메뉴 건너뛰기




Volumn 75, Issue 8, 2015, Pages 847-858

The expanding role of somatostatin analogs in gastroenteropancreatic and lung neuroendocrine tumors

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPEPTIN; OCTREOTIDE; PASIREOTIDE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; CYCLOPEPTIDE; SOMATOSTATIN;

EID: 84930182341     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-015-0397-7     Document Type: Review
Times cited : (42)

References (105)
  • 1
    • 0000260146 scopus 로고
    • Karzinoide Tumoren des Dünndarms
    • Oberndorfer S. Karzinoide Tumoren des Dünndarms. Frankf Z Pathol. 1907;1:425-9.
    • (1907) Frankf Z Pathol. , vol.1 , pp. 425-429
    • Oberndorfer, S.1
  • 2
    • 33846444742 scopus 로고    scopus 로고
    • Evolution of the diffuse neuroendocrine system: Clear cells and cloudy origins
    • 1:CAS:528:DC%2BD2sXjsFOltQ%3D%3D 17106184
    • Modlin IM, Champaneria MC, Bornschein J, et al. Evolution of the diffuse neuroendocrine system: clear cells and cloudy origins. Neuroendocrinology. 2006;84(2):69-82.
    • (2006) Neuroendocrinology , vol.84 , Issue.2 , pp. 69-82
    • Modlin, I.M.1    Champaneria, M.C.2    Bornschein, J.3
  • 4
    • 84907228763 scopus 로고    scopus 로고
    • An update on gastroenteropancreatic neuroendocrine tumors
    • Cives M, Strosberg J. An update on gastroenteropancreatic neuroendocrine tumors. Oncology (Williston Park). 2014;28(9):749-56.
    • (2014) Oncology (Williston Park). , vol.28 , Issue.9 , pp. 749-756
    • Cives, M.1    Strosberg, J.2
  • 5
    • 45849126916 scopus 로고    scopus 로고
    • Pancreatic endocrine neoplasms: Epidemiology and prognosis of pancreatic endocrine tumors
    • 2693313 18508996
    • Halfdanarson TR, Rubin J, Farnell MB, Grant CS, Petersen GM. Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors. Endocr Relat Cancer. 2008;15(2):409-27.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.2 , pp. 409-427
    • Halfdanarson, T.R.1    Rubin, J.2    Farnell, M.B.3    Grant, C.S.4    Petersen, G.M.5
  • 6
    • 79956152733 scopus 로고    scopus 로고
    • Nomenclature and classification of neuroendocrine neoplasms of the digestive system
    • Bosman TF, Carneiro F, Hruban RH, Theise ND, editors 4th ed. Lyon: International Agency for Research on cancer (IARC)
    • Rindi G, Arnold R, Bosman FT, et al. Nomenclature and classification of neuroendocrine neoplasms of the digestive system. In: Bosman TF, Carneiro F, Hruban RH, Theise ND, editors. WHO classification of tumours of the digestive system. 4th ed. Lyon: International Agency for Research on cancer (IARC); 2010. p. 13.
    • (2010) WHO Classification of Tumours of the Digestive System , pp. 13
    • Rindi, G.1    Arnold, R.2    Bosman, F.T.3
  • 8
    • 84874773590 scopus 로고    scopus 로고
    • Prognostic validity of the American Joint Committee on Cancer staging classification for midgut neuroendocrine tumors
    • 23248248
    • Strosberg JR, Weber JM, Feldman M, Coppola D, Meredith K, Kvols LK. Prognostic validity of the American Joint Committee on Cancer staging classification for midgut neuroendocrine tumors. J Clin Oncol. 2013;31(4):420-5.
    • (2013) J Clin Oncol , vol.31 , Issue.4 , pp. 420-425
    • Strosberg, J.R.1    Weber, J.M.2    Feldman, M.3    Coppola, D.4    Meredith, K.5    Kvols, L.K.6
  • 9
    • 80051619926 scopus 로고    scopus 로고
    • Prognostic validity of a novel American Joint Committee on Cancer Staging Classification for pancreatic neuroendocrine tumors
    • 21709192
    • Strosberg JR, Cheema A, Weber J, Han G, Coppola D, Kvols LK. Prognostic validity of a novel American Joint Committee on Cancer Staging Classification for pancreatic neuroendocrine tumors. J Clin Oncol. 2011;29(22):3044-9.
    • (2011) J Clin Oncol , vol.29 , Issue.22 , pp. 3044-3049
    • Strosberg, J.R.1    Cheema, A.2    Weber, J.3    Han, G.4    Coppola, D.5    Kvols, L.K.6
  • 11
    • 77955834798 scopus 로고    scopus 로고
    • Biological characteristics and treatment outcomes of metastatic or recurrent neuroendocrine tumors: Tumor grade and metastatic site are important for treatment strategy
    • 2936327 20731845
    • Kim SJ, Kim JW, Han SW, Oh DY, Lee SH, Kim DW, Im SA, Kim TY, Seog Heo D, Bang YJ. Biological characteristics and treatment outcomes of metastatic or recurrent neuroendocrine tumors: tumor grade and metastatic site are important for treatment strategy. BMC Cancer. 2010;10:448.
    • (2010) BMC Cancer , vol.10 , pp. 448
    • Kim, S.J.1    Kim, J.W.2    Han, S.W.3    Oh, D.Y.4    Lee, S.H.5    Kim, D.W.6    Im, S.A.7    Kim, T.Y.8    Seog Heo, D.9    Bang, Y.J.10
  • 14
    • 0022510433 scopus 로고
    • Treatment of the malignant carcinoid syndrome. Evaluation of a long-acting somatostatin analogue
    • 1:STN:280:DyaL28zhtFSrsQ%3D%3D 2427948
    • Kvols LK, Moertel CG, O'Connell MJ, Schutt AJ, Rubin J, Hahn RG. Treatment of the malignant carcinoid syndrome. Evaluation of a long-acting somatostatin analogue. N Engl J Med. 1986;315:663-6.
    • (1986) N Engl J Med , vol.315 , pp. 663-666
    • Kvols, L.K.1    Moertel, C.G.2    O'Connell, M.J.3    Schutt, A.J.4    Rubin, J.5    Hahn, R.G.6
  • 15
    • 70350442637 scopus 로고    scopus 로고
    • Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: A report from the PROMID Study Group
    • PROMID Study Group 1:CAS:528:DC%2BD1MXhtlGgtbnJ 19704057
    • Rinke A, Müller HH, Schade-Brittinger C, Klose KJ, Barth P, Wied M, Mayer C, Aminossadati B, Pape UF, Bläker M, Harder J, Arnold C, Gress T, Arnold R, PROMID Study Group. Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: a report from the PROMID Study Group. J Clin Oncol. 2009;27(28):4656-63.
