메뉴 건너뛰기




Volumn 88, Issue 2, 2015, Pages 167-179

Basal cell carcinoma: Pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management

Author keywords

Basal cell carcinoma; BCC; ED C; Electrodesiccation and curettage; Mohs surgery; Surgical excision

Indexed keywords

FLUOROURACIL; IMIQUIMOD; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2; ANTINEOPLASTIC AGENT;

EID: 84930164917     PISSN: 00440086     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (288)

References (102)
  • 1
    • 72849181879 scopus 로고
    • Multiple nevoid basal-cell epithe-lioma, jaw cysts and bifid rib. A syndrome
    • Gorlin RJ, Goltz RW. Multiple nevoid basal-cell epithe-lioma, jaw cysts and bifid rib. A syndrome. N Engl J Med. 1960;262:908-12.
    • (1960) N Engl J Med , vol.262 , pp. 908-912
    • Gorlin, R.J.1    Goltz, R.W.2
  • 2
    • 0026627965 scopus 로고
    • Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9
    • Gailani MR, Bale SJ, Leffell DJ, DiGiovanna JJ, Peck GL, Poliak S, et al. Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9. Cell. 1992;69(1):111-7.
    • (1992) Cell , vol.69 , Issue.1 , pp. 111-117
    • Gailani, M.R.1    Bale, S.J.2    Leffell, D.J.3    Digiovanna, J.J.4    Peck, G.L.5    Poliak, S.6
  • 3
    • 0026602737 scopus 로고
    • Kilpatrick Mw. Location of gene for Gorlin syndrome
    • Farndon PA, Del Mastro RG, Evans DG, Kilpatrick Mw. Location of gene for Gorlin syndrome. Lancet. 1992;339(8793):581-2.
    • (1992) Lancet , vol.339 , Issue.8793 , pp. 581-582
    • Farndon, P.A.1    Del Mastro, R.G.2    Evans, D.G.3
  • 4
    • 0026559322 scopus 로고
    • Localisation of gene for the naevoid basal-cell car
    • Reis A, Kuster W, Linss G, Gebel E, Hamm H, Fuhrmann W, et al. Localisation of gene for the naevoid basal-cell carcinoma syndrome. Lancet. 1992;339(8793):617.
    • (1992) Lancet , vol.339 , Issue.8793 , pp. 617
    • Reis, A.1    Kuster, W.2    Linss, G.3    Gebel, E.4    Hamm, H.5    Fuhrmann, W.6
  • 6
    • 15844386165 scopus 로고    scopus 로고
    • Mutations of the human ho-molog of Drosophila patched in the nevoid basal cell carcinoma syndrome
    • Hahn H, wicking C, Zaphiropoulous PG, Gailani MR, Shan-ley S, Chidambaram A, et al. Mutations of the human ho-molog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell. 1996;85(6):841-51.
    • (1996) Cell , vol.85 , Issue.6 , pp. 841-851
    • Hahn, H.1    Wicking, C.2    Zaphiropoulous, P.G.3    Gailani, M.R.4    Shan-Ley, S.5    Chidambaram, A.6
  • 7
    • 15844381336 scopus 로고    scopus 로고
    • Human homolog of patched, a candidate gene for the basal cell nevus syndrome
    • Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science. 1996;272(5268):1668-71.
    • (1996) Science , vol.272 , Issue.5268 , pp. 1668-1671
    • Johnson, R.L.1    Rothman, A.L.2    Xie, J.3    Goodrich, L.V.4    Bare, J.W.5    Bonifas, J.M.6
  • 8
    • 0011102935 scopus 로고    scopus 로고
    • The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
    • Stone DM, Hynes M, Armanini M, Swanson TA, Gu Q, Johnson RL, et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature. 1996;384(6605):129-34.
    • (1996) Nature , vol.384 , Issue.6605 , pp. 129-134
    • Stone, D.M.1    Hynes, M.2    Armanini, M.3    Swanson, T.A.4    Gu, Q.5    Johnson, R.L.6
  • 9
    • 0030802458 scopus 로고    scopus 로고
    • Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog
    • Fan H, Oro AE, Scott MP, Khavari PA. induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat Med. 1997;3(7):788-92.
    • (1997) Nat Med , vol.3 , Issue.7 , pp. 788-792
    • Fan, H.1    Oro, A.E.2    Scott, M.P.3    Khavari, P.A.4
  • 11
    • 0031913524 scopus 로고    scopus 로고
    • Activating Smoothened mutations in sporadic basal-cell carcinoma
    • Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, et al. Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature. 1998;391(6662):90-2.
    • (1998) Nature , vol.391 , Issue.6662 , pp. 90-92
    • Xie, J.1    Murone, M.2    Luoh, S.M.3    Ryan, A.4    Gu, Q.5    Zhang, C.6
  • 12
    • 0034091805 scopus 로고    scopus 로고
    • Basal cell carcinomas in mice overexpressing Gli2 in skin
    • Grachtchouk M, Mo R, Yu S, Zhang X, Sasaki H, Hui CC, et al. Basal cell carcinomas in mice overexpressing Gli2 in skin. Nat Genet. 2000;24(3):216-7.
