, A. A., and Sligar, S. G. (2004) Directed self-assembly of monodisperse phospholipid bilayer nanodiscs with controlled size J. Am. Chem. Soc. 126, 3477-3487
29. Bayburt, T. H., Grinkova, Y. V., and Sligar, S. G. (2002) Self-assembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins Nano Lett. 2, 853-856
30. Nath, A., Atkins, W. M., and Sligar, S. G. (2007) Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins Biochemistry 46, 2059-2069
31. Numata, M., Grinkova, Y. V., Mitchell, J. R., Chu, H. W., Sligar, S. G., and Voelker, D. R. (2013) Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung Int. J. Nanomed. 8, 1417-1427
32. Carney, C. E., MacRenaris, K. W., Mastarone, D. J., Kasjanski, D. R., Hung, A. H., and Meade, T. J. (2014) Cell labeling via membrane-anchored lipophilic MR contrast agents Bioconjugate Chem. 25, 945-954
33. Song, Y., Kohlmeir, E. K., and Meade, T. J. (2008) Synthesis of multimeric MR contrast agents for cellular imaging J. Am. Chem. Soc. 130, 6662-+
34. Song, Y., Xu, X. Y., MacRenaris, K. W., Zhang, X. Q., Mirkin, C. A., and Meade, T. J. (2009) Multimodal gadolinium-enriched DNA-gold nanoparticle conjugates for cellular imaging Angew. Chem., Int. Ed. 48, 9143-9147
35. Brekke, C., Morgan, S. C., Lowe, A. S., Meade, T. J., Price, J., Williams, S. C. R., and Modo, M. (2007) The in vitro effects of a bimodal contrast agent on cellular functions and relaxometry NMR Biomed. 20, 77-89
36. Li, H. R., Sun, S. Y., Salim, T., Bomma, S., Grimsdale, A. C., and Lam, Y. M. (2012) Conjugated polymers based on dicarboxylic imide-substituted isothianaphthene and their applications in solar cells J. Polym. Sci.: Polym. Chem. 50, 250-260