메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages 331-343

The potential of cytotherapeutics in hematologic reconstitution and in the treatment and prophylaxis of graft-versus-host disease. Chapter I: Current practice and remaining unmet medical needs

Author keywords

graft versus host disease; GvHD; GvHD market estimate; hematopoietic stem cells; mesenchymal stem cells; NK cells; transplantation; Treg cells

Indexed keywords

ANTIFUNGAL AGENT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DACLIZUMAB; INFLIXIMAB; MYCOPHENOLATE MOFETIL; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 84930009212     PISSN: 17460751     EISSN: 1746076X     Source Type: Journal    
DOI: 10.2217/rme.15.12     Document Type: Review
Times cited : (7)

References (127)
  • 1
    • 0000970496 scopus 로고
    • Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy
    • Thomas ED, Lochte HL Jr, Lu WC, Ferrebee JW. Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N. Engl. J. Med. 257, 491-496 (1957).
    • (1957) N. Engl. J. Med. , vol.257 , pp. 491-496
    • Thomas, E.D.1    Lochte, H.L.2    Lu, W.C.3    Ferrebee, J.W.4
  • 2
    • 0017640510 scopus 로고
    • Current status of bone marrow transplantation for aplastic anemia and acute leukemia
    • Thomas ED, Fefer A, Buckner CD, Storb R. Current status of bone marrow transplantation for aplastic anemia and acute leukemia. Blood 49, 671-681 (1977).
    • (1977) Blood , vol.49 , pp. 671-681
    • Thomas, E.D.1    Fefer, A.2    Buckner, C.D.3    Storb, R.4
  • 3
    • 0017149264 scopus 로고
    • Aplastic anemia treated by allogeneic bone marrow transplantation: A report on 49 new cases from Seattle
    • Storb R, Thomas ED, Weiden PL et al. Aplastic anemia treated by allogeneic bone marrow transplantation: a report on 49 new cases from Seattle. Blood 48, 817-841 (1976).
    • (1976) Blood , vol.48 , pp. 817-841
    • Storb, R.1    Thomas, E.D.2    Weiden, P.L.3
  • 4
    • 77649181500 scopus 로고    scopus 로고
    • Allogeneic haematopoietic stem cell transplantation: Individualized stem cell and immune therapy of cancer
    • Jenq RR, van den Brink MR. Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer. Nat. Rev. Cancer 10, 213-221 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 213-221
    • Jenq, R.R.1    Van Den Brink, M.R.2
  • 6
    • 0036786302 scopus 로고    scopus 로고
    • Current trends in hematopoietic stem cell transplantation in Europe
    • Gratwohl A, Baldomero H, Horisberger B et al. Current trends in hematopoietic stem cell transplantation in Europe. Blood 100, 2374-2386 (2002).
    • (2002) Blood , vol.100 , pp. 2374-2386
    • Gratwohl, A.1    Baldomero, H.2    Horisberger, B.3
  • 7
    • 33646119401 scopus 로고    scopus 로고
    • Hematopoietic stem-cell transplantation
    • Copelan EA. Hematopoietic stem-cell transplantation. N. Engl. J. Med. 354, 1813-1826 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , pp. 1813-1826
    • Copelan, E.A.1
  • 8
    • 0036513663 scopus 로고    scopus 로고
    • History of haematopoietic stem-cell transplantation
    • Little MT, Storb R. History of haematopoietic stem-cell transplantation. Nat. Rev. Cancer 2, 231-238 (2002).
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 231-238
    • Little, M.T.1    Storb, R.2
  • 9
    • 35248899954 scopus 로고    scopus 로고
    • Hematopoietic-cell transplantation at 50
    • Appelbaum FR. Hematopoietic-cell transplantation at 50. N. Engl. J. Med. 357, 1472-1475 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 1472-1475
    • Appelbaum, F.R.1
  • 10
    • 0019831188 scopus 로고
    • Bone marrow transplantation for inborn errors
    • Hobbs JR. Bone marrow transplantation for inborn errors. Lancet 2, 735-739 (1981).