    • (2009) J Clin Oncol , vol.27 , Issue.28 , pp. 4656-4663
    • Rinke, A.1    Müller, H.H.2    Schade-Brittinger, C.3    Klose, K.J.4    Barth, P.5    Wied, M.6    Mayer, C.7    Aminossadati, B.8    Pape, U.F.9    Bläker, M.10    Harder, J.11    Arnold, C.12    Gress, T.13    Arnold, R.14
  • 17
    • 0015914428 scopus 로고
    • Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone
    • 1:CAS:528:DyaE3sXnvF2ksA%3D%3D 4682131
    • Brazeau P, Vale W, Burgus R, Ling N, Butcher M, Rivier J, Guillemin R. Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science. 1973;179(4068):77-9.
    • (1973) Science , vol.179 , Issue.4068 , pp. 77-79
    • Brazeau, P.1    Vale, W.2    Burgus, R.3    Ling, N.4    Butcher, M.5    Rivier, J.6    Guillemin, R.7
  • 18
    • 0027818856 scopus 로고
    • Somatostatin analogs for diagnosis and treatment of cancer
    • 1:CAS:528:DyaK2cXis1Wntro%3D 7912834
    • Weckbecker G, Raulf F, Stolz B, Bruns C. Somatostatin analogs for diagnosis and treatment of cancer. Pharmacol Ther. 1993;60(2):245-64.
    • (1993) Pharmacol Ther , vol.60 , Issue.2 , pp. 245-264
    • Weckbecker, G.1    Raulf, F.2    Stolz, B.3    Bruns, C.4
  • 19
    • 0026028156 scopus 로고
    • Somatostatin and analogues in the treatment of cancer. A review
    • 1358326 1:STN:280:DyaK3M7ltFWnuw%3D%3D 1671812
    • Evers BM, Parekh D, Townsend CM Jr, Thompson JC. Somatostatin and analogues in the treatment of cancer. A review. Ann Surg. 1991;213(3):190-8.
    • (1991) Ann Surg. , vol.213 , Issue.3 , pp. 190-198
    • Evers, B.M.1    Parekh, D.2    Townsend, Jr.C.M.3    Thompson, J.C.4
  • 20
    • 0035084694 scopus 로고    scopus 로고
    • Antiproliferative effect of somatostatin and analogs
    • 1:CAS:528:DC%2BD3MXit12ltb4%3D 11275700
    • Bousquet C, Puente E, Buscail L, Vaysse N, Susini C. Antiproliferative effect of somatostatin and analogs. Chemotherapy. 2001;47(Suppl 2):30-9.
    • (2001) Chemotherapy. , vol.47 , pp. 30-39
    • Bousquet, C.1    Puente, E.2    Buscail, L.3    Vaysse, N.4    Susini, C.5
  • 21
    • 0018681487 scopus 로고
    • Somatostatin cell processes as pathways for paracrine secretion
    • 1:CAS:528:DyaE1MXlslaltbg%3D 382360
    • Larsson LI, Goltermann N, de Magistris L, Rehfeld JF, Schwartz TW. Somatostatin cell processes as pathways for paracrine secretion. Science. 1979;205(4413):1393-5.
    • (1979) Science , vol.205 , Issue.4413 , pp. 1393-1395
    • Larsson, L.I.1    Goltermann, N.2    De Magistris, L.3    Rehfeld, J.F.4    Schwartz, T.W.5
  • 24
    • 84925581799 scopus 로고    scopus 로고
    • Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy
    • 20637207
    • Oberg KE, Reubi JC, Kwekkeboom DJ, Krenning EP. Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy. Gastroenterology. 2010;139(3):742-53.
    • (2010) Gastroenterology , vol.139 , Issue.3 , pp. 742-753
    • Oberg, K.E.1    Reubi, J.C.2    Kwekkeboom, D.J.3    Krenning, E.P.4
  • 27
    • 72949085528 scopus 로고    scopus 로고
    • Review article: Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours
    • 1:CAS:528:DC%2BC3cXhtlOgs7c%3D 19845567
    • Modlin IM, Pavel M, Kidd M, Gustafsson BI. Review article: somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours. Aliment Pharmacol Ther. 2010;31(2):169-88.
    • (2010) Aliment Pharmacol Ther , vol.31 , Issue.2 , pp. 169-188
    • Modlin, I.M.1    Pavel, M.2    Kidd, M.3    Gustafsson, B.I.4
  • 28
    • 0036271475 scopus 로고    scopus 로고
    • Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis
    • 1:CAS:528:DC%2BD38Xjs1yhsLc%3D 12021920
    • Papotti M, Bongiovanni M, Volante M, Allìa E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G. Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis. Virchows Arch. 2002;440(5):461-75.
    • (2002) Virchows Arch , vol.440 , Issue.5 , pp. 461-475
    • Papotti, M.1    Bongiovanni, M.2    Volante, M.3    Allìa, E.4    Landolfi, S.5    Helboe, L.6    Schindler, M.7    Cole, S.L.8    Bussolati, G.9
  • 29
    • 84924973406 scopus 로고    scopus 로고
    • Somatostatin receptors in bronchopulmonary neuroendocrine neoplasms: New diagnostic, prognostic, and therapeutic markers
    • 1:CAS:528:DC%2BC2MXlvVGisbk%3D 25494861
    • Kaemmerer D, Specht E, Sänger J, Wirtz RM, Sayeg M, Schulz S, Lupp A. Somatostatin receptors in bronchopulmonary neuroendocrine neoplasms: new diagnostic, prognostic, and therapeutic markers. J Clin Endocrinol Metab. 2015;100(3):831-40.
    • (2015) J Clin Endocrinol Metab , vol.100 , Issue.3 , pp. 831-840
    • Kaemmerer, D.1    Specht, E.2    Sänger, J.3    Wirtz, R.M.4    Sayeg, M.5    Schulz, S.6    Lupp, A.7
  • 30
    • 0020363575 scopus 로고
    • SMS 201-995: A very potent and selective octapeptide analogue of somatostatin with prolonged action
    • 1:CAS:528:DyaL38XlslGhtLg%3D 6128648
    • Bauer W, Briner U, Doepfner W, Haller R, Huguenin R, Marbach P, Petcher TJ, Pless. SMS 201-995: a very potent and selective octapeptide analogue of somatostatin with prolonged action. Life Sci. 1982;31(11):1133-40.