    • (2000) Nat Genet , vol.24 , Issue.3 , pp. 216-217
    • Grachtchouk, M.1    Mo, R.2    Yu, S.3    Zhang, X.4    Sasaki, H.5    Hui, C.C.6
  • 13
    • 0034724219 scopus 로고    scopus 로고
    • Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLi-1
    • Nilsson M, Unden AB, Krause D, Malmqwist U, Raza K, Zaphiropoulos PG, et al. induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLi-1. Proc Natl Acad Sci USA. 2000;97(7):3438-43.
    • (2000) Proc , vol.97 , Issue.7 , pp. 3438-3443
    • Nilsson, M.1    Unden, A.B.2    Krause, D.3    Malmqwist, U.4    Raza, K.5    Zaphiropoulos, P.G.6
  • 14
    • 19944429892 scopus 로고    scopus 로고
    • Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: Conditional skin tumorigenesis recapitulates the hair growth cycle
    • Hutchin ME, Kariapper MS, Grachtchouk M, wang A, wei L, Cummings D, et al. Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev. 2005;19(2):214-23.
    • (2005) Genes Dev , vol.19 , Issue.2 , pp. 214-223
    • Hutchin, M.E.1    Kariapper, M.S.2    Grachtchouk, M.3    Wang, A.4    Wei, L.5    Cummings, D.6
  • 15
    • 84930149752 scopus 로고    scopus 로고
    • Principles of Tumor Biology and Pathogenesis of BCCs and SCCs
    • in: Bolognia JL, Jorizzo JL, Schaffer J v, editors, 3rd edition. Saunders
    • O’Toole EA, Ponten F, Lundeberg J, Asplund A. Principles of Tumor Biology and Pathogenesis of BCCs and SCCs. in: Bolognia JL, Jorizzo JL, Schaffer J v, editors. Dermatology. 3rd edition. Saunders; 2012. p. 1759-72.
    • (2012) Dermatology , pp. 1759-1772
    • O’Toole, E.A.1    Ponten, F.2    Lundeberg, J.3    Asplund, A.4
  • 16
    • 0030881082 scopus 로고    scopus 로고
    • Molecular pathology in basal cell cancer with p53 as a genetic marker
    • Ponten F, Berg C, Ahmadian A, Ren ZP, Nister M, Lunde-berg J, et al. Molecular pathology in basal cell cancer with p53 as a genetic marker. Oncogene. 1997;15(9):1059-67.
    • (1997) Oncogene , vol.15 , Issue.9 , pp. 1059-1067
    • Ponten, F.1    Berg, C.2    Ahmadian, A.3    Ren, Z.P.4    Nister, M.5    Lunde-Berg, J.6
  • 18
    • 79955508675 scopus 로고    scopus 로고
    • Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations
    • Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, wang A, et al. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations. J Clin invest. 2011;121(5):1768-81.
    • (2011) J Clin Invest , vol.121 , Issue.5 , pp. 1768-1781
    • Grachtchouk, M.1    Pero, J.2    Yang, S.H.3    Ermilov, A.N.4    Michael, L.E.5    Wang, A.6
  • 19
    • 78651467232 scopus 로고    scopus 로고
    • Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice
    • wang GY, wang J, Mancianti ML, Epstein EH Jr. Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice. Cancer Cell. 2011;19(1):114-24.
    • (2011) Cancer Cell , vol.19 , Issue.1 , pp. 114-124
    • Wang, G.Y.1    Wang, J.2    Mancianti, M.L.3    Epstein, E.H.4
  • 20
    • 78651428420 scopus 로고    scopus 로고
    • Keratin 15-positive stem cells give rise to basal cell carcinomas in irradiated Ptch1(+/-) mice
    • Seykora JT, Cotsarelis G. Keratin 15-positive stem cells give rise to basal cell carcinomas in irradiated Ptch1(+/-) mice. Cancer Cell. 2011;19(1):5-6.
    • (2011) Cancer Cell , vol.19 , Issue.1 , pp. 5-6
    • Seykora, J.T.1    Cotsarelis, G.2
  • 21
    • 0003432464 scopus 로고    scopus 로고
    • Cancer Facts & Figures, in, ternet]. Available from:
    • Cancer Facts & Figures 2010. American Cancer Society [internet]. Available from: http://www.cancer.org/research/can-cerfactsstatistics/cancerfactsfigures2010/index.
    • (2010) American Cancer Society
  • 23
    • 0029731733 scopus 로고    scopus 로고
    • Lifetime risk for development of skin cancer in the U.S. population: Current estimate is now 1 in 5
    • Rigel DS, Friedman RJ, Kopf AW. Lifetime risk for development of skin cancer in the U.S. population: current estimate is now 1 in 5. J Am Acad Dermatol. 1996;35(6):1012-3.
    • (1996) J am Acad Dermatol , vol.35 , Issue.6 , pp. 1012-1013
    • Rigel, D.S.1    Friedman, R.J.2    Kopf, A.W.3
  • 25
    • 0027249629 scopus 로고
    • Basal cell carcinoma in Kauai, Hawaii: The highest documented incidence in the United States
    • Reizner GT, Chuang TY, Elpern DJ, Stone JL, Farmer ER. Basal cell carcinoma in Kauai, Hawaii: the highest documented incidence in the United States. J Am Acad Dermatol. 1993;29(2 Pt 1):184-9.
