Blend microspheres of poly(3-hydroxybutyrate) and cellulose acetate phthalate for colon delivery of 5-fluorouracil

Industrial and Engineering Chemistry Research

Volumn 50, Issue 18, 2011, Pages 10414-10423

  Chaturvedi, Kiran ^a   Kulkarni, Anandrao R ^a   Aminabhavi, Tejraj M ^a  

^a S E T S COLLEGE OF PHARMACY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5-FLUOROURACIL; 5-FLUOROURACIL (5-FU); ANTICANCER DRUG; BUFFER MEDIUM; CELLULOSE ACETATE PHTHALATE; COLON DELIVERY; CRYSTALLINE NATURE; DRUG RELEASE; DRUG-POLYMER INTERACTION; EMPIRICAL EQUATIONS; FOURIER TRANSFORM INFRARED; IN-VITRO; INTESTINAL MEDIUM; MATRIX; MOLECULAR LEVELS; PH SENSITIVE; PH-DEPENDENT; POLY(3-HYDROXYBUTYRATE); POLYMER BLEND COMPATIBILITY; SOLVENT EVAPORATION TECHNIQUES;

CELLULOSE; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG INTERACTIONS; ESTERS; EXPERIMENTS; FOURIER TRANSFORMS; POLYMER BLENDS; SCANNING ELECTRON MICROSCOPY; VOLATILE FATTY ACIDS;

MICROSPHERES;

EID: 80052861854     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie2011005     Document Type: Article

References (35)

