MicroRNA-765 influences arterial stiffness through modulating apelin expression

Molecular and Cellular Endocrinology

Volumn 411, Issue , 2015, Pages 11-19

  Liao, Yi Chu ^a,b   Wang, Yung Song ^c   Hsi, Edward ^d,e   Chang, Ming Hung ^f   You, Yun Zhen ^f   Juo, Suh Hang Hank ^d,e  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Arterial stiffness; Endothelial nitric oxide synthase; MicroRNAs; Single nucleotide polymorphism

Indexed keywords

ADENYLATE KINASE; APELIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE A; GELATINASE B; MESSENGER RNA; MICRORNA; MICRORNA 765; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; APLN PROTEIN, HUMAN; MIRN765 MICRORNA, HUMAN; NOS3 PROTEIN, HUMAN; SIGNAL PEPTIDE;

3' UNTRANSLATED REGION; ADULT; APELIN GENE; ARTERIAL STIFFNESS; ARTICLE; BINDING SITE; BIOASSAY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE FUNCTION; GENE INDUCTION; GENE LOCATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC SCREENING; HUMAN; INTRACELLULAR SIGNALING; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS; ALLELE; GENETICS; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

3' UNTRANSLATED REGIONS; ADULT; ALLELES; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICRORNAS; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-AKT; SEX FACTORS; SIGNAL TRANSDUCTION; VASCULAR STIFFNESS;

EID: 84930181093     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.04.006     Document Type: Article

References (35)