    • (1981) Lancet , vol.2 , pp. 735-739
    • Hobbs, J.R.1
  • 11
    • 0029634283 scopus 로고
    • Allogeneic bone marrow transplantation for lysosomal storage diseases the european group for bone marrow transplantation
    • Hoogerbrugge PM, Brouwer OF, Bordigoni P et al. Allogeneic bone marrow transplantation for lysosomal storage diseases. The European Group for Bone Marrow Transplantation. Lancet 345, 1398-1402 (1995).
    • (1995) Lancet , vol.345 , pp. 1398-1402
    • Hoogerbrugge, P.M.1    Brouwer, O.F.2    Bordigoni, P.3
  • 12
    • 84861548052 scopus 로고    scopus 로고
    • Emerging concepts in haematopoietic cell transplantation
    • Li HW, Sykes M. Emerging concepts in haematopoietic cell transplantation. Nat. Rev. Immunol. 12, 403-416 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 403-416
    • Li, H.W.1    Sykes, M.2
  • 13
    • 58149384550 scopus 로고    scopus 로고
    • Graft-versus-leukemia effects of transplantation and donor lymphocytes
    • Kolb HJ. Graft-versus-leukemia effects of transplantation and donor lymphocytes. Blood 112, 4371-4383 (2008).
    • (2008) Blood , vol.112 , pp. 4371-4383
    • Kolb, H.J.1
  • 14
    • 33847332477 scopus 로고    scopus 로고
    • Novel strategies for the treatment and diagnosis of graft-versus-host-disease
    • Ferrara JL. Novel strategies for the treatment and diagnosis of graft-versus-host-disease. Best Pract. Res. Clin. Haematol. 20, 91-97 (2007).
    • (2007) Best Pract. Res. Clin. Haematol. , vol.20 , pp. 91-97
    • Ferrara, J.L.1
  • 15
    • 79951679002 scopus 로고    scopus 로고
    • Co-infusion of ex vivo-expanded, parental MSCs prevents life-Threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation
    • Bernardo ME, Ball LM, Cometa AM et al. Co-infusion of ex vivo-expanded, parental MSCs prevents life-Threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation. Bone Marrow Transplant. 46, 200-207 (2011).
    • (2011) Bone Marrow Transplant. , vol.46 , pp. 200-207
    • Bernardo, M.E.1    Ball, L.M.2    Cometa, A.M.3
  • 16
    • 85047693606 scopus 로고    scopus 로고
    • Current and emerging strategies for the prevention of graft-versus-host disease
    • Choi SW, Reddy P. Current and emerging strategies for the prevention of graft-versus-host disease. Nat. Rev. Clin. Oncol. 11, 536-547 (2014).
    • (2014) Nat. Rev. Clin. Oncol. , vol.11 , pp. 536-547
    • Choi, S.W.1    Reddy, P.2
  • 17
    • 84859173432 scopus 로고    scopus 로고
    • History of hematopoietic stem cell transplantation: Evolution and perspectives
    • Gratwohl A, Niederwieser D. History of hematopoietic stem cell transplantation: evolution and perspectives. Transplant. Dermatol.43, 81-90 (2012).
    • (2012) Transplant. Dermatol , vol.43 , pp. 81-90
    • Gratwohl, A.1    Niederwieser, D.2
  • 18
    • 65349091115 scopus 로고    scopus 로고
    • Graft-versushost disease: A complex long-Term side effect of hematopoietic stem cell transplant
    • Barton-Burke M, Dwinell DM, Kafkas L et al. Graft-versushost disease: a complex long-Term side effect of hematopoietic stem cell transplant. Oncology (Williston Park) 22, 31-45 (2008).
    • (2008) Oncology (Williston Park) , vol.22 , pp. 31-45
    • Barton-Burke, M.1    Dwinell, D.M.2    Kafkas, L.3
  • 19
    • 84875524917 scopus 로고    scopus 로고
    • Dissecting graft-versus-leukemia from graft-versus-host-disease using novel strategies
    • Warren EH, Deeg HJ. Dissecting graft-versus-leukemia from graft-versus-host-disease using novel strategies. Tissue Antigens 81, 183-193 (2013).