    • (1982) Life Sci , vol.31 , Issue.11 , pp. 1133-1140
    • Bauer, W.1    Briner, U.2    Doepfner, W.3    Haller, R.4    Huguenin, R.5    Marbach, P.6    Petcher, T.J.7    Pless8
  • 31
    • 6044221565 scopus 로고    scopus 로고
    • Functional activity of the multiligand analog SOM230 at human recombinant somatostatin receptor subtypes supports its usefulness in neuroendocrine tumors
    • 1:CAS:528:DC%2BD2cXotlahtb8%3D 15477717
    • Schmid HA, Schoeffter P. Functional activity of the multiligand analog SOM230 at human recombinant somatostatin receptor subtypes supports its usefulness in neuroendocrine tumors. Neuroendocrinology. 2004;80(Suppl 1):47-50.
    • (2004) Neuroendocrinology , vol.80 , pp. 47-50
    • Schmid, H.A.1    Schoeffter, P.2
  • 32
    • 43549111835 scopus 로고    scopus 로고
    • Pasireotide (SOM230): Development, mechanism of action and potential applications
    • 1:CAS:528:DC%2BD1cXmtVSmtbs%3D 17977644
    • Schmid HA. Pasireotide (SOM230): development, mechanism of action and potential applications. Mol Cell Endocrinol. 2008;286(1-2):69-74.
    • (2008) Mol Cell Endocrinol , vol.286 , Issue.1-2 , pp. 69-74
    • Schmid, H.A.1
  • 34
    • 77954556448 scopus 로고    scopus 로고
    • Antiproliferative effect of somatostatin analogs in gastroenteropancreatic neuroendocrine tumors
    • 2890935 1:CAS:528:DC%2BC3cXotlKjtbs%3D 20572298
    • Strosberg J, Kvols L. Antiproliferative effect of somatostatin analogs in gastroenteropancreatic neuroendocrine tumors. World J Gastroenterol. 2010;16(24):2963-70.
    • (2010) World J Gastroenterol , vol.16 , Issue.24 , pp. 2963-2970
    • Strosberg, J.1    Kvols, L.2
  • 35
    • 0033053184 scopus 로고    scopus 로고
    • Octreotide acetate long-acting formulation versus open-label subcutaneous octreotide acetate in malignant carcinoid syndrome
    • 1:CAS:528:DyaK1MXht1Wmu7s%3D 10080605
    • Rubin J, Ajani J, Schirmer W, Venook AP, Bukowski R, Pommier R, Saltz L, Dandona P, Anthony L. Octreotide acetate long-acting formulation versus open-label subcutaneous octreotide acetate in malignant carcinoid syndrome. J Clin Oncol. 1999;17(2):600-6.
    • (1999) J Clin Oncol , vol.17 , Issue.2 , pp. 600-606
    • Rubin, J.1    Ajani, J.2    Schirmer, W.3    Venook, A.P.4    Bukowski, R.5    Pommier, R.6    Saltz, L.7    Dandona, P.8    Anthony, L.9
  • 36
    • 84921511812 scopus 로고    scopus 로고
    • Role of somatostatin analogues in the treatment of neuroendocrine tumors
    • 1:CAS:528:DC%2BC2MXisVOnsrY%3D 25583773
    • Narayanan S, Kunz PL. Role of somatostatin analogues in the treatment of neuroendocrine tumors. J Natl Compr Canc Netw. 2015;13(1):109-17.
    • (2015) J Natl Compr Canc Netw , vol.13 , Issue.1 , pp. 109-117
    • Narayanan, S.1    Kunz, P.L.2
  • 37
    • 0034651708 scopus 로고    scopus 로고
    • Treatment of carcinoid syndrome: A prospective crossover evaluation of lanreotide versus octreotide in terms of efficacy, patient acceptability, and tolerance
    • 10679645
    • O'Toole D, Ducreux M, Bommelaer G, Wemeau JL, Bouché O, Catus F, Blumberg J, Ruszniewski P. Treatment of carcinoid syndrome: a prospective crossover evaluation of lanreotide versus octreotide in terms of efficacy, patient acceptability, and tolerance. Cancer. 2000;88(4):770-6.
    • (2000) Cancer , vol.88 , Issue.4 , pp. 770-776
    • O'Toole, D.1    Ducreux, M.2    Bommelaer, G.3    Wemeau, J.L.4    Bouché, O.5    Catus, F.6    Blumberg, J.7    Ruszniewski, P.8
  • 38
    • 0036111856 scopus 로고    scopus 로고
    • SOM230: A novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile
    • 1:CAS:528:DC%2BD38XktFGitr4%3D 11980628
    • Bruns C, Lewis I, Briner U, Meno-Tetang G, Weckbecker G. SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur J Endocrinol. 2002;146(5):707-16.
    • (2002) Eur J Endocrinol , vol.146 , Issue.5 , pp. 707-716
    • Bruns, C.1    Lewis, I.2    Briner, U.3    Meno-Tetang, G.4    Weckbecker, G.5
  • 39
    • 84881316265 scopus 로고    scopus 로고
    • Hyperglycemia associated with pasireotide: Results from a mechanistic study in healthy volunteers
    • 1:CAS:528:DC%2BC3sXht12gsLfM 23733372
    • Henry RR, Ciaraldi TP, Armstrong D, Burke P, Ligueros-Saylan M, Mudaliar S. Hyperglycemia associated with pasireotide: results from a mechanistic study in healthy volunteers. J Clin Endocrinol Metab. 2013;98(8):3446-53.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.8 , pp. 3446-3453
    • Henry, R.R.1    Ciaraldi, T.P.2    Armstrong, D.3    Burke, P.4    Ligueros-Saylan, M.5    Mudaliar, S.6
  • 41
    • 84873385177 scopus 로고    scopus 로고
    • Update on the role of somatostatin analogs for the treatment of patients with gastroenteropancreatic neuroendocrine tumors
    • 1:CAS:528:DC%2BC3sXitFeqs74%3D 23391113
    • Toumpanakis C, Caplin ME. Update on the role of somatostatin analogs for the treatment of patients with gastroenteropancreatic neuroendocrine tumors. Semin Oncol. 2013;40(1):56-68.
