메뉴 건너뛰기




Volumn 6, Issue 14, 2015, Pages 12543-12557

miRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell carcinoma aggressive behaviour by targeting CAV1 and FLOT1

Author keywords

CAV1; FLOT1; Integrated analysis; MiR 124 3p; Renal cell carcinoma

Indexed keywords

CAVEOLIN 1; FLOTILLIN 1; MICRORNA; MICRORNA 124; MICRORNA 200C; MICRORNA 30A; UNCLASSIFIED DRUG; CAV1 PROTEIN, HUMAN; FLOTILLINS; MEMBRANE PROTEIN; MIRN124 MICRORNA, HUMAN; MIRN200 MICRORNA, HUMAN; MIRN30 MICRORNA, HUMAN;

EID: 84930017952     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3815     Document Type: Article
Times cited : (73)

References (50)
  • 1
    • 82955180319 scopus 로고    scopus 로고
    • Renal cell carcinoma
    • 6
    • Cairns P. Renal cell carcinoma. Cancer Biomark. 2010; 1-6: 461-473.
    • (2010) Cancer Biomark , vol.1 , pp. 461-473
    • Cairns, P.1
  • 6
    • 64549089259 scopus 로고    scopus 로고
    • Interlaboratory and interplatform comparison of microarray gene expression analysis of HepG2 cells exposed to benzo(a)pyrene
    • Hockley SL, Mathijs K, Staal YC, Brewer D, Giddings I, van Delft JH, Phillips DH. Interlaboratory and interplatform comparison of microarray gene expression analysis of HepG2 cells exposed to benzo(a)pyrene. OMICS. 2009; 2: 115-125.
    • (2009) OMICS , vol.2 , pp. 115-125
    • Hockley, S.L.1    Mathijs, K.2    Staal, Y.C.3    Brewer, D.4    Giddings, I.5    van Delft, J.H.6    Phillips, D.H.7
  • 8
    • 84872021010 scopus 로고    scopus 로고
    • Genomic medicine: new frontiers and new challenges
    • Pasic MD, Samaan S, Yousef GM. Genomic medicine: new frontiers and new challenges. Clin Chem. 2013; 1: 158-167.
    • (2013) Clin Chem , vol.1 , pp. 158-167
    • Pasic, M.D.1    Samaan, S.2    Yousef, G.M.3
  • 14
    • 84879637069 scopus 로고    scopus 로고
    • microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis
    • Wang X, Chen X, Wang R, Xiao P, Xu Z, Chen L, Hang W, Ruan A, Yang H, Zhang X. microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis. Oncol Rep. 2013; 2: 643-650.
    • (2013) Oncol Rep , vol.2 , pp. 643-650
    • Wang, X.1    Chen, X.2    Wang, R.3    Xiao, P.4    Xu, Z.5    Chen, L.6    Hang, W.7    Ruan, A.8    Yang, H.9    Zhang, X.10
  • 19
    • 84964314208 scopus 로고    scopus 로고
    • KITENIN-targeting MicroRNA-124 Suppresses Colorectal Cancer Cell Motility and Tumorigenesis
    • Park SY, Kim H, Yoon S, Bae JA, Choi SY, Jung YD, Kim KK. KITENIN-targeting MicroRNA-124 Suppresses Colorectal Cancer Cell Motility and Tumorigenesis. Mol Ther. 2014;.
    • (2014) Mol Ther
    • Park, S.Y.1    Kim, H.2    Yoon, S.3    Bae, J.A.4    Choi, S.Y.5    Jung, Y.D.6    Kim, K.K.7
  • 21
    • 84905174595 scopus 로고    scopus 로고
    • MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer
    • Xie L, Zhang Z, Tan Z, He R, Zeng X, Xie Y, Li S, Tang G, Tang H, He X. MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer. Mol Cell Biochem. 2014; 1-2: 153-159.
    • (2014) Mol Cell Biochem , vol.1-2 , pp. 153-159
    • Xie, L.1    Zhang, Z.2    Tan, Z.3    He, R.4    Zeng, X.5    Xie, Y.6    Li, S.7    Tang, G.8    Tang, H.9    He, X.10
  • 22
    • 84897018932 scopus 로고    scopus 로고
    • Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1
    • Wang P, Chen L, Zhang J, Chen H, Fan J, Wang K, Luo J, Chen Z, Meng Z, Liu L. Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1. Oncogene. 2014; 4: 514-524.
    • (2014) Oncogene , vol.4 , pp. 514-524