    • (2013) Tissue Antigens , vol.81 , pp. 183-193
    • Warren, E.H.1    Deeg, H.J.2
  • 20
    • 84873423706 scopus 로고    scopus 로고
    • Concise review: Acute graft-versus-host disease: Immunobiology, prevention, and treatment
    • Sung AD, Chao NJ. Concise review: acute graft-versus-host disease: immunobiology, prevention, and treatment. Stem Cells Transl. Med. 2, 25-32 (2013).
    • (2013) Stem Cells Transl. Med. , vol.2 , pp. 25-32
    • Sung, A.D.1    Chao, N.J.2
  • 21
    • 84888198344 scopus 로고    scopus 로고
    • Advances in the treatment of acute graft-versus-host disease
    • Qian L, Wu Z, Shen J. Advances in the treatment of acute graft-versus-host disease. J. Cell. Mol. Med. 17, 966-975 (2013).
    • (2013) J. Cell. Mol. Med. , vol.17 , pp. 966-975
    • Qian, L.1    Wu, Z.2    Shen, J.3
  • 22
    • 80855144804 scopus 로고    scopus 로고
    • Th1 and Th17 join forces for acute GvHD
    • Teshima T. Th1 and Th17 join forces for acute GvHD. Blood 118, 4765-4767 (2011).
    • (2011) Blood , vol.118 , pp. 4765-4767
    • Teshima, T.1
  • 23
    • 84899667712 scopus 로고    scopus 로고
    • Deviated balance between Th1 and Th17 cells exacerbates acute graft-versus-host disease in mice
    • Pan B, Zhang Y, Sun Y et al. Deviated balance between Th1 and Th17 cells exacerbates acute graft-versus-host disease in mice. Cytokine 68, 69-75 (2014).
    • (2014) Cytokine , vol.68 , pp. 69-75
    • Pan, B.1    Zhang, Y.2    Sun, Y.3
  • 24
    • 79953123445 scopus 로고    scopus 로고
    • Effector CD4+ T cells, the cytokines they generate, and GvHD: Something old and something new
    • Coghill JM, Sarantopoulos S, Moran TP, Murphy WJ, Blazar BR, Serody JS. Effector CD4+ T cells, the cytokines they generate, and GvHD: something old and something new. Blood 117, 3268-3276 (2011).
    • (2011) Blood , vol.117 , pp. 3268-3276
    • Coghill, J.M.1    Sarantopoulos, S.2    Moran, T.P.3    Murphy, W.J.4    Blazar, B.R.5    Serody, J.S.6
  • 25
    • 16644379996 scopus 로고    scopus 로고
    • Higher mortality after allogeneic peripheral-blood transplantation compared with bone marrow in children and adolescents: The histocompatibility and alternate stem cell source working committee of the international bone marrow transplant registry
    • Eapen M, Horowitz MM, Klein JP et al. Higher mortality after allogeneic peripheral-blood transplantation compared with bone marrow in children and adolescents: the Histocompatibility and Alternate Stem Cell Source Working Committee of the International Bone Marrow Transplant Registry. J. Clin. Oncol. 22, 4872-4880 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 4872-4880
    • Eapen, M.1    Horowitz, M.M.2    Klein, J.P.3
  • 26
    • 0023836654 scopus 로고
    • Antigen CD34+ marrow cells engraft lethally irradiated baboons
    • Berenson RJ, Andrews RG, Bensinger WI et al. Antigen CD34+ marrow cells engraft lethally irradiated baboons. J. Clin. Invest. 81, 951-955 (1988).
    • (1988) J. Clin. Invest. , vol.81 , pp. 951-955
    • Berenson, R.J.1    Andrews, R.G.2    Bensinger, W.I.3
  • 27
    • 0025258439 scopus 로고
    • Transplantation potential of peripheral blood stem cells induced by granulocyte colony-stimulating factor
    • Molineux G, Pojda Z, Hampson IN, Lord BI, Dexter TM. Transplantation potential of peripheral blood stem cells induced by granulocyte colony-stimulating factor. Blood 76, 2153-2158 (1990).