    • (2013) Semin Oncol , vol.40 , Issue.1 , pp. 56-68
    • Toumpanakis, C.1    Caplin, M.E.2
  • 43
    • 84858055749 scopus 로고    scopus 로고
    • Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy
    • 1:CAS:528:DC%2BC38Xkt1ynsbg%3D 22170729
    • Bousquet C, Lasfargues C, Chalabi M, Billah SM, Susini C, Vezzosi D, Caron P, Pyronnet S. Clinical review: current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy. J Clin Endocrinol Metab. 2012;97(3):727-37.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.3 , pp. 727-737
    • Bousquet, C.1    Lasfargues, C.2    Chalabi, M.3    Billah, S.M.4    Susini, C.5    Vezzosi, D.6    Caron, P.7    Pyronnet, S.8
  • 44
    • 84857019757 scopus 로고    scopus 로고
    • GPCR mediated regulation of synaptic transmission
    • 3319362 1:CAS:528:DC%2BC38XktlensLg%3D 22307060
    • Betke KM, Wells CA, Hamm HE. GPCR mediated regulation of synaptic transmission. Prog Neurobiol. 2012;96(3):304-21.
    • (2012) Prog Neurobiol , vol.96 , Issue.3 , pp. 304-321
    • Betke, K.M.1    Wells, C.A.2    Hamm, H.E.3
  • 45
    • 0346328229 scopus 로고    scopus 로고
    • Opportunities in somatostatin research: Biological, chemical and therapeutic aspects
    • 1:CAS:528:DC%2BD3sXpvFCgtrs%3D 14654798
    • Weckbecker G, Lewis I, Albert R, Schmid HA, Hoyer D, Bruns C. Opportunities in somatostatin research: biological, chemical and therapeutic aspects. Nat Rev Drug Discov. 2003;2(12):999-1017.
    • (2003) Nat Rev Drug Discov. , vol.2 , Issue.12 , pp. 999-1017
    • Weckbecker, G.1    Lewis, I.2    Albert, R.3    Schmid, H.A.4    Hoyer, D.5    Bruns, C.6
  • 46
    • 0026573854 scopus 로고
    • Octreotide inhibits insulin-like growth factor-I hepatic gene expression in the hypophysectomized rat: Evidence for a direct and indirect mechanism of action
    • 1:CAS:528:DyaK38XitVymtbg%3D 1547711
    • Serri O, Brazeau P, Kachra Z, Posner B. Octreotide inhibits insulin-like growth factor-I hepatic gene expression in the hypophysectomized rat: evidence for a direct and indirect mechanism of action. Endocrinology. 1992;130(4):1816-21.
    • (1992) Endocrinology , vol.130 , Issue.4 , pp. 1816-1821
    • Serri, O.1    Brazeau, P.2    Kachra, Z.3    Posner, B.4
  • 47
    • 0037388747 scopus 로고    scopus 로고
    • Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities
    • 1:CAS:528:DC%2BD3sXisVegt78%3D 12639942
    • Florio T, Morini M, Villa V, Arena S, Corsaro A, Thellung S, Culler MD, Pfeffer U, Noonan DM, Schettini G, Albini A. Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities. Endocrinology. 2003;144(4):1574-84.
    • (2003) Endocrinology , vol.144 , Issue.4 , pp. 1574-1584
    • Florio, T.1    Morini, M.2    Villa, V.3    Arena, S.4    Corsaro, A.5    Thellung, S.6    Culler, M.D.7    Pfeffer, U.8    Noonan, D.M.9    Schettini, G.10    Albini, A.11
  • 50
    • 50449108845 scopus 로고    scopus 로고
    • Somatostatin receptors 1, 2, and 5 cooperate in the somatostatin inhibition of C6 glioma cell proliferation in vitro via a phosphotyrosine phosphatase-eta-dependent inhibition of extracellularly regulated kinase-1/2
    • 1:CAS:528:DC%2BD1cXhtVKmsr7K 18566118
    • Barbieri F, Pattarozzi A, Gatti M, Porcile C, Bajetto A, Ferrari A, Culler MD, Florio T. Somatostatin receptors 1, 2, and 5 cooperate in the somatostatin inhibition of C6 glioma cell proliferation in vitro via a phosphotyrosine phosphatase-eta-dependent inhibition of extracellularly regulated kinase-1/2. Endocrinology. 2008;149(9):4736-46.
    • (2008) Endocrinology , vol.149 , Issue.9 , pp. 4736-4746
    • Barbieri, F.1    Pattarozzi, A.2    Gatti, M.3    Porcile, C.4    Bajetto, A.5    Ferrari, A.6    Culler, M.D.7    Florio, T.8
  • 51
    • 0032549589 scopus 로고    scopus 로고
    • Sst2 somatostatin receptor mediates negative regulation of insulin receptor signaling through the tyrosine phosphatase SHP-1
    • 1:CAS:528:DyaK1cXitVGgurk%3D 9507021
    • Bousquet C, Delesque N, Lopez F, Saint-Laurent N, Estève JP, Bedecs K, Buscail L, Vaysse N, Susini C. sst2 somatostatin receptor mediates negative regulation of insulin receptor signaling through the tyrosine phosphatase SHP-1. J Biol Chem. 1998;273(12):7099-106.
    • (1998) J Biol Chem , vol.273 , Issue.12 , pp. 7099-7106
    • Bousquet, C.1    Delesque, N.2    Lopez, F.3    Saint-Laurent, N.4    Estève, J.P.5    Bedecs, K.6    Buscail, L.7    Vaysse, N.8    Susini, C.9
  • 52
    • 0035910930 scopus 로고    scopus 로고
    • Influence of the somatostatin receptor sst2 on growth factor signal cascades in human glioma cells
    • 1:CAS:528:DC%2BD3MXht12nsLg%3D 11223155
    • Held-Feindt J, Forstreuter F, Pufe T, Mentlein R. Influence of the somatostatin receptor sst2 on growth factor signal cascades in human glioma cells. Brain Res Mol Brain Res. 2001;87(1):12-21.