    • (1993) J am Acad Dermatol , vol.29 , Issue.2 , pp. 184-189
    • Reizner, G.T.1    Chuang, T.Y.2    Elpern, D.J.3    Stone, J.L.4    Farmer, E.R.5
  • 27
    • 0025602283 scopus 로고
    • The risk of developing subsequent nonmelanoma skin cancers
    • Schreiber MM, Moon TE, Fox SH, Davidson J. The risk of developing subsequent nonmelanoma skin cancers. J Am Acad Dermatol. 1990;23(6 Pt 1):1114-8.
    • (1990) J am Acad Dermatol , vol.23 , Issue.6 , pp. 1114-1118
    • Schreiber, M.M.1    Moon, T.E.2    Fox, S.H.3    Davidson, J.4
  • 28
    • 0026625172 scopus 로고
    • Risk of subsequent basal cell carcinoma and squa-
    • Karagas MR, Stukel TA, Greenberg ER, Baron JA, Mott LA, Stern RS. Risk of subsequent basal cell carcinoma and squa-mous cell carcinoma of the skin among patients with prior skin cancer. Skin Cancer Prevention Study Group. JAMA. 1992;267(24):3305-10.
    • (1992) JAMA , vol.267 , Issue.24 , pp. 3305-3310
    • Karagas, M.R.1    Stukel, T.A.2    Greenberg, E.R.3    Baron, J.A.4    Mott, L.A.5    Stern, R.S.6
  • 29
  • 30
    • 0034536150 scopus 로고    scopus 로고
    • Risk of developing a subsequent non-melanoma skin cancer in patients with a history of non-melanoma skin cancer: A critical review of the literature and meta-analysis
    • Marcil I, Stern RS. Risk of developing a subsequent non-melanoma skin cancer in patients with a history of non-melanoma skin cancer: a critical review of the literature and meta-analysis. Arch Dermatol. 2000;136(12):1524-30.
    • (2000) Arch Dermatol , vol.136 , Issue.12 , pp. 1524-1530
    • Marcil, I.1    Stern, R.S.2
  • 31
    • 0035098959 scopus 로고    scopus 로고
    • Risk of synchronous and metachronous second nonmelanoma skin cancer when referred for Mohs micrographic surgery
    • Schinstine M, Goldman GD. Risk of synchronous and metachronous second nonmelanoma skin cancer when referred for Mohs micrographic surgery. J Am Acad Derma-tol. 2001;44(3):497-9.
    • (2001) J am Acad Derma-Tol , vol.44 , Issue.3 , pp. 497-499
    • Schinstine, M.1    Goldman, G.D.2
  • 32
    • 0028580578 scopus 로고
    • Basal cell and squamous cell carcinomas are im
    • Marghoob AA, Slade J, Salopek TG, Kopf AW, Bart RS, Rigel DS. Basal cell and squamous cell carcinomas are important risk factors for cutaneous malignant melanoma. Screening implications. Cancer. 1995;75(2 Suppl):707-14.
    • (1995) Cancer , vol.75 , Issue.2 , pp. 707-714
    • Marghoob, A.A.1    Slade, J.2    Salopek, T.G.3    Kopf, A.W.4    Bart, R.S.5    Rigel, D.S.6
  • 34
    • 33644840579 scopus 로고    scopus 로고
    • Comparison of risk patterns in carcinoma and melanoma of the skin in men: A multi-centre case-case-control study
    • Zanetti R, Rosso S, Martinez C, Nieto A, Miranda A, Mercier M, et al. Comparison of risk patterns in carcinoma and melanoma of the skin in men: a multi-centre case-case-control study. Br J Cancer. 2006;94(5):743-51.
    • (2006) Br J Cancer , vol.94 , Issue.5 , pp. 743-751
    • Zanetti, R.1    Rosso, S.2    Martinez, C.3    Nieto, A.4    Miranda, A.5    Mercier, M.6
  • 35
    • 0028899615 scopus 로고
    • Does intermittent sun exposure cause basal cell carcinoma? A case-control study in western Australia
    • Kricker A, Armstrong BK, English DR, Heenan PJ. Does intermittent sun exposure cause basal cell carcinoma? a case-control study in western Australia. int J Cancer. 1995;60(4):489-94.
    • (1995) Int J Cancer. , vol.60 , Issue.4 , pp. 489-494
    • Kricker, A.1    Armstrong, B.K.2    English, D.R.3    Heenan, P.J.4
  • 36
    • 84858335295 scopus 로고    scopus 로고
    • The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: A 30-year prospective study
    • PUvA Follow-Up Study
    • Stern RS, PUvA Follow-Up Study. The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: a 30-year prospective study. J Am Acad Dermatol. 2012;66(4):553-62.
    • (2012) J am Acad Dermatol , vol.66 , Issue.4 , pp. 553-562
    • Stern, R.S.1
  • 39
    • 84880332193 scopus 로고    scopus 로고
    • Photosensitizing agents and the risk of non-melanoma skin cancer: A population-based case-control study
    • Robinson SN, Zens MS, Perry AE, Spencer SK, Duell EJ, Karagas MR. Photosensitizing agents and the risk of non-melanoma skin cancer: a population-based case-control study. J invest Dermatol. 2013;133(8):1950-5.