    • (1990) Blood , vol.76 , pp. 2153-2158
    • Molineux, G.1    Pojda, Z.2    Hampson, I.N.3    Lord, B.I.4    Dexter, T.M.5
  • 28
    • 79958815896 scopus 로고    scopus 로고
    • Many mechanisms mediating mobilization: An alliterative review
    • Hoggatt J, Pelus LM. Many mechanisms mediating mobilization: an alliterative review. Curr. Opin. Hematol. 18, 231-238 (2011).
    • (2011) Curr. Opin. Hematol. , vol.18 , pp. 231-238
    • Hoggatt, J.1    Pelus, L.M.2
  • 29
    • 0028903242 scopus 로고
    • Transplantation of allogeneic peripheral blood stem cells mobilized by recombinant human granulocyte colonystimulating factor
    • Bensinger WI, Weaver CH, Appelbaum FR et al. Transplantation of allogeneic peripheral blood stem cells mobilized by recombinant human granulocyte colonystimulating factor. Blood 85, 1655-1658 (1995).
    • (1995) Blood , vol.85 , pp. 1655-1658
    • Bensinger, W.I.1    Weaver, C.H.2    Appelbaum, F.R.3
  • 30
    • 0028913975 scopus 로고
    • Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor)
    • Schmitz N, Dreger P, Suttorp M et al. Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor). Blood 85, 1666-1672 (1995).
    • (1995) Blood , vol.85 , pp. 1666-1672
    • Schmitz, N.1    Dreger, P.2    Suttorp, M.3
  • 31
    • 0033566347 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation from unrelated donors: A comparison with marrow transplantation
    • Ringden O, Remberger M, Runde V et al. Peripheral blood stem cell transplantation from unrelated donors: a comparison with marrow transplantation. Blood 94, 455-464 (1999).
    • (1999) Blood , vol.94 , pp. 455-464
    • Ringden, O.1    Remberger, M.2    Runde, V.3
  • 32
    • 84889583837 scopus 로고    scopus 로고
    • Plerixafor ondemand combined with chemotherapy and granulocyte colony-stimulating factor: Significant improvement in peripheral blood stem cells mobilization and harvest with no increase in costs
    • Milone G, Martino M, Spadaro A et al. Plerixafor ondemand combined with chemotherapy and granulocyte colony-stimulating factor: significant improvement in peripheral blood stem cells mobilization and harvest with no increase in costs. Br. J. Haematol. 164, 113-123 (2014).
    • (2014) Br. J. Haematol. , vol.164 , pp. 113-123
    • Milone, G.1    Martino, M.2    Spadaro, A.3
  • 33
    • 78651347616 scopus 로고    scopus 로고
    • Plerixafor plus granulocyte CSF can mobilize hematopoietic stem cells from multiple myeloma and lymphoma patients failing previous mobilization attempts: EU compassionate use data
    • Duarte RF, Shaw BE, Marín P et al. Plerixafor plus granulocyte CSF can mobilize hematopoietic stem cells from multiple myeloma and lymphoma patients failing previous mobilization attempts: EU compassionate use data. Bone Marrow Transplant. 46, 52-58 (2011).
    • (2011) Bone Marrow Transplant. , vol.46 , pp. 52-58
    • Duarte, R.F.1    Shaw, B.E.2    Marín, P.3
  • 34
    • 0035905908 scopus 로고    scopus 로고
    • Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers
    • Bensinger WI, Martin PJ, Storer B et al. Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers. N. Engl. J. Med. 344, 175-181 (2001).
    • (2001) N. Engl. J. Med. , vol.344 , pp. 175-181
    • Bensinger, W.I.1    Martin, P.J.2    Storer, B.3
  • 35
    • 0036720739 scopus 로고    scopus 로고
    • A randomized multicenter comparison of bone marrow and peripheral blood in recipients of matched sibling allogeneic transplants for myeloid malignancies
    • Couban S, Simpson DR, Barnett MJ et al. A randomized multicenter comparison of bone marrow and peripheral blood in recipients of matched sibling allogeneic transplants for myeloid malignancies. Blood 100, 1525-1531 (2002).