    • (2001) Brain Res Mol Brain Res , vol.87 , Issue.1 , pp. 12-21
    • Held-Feindt, J.1    Forstreuter, F.2    Pufe, T.3    Mentlein, R.4
  • 54
    • 18144377787 scopus 로고    scopus 로고
    • Restoration of functional gap junctions through internal ribosome entry site-dependent synthesis of endogenous connexins in density-inhibited cancer cells
    • 1087721 1:CAS:528:DC%2BD2MXktlSmu74%3D 15870276
    • Lahlou H, Fanjul M, Pradayrol L, Susini C, Pyronnet S. Restoration of functional gap junctions through internal ribosome entry site-dependent synthesis of endogenous connexins in density-inhibited cancer cells. Mol Cell Biol. 2005;25(10):4034-45.
    • (2005) Mol Cell Biol , vol.25 , Issue.10 , pp. 4034-4045
    • Lahlou, H.1    Fanjul, M.2    Pradayrol, L.3    Susini, C.4    Pyronnet, S.5
  • 55
    • 4043058143 scopus 로고    scopus 로고
    • Central and peripheral actions of somatostatin on the growth hormone-IGF-I axis
    • 484973 1:CAS:528:DC%2BD2cXmtlynsrg%3D 15286801
    • Murray RD, Kim K, Ren SG, Chelly M, Umehara Y, Melmed S. Central and peripheral actions of somatostatin on the growth hormone-IGF-I axis. J Clin Invest. 2004;114(3):349-56.
    • (2004) J Clin Invest. , vol.114 , Issue.3 , pp. 349-356
    • Murray, R.D.1    Kim, K.2    Ren, S.G.3    Chelly, M.4    Umehara, Y.5    Melmed, S.6
  • 57
    • 11244289595 scopus 로고    scopus 로고
    • Somatostatin receptor subtype-dependent regulation of nitric oxide release: Involvement of different intracellular pathways
    • 1:CAS:528:DC%2BD2MXjtVersw%3D%3D 15388796
    • Arena S, Pattarozzi A, Corsaro A, Schettini G, Florio T. Somatostatin receptor subtype-dependent regulation of nitric oxide release: involvement of different intracellular pathways. Mol Endocrinol. 2005;19(1):255-67.
    • (2005) Mol Endocrinol , vol.19 , Issue.1 , pp. 255-267
    • Arena, S.1    Pattarozzi, A.2    Corsaro, A.3    Schettini, G.4    Florio, T.5
  • 58
    • 8844254688 scopus 로고    scopus 로고
    • Anti-angiogenic effects of somatostatin receptor subtype 2 on human pancreatic cancer xenografts
    • 1:CAS:528:DC%2BD2cXhtVWgs7zM 15205362
    • Kumar M, Liu ZR, Thapa L, Qin RY. Anti-angiogenic effects of somatostatin receptor subtype 2 on human pancreatic cancer xenografts. Carcinogenesis. 2004;25(11):2075-81.
    • (2004) Carcinogenesis , vol.25 , Issue.11 , pp. 2075-2081
    • Kumar, M.1    Liu, Z.R.2    Thapa, L.3    Qin, R.Y.4
  • 59
    • 0029791822 scopus 로고    scopus 로고
    • Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5): Subtype selective internalization or upregulation
    • 1:CAS:528:DyaK28Xlt1KhsbY%3D 8756582
    • Hukovic N, Panetta R, Kumar U, Patel YC. Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5): subtype selective internalization or upregulation. Endocrinology. 1996;137(9):4046-9.
    • (1996) Endocrinology. , vol.137 , Issue.9 , pp. 4046-4049
    • Hukovic, N.1    Panetta, R.2    Kumar, U.3    Patel, Y.C.4
  • 60
    • 2442705543 scopus 로고    scopus 로고
    • Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes
    • 1:CAS:528:DC%2BD2cXjvV2nurk%3D 15001578
    • Tulipano G, Stumm R, Pfeiffer M, Kreienkamp HJ, Höllt V, Schulz S. Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes. J Biol Chem. 2004;279(20):21374-82.
    • (2004) J Biol Chem , vol.279 , Issue.20 , pp. 21374-21382
    • Tulipano, G.1    Stumm, R.2    Pfeiffer, M.3    Kreienkamp, H.J.4    Höllt, V.5    Schulz, S.6
  • 61
    • 43549108318 scopus 로고    scopus 로고
    • Selective agonism in somatostatin receptor signaling and regulation
    • 2435097 1:CAS:528:DC%2BD1cXmtVSmtLc%3D 18006219
    • Schonbrunn A. Selective agonism in somatostatin receptor signaling and regulation. Mol Cell Endocrinol. 2008;286(1-2):35-9.
    • (2008) Mol Cell Endocrinol , vol.286 , Issue.1-2 , pp. 35-39
    • Schonbrunn, A.1
  • 62
    • 84889084502 scopus 로고    scopus 로고
    • Illuminating somatostatin analog action at neuroendocrine tumor receptors
    • 1:CAS:528:DC%2BC3sXhslWmt7zF 24183675
    • Reubi JC, Schonbrunn A. Illuminating somatostatin analog action at neuroendocrine tumor receptors. Trends Pharmacol Sci. 2013;34(12):676-88.
    • (2013) Trends Pharmacol Sci , vol.34 , Issue.12 , pp. 676-688
    • Reubi, J.C.1    Schonbrunn, A.2
  • 63
    • 13344295073 scopus 로고    scopus 로고
    • Clinical efficacy of octreotide in the treatment of metastatic neuroendocrine tumors. A study by the Italian Trials in Medical Oncology Group
    • 8625251
    • di Bartolomeo M, Bajetta E, Buzzoni R, Mariani L, Carnaghi C, Somma L, Zilembo N, di Leo A. Clinical efficacy of octreotide in the treatment of metastatic neuroendocrine tumors. A study by the Italian Trials in Medical Oncology Group. Cancer. 1996;77(2):402-8.
    • (1996) Cancer , vol.77 , Issue.2 , pp. 402-408
    • Di Bartolomeo, M.1    Bajetta, E.2    Buzzoni, R.3    Mariani, L.4    Carnaghi, C.5    Somma, L.6    Zilembo, N.7    Di Leo, A.8
  • 64
    • 3442884868 scopus 로고    scopus 로고
    • Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system
    • 1:STN:280:DC%2BD2c3lt12jug%3D%3D 15151956
    • Oberg K, Kvols L, Caplin M, Delle Fave G, de Herder W, Rindi G, Ruszniewski P, Woltering EA, Wiedenmann B. Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system. Ann Oncol. 2004;15(6):966-73.
