Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling

Oncotarget

Volumn 6, Issue 14, 2015, Pages 12529-12542

  Yang, Yong Ryoul ^a   Kim, Dae Hyun ^a   Seo, Young Kyo ^a   Park, Dohyun ^b   Jang, Hyun Jun ^a,b   Choi, Soo Youn ^a   Lee, Yong Hwa ^a   Lee, Gyun Hui ^a   Nakajima, Kazuki ^c   Taniguchi, Naoyuki ^c   Kim, Jung Min ^a   Choi, Eun Jeong ^b   Moon, Hyo Youl ^a   Kim, Il Shin ^a   Choi, Jang Hyun ^a   Lee, Ho ^d   Ryu, Sung Ho ^b   Cocco, Lucio ^e   Suh, Pann Ghill ^a  

^a Ulsan National Institute of Science and Technology   (South Korea)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c RIKEN   (Japan)

^d National Cancer Center   (South Korea)

^e UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Colitis; Colitis associated cancer; O GlcNAcase; O GlcNAcylation

Indexed keywords

ACETYLGLUCOSAMINIDASE; AZOXYMETHANE; DEXTRAN SULFATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N ACETYLGLUCOSAMINYLTRANSFERASE; O LINKED BETA N ACETYLGLUCOSAMINE TRANSFERASE; O LINKED BETA N ACETYLGLUCOSAMINIDASE; SYNAPTOTAGMIN I; THREONINE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; BETA N ACETYLHEXOSAMINIDASE; HEXOSAMINIDASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLITIS ASSOCIATED CANCER; COLON CARCINOGENESIS; COLON TUMOR; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL TRANSFORMATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PROTEIN PROCESSING; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BETA-N-ACETYLHEXOSAMINIDASES; BLOTTING, WESTERN; CELL TRANSFORMATION, NEOPLASTIC; COLITIS; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-KAPPA B; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84930012265     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3725     Document Type: Article

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