    • (2002) Blood , vol.100 , pp. 1525-1531
    • Couban, S.1    Simpson, D.R.2    Barnett, M.J.3
  • 36
    • 0035880789 scopus 로고    scopus 로고
    • Acute and chronic graft-versus-host disease after allogeneic peripheral-blood stem-cell and bone marrow transplantation: A meta-Analysis
    • Cutler C, Giri S, Jeyapalan S, Paniagua D, Viswanathan A, Antin JH. Acute and chronic graft-versus-host disease after allogeneic peripheral-blood stem-cell and bone marrow transplantation: a meta-Analysis. J. Clin. Oncol. 19, 3685-3691 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3685-3691
    • Cutler, C.1    Giri, S.2    Jeyapalan, S.3    Paniagua, D.4    Viswanathan, A.5    Antin, J.H.6
  • 37
    • 0031454790 scopus 로고    scopus 로고
    • Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graft-versus-host disease
    • Storek J, Gooley T, Siadak M et al. Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graft-versus-host disease. Blood 90, 4705-4709 (1997).
    • (1997) Blood , vol.90 , pp. 4705-4709
    • Storek, J.1    Gooley, T.2    Siadak, M.3
  • 38
    • 11244251714 scopus 로고    scopus 로고
    • Increased risk of extensive chronic graft-versushost disease after allogeneic peripheral blood stem cell transplantation using unrelated donors
    • Remberger M, Beelen DW, Fauser A, Basara N, Basu O, Ringden O. Increased risk of extensive chronic graft-versushost disease after allogeneic peripheral blood stem cell transplantation using unrelated donors. Blood 105, 548-551 (2005).
    • (2005) Blood , vol.105 , pp. 548-551
    • Remberger, M.1    Beelen, D.W.2    Fauser, A.3    Basara, N.4    Basu, O.5    Ringden, O.6
  • 40
    • 84930011644 scopus 로고    scopus 로고
    • In: Hematopoietic Cell Transplantation (2nd Edition). Thomas ED, Blume KG, Forman SJ, Malden MA (Eds). Blackwell Science, Oxford, England
    • Howe CWS, Radde-Stepaniak T. Hematopoietic cell donor registries. In: Hematopoietic Cell Transplantation (2nd Edition). Thomas ED, Blume KG, Forman SJ, Malden MA (Eds). Blackwell Science, Oxford, England, 503-512 (1999).
    • (1999) Hematopoietic Cell Donor Registries , pp. 503-512
    • Howe, C.W.S.1    Radde-Stepaniak, T.2
  • 42
    • 75149155592 scopus 로고    scopus 로고
    • History of cord blood transplantation
    • Gluckman E. History of cord blood transplantation. Bone Marrow Transplant. 44, 621-626 (2009).
    • (2009) Bone Marrow Transplant. , vol.44 , pp. 621-626
    • Gluckman, E.1
  • 43
    • 0345537461 scopus 로고
    • Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells
    • Broxmeyer HE, Gordon GW, HAngoc G et al. Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc. Natl Acad. Sci. USA 86, 3828-3832 (1989).
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 3828-3832
    • Broxmeyer, H.E.1    Gordon, G.W.2    Hangoc, G.3
  • 44
    • 66349110894 scopus 로고    scopus 로고
    • Cord blood stem cells for hematopoietic stem cell transplantation in the UK: How big should the bank be?
    • Querol S, Mufti GJ, Marsh SG et al. Cord blood stem cells for hematopoietic stem cell transplantation in the UK: how big should the bank be? Haematologica 94, 536-541 (2009).
    • (2009) Haematologica , vol.94 , pp. 536-541
    • Querol, S.1    Mufti, G.J.2    Marsh, S.G.3
  • 45
    • 0028957813 scopus 로고
    • Phenotypic analysis of functional T-lymphocyte subtypes and natural killer cells in human cord blood: Relevance to umbilical cord blood transplantation
    • Han P, Hodge G, Story C, Xu X. Phenotypic analysis of functional T-lymphocyte subtypes and natural killer cells in human cord blood: relevance to umbilical cord blood transplantation. Br. J. Haematol. 89, 733-740 (1995).