    • (2004) Ann Oncol , vol.15 , Issue.6 , pp. 966-973
    • Oberg, K.1    Kvols, L.2    Caplin, M.3    Delle Fave, G.4    De Herder, W.5    Rindi, G.6    Ruszniewski, P.7    Woltering, E.A.8    Wiedenmann, B.9
  • 66
    • 79959373749 scopus 로고    scopus 로고
    • Long-term results of treatment of malignant carcinoid syndrome with prolonged release Lanreotide (Somatuline Autogel)
    • 1:CAS:528:DC%2BC3MXhtVajtb%2FE 21585408
    • Khan MS, El-Khouly F, Davies P, Toumpanakis C, Caplin ME. Long-term results of treatment of malignant carcinoid syndrome with prolonged release Lanreotide (Somatuline Autogel). Aliment Pharmacol Ther. 2011;34(2):235-42.
    • (2011) Aliment Pharmacol Ther , vol.34 , Issue.2 , pp. 235-242
    • Khan, M.S.1    El-Khouly, F.2    Davies, P.3    Toumpanakis, C.4    Caplin, M.E.5
  • 67
    • 84867411913 scopus 로고    scopus 로고
    • Pasireotide (SOM230) shows efficacy and tolerability in the treatment of patients with advanced neuroendocrine tumors refractory or resistant to octreotide LAR: Results from a phase II study
    • 1:CAS:528:DC%2BC38XhslGkt73M 22807497
    • Kvols LK, Oberg KE, O'Dorisio TM, Mohideen P, de Herder WW, Arnold R, Hu K, Zhang Y, Hughes G, Anthony L, Wiedenmann B. Pasireotide (SOM230) shows efficacy and tolerability in the treatment of patients with advanced neuroendocrine tumors refractory or resistant to octreotide LAR: results from a phase II study. Endocr Relat Cancer. 2012;19(5):657-66.
    • (2012) Endocr Relat Cancer , vol.19 , Issue.5 , pp. 657-666
    • Kvols, L.K.1    Oberg, K.E.2    O'Dorisio, T.M.3    Mohideen, P.4    De Herder, W.W.5    Arnold, R.6    Hu, K.7    Zhang, Y.8    Hughes, G.9    Anthony, L.10    Wiedenmann, B.11
  • 69
    • 84876134206 scopus 로고    scopus 로고
    • Neuroendocrine tumours of the small intestine
    • 1:CAS:528:DC%2BC3sXis1GksLw%3D 23582917
    • Strosberg J. Neuroendocrine tumours of the small intestine. Best Pract Res Clin Gastroenterol. 2012;26(6):755-73.
    • (2012) Best Pract Res Clin Gastroenterol , vol.26 , Issue.6 , pp. 755-773
    • Strosberg, J.1
  • 70
    • 0022408464 scopus 로고
    • Rapid reversal of carcinoid crisis with a somatostatin analogue
    • 1:STN:280:DyaL28%2FktVahtQ%3D%3D 2865675
    • Kvols LK, Martin JK, Marsh HM, Moertel CG. Rapid reversal of carcinoid crisis with a somatostatin analogue. N Engl J Med. 1985;313(19):1229-30.
    • (1985) N Engl J Med , vol.313 , Issue.19 , pp. 1229-1230
    • Kvols, L.K.1    Martin, J.K.2    Marsh, H.M.3    Moertel, C.G.4
  • 71
    • 84878275560 scopus 로고    scopus 로고
    • Octreotide LAR and bolus octreotide are insufficient for preventing intraoperative complications in carcinoid patients
    • 1:CAS:528:DC%2BC3sXosFejsrk%3D 23592524
    • Massimino K, Harrskog O, Pommier S, Pommier R. Octreotide LAR and bolus octreotide are insufficient for preventing intraoperative complications in carcinoid patients. J Surg Oncol. 2013;107(8):842-6.
    • (2013) J Surg Oncol , vol.107 , Issue.8 , pp. 842-846
    • Massimino, K.1    Harrskog, O.2    Pommier, S.3    Pommier, R.4
  • 74
    • 0030320681 scopus 로고    scopus 로고
    • Gastrointestinal endocrine tumours. Glucagonomas
    • 1:STN:280:DyaK2s3mvVShtg%3D%3D 9113318
    • Frankton S, Bloom SR. Gastrointestinal endocrine tumours. Glucagonomas. Baillieres Clin Gastroenterol. 1996;10(4):697-705.
    • (1996) Baillieres Clin Gastroenterol. , vol.10 , Issue.4 , pp. 697-705
    • Frankton, S.1    Bloom, S.R.2
  • 76
    • 33947582266 scopus 로고    scopus 로고
    • Medical treatment of benign insulinoma using octreotide LAR: A case report
    • 1:CAS:528:DC%2BD2sXlsVynt7k%3D 17124362
    • Usukura M, Yoneda T, Oda N, Yamamoto Y, Takata H, Hasatani K, Takeda Y. Medical treatment of benign insulinoma using octreotide LAR: a case report. Endocr J. 2007;54(1):95-101.
    • (2007) Endocr J , vol.54 , Issue.1 , pp. 95-101
    • Usukura, M.1    Yoneda, T.2    Oda, N.3    Yamamoto, Y.4    Takata, H.5    Hasatani, K.6    Takeda, Y.7
  • 77
    • 34447094133 scopus 로고    scopus 로고
    • Severe hypoglycaemia after long-acting octreotide in a patient with an unrecognized malignant insulinoma
    • 1:STN:280:DC%2BD2szitleksA%3D%3D 17535385
    • Healy ML, Dawson SJ, Murray RM, Zalcberg J, Jefford M. Severe hypoglycaemia after long-acting octreotide in a patient with an unrecognized malignant insulinoma. Intern Med J. 2007;37(6):406-9.
    • (2007) Intern Med J. , vol.37 , Issue.6 , pp. 406-409
    • Healy, M.L.1    Dawson, S.J.2    Murray, R.M.3    Zalcberg, J.4    Jefford, M.5
  • 79
    • 67249111683 scopus 로고    scopus 로고
    • Surgical management and palliative treatment in bronchial neuroendocrine tumours: A clinical study of 45 patients
    • 1:STN:280:DC%2BD1Mzotl2msw%3D%3D 19070398
    • Srirajaskanthan R, Toumpanakis C, Karpathakis A, Marelli L, Quigley AM, Dusmet M, Meyer T, Caplin ME. Surgical management and palliative treatment in bronchial neuroendocrine tumours: a clinical study of 45 patients. Lung Cancer. 2009;65(1):68-73.