    • (2013) J Invest Dermatol , vol.133 , Issue.8 , pp. 1950-1955
    • Robinson, S.N.1    Zens, M.S.2    Perry, A.E.3    Spencer, S.K.4    Duell, E.J.5    Karagas, M.R.6
  • 40
    • 0030463164 scopus 로고    scopus 로고
    • Risk of basal cell and squamous cell skin cancers after ionizing radiation therapy. For The Skin Cancer Prevention Study Group
    • Karagas MR, McDonald JA, Greenberg ER, Stukel TA, weiss JE, Baron JA, et al. Risk of basal cell and squamous cell skin cancers after ionizing radiation therapy. For The Skin Cancer Prevention Study Group. J Natl Cancer inst. 1996;88(24):1848-53.
    • (1996) J Natl Cancer Inst , vol.88 , Issue.24 , pp. 1848-1853
    • Karagas, M.R.1    McDonald, J.A.2    Greenberg, E.R.3    Stukel, T.A.4    Weiss, J.E.5    Baron, J.A.6
  • 42
    • 0033776581 scopus 로고    scopus 로고
    • Basal cell carcinoma in chronic arsenicism occurring in Queensland, Australia, after ingestion of an asthma medication
    • Boonchai W, Green A, Ng J, Dicker A, Chenevix-Trench G. Basal cell carcinoma in chronic arsenicism occurring in Queensland, Australia, after ingestion of an asthma medication. J Am Acad Dermatol. 2000;43(4):664-9.
    • (2000) J am Acad Dermatol , vol.43 , Issue.4 , pp. 664-669
    • Boonchai, W.1    Green, A.2    Ng, J.3    Dicker, A.4    Chenevix-Trench, G.5
  • 43
    • 0345062135 scopus 로고    scopus 로고
    • Dietary arsenic intakes in the United States: FDA Total Diet Study, September 1991-December 1996
    • Tao SS, Bolger PM. Dietary arsenic intakes in the United States: FDA Total Diet Study, September 1991-December 1996. Food Addit Contam. 1999;16(11):465-72.
    • (1999) Food Addit Contam , vol.16 , Issue.11 , pp. 465-472
    • Tao, S.S.1    Bolger, P.M.2
  • 44
    • 0037464506 scopus 로고    scopus 로고
    • Skin cancers after organ transplantation
    • Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med. 2003;348(17):1681-91.
    • (2003) N Engl J Med , vol.348 , Issue.17 , pp. 1681-1691
    • Euvrard, S.1    Kanitakis, J.2    Claudy, A.3
  • 46
    • 0033928027 scopus 로고    scopus 로고
    • Tumors arising in nevus sebaceus: A study of 596 cases
    • Cribier B, Scrivener Y, Grosshans E. Tumors arising in nevus sebaceus: A study of 596 cases. J Am Acad Dermatol. 2000;42(2 Pt 1):263-8.
    • (2000) J am Acad Dermatol , vol.42 , Issue.2 , pp. 263-268
    • Cribier, B.1    Scrivener, Y.2    Grosshans, E.3
  • 48
    • 0022595988 scopus 로고
    • Risk reduction for non-melanoma skin cancer with childhood sunscreen use
    • Stern RS, weinstein MC, Baker SG. Risk reduction for non-melanoma skin cancer with childhood sunscreen use. Arch Dermatol. 1986;122(5):537-45.
    • (1986) Arch Dermatol , vol.122 , Issue.5 , pp. 537-545
    • Stern, R.S.1    Weinstein, M.C.2    Baker, S.G.3
  • 49
    • 0033612873 scopus 로고    scopus 로고
    • Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: A randomised controlled trial
    • Green A, williams G, Neale R, Hart V, Leslie D, Parsons P, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet. 1999;354(9180):723-9.
    • (1999) Lancet , vol.354 , Issue.9180 , pp. 723-729
    • Green, A.1    Williams, G.2    Neale, R.3    Hart, V.4    Leslie, D.5    Parsons, P.6
  • 50
    • 70349312806 scopus 로고    scopus 로고
    • Prevention of non-melanoma skin cancer in organ transplant patients by regular use of a sunscreen: A 24 months, prospective, case-control study
    • Ulrich C, Jurgensen JS, Degen A, Hackethal M, Ulrich M, Patel MJ, et al. Prevention of non-melanoma skin cancer in organ transplant patients by regular use of a sunscreen: a 24 months, prospective, case-control study. Br J Dermatol. 2009;161 Suppl 3:78-84.
    • (2009) Br J Dermatol , vol.161 , pp. 78-84
    • Ulrich, C.1    Jurgensen, J.S.2    Degen, A.3    Hackethal, M.4    Ulrich, M.5    Patel, M.J.6
  • 51
    • 0036062775 scopus 로고    scopus 로고
    • Variations of basal cell
    • Scrivener Y, Grosshans E, Cribier B. variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002;147(1):41-7.
    • (2002) Br J Dermatol , vol.147 , Issue.1 , pp. 41-47
    • Scrivener, Y.1    Grosshans, E.2    Cribier, B.3
  • 52
    • 84882251352 scopus 로고    scopus 로고
    • Actinic Keratosis, Basal Cell Carcinoma and Squamous Cell Carcinoma
    • in: Bolog-nia JL, Jorizzo JL, Schaffer J v, editors, 3rd edition. Saunders
    • Soyer HP, Rigel DS, wurm EM. Actinic Keratosis, Basal Cell Carcinoma and Squamous Cell Carcinoma. in: Bolog-nia JL, Jorizzo JL, Schaffer J v, editors. Dermatology. 3rd edition. Saunders; 2012. p. 1773-93.