    • (1995) Br. J. Haematol. , vol.89 , pp. 733-740
    • Han, P.1    Hodge, G.2    Story, C.3    Xu, X.4
  • 46
    • 11244268818 scopus 로고    scopus 로고
    • Cord blood CD4(+) CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
    • Godfrey WR, Spoden DJ, Ge YG et al. Cord blood CD4(+) CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood 105, 750-758 (2005).
    • (2005) Blood , vol.105 , pp. 750-758
    • Godfrey, W.R.1    Spoden, D.J.2    Ge, Y.G.3
  • 47
    • 0033786310 scopus 로고    scopus 로고
    • Current status of umbilical cord blood hematopoietic stem cell transplantation
    • Gluckman E. Current status of umbilical cord blood hematopoietic stem cell transplantation. Exp. Hematol. 28, 1197-1205 (2000).
    • (2000) Exp. Hematol. , vol.28 , pp. 1197-1205
    • Gluckman, E.1
  • 48
    • 4143150812 scopus 로고    scopus 로고
    • Assessment of optimal size and composition of the US National Registry of hematopoietic stem cell donors
    • Kollman C, Abella E, Baitty RL et al. Assessment of optimal size and composition of the US National Registry of hematopoietic stem cell donors. Transplantation 78, 89-95 (2004).
    • (2004) Transplantation , vol.78 , pp. 89-95
    • Kollman, C.1    Abella, E.2    Baitty, R.L.3
  • 50
    • 0035859239 scopus 로고    scopus 로고
    • Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors
    • Barker JN, Weisdorf DJ, Wagner JE. Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors. N. Engl. J. Med. 344, 1870-1871 (2001).
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1870-1871
    • Barker, J.N.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 51
    • 12844273651 scopus 로고    scopus 로고
    • Transplantation of 2 partially HLA matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy
    • Barker JN, Weisdorf DJ, DeFor TE et al. Transplantation of 2 partially HLA matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy. Blood 105, 1343-1347 (2005).
    • (2005) Blood , vol.105 , pp. 1343-1347
    • Barker, J.N.1    Weisdorf, D.J.2    Defor, T.E.3
  • 52
    • 84885934963 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation: The first 25 years and beyond
    • Ballen KK, Gluckman E, Broxmeyer HE. Umbilical cord blood transplantation: the first 25 years and beyond. Blood 122, 491-498 (2013).
    • (2013) Blood , vol.122 , pp. 491-498
    • Ballen, K.K.1    Gluckman, E.2    Broxmeyer, H.E.3
  • 54
    • 84864295344 scopus 로고    scopus 로고
    • New strategies for haploidentical transplantation
    • Oevermann L, Handgretinger R. New strategies for haploidentical transplantation. Pediatr. Res. 71, 418-426 (2012).
    • (2012) Pediatr. Res. , vol.71 , pp. 418-426
    • Oevermann, L.1    Handgretinger, R.2
  • 55
    • 43449091559 scopus 로고    scopus 로고
    • HLAhaploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide
    • Luznik L, O'Donnell PV, Symons HJ et al. HLAhaploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide. Biol. Blood Marrow Transplant. 14, 641-650 (2008).
    • (2008) Biol. Blood Marrow Transplant. , vol.14 , pp. 641-650
    • Luznik, L.1    O'donnell, P.V.2    Symons, H.J.3
  • 56
    • 0036045174 scopus 로고    scopus 로고
    • Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide
    • O'Donnell PV, Luznik L, Jones RJ et al. Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide. Biol. Blood Marrow Transplant. 8, 377-386 (2002).
    • (2002) Biol. Blood Marrow Transplant. , vol.8 , pp. 377-386
    • O'donnell, P.V.1    Luznik, L.2    Jones, R.J.3
  • 57
    • 84871925179 scopus 로고    scopus 로고
    • Unmanipulated haploidentical bone marrow transplantation and posttransplantation cyclophosphamide for hematologic malignancies after myeloablative conditioning
    • Raiola AM, Dominietto A, Ghiso A et al. Unmanipulated haploidentical bone marrow transplantation and posttransplantation cyclophosphamide for hematologic malignancies after myeloablative conditioning. Biol. Blood Marrow Transplant. 19, 117-122 (2013).
    • (2013) Biol. Blood Marrow