    • (2009) Lung Cancer , vol.65 , Issue.1 , pp. 68-73
    • Srirajaskanthan, R.1    Toumpanakis, C.2    Karpathakis, A.3    Marelli, L.4    Quigley, A.M.5    Dusmet, M.6    Meyer, T.7    Caplin, M.E.8
  • 80
    • 67049108491 scopus 로고    scopus 로고
    • Cyclic ectopic Cushing's syndrome and somatostatin analogue treatment
    • Falhammar H. Cyclic ectopic Cushing's syndrome and somatostatin analogue treatment. N Z Med J. 2009;122(1294):92-5.
    • (2009) N Z Med J , vol.122 , Issue.1294 , pp. 92-95
    • Falhammar, H.1
  • 81
    • 80755155450 scopus 로고    scopus 로고
    • Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and the associated lung neuroendocrine tumors: Clinical experience with a rare entity
    • 21751183
    • Gorshtein A, Gross DJ, Barak D, Strenov Y, Refaeli Y, Shimon I, Grozinsky-Glasberg S. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and the associated lung neuroendocrine tumors: clinical experience with a rare entity. Cancer. 2012;118(3):612-9.
    • (2012) Cancer , vol.118 , Issue.3 , pp. 612-619
    • Gorshtein, A.1    Gross, D.J.2    Barak, D.3    Strenov, Y.4    Refaeli, Y.5    Shimon, I.6    Grozinsky-Glasberg, S.7
  • 82
    • 0027198659 scopus 로고
    • Octreotide as an antineoplastic agent in the treatment of functional and nonfunctional neuroendocrine tumors
    • 1:STN:280:DyaK3s3osVGrsA%3D%3D 8389666
    • Saltz L, Trochanowski B, Buckley M, Heffernan B, Niedzwiecki D, Tao Y, Kelsen D. Octreotide as an antineoplastic agent in the treatment of functional and nonfunctional neuroendocrine tumors. Cancer. 1993;72(1):244-8.
    • (1993) Cancer , vol.72 , Issue.1 , pp. 244-248
    • Saltz, L.1    Trochanowski, B.2    Buckley, M.3    Heffernan, B.4    Niedzwiecki, D.5    Tao, Y.6    Kelsen, D.7
  • 83
    • 0027296285 scopus 로고
    • Somatostatin analog sandostatin and inhibition of tumor growth in patients with metastatic endocrine gastroenteropancreatic tumors
    • 1:STN:280:DyaK3szmvF2rsQ%3D%3D 8395752
    • Arnold R, Neuhaus C, Benning R, Schwerk WB, Trautmann ME, Joseph K, Bruns C. Somatostatin analog sandostatin and inhibition of tumor growth in patients with metastatic endocrine gastroenteropancreatic tumors. World J Surg. 1993;17(4):511-9.
    • (1993) World J Surg , vol.17 , Issue.4 , pp. 511-519
    • Arnold, R.1    Neuhaus, C.2    Benning, R.3    Schwerk, W.B.4    Trautmann, M.E.5    Joseph, K.6    Bruns, C.7
  • 86
    • 0030667438 scopus 로고    scopus 로고
    • High-dose treatment with lanreotide of patients with advanced neuroendocrine gastrointestinal tumors: Clinical and biological effects
    • 1:STN:280:DyaK1c%2FmtlOksw%3D%3D 9402179
    • Eriksson B, Renstrup J, Imam H, Oberg K. High-dose treatment with lanreotide of patients with advanced neuroendocrine gastrointestinal tumors: clinical and biological effects. Ann Oncol. 1997;8(10):1041-4.
    • (1997) Ann Oncol , vol.8 , Issue.10 , pp. 1041-1044
    • Eriksson, B.1    Renstrup, J.2    Imam, H.3    Oberg, K.4
  • 89
    • 84911806523 scopus 로고    scopus 로고
    • Therapeutic biomarkers in lung neuroendocrine neoplasia
    • 1:CAS:528:DC%2BC2cXhs1KgtL7E 25252622
    • Righi L, Volante M, Rapa I, Vatrano S, Pelosi G, Papotti M. Therapeutic biomarkers in lung neuroendocrine neoplasia. Endocr Pathol. 2014;25(4):371-7.
    • (2014) Endocr Pathol. , vol.25 , Issue.4 , pp. 371-377
    • Righi, L.1    Volante, M.2    Rapa, I.3    Vatrano, S.4    Pelosi, G.5    Papotti, M.6
  • 90
    • 76049098419 scopus 로고    scopus 로고
    • Somatostatin receptor tissue distribution in lung neuroendocrine tumours: A clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases
    • 1:STN:280:DC%2BC3c7isVGnsg%3D%3D 19759190
    • Righi L, Volante M, Tavaglione V, Billè A, Daniele L, Angusti T, Inzani F, Pelosi G, Rindi G, Papotti M. Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases. Ann Oncol. 2010;21(3):548-55.
    • (2010) Ann Oncol , vol.21 , Issue.3 , pp. 548-555
    • Righi, L.1    Volante, M.2    Tavaglione, V.3    Billè, A.4    Daniele, L.5    Angusti, T.6    Inzani, F.7    Pelosi, G.8    Rindi, G.9    Papotti, M.10
  • 91
    • 83255167036 scopus 로고    scopus 로고
    • Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): A randomised, placebo-controlled, phase 3 study
    • 1:CAS:528:DC%2BC3MXhsF2rt7rM 22119496
    • Pavel ME, Hainsworth JD, Baudin E, et al. Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study. Lancet. 2011;378(9808):2005-12.
    • (2011) Lancet , vol.378 , Issue.9808 , pp. 2005-2012
    • Pavel, M.E.1    Hainsworth, J.D.2    Baudin, E.3
  • 92
    • 84875989281 scopus 로고    scopus 로고
    • Everolimus plus octreotide long-acting repeatable in patients with advanced lung neuroendocrine tumors: Analysis of the phase 3, randomized, placebo-controlled RADIANT-2 study
    • 1:CAS:528:DC%2BC3sXmslWmt7g%3D 23187897
    • Fazio N, Granberg D, Grossman A, Saletan S, Klimovsky J, Panneerselvam A, Wolin EM. Everolimus plus octreotide long-acting repeatable in patients with advanced lung neuroendocrine tumors: analysis of the phase 3, randomized, placebo-controlled RADIANT-2 study. Chest. 2013;143(4):955-62.