    • (2012) Dermatology , pp. 1773-1793
    • Soyer, H.P.1    Rigel, D.S.2    Wurm, E.M.3
  • 54
    • 0030924338 scopus 로고    scopus 로고
    • Differences in age
    • McCormack CJ, Kelly JW, Dorevitch AP. Differences in age and body site distribution of the histological subtypes of basal cell carcinoma. A possible indicator of differing causes. Arch Dermatol. 1997;133(5):593-6.
    • (1997) Arch Dermatol , vol.133 , Issue.5 , pp. 593-596
    • McCormack, C.J.1    Kelly, J.W.2    Dorevitch, A.P.3
  • 55
    • 84930162714 scopus 로고    scopus 로고
    • UpToDate [internet]. Available from:
    • Wu PA. Epidemiology and clinical features of basal cell carcinoma 2014. UpToDate [internet]. Available from: http://www.uptodate.com/contents/epidemiology-and-clini-cal-features-of-basal-cell-carcinoma.
    • Epidemiology and Clinical Features of Basal Cell Car
    • Wu, P.A.1
  • 56
    • 71949115204 scopus 로고    scopus 로고
    • Dermatoscopy of basal cell carcinoma: Morphologic variability of global and local features and accuracy of diagnosis
    • Altamura D, Menzies SW, Argenziano G, Zalaudek I, Soyer H P, Sera F, et al. Dermatoscopy of basal cell carcinoma: morphologic variability of global and local features and accuracy of diagnosis. J Am Acad Dermatol. 2010;62(1):67-75.
    • (2010) J am Acad Dermatol , vol.62 , Issue.1 , pp. 67-75
    • Altamura, D.1    Menzies, S.W.2    Argenziano, G.3    Zalaudek, I.4    Soyer, H.P.5    Sera, F.6
  • 57
    • 77955866506 scopus 로고    scopus 로고
    • How to diagnose nonpigmented skin tumors: A review of vascular structures seen with dermoscopy: Part ii. Nonmelanocytic skin tumors
    • quiz 87-8
    • Zalaudek I, Kreusch J, Giacomel J, Ferrara G, Catricala C, Argenziano G. How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part ii. Nonmelanocytic skin tumors. J Am Acad Dermatol. 2010;63(3):377-86; quiz 87-8.
    • (2010) J am Acad Dermatol , vol.63 , Issue.3 , pp. 377-386
    • Zalaudek, I.1    Kreusch, J.2    Giacomel, J.3    Ferrara, G.4    Catricala, C.5    Argenziano, G.6
  • 58
    • 0032784453 scopus 로고    scopus 로고
    • Basal cell carcinoma: A comparison of shave biopsy versus punch biopsy techniques in subtype diagnosis
    • Russell EB, Carrington PR, Smoller BR. Basal cell carcinoma: a comparison of shave biopsy versus punch biopsy techniques in subtype diagnosis. J Am Acad Dermatol. 1999;41(1):69-71.
    • (1999) J am Acad Dermatol , vol.41 , Issue.1 , pp. 69-71
    • Russell, E.B.1    Carrington, P.R.2    Smoller, B.R.3
  • 59
    • 83655163878 scopus 로고    scopus 로고
    • Accuracy of biopsy sampling for subtyping basal cell carcinoma
    • Haws AL, Rojano R, Tahan SR, Phung TL. Accuracy of biopsy sampling for subtyping basal cell carcinoma. J Am Acad Dermatol. 2012;66(1):106-11.
    • (2012) J am Acad Dermatol , vol.66 , Issue.1 , pp. 106-111
    • Haws, A.L.1    Rojano, R.2    Tahan, S.R.3    Phung, T.L.4
  • 61
    • 84880512835 scopus 로고    scopus 로고
    • High discordance between punch biopsy and excision in establishing basal cell carcinoma subtype: Analysis of 500 cases
    • wolberink EA, Pasch MC, Zeiler M, van Erp PE, Gerritsen MJ. High discordance between punch biopsy and excision in establishing basal cell carcinoma subtype: analysis of 500 cases. J Eur Acad Dermatol venereol. 2013;27(8):985-9.
    • (2013) J Eur Acad Dermatol Venereol , vol.27 , Issue.8 , pp. 985-989
    • Wolberink, E.A.1    Pasch, M.C.2    Zeiler, M.3    Van Erp, P.E.4    Gerritsen, M.J.5
  • 62
    • 0025689106 scopus 로고
    • Histologic pattern analysis of basal cell carcinoma. Study of a series of 1039 consecutive neoplasms
    • Sexton M, Jones DB, Maloney ME. Histologic pattern analysis of basal cell carcinoma. Study of a series of 1039 consecutive neoplasms. J Am Acad Dermatol. 1990;23(6 Pt 1):1118-26.