    • Wang, P.1    Chen, L.2    Zhang, J.3    Chen, H.4    Fan, J.5    Wang, K.6    Luo, J.7    Chen, Z.8    Meng, Z.9    Liu, L.10
  • 23
    • 84888849526 scopus 로고    scopus 로고
    • MicroRNA-124 suppresses growth of human hepatocellular carcinoma by targeting STAT3
    • Lu Y, Yue X, Cui Y, Zhang J, Wang K. MicroRNA-124 suppresses growth of human hepatocellular carcinoma by targeting STAT3. Biochem Biophys Res Commun. 2013; 4: 873-879.
    • (2013) Biochem Biophys Res Commun , vol.4 , pp. 873-879
    • Lu, Y.1    Yue, X.2    Cui, Y.3    Zhang, J.4    Wang, K.5
  • 24
    • 84928402297 scopus 로고    scopus 로고
    • Downregulation of microRNA-124 predicts poor prognosis in glioma patients
    • Chen T, Wang XY, Li C, Xu SJ. Downregulation of microRNA-124 predicts poor prognosis in glioma patients. Neurol Sci. 2014;.
    • (2014) Neurol Sci
    • Chen, T.1    Wang, X.Y.2    Li, C.3    Xu, S.J.4
  • 26
    • 0036479204 scopus 로고    scopus 로고
    • Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum
    • Le PU, Guay G, Altschuler Y, Nabi IR. Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum. J Biol Chem. 2002; 5: 3371-3379.
    • (2002) J Biol Chem , vol.5 , pp. 3371-3379
    • Le, P.U.1    Guay, G.2    Altschuler, Y.3    Nabi, I.R.4
  • 28
    • 0032483575 scopus 로고    scopus 로고
    • A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
    • Wary KK, Mariotti A, Zurzolo C, Giancotti FG. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell. 1998; 5: 625-634.
    • (1998) Cell , vol.5 , pp. 625-634
    • Wary, K.K.1    Mariotti, A.2    Zurzolo, C.3    Giancotti, F.G.4
  • 29
    • 0037018405 scopus 로고    scopus 로고
    • Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells
    • Fiucci G, Ravid D, Reich R, Liscovitch M. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene. 2002; 15: 2365-2375.
    • (2002) Oncogene , vol.15 , pp. 2365-2375
    • Fiucci, G.1    Ravid, D.2    Reich, R.3    Liscovitch, M.4
  • 34
    • 47249142436 scopus 로고    scopus 로고
    • Global analysis of metastasis-associated gene expression in primary cultures from clinical specimens of clear-cell renal-cell carcinoma
    • Tan X, Zhai Y, Chang W, Hou J, He S, Lin L, Yu Y, Xu D, Xiao J, Ma L, Wang G, Cao T, Cao G. Global analysis of metastasis-associated gene expression in primary cultures from clinical specimens of clear-cell renal-cell carcinoma. Int J Cancer. 2008; 5: 1080-1088.
    • (2008) Int J Cancer , vol.5 , pp. 1080-1088
    • Tan, X.1    Zhai, Y.2    Chang, W.3    Hou, J.4    He, S.5    Lin, L.6    Yu, Y.7    Xu, D.8    Xiao, J.9    Ma, L.10    Wang, G.11    Cao, T.12    Cao, G.13
  • 36
    • 30344486984 scopus 로고    scopus 로고
    • Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells
    • Glebov OO, Bright NA, Nichols BJ. Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells. Nat Cell Biol. 2006; 1: 46-54.
    • (2006) Nat Cell Biol , vol.1 , pp. 46-54
    • Glebov, O.O.1    Bright, N.A.2    Nichols, B.J.3
  • 37
    • 79956033520 scopus 로고    scopus 로고
    • Knockdown of FLOT1 impairs cell proliferation and tumorigenicity in breast cancer through upregulation of FOXO3a
    • Lin C, Wu Z, Lin X, Yu C, Shi T, Zeng Y, Wang X, Li J, Song L. Knockdown of FLOT1 impairs cell proliferation and tumorigenicity in breast cancer through upregulation of FOXO3a. Clin Cancer Res. 2011; 10: 3089-3099.
    • (2011) Clin Cancer Res , vol.10 , pp. 3089-3099
    • Lin, C.1    Wu, Z.2    Lin, X.3    Yu, C.4    Shi, T.5    Zeng, Y.6    Wang, X.7    Li, J.8    Song, L.9
  • 38
