Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles

Nanomedicine

Volumn 10, Issue 10, 2015, Pages 1569-1583

  Chaturvedi, Kiran ^a   Ganguly, Kuntal ^a   Kulkarni, Anandrao R ^a   Rudzinski, Walter E ^b   Krauss, Leslie ^c   Nadagouda, Mallikarjuna N ^a   Aminabhavi, Tejraj M ^a  

^a Soniya Education Trust's College of Pharmacy   (India)

^b Texas State University   (United States)

^c Cytoviva Inc   (United States)

Author keywords

deoxycholic acid; insulin; nanoparticles; polyethylene glycol; polyhydroxybutyrate

Indexed keywords

COPOLYMER; DEOXYCHOLIC ACID; EUDRAGIT; FLUORESCEIN ISOTHIOCYANATE; HYDROXYBUTYRIC ACID; INSULIN; NANOPARTICLE; PEGYLATED POLYHYDROXYBUTYRATE; RHODAMINE 123; UNCLASSIFIED DRUG; BUTYRIC ACID; DRUG CARRIER; MACROGOL DERIVATIVE;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETES MELLITUS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG UPTAKE; ENTERIC COATED TABLET; GEL PERMEATION CHROMATOGRAPHY; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MAXIMUM PLASMA CONCENTRATION; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; THERMOGRAVIMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL; CHEMISTRY; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; BUTYRIC ACID; CALORIMETRY, DIFFERENTIAL SCANNING; DEOXYCHOLIC ACID; DRUG CARRIERS; INSULIN; NANOPARTICLES; POLYETHYLENE GLYCOLS; THERMOGRAVIMETRY;

EID: 84930160627     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.15.36     Document Type: Article

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