A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women

Journal of Human Genetics

Volumn 58, Issue 4, 2013, Pages 202-209

  Tsai, Eing Mei ^a,b   Wang, Yung Song ^b   Lin, Chang Shen ^b   Lin, Wen Yin ^b   Hsi, Edward ^b   Wu, Ming Tsang ^a,b   Juo, Suh Hang H ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Endometriosis; microRNA 520; MMP2; Polymorphism

Indexed keywords

GELATINASE A; MICRORNA; MICRORNA 520G; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BINDING AFFINITY; BINDING SITE; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; ENDOMETRIOSIS; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE SILENCING; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PREDICTIVE VALUE; REGRESSION ANALYSIS; REPORTER GENE; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; ENDOMETRIOSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MATRIX METALLOPROTEINASE 2; MICRORNAS; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS;

EID: 84877050069     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2013.1     Document Type: Article

References (34)

1. Hadfield, R. M., Mardon, H. J., Barlow, D. H. & Kennedy, S. H. Endometriosis in monozygotic twins. Fertil. Steril. 68, 941-942 (1997
2. Simpson, J. L. & Bischoff, F. Z. Heritability and molecular genetic studies of endometriosis. Ann. NY Acad. Sci. 955, 239-251 (2002
3. Tempfer, C. B., Simoni, M., Destenaves, B. & Fauser, B. C. Functional genetic polymorphisms and female reproductive disorders: Part II - endometriosis. Hum. Reprod. Update 15, 97-118 (2009
4. Giudice, L. C. & Kao, L. C. Endometriosis. Lancet 364, 1789-1799 (2004
5. Curry, Jr T. E. & Osteen, K. G. The matrix metalloproteinase system: Changes, regulation, and impact throughout the ovarian and uterine reproductive cycle. Endocr. Rev. 24, 428-465 (2003
6. Chung, H. W., Lee, J. Y., Moon, H. S., Hur, S. E., Park, M. H., Wen, Y. et al. Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium. Fertil. Steril. 78, 787-795 (2002
7. Rawdanowicz, T. J., Hampton, A. L., Nagase, H., Woolley, D. E. & Salamonsen, L. A. Matrix metalloproteinase production by cultured human endometrial stromal cells: Identification of interstitial collagenase, gelatinase-A, gelatinase-B, and stromelysin-1 and their differential regulation by interleukin-1 alpha and tumor necrosis factor-alpha. J. Clin. Endocrinol. Metab. 79, 530-536 (1994
8. Huang, H. F., Hong, L. H., Tan, Y. & Sheng, J. Z. Matrix metalloproteinase 2 is associated with changes in steroid hormones in the sera and peritoneal fluid of patients with endometriosis. Fertil. Steril. 81, 1235-1239 (2004
9. Inagaki, N., Ung, L., Otani, T., Wilkinson, D. & Lopata, A. Uterine cavity matrix metalloproteinases and cytokines in patients with leiomyoma, adenomyosis or endometrial polyp. Eur. J. Obstet. Gynecol. Reprod. Biol. 111, 197-203 (2003
10. Uzan, C., Cortez, A., Dufournet, C., Fauvet, R., Siffroi, J. P. & Darai, E. Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissues express a different profile of matrix metalloproteinases-2, -3 and -11, and of tissue inhibitor metalloproteinases-1 and -2. Virchows Arch. 445, 603-609 (2004
11. Juo, S. H., Wang, T. N., Lee, J. N., Wu, M. T., Long, C. Y. & Tsai, E. M. CYP17, CYP1A1 and COMT polymorphisms and the risk of adenomyosis and endometriosis in Taiwanese women. Hum. Reprod. 21, 1498-1502 (2006
12. Tsai, H. T., Wu, C. H., Lai, H. L., Li, R. N., Tung, Y. C., Chuang, H. Y. et al. Association between quantitative high-risk human papillomavirus DNA load and cervical intraepithelial neoplasm risk. Cancer Epidemiol. Biomarkers Prev. 14, 1-6 (2005
13. Wu, M. T., Lee, L. H., Ho, C. K., Liu, C. L., Wu, T. N., Wu, S. C. et al. Lifetime exposure to environmental tobacco smoke and cervical intraepithelial neoplasms among nonsmoking Taiwanese women. Arch. Environ. Health 58, 353-359 (2003
14. Juo, S. H., Wu, R., Lin, C. S., Wu, M. T., Lee, J. N. & Tsai, E. M. A functional promoter polymorphism in interleukin-10 gene influences susceptibility to endometriosis. Fertil. Steril. 92, 1228-1233 (2009