    • 84866660323 scopus 로고    scopus 로고
    • Flotillin-1 promotes tumor necrosis factor-alpha receptor signaling and activation of NF-kappaB in esophageal squamous cell carcinoma cells
    • Song L, Gong H, Lin C, Wang C, Liu L, Wu J, Li M, Li J. Flotillin-1 promotes tumor necrosis factor-alpha receptor signaling and activation of NF-kappaB in esophageal squamous cell carcinoma cells. Gastroenterology. 2012; 4: 995-1005.
    • (2012) Gastroenterology , vol.4 , pp. 995-1005
    • Song, L.1    Gong, H.2    Lin, C.3    Wang, C.4    Liu, L.5    Wu, J.6    Li, M.7    Li, J.8
  • 39
    • 84879472789 scopus 로고    scopus 로고
    • High Expression of FLOT1 Is Associated with Progression and Poor Prognosis in Hepatocellular Carcinoma
    • Zhang SH, Wang CJ, Shi L, Li XH, Zhou J, Song LB, Liao WT. High Expression of FLOT1 Is Associated with Progression and Poor Prognosis in Hepatocellular Carcinoma. PLoS One. 2013; 6: e64709-.
    • (2013) PLoS One , vol.6
    • Zhang, S.H.1    Wang, C.J.2    Shi, L.3    Li, X.H.4    Zhou, J.5    Song, L.B.6    Liao, W.T.7
  • 40
    • 84898825972 scopus 로고    scopus 로고
    • Abnormal expression of FLOT1 correlates with tumor progression and poor survival in patients with nonsmall cell lung cancer
    • Li H, Wang RM, Liu SG, Zhang JP, Luo JY, Zhang BJ, Zhang XG. Abnormal expression of FLOT1 correlates with tumor progression and poor survival in patients with nonsmall cell lung cancer. Tumour Biol. 2014; 4: 3311-3315.
    • (2014) Tumour Biol , vol.4 , pp. 3311-3315
    • Li, H.1    Wang, R.M.2    Liu, S.G.3    Zhang, J.P.4    Luo, J.Y.5    Zhang, B.J.6    Zhang, X.G.7
  • 41
    • 84857746692 scopus 로고    scopus 로고
    • Flotillin-1/reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling
    • Amaddii M, Meister M, Banning A, Tomasovic A, Mooz J, Rajalingam K, Tikkanen R. Flotillin-1/reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling. J Biol Chem. 2012; 10: 7265-7278.
    • (2012) J Biol Chem , vol.10 , pp. 7265-7278
    • Amaddii, M.1    Meister, M.2    Banning, A.3    Tomasovic, A.4    Mooz, J.5    Rajalingam, K.6    Tikkanen, R.7
  • 42
    • 84903279945 scopus 로고    scopus 로고
    • Flotillin-1 expression in human clear-cell renal cell carcinoma is associated with cancer progression and poor patient survival
    • Zhang Y, Li J, Song Y, Chen F, Pei Y, Yao F. Flotillin-1 expression in human clear-cell renal cell carcinoma is associated with cancer progression and poor patient survival. Mol Med Rep. 2014; 2: 860-866.
    • (2014) Mol Med Rep , vol.2 , pp. 860-866
    • Zhang, Y.1    Li, J.2    Song, Y.3    Chen, F.4    Pei, Y.5    Yao, F.6
  • 45
    • 79960610118 scopus 로고    scopus 로고
    • REVIGO summarizes and visualizes long lists of gene ontology terms
    • Supek F, Bosnjak M, Skunca N, Smuc T. REVIGO summarizes and visualizes long lists of gene ontology terms. PLoS One. 2011; 7: e21800-.
    • (2011) PLoS One , vol.7
    • Supek, F.1    Bosnjak, M.2    Skunca, N.3    Smuc, T.4
  • 50
    • 84877062871 scopus 로고    scopus 로고
    • Intracellular reactive oxidative stress, cell proliferation and apoptosis of Schwann cells on carbon nanofibrous substrates
    • Jain S, Webster TJ, Sharma A, Basu B. Intracellular reactive oxidative stress, cell proliferation and apoptosis of Schwann cells on carbon nanofibrous substrates. Biomaterials. 2013; 21: 4891-4901.
    • (2013) Biomaterials , vol.21 , pp. 4891-4901
    • Jain, S.1    Webster, T.J.2    Sharma, A.3    Basu, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.