    • (1990) J am Acad Dermatol , vol.23 , Issue.6 , pp. 1118-1126
    • Sexton, M.1    Jones, D.B.2    Maloney, M.E.3
  • 63
    • 31644445651 scopus 로고    scopus 로고
    • Basal cell carcinoma: Biology, morphology and clinical implications
    • Crowson AN. Basal cell carcinoma: biology, morphology and clinical implications. Mod Pathol. 2006;19 Suppl 2:S127-47.
    • (2006) Mod Pathol. , vol.19 , pp. S127-S247
    • Crowson, A.N.1
  • 66
  • 67
    • 0024583768 scopus 로고
    • Mohs surgery is the treatment of choice for recurrent (previously treated) basal cell carcinoma
    • Rowe DE, Carroll RJ, Day CL Jr. Mohs surgery is the treatment of choice for recurrent (previously treated) basal cell carcinoma. J Dermatol Surg Oncol. 1989;15(4):424-31.
    • (1989) J Dermatol Surg Oncol , vol.15 , Issue.4 , pp. 424-431
    • Rowe, D.E.1    Carroll, R.J.2    Day, C.L.3
  • 68
    • 84876586267 scopus 로고    scopus 로고
    • Tumor recurrence 5 years after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma
    • Chren MM, Linos E, Torres JS, Stuart SE, Parvataneni R, Boscardin WJ. Tumor recurrence 5 years after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma. J invest Dermatol. 2013;133(5):1188-96.
    • (2013) J Invest Dermatol , vol.133 , Issue.5 , pp. 1188-1196
    • Chren, M.M.1    Linos, E.2    Torres, J.S.3    Stuart, S.E.4    Parvataneni, R.5    Boscardin, W.J.6
  • 69
    • 84877764756 scopus 로고    scopus 로고
    • Recurrence rates of aggressive histologic types of basal cell carcinoma after treatment with electrodesiccation and curettage alone
    • Blixt E, Nelsen D, Stratman E. Recurrence rates of aggressive histologic types of basal cell carcinoma after treatment with electrodesiccation and curettage alone. Dermatol Surg. 2013;39(5):719-25.
    • (2013) Dermatol Surg , vol.39 , Issue.5 , pp. 719-725
    • Blixt, E.1    Nelsen, D.2    Stratman, E.3
  • 71
    • 0023153898 scopus 로고
    • Surgical margins for basal cell carcinoma
    • wolf DJ, Zitelli JA. Surgical margins for basal cell carcinoma. Arch Dermatol. 1987;123(3):340-4.
    • (1987) Arch Dermatol , vol.123 , Issue.3 , pp. 340-344
    • Wolf, D.J.1    Zitelli, J.A.2
  • 76
    • 0020538980 scopus 로고
    • Multivariate risk score for recurrence of cutaneous basal cell carcinomas
    • Dubin N, Kopf AW. Multivariate risk score for recurrence of cutaneous basal cell carcinomas. Arch Dermatol. 1983;119(5):373-7.
    • (1983) Arch Dermatol , vol.119 , Issue.5 , pp. 373-377
    • Dubin, N.1    Kopf, A.W.2
  • 77
    • 56449129112 scopus 로고    scopus 로고
    • Surgical excision versus Mohs’ mi-crographic surgery for primary and recurrent basal-cell carcinoma of the face: A prospective randomised controlled trial with 5-years’ follow-up
    • Mosterd K, Krekels GA, Nieman FH, Ostertag JU, Essers BA, Dirksen CD, et al. Surgical excision versus Mohs’ mi-crographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years’ follow-up. Lancet Oncol. 2008;9(12):1149-56.
    • (2008) Lancet Oncol , vol.9 , Issue.12 , pp. 1149-1156
    • Mosterd, K.1    Krekels, G.A.2    Nieman, F.H.3    Ostertag, J.U.4    Essers, B.A.5    Dirksen, C.D.6
  • 78
    • 23944462707 scopus 로고    scopus 로고
    • Basal cell carcinoma treated with Mohs surgery in Australiaii. Outcome at 5-year follow-up
    • Leibovitch I, Huilgol SC, Selva D, Richards S, Paver R. Basal cell carcinoma treated with Mohs surgery in Australia ii. Outcome at 5-year follow-up. J Am Acad Dermatol. 2005;53(3):452-7.
    • (2005) J am Acad Dermatol , vol.53 , Issue.3 , pp. 452-457
    • Leibovitch, I.1    Huilgol, S.C.2    Selva, D.3    Richards, S.4    Paver, R.5
  • 79
    • 0036342215 scopus 로고    scopus 로고
    • Predictors of extensive subclinical spread in nonmelanoma skin cancer treated with Mohs mi-crographic surgery
    • Batra RS, Kelley LC. Predictors of extensive subclinical spread in nonmelanoma skin cancer treated with Mohs mi-crographic surgery. Arch Dermatol. 2002;138(8):1043-51.
    • (2002) Arch Dermatol , vol.138 , Issue.8 , pp. 1043-1051
    • Batra, R.S.1    Kelley, L.C.2
  • 80
    • 23944501106 scopus 로고    scopus 로고
    • Basal cell carcinoma treated with Mohs surgery in Australia iii. Per-
    • Leibovitch I, Huilgol SC, Selva D, Richards S, Paver R. Basal cell carcinoma treated with Mohs surgery in Australia iii. Per-ineural invasion. J Am Acad Dermatol. 2005;53(3):458-63.