15. Price, S. J., Greaves, D. R. & Watkins, H. Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: Role of Sp1 in allele-specific transcriptional regulation. J. Biol. Chem. 276, 7549-7558 (2001
16. Wang, L. F., Chien, C. Y., Kuo, W. R., Tai, C. F. & Juo, S. H. Matrix metalloproteinase-2 gene polymorphisms in nasal polyps. Arch. Otolaryngol. Head Neck Surg. 134, 852-856 (2008
17. Tzeng, J. Y., Wang, C. H., Kao, J. T. & Hsiao, C. K. Regression-based association analysis with clustered haplotypes through use of genotypes. Am. J. Hum. Genet. 78, 231-242 (2006)
18. Ueda, M., Yamashita, Y., Takehara, M., Terai, Y., Kumagai, K., Ueki, K. et al. Gene expression of adhesion molecules and matrix metalloproteinases in endometriosis. Gynecol. Endocrinol. 16, 391-402 (2002
19. Lin, S. C., Lo, S. S., Liu, C. J., Chung, M. Y., Huang, J. W. & Chang, K. W. Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis. J. Oral Pathol. Med. 33, 405-409 (2004
20. Ye, S. Influence of matrix metalloproteinase genotype on cardiovascular disease susceptibility and outcome. Cardiovasc. Res. 69, 636-645 (2006
21. Saare, M., Lamp, M., Kaart, T., Karro, H., Kadastik, U., Metspalu, A. et al. Polymorphisms in MMP-2 and MMP-9 promoter regions are associated with endometriosis. Fertil. Steril. 94, 1560-1563 (2010
22. Kang, S., Zhao, X. W., Wang, N., Chen, S. C., Zhou, R. M. & Li, Y. Association of polymorphisms of the MMP-2 and TIMP-2 genes with the risk of endometriosis in North Chinese women. Fertil. Steril. 90, 2023-2029 (2008
23. Zhao, X. W., Li, Y., Wang, N., Zhao, J., Li, X. L., Liu, Q. et al. Study on the association of SNPs of MMP-2 and TIMP-2 genes with the risk of endometriosis and adenomyosis. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25, 280-283 (2008
24. Fatar, M., Stroick, M., Steffens, M., Senn, E., Reuter, B., Bukow, S. et al. Singlenucleotide polymorphisms of MMP-2 gene in stroke subtypes. Cerebrovasc. Dis. 26, 113-119 (2008
25. Pan, Q., Luo, X., Toloubeydokhti, T. & Chegini, N. The expression profile of micro-RNA in endometrium and endometriosis and the influence of ovarian steroids on their expression. Mol. Hum. Reprod. 13, 797-806 (2007
26. Ohlsson Teague, E. M., Van der Hoek, K. H., Van der Hoek, M. B., Perry, N., Wagaarachchi, P., Robertson, S. A. et al. MicroRNA-regulated pathways associated with endometriosis. Mol. Endocrinol. 23, 265-275 (2009
27. Filigheddu, N., Gregnanin, I., Porporato, P. E., Surico, D., Perego, B., Galli, L. et al. Differential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis. J. Biomed. Biotechnol. 2010, 369549 (2010
28. Hawkins, S. M., Creighton, C. J., Han, D. Y., Zariff, A., Anderson, M. L., Gunaratne, P. H. et al. Functional microRNA involved in endometriosis. Mol. Endocrinol. 25, 821-832 (2011
29. Melichar, V. O., Behr-Roussel, D., Zabel, U., Uttenthal, L. O., Rodrigo, J., Rupin, A. et al. Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis. Proc. Natl Acad. Sci. USA 101, 16671-16676 (2004
30. Mishra, P. J., Humeniuk, R., Longo-Sorbello, G. S., Banerjee, D. & Bertino, J. R. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc. Natl Acad. Sci. USA 104, 13513-13518 (2007
31. Mishra, P. J., Banerjee, D. & Bertino, J. R. MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics. Cell Cycle 7, 853-858 (2008
32. Zhao, Z. Z., Croft, L., Nyholt, D. R., Chapman, B., Treloar, S. A., Hull, M. L. et al. Evaluation of polymorphisms in predicted target sites for micro RNAs differentially expressed in endometriosis. Mol. Hum. Reprod. 17, 92-103 (2011
33. Grechukhina, O., Petracco, R., Popkhadze, S., Massasa, E., Paranjape, T., Chan, E. et al. A polymorphism in a let-7 microRNA binding site of KRAS in women with endometriosis. EMBO Mol. Med. 4, 206-217 (2012
34. Yu, C., Pan, K., Xing, D., Liang, G., Tan, W., Zhang, L. et al. Correlation between a single nucleotide polymorphism in the matrix metalloproteinase-2 promoter and risk of lung cancer. Cancer Res. 62, 6430-6433 (2002