1. Anea C.B., Ali M.I., Osmond J.M., Sullivan J.C., Stepp D.W., Merloiu A.M., et al. Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice. Arterioscler. Thromb. Vasc. Biol 2010, 30(12):2535-2543.
2. Ba H.J., Chen H.S., Su Z., Du M.L., Chen Q.L., Li Y.H., et al. Associations between serum apelin-12 levels and obesity-related markers in Chinese children. PLoS ONE 2014, 9(1):e86577.
3. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21(2):263-265.
4. Brillante D.G., O'Sullivan A.J., Howes L.G. Arterial stiffness in insulin resistance: the role of nitric oxide and angiotensin II receptors. Vasc. Health Risk Manag 2009, 5(1):73-78.
5. Chun H.J., Ali Z.A., Kojima Y., Kundu R.K., Sheikh A.Y., Agrawal R., et al. Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J. Clin. Invest 2008, 118(10):3343-3354.
6. Deryugina E.I., Quigley J.P. Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions. Biochim. Biophys. Acta 2010, 1803(1):103-120.
7. Enright A.J., John B., Gaul U., Tuschl T., Sander C., Marks D.S. MicroRNA targets in drosophila. Genome Biol 2003, 5(1):R1.
8. Godin D., Ivan E., Johnson C., Magid R., Galis Z.S. Remodeling of carotid artery is associated with increased expression of matrix metalloproteinases in mouse blood flow cessation model. Circulation 2000, 102(23):2861-2866.
9. Harada A., Okada T., Niki K., Chang D., Sugawara M. On-line noninvasive one-point measurements of pulse wave velocity. Heart Vessels 2002, 17(2):61-68.
10. Ho J.J., Robb G.B., Tai S.C., Turgeon P.J., Mawji I.A., Man H.S., et al. Active stabilization of human endothelial nitric oxide synthase mRNA by hnRNP E1 protects against antisense RNA and microRNAs. Mol. Cell. Biol 2013, 33(10):2029-2046.
11. Huntzinger E., Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat. Rev. Genet 2011, 12(2):99-110.
12. Japp A.G., Cruden N.L., Amer D.A., Li V.K., Goudie E.B., Johnston N.R., et al. Vascular effects of apelin in vivo in man. J. Am. Coll. Cardiol 2008, 52(11):908-913.
13. Jin W., Su X., Xu M., Liu Y., Shi J., Lu L., et al. Interactive association of five candidate polymorphisms in Apelin/APJ pathway with coronary artery disease among Chinese hypertensive patients. PLoS ONE 2012, 7(12):e51123.
14. Juo S.H., Wyszynski D.F., Beaty T.H., Huang H.Y., Bailey-Wilson J.E. Mild association between the A/G polymorphism in the promoter of the apolipoprotein A-I gene and apolipoprotein A-I levels: a meta-analysis. Am. J. Med. Genet 1999, 82(3):235-241.
15. Kruger J., Rehmsmeier M. RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Res 2006, 34:W451-W454.
16. Kupai K., Szucs G., Cseh S., Hajdu I., Csonka C., Csont T., et al. Matrix metalloproteinase activity assays: importance of zymography. J. Pharmacol. Toxicol. Methods 2010, 61(2):205-209.
17. Lacolley P., Challande P., Osborne-Pellegrin M., Regnault V. Genetics and pathophysiology of arterial stiffness. Cardiovasc. Res 2009, 81(4):637-648.
18. Li Z., Bai Y., Hu J. Reduced apelin levels in stable angina. Intern. Med 2008, 47(22):1951-1955.
19. Liao Y.C., Chou W.W., Li Y.N., Chuang S.C., Lin W.Y., Lakkakula B.V., et al. Apelin gene polymorphism influences apelin expression and obesity phenotypes in Chinese women. Am. J. Clin. Nutr 2011, 94(3):921-928.
20. Liao Y.C., Wang Y.S., Guo Y.C., Lin W.L., Chang M.H., Juo S.H. Let-7g improves multiple endothelial functions through targeting transforming growth factor-beta and SIRT-1 signaling. J. Am. Coll. Cardiol 2014, 63(16):1685-1694.
21. Lin H.F., Liu C.K., Liao Y.C., Lin R.T., Chen C.S., Juo S.H. The risk of the metabolic syndrome on carotid thickness and stiffness: sex and age specific effects. Atherosclerosis 2010, 210(1):155-159.
22. Liu M.E., Liao Y.C., Lin R.T., Wang Y.S., Hsi E., Lin H.F., et al. A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosis. Atherosclerosis 2013, 228(1):161-167.
23. Masri B., Morin N., Cornu M., Knibiehler B., Audigier Y. Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells. FASEB J. 2004, 18(15):1909-1911.
24. Mount P.F., Kemp B.E., Power D.A. Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J. Mol. Cell. Cardiol 2007, 42(2):271-279.
25. Nazari-Jahantigh M., Wei Y., Schober A. The role of microRNAs in arterial remodelling. Thromb. Haemost 2012, 107(4):611-618.
26. Quazi R., Palaniswamy C., Frishman W.H. The emerging role of apelin in cardiovascular disease and health. Cardiol. Rev 2009, 17(6):283-286.
27. Shan P.F., Lu Y., Cui R.R., Jiang Y., Yuan L.Q., Liao E.Y. Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells. PLoS ONE 2011, 6(3):e17938.
28. Stehouwer C.D., Henry R.M., Ferreira I. Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease. Diabetologia 2008, 51(4):527-539.
29. Sugawara J., Komine H., Hayashi K., Yoshizawa M., Yokoi T., Otsuki T., et al. Effect of systemic nitric oxide synthase inhibition on arterial stiffness in humans. Hypertens. Res 2007, 30(5):411-415.
30. Tsai E.M., Wang Y.S., Lin C.S., Lin W.Y., Hsi E., Wu M.T., et al. A microRNA-520 mir SNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women. J. Hum. Genet 2013, 58(4):202-209.
31. Vlachopoulos C., Aznaouridis K., Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J. Am. Coll. Cardiol 2010, 55(13):1318-1327.
32. Westerbacka J., Yki-Jarvinen H. Arterial stiffness and insulin resistance. Semin. Vasc. Med 2002, 2(2):157-164.
33. Yasmin, McEniery C.M., Wallace S., Dakham Z., Pulsalkar P., Maki-Petaja K., et al. Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness. Arterioscler. Thromb. Vasc. Biol 2005, 25(2):372.
34. Yu X.H., Tang Z.B., Liu L.J., Qian H., Tang S.L., Zhang D.W., et al. Apelin and its receptor APJ in cardiovascular diseases. Clin. Chim. Acta 2014, 428:1-8.
35. Zieman S.J., Melenovsky V., Kass D.A. Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler. Thromb. Vasc. Biol 2005, 25(5):932-943.