    • (2005) J am Acad Dermatol , vol.53 , Issue.3 , pp. 458-463
    • Leibovitch, I.1    Huilgol, S.C.2    Selva, D.3    Richards, S.4    Paver, R.5
  • 81
    • 69949175699 scopus 로고    scopus 로고
    • Randomized comparison of Mohs micrographic surgery and surgical excision for small nodular basal cell carcinoma: Tissue-sparing outcome
    • Muller FM, Dawe RS, Moseley H, Fleming CJ. Randomized comparison of Mohs micrographic surgery and surgical excision for small nodular basal cell carcinoma: tissue-sparing outcome. Dermatol Surg. 2009;35(9):1349-54.
    • (2009) Dermatol Surg , vol.35 , Issue.9 , pp. 1349-1354
    • Muller, F.M.1    Dawe, R.S.2    Moseley, H.3    Fleming, C.J.4
  • 82
    • 0031795693 scopus 로고    scopus 로고
    • Mohs micrographic surgery: A cost analysis
    • Cook J, Zitelli JA. Mohs micrographic surgery: a cost analysis. J Am Acad Dermatol. 1998;39(5 Pt 1):698-703.
    • (1998) J am Acad Dermatol , vol.39 , Issue.5 , pp. 698-703
    • Cook, J.1    Zitelli, J.A.2
  • 84
    • 84866378247 scopus 로고    scopus 로고
    • AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: A report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Derma-tologic Surgery Association, and the American Society for Mohs Surgery
    • Ad Hoc Task Force,
    • Connolly SM, Baker DR, Coldiron BM, Fazio MJ, Storrs PA, et al. Ad Hoc Task Force, AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: a report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Derma-tologic Surgery Association, and the American Society for Mohs Surgery. J Am Acad Dermatol. 2012;67(4):531-50.
    • (2012) J am Acad Dermatol , vol.67 , Issue.4 , pp. 531-550
    • Connolly, S.M.1    Baker, D.R.2    Coldiron, B.M.3    Fazio, M.J.4    Storrs, P.A.5
  • 86
    • 0041920772 scopus 로고    scopus 로고
    • Tumor-selective induction of apoptosisand the small-molecule immune response modifier im-iquimod
    • Schon M, Bong AB, Drewniok C, Herz J, Geilen CC, Reifenberger J, et al. Tumor-selective induction of apoptosis and the small-molecule immune response modifier im-iquimod. J Natl Cancer inst. 2003;95(15):1138-49.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.15 , pp. 1138-1149
    • Schon, M.1    Bong, A.B.2    Drewniok, C.3    Herz, J.4    Geilen, C.C.5    Reifenberger, J.6
  • 87
    • 2342473348 scopus 로고    scopus 로고
    • Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: Results from two phase iii, randomized, vehicle-controlled studies
    • Geisse J, Caro I, Lindholm J, Golitz L, Stampone P, Owens M. imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase iii, randomized, vehicle-controlled studies. J Am Acad Dermatol. 2004;50(5):722-33.
    • (2004) J am Acad Dermatol , vol.50 , Issue.5 , pp. 722-733
    • Geisse, J.1    Caro, I.2    Lindholm, J.3    Golitz, L.4    Stampone, P.5    Owens, M.6
  • 88
    • 34548531036 scopus 로고    scopus 로고
    • A phase iii, randomized, open label study to evaluate the safety and efficacy of imiquimod 5% cream applied thrice weekly for 8 and 12 weeks in the treatment of low-risk nodular basal cell carcinoma
    • Eigentler TK, Kamin A, weide BM, Breuninger H, Caroli UM, Mohrle M, et al. A phase iii, randomized, open label study to evaluate the safety and efficacy of imiquimod 5% cream applied thrice weekly for 8 and 12 weeks in the treatment of low-risk nodular basal cell carcinoma. J Am Acad Dermatol. 2007;57(4):616-21.
    • (2007) J am Acad Dermatol , vol.57 , Issue.4 , pp. 616-621
    • Eigentler, T.K.1    Kamin, A.2    Weide, B.M.3    Breuninger, H.4    Caroli, U.M.5    Mohrle, M.6
  • 89
    • 0033916806 scopus 로고    scopus 로고
    • The use of imiquimod 5% cream for the treatment of superficial basal cell carcinomas in a basal cell nevus syndrome patient
    • discussion 8-9
    • Kagy MK, Amonette R. The use of imiquimod 5% cream for the treatment of superficial basal cell carcinomas in a basal cell nevus syndrome patient. Dermatol Surg. 2000;26(6):577-8; discussion 8-9.
    • (2000) Dermatol Surg , vol.26 , Issue.6 , pp. 577-578
    • Kagy, M.K.1    Amonette, R.2
  • 90
    • 0036860972 scopus 로고    scopus 로고
    • Successful treatment of basal cell carcinomas in a nevoid basal cell carcinoma syndrome with topical 5% imiquimod
    • Stockfleth E, Ulrich C, Hauschild A, Lischner S, Meyer T, Christophers E. Successful treatment of basal cell carcinomas in a nevoid basal cell carcinoma syndrome with topical 5% imiquimod. Eur J Dermatol. 2002;12(6):569-72.