    • (2013) Chest , vol.143 , Issue.4 , pp. 955-962
    • Fazio, N.1    Granberg, D.2    Grossman, A.3    Saletan, S.4    Klimovsky, J.5    Panneerselvam, A.6    Wolin, E.M.7
  • 95
    • 84906976762 scopus 로고    scopus 로고
    • Clinical benefits of above-standard dose of octreotide LAR in patients with neuroendocrine tumors for control of carcinoid syndrome symptoms: A multicenter retrospective chart review study
    • 25096997
    • Strosberg JR, Benson AB, Huynh L, Duh MS, Goldman J, Sahai V, Rademaker AW, Kulke MH. Clinical benefits of above-standard dose of octreotide LAR in patients with neuroendocrine tumors for control of carcinoid syndrome symptoms: a multicenter retrospective chart review study. Oncologist. 2014;19(9):930-6.
    • (2014) Oncologist. , vol.19 , Issue.9 , pp. 930-936
    • Strosberg, J.R.1    Benson, A.B.2    Huynh, L.3    Duh, M.S.4    Goldman, J.5    Sahai, V.6    Rademaker, A.W.7    Kulke, M.H.8
  • 96
    • 0344132653 scopus 로고    scopus 로고
    • Ultra-high-dose lanreotide treatment in patients with metastatic neuroendocrine gastroenteropancreatic tumors
    • 1:CAS:528:DyaK1MXls1Klsrw%3D 10473972
    • Faiss S, Räth U, Mansmann U, Caird D, Clemens N, Riecken EO, Wiedenmann B. Ultra-high-dose lanreotide treatment in patients with metastatic neuroendocrine gastroenteropancreatic tumors. Digestion. 1999;60(5):469-76.
    • (1999) Digestion. , vol.60 , Issue.5 , pp. 469-476
    • Faiss, S.1    Räth, U.2    Mansmann, U.3    Caird, D.4    Clemens, N.5    Riecken, E.O.6    Wiedenmann, B.7
  • 98
    • 79960247571 scopus 로고    scopus 로고
    • Effects of Sandostatin LAR on gastrointestinal motility in patients with neuroendocrine tumors
    • 1:CAS:528:DC%2BC3MXoslOht78%3D 21623673
    • Gregersen T, Grønbæk H, Worsøe J, Schlageter V, Laurberg S, Krogh K. Effects of Sandostatin LAR on gastrointestinal motility in patients with neuroendocrine tumors. Scand J Gastroenterol. 2011;46(7-8):895-902.
    • (2011) Scand J Gastroenterol , vol.46 , Issue.7-8 , pp. 895-902
    • Gregersen, T.1    Grønbæk, H.2    Worsøe, J.3    Schlageter, V.4    Laurberg, S.5    Krogh, K.6
  • 100
    • 84856094615 scopus 로고    scopus 로고
    • DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours
    • 22065857
    • Plöckinger U, Hoffmann U, Geese M, Lupp A, Buchfelder M, Flitsch J, Vajkoczy P, Jakob W, Saeger W, Schulz S, Dohrmann C. DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours. Eur J Endocrinol. 2012;166(2):223-34.
    • (2012) Eur J Endocrinol , vol.166 , Issue.2 , pp. 223-234
    • Plöckinger, U.1    Hoffmann, U.2    Geese, M.3    Lupp, A.4    Buchfelder, M.5    Flitsch, J.6    Vajkoczy, P.7    Jakob, W.8    Saeger, W.9    Schulz, S.10    Dohrmann, C.11
  • 101
    • 84886415154 scopus 로고    scopus 로고
    • The novel somatostatin receptor 2/dopamine type 2 receptor chimeric compound BIM-23A758 decreases the viability of human GOT1 midgut carcinoid cells
    • 1:CAS:528:DC%2BC3sXhs1ehtrzL 23797089
    • Zitzmann K, Andersen S, Vlotides G, Spöttl G, Zhang S, Datta R, Culler M, Göke B, Auernhammer CJ. The novel somatostatin receptor 2/dopamine type 2 receptor chimeric compound BIM-23A758 decreases the viability of human GOT1 midgut carcinoid cells. Neuroendocrinology. 2013;98(2):128-36.
    • (2013) Neuroendocrinology , vol.98 , Issue.2 , pp. 128-136
    • Zitzmann, K.1    Andersen, S.2    Vlotides, G.3    Spöttl, G.4    Zhang, S.5    Datta, R.6    Culler, M.7    Göke, B.8    Auernhammer, C.J.9
  • 102
    • 84886903634 scopus 로고    scopus 로고
    • Targeting the somatostatin receptor in pituitary and neuroendocrine tumors
    • 1:CAS:528:DC%2BC3sXhvVehsLrF 23991721
    • Veenstra MJ, de Herder WW, Feelders RA, Hofland LJ. Targeting the somatostatin receptor in pituitary and neuroendocrine tumors. Expert Opin Ther Targets. 2013;17(11):1329-43.
    • (2013) Expert Opin Ther Targets. , vol.17 , Issue.11 , pp. 1329-1343
    • Veenstra, M.J.1    De Herder, W.W.2    Feelders, R.A.3    Hofland, L.J.4
  • 103
    • 84873453446 scopus 로고    scopus 로고
    • The expanding role of somatostatin analogs in the management of neuroendocrine tumors
    • 23112884
    • Wolin EM. The expanding role of somatostatin analogs in the management of neuroendocrine tumors. Gastrointest Cancer Res. 2012;5(5):161-8.
    • (2012) Gastrointest Cancer Res. , vol.5 , Issue.5 , pp. 161-168
    • Wolin, E.M.1
  • 104
    • 84862091799 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of a single dose of pasireotide long-acting release in healthy volunteers: A single-center Phase i study
    • 1:CAS:528:DC%2BC38XnvFKksrk%3D 22383336
    • Dietrich H, Hu K, Ruffin M, Song D, Bouillaud E, Wang Y, Hasskarl J. Safety, tolerability, and pharmacokinetics of a single dose of pasireotide long-acting release in healthy volunteers: a single-center Phase I study. Eur J Endocrinol. 2012;166(5):821-8.
    • (2012) Eur J Endocrinol , vol.166 , Issue.5 , pp. 821-828
    • Dietrich, H.1    Hu, K.2    Ruffin, M.3    Song, D.4    Bouillaud, E.5    Wang, Y.6    Hasskarl, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.