1. Mundargi, R. C.; Babu, V. R.; Rangaswamy, V.; Patel, P.; Aminabhavi, T. M. Nano/micro technologies for delivering macromolecular therapeutics using poly(d, l -lactide- co -glycolide) and its derivatives J. Controlled Release 2008, 125, 193
2. Liang, H. F.; Chen, S. C.; Chen, M. C.; Lee, P. W.; Chen, C. T.; Sung, H. W. Paclitaxel-loaded poly(γ-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system against cultured HepG2 cells Bioconjugate Chem. 2006, 7, 291
3. Avgoustakis, K. Pegylated poly(lactide) and poly(lactide- co -glycolide) nanoparticles: Preparation, properties and possible applications in drug delivery Current Drug Delivery 2004, 1, 321
4. Thakkar, H.; Sharma, R. K.; Mishra, A. K.; Chuttani, K.; Murthy, R. R. Albumin microspheres as carriers for the antiarthritic drug celecoxib AAPS Pharm. Sci. Technol. 2005, 6, E65
5. Agnihotri, S. A.; Mallikarjuna, N. N.; Aminabhavi, T. M. Recent advances on chitosan-based micro and nanoparticles in drug delivery J. Controlled Release 2004, 100, 5
6. Kumbar, S. G.; Kulkarni, A. R.; Aminabhavi, T. M. Crosslinked chitosan microspheres for encapsulation of diclofenac sodium: Effect of crosslinking agent J. Microencapsulation 2002, 19, 173
7. Kulkarni, A. R.; Soppimath, K. S.; Aminabhavi, T. M.; Rudzinski, W. E. In vitro release kinetics of cefadroxil-loaded sodium alginate interpenetrating network beads Eur. J. Pharm. Biopharm. 2001, 51, 127
8. Sendil, D.; Gursel, I.; Wise, D. L.; Hasirci, V. Antibiotic release from biodegradable PHBV microparticles J. Controlled Release 1999, 59, 207
9. Zhao, K.; Deng, Y.; Chen, J. C.; Chen, G. Q. Polyhydroxyalkanoate (PHA) scaffolds with good mechanical properties and biocompatibility Biomaterials 2003, 24, 1041
10. Valappil, S. P.; Misra, S. K.; Boccaccini, A. R.; Roy, I. Biomedical applications of polyhydroxyalkanoates, an overview of animal testing and in vivo responses Expert Rev. Med. Devices 2006, 3, 853
11. Chen, G. Q.; Wu, Q. The application of polyhydroxyalkanoate as tissue engineering materials Biomaterials 2005, 26, 6565
12. Homes, P. A. Applications of PHB: A microbially produced thermoplastic Phys. Technol. 1985, 16, 32
13. Doi, Y. Microbial Polyesters; VCH Publishers: New York, 1990; p 151.
14. Zhang, L.; Zheng, Z.; Xi, J.; Gao, Y.; Ao, Q.; Gong, Y.; Zhao, N.; Zhang, X. Improved mechanical property and biocompatibility of poly(3-hydroxybutyrate- co -3-hydroxyhexanoate) for blood vessel tissue engineering by blending with poly(propylene carbonate) Eur. Polym. J. 2007, 43, 2975
15. Nayak, A. P. Biodegradable polymers: Opportunities and challenges J. Macromol. Sci. Polym. Rev. 1999, C39, 481
16. Li, X. T.; Zhang, Y.; Chen, G. Q. Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials Biomaterials 2008, 29, 3720
17. Parra, D. F.; Fusaro, J.; Gaboardi, F.; Rosa, D. S. Influence of poly(ethylene glycol) on the thermal, mechanical, morphological, physicochemical and biodegradation properties of poly(3-hydroxybutyrate) Polym. Degrad. Stabil. 2006, 91, 1954
18. Yoshie, N.; Nakasato, K.; Fujiwara, M.; Kasuya, K.; Abe, H.; Doi, Y.; Inoue, Y. Effect of low molecular weight additives on enzymatic degradation of poly(3-hydroxybutyrate) Polymer 2000, 41, 3227
19. Goskonda, S. R.; Lee, J. C. Cellulose acetate phthalate. In Handbook of Pharmaceutical Excipients; Kibbe, A. H., Ed.; American Pharmaceutical Association/Pharmaceutical Press: Washington, D.C./London, 2000; p 99.
20. Wheatley, T. A.; Steuernagel, C. R. Latex emulsions for controlled drug delivery. In Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms; McGinity, J. W., Ed.; Marcel Dekker: New York, 1997; p 1.
21. Beyger, J. W.; Nairn, J. G. Some factors affecting the microencapsulation of pharmaceuticals with cellulose acetate phthalate J. Pharm. Sci. 1986, 75, 573
22. Dalmoro, A.; Lamberti, G.; Titomanlio, G.; Barba, A. A.; Amore, M. Enteric micro-particles for targeted oral drug delivery AAPS Pharm. Sci. Technol. 2010, 11, 1500
23. Grem, J. L. 5-Fluorinated pyrimidine. In Cancer Chemotherapy and Biotherapy. Principles and Practice; Chabner, B. A.; Longo, D. L., Eds.; Lippincott-Raven: Philadelphia, 1996; p 149.
24. Diasio, R. B.; Lu, Z. Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy J. Clin. Oncol. 1994, 12, 2239
25. Wei, H.; Qing, D.; De-Ying, C.; Bai, X.; Li-Fang, F. Study on colon-specific pectin/ethylcellulose film-coated 5-fluorouracil pellets in rats Int. J. Pharm. 2008, 348, 35
26. Friend, D. R. New oral delivery systems for treatment of inflammatory bowel disease Adv. Drug Delivery Rev. 2005, 57, 247
27. ®' system) J. Controlled Release 1997, 49, 115
28. Klein, S.; Stein, J.; Dressman, J. Site-specific delivery of anti-inflammatory drugs in the gastrointestinal tract: An in-vitro release model J. Pharm. Pharmacol. 2005, 57, 709
29. Jeong, Y. I.; Ohno, T.; Hu, Z.; Yoshikawa, Y.; Shibata, N.; Nagata, S.; Takada, K. Evaluation of an intestinal pressure-controlled colon delivery capsules prepared by a dipping method J. Controlled Release 2001, 71, 175
30. Xi, M. M.; Zhang, S. Q.; Wang, X. Y.; Fang, K. Q.; Gu, Y. Study on the characteristics of pectin-ketoprofen for colon targeting in rats Int. J. Pharm. 2005, 298, 91
31. Bazzo, G. C.; Lemos-Senna, E.; Gonçalves, M. C.; Pires, A. T. N. Effect of preparation conditions on morphology, drug content and release profiles of poly(hydroxybutyrate) microparticles containing piroxicam J. Braz. Chem. Soc. 2008, 19, 914
32. Barud, H. S.; Souza, J. L.; Santos, D. B.; Crespi, M. S.; Ribeiro, C. A.; Messaddeq, Y.; Ribeiro, S. J. L. Bacterial cellulose/poly(3-hydroxybutyrate) composite membranes Carbohydr. Polym. 2011, 83, 1279
33. Roxin, P.; Karlsson, A.; Singh, S. K. Characterization of cellulose acetate phthalate (CAP) Drug Dev. Ind. Pharm. 1998, 24, 1025
34. Barud, H. S.; de Araújo Júnior, A. M.; Santos, D. B.; de Assunção, R. M. N.; Meireles, C. S.; Cerqueira, D. A.; Filho, G. R.; Ribeiro, C. A.; Messaddeq, Y.; Ribeiro, S. J. L. Thermal behavior of cellulose acetate produced from homogeneous acetylation of bacterial cellulose Thermochim. Acta 2008, 471, 61
35. Lee, J. S.; Chae, G. S.; An, T. K.; Khang, G. Preparation of 5-fluorouracil-loaded poly(l -lactide- co -glycolide) wafer and evaluation of in vitro release behavior Macromol. Res. 2003, 11, 183