    • (2002) Eur J Dermatol , vol.12 , Issue.6 , pp. 569-572
    • Stockfleth, E.1    Ulrich, C.2    Hauschild, A.3    Lischner, S.4    Meyer, T.5    Christophers, E.6
  • 91
    • 0036288305 scopus 로고    scopus 로고
    • Therapeutic response of a brother and sister with xeroderma pigmentosum to im-iquimod 5% cream
    • weisberg NK, varghese M. Therapeutic response of a brother and sister with xeroderma pigmentosum to im-iquimod 5% cream. Dermatol Surg. 2002;28(6):518-23.
    • (2002) Dermatol Surg , vol.28 , Issue.6 , pp. 518-523
    • Weisberg, N.K.1    Varghese, M.2
  • 92
    • 33746276154 scopus 로고    scopus 로고
    • Hundreds of basal cell carcinomas in a Gorlin-Goltz syndrome patient cured with imiquimod 5% cream
    • Ferreres JR, Macaya A, Jucgla A, Muniesa C, Prats C, Peyri J. Hundreds of basal cell carcinomas in a Gorlin-Goltz syndrome patient cured with imiquimod 5% cream. J Eur Acad Dermatol venereol. 2006;20(7):877-8.
    • (2006) J Eur Acad Dermatol Venereol , vol.20 , Issue.7 , pp. 877-878
    • Ferreres, J.R.1    Macaya, A.2    Jucgla, A.3    Muniesa, C.4    Prats, C.5    Peyri, J.6
  • 94
    • 84880510597 scopus 로고    scopus 로고
    • Photodynamic therapy using topical 5-aminolaevulinic acid vs. Surgery for basal cell carcinoma
    • Cosgarea R, Susan M, Crisan M, Senila S. Photodynamic therapy using topical 5-aminolaevulinic acid vs. surgery for basal cell carcinoma. J Eur Acad Dermatol venereol. 2013;27(8):980-4.
    • (2013) J Eur Acad Dermatol Venereol , vol.27 , Issue.8 , pp. 980-984
    • Cosgarea, R.1    Susan, M.2    Crisan, M.3    Senila, S.4
  • 95
    • 84867063990 scopus 로고    scopus 로고
    • Overall treatment success after treatment of primary superficial basal cell carcinoma: A systematic review and meta-
    • Roozeboom MH, Arits AH, Nelemans PJ, Kelleners-Smeets NW. Overall treatment success after treatment of primary superficial basal cell carcinoma: a systematic review and meta-analysis of randomized and nonrandomized trials. Br J Dermatol. 2012;167(4):733-56.
    • (2012) Br J Dermatol , vol.167 , Issue.4 , pp. 733-756
    • Roozeboom, M.H.1    Arits, A.H.2    Nelemans, P.J.3    Kelleners-Smeets, N.W.4
  • 96
    • 84878346748 scopus 로고    scopus 로고
    • Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: A single blind, non-inferiority, randomised controlled trial
    • Arits AH, Mosterd K, Essers BA, Spoorenberg E, Sommer A, De Rooij MJ, et al. Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: a single blind, non-inferiority, randomised controlled trial. Lancet Oncol. 2013;14(7):647-54.
    • (2013) Lancet Oncol , vol.14 , Issue.7 , pp. 54
    • Arits, A.H.1    Mosterd, K.2    Essers, B.A.3    Spoorenberg, E.4    Sommer, A.5    De Rooij, M.J.6
  • 97
    • 0021243643 scopus 로고
    • Metastatic basal cell carcinoma.
    • von Domarus H, Stevens PJ. Metastatic basal cell carcinoma. Report of five cases and review of 170 cases in the literature. J Am Acad Dermatol. 1984;10(6):1043-60.
    • (1984) J am Acad Dermatol , vol.10 , Issue.6 , pp. 1043-1060
    • Von Domarus, H.1    Stevens, P.J.2
  • 99
    • 84890796086 scopus 로고    scopus 로고
    • Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib
    • Chang AL, Solomon JA, Hainsworth JD, Goldberg L, McKenna E, Day BM, et al. Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib. J Am Acad Der-matol. 2014;70(1):60-9.
    • (2014) J am Acad Der-Matol , vol.70 , Issue.1 , pp. 60-69
    • Chang, A.L.1    Solomon, J.A.2    Hainsworth, J.D.3    Goldberg, L.4    McKenna, E.5    Day, B.M.6
  • 101
    • 79960340656 scopus 로고    scopus 로고
    • Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor
    • Skvara H, Kalthoff F, Meingassner JG, wolff-winiski B, Aschauer H, Kelleher JF, et al. Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor. J invest Dermatol. 2011;131(8):1735-44.
    • (2011) J Invest Dermatol , vol.131 , Issue.8 , pp. 1735-1744
    • Skvara, H.1    Kalthoff, F.2    Meingassner, J.G.3    Wolff-Winiski, B.4    Aschauer, H.5    Kelleher, J.F.6
  • 102
    • 79955990024 scopus 로고    scopus 로고
    • Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened
    • Tang T, Tang JY, Li D, Reich M, Callahan CA, Fu L, et al. Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened. Clin Cancer Res. 2011;17(10):3378-87.
    • (2011) Clin Cancer Res , vol.17 , Issue.10 , pp. 3378-3387
    • Tang, T.1    Tang, J.Y.2    Li, D.3    Reich, M.4    Callahan, C.A.5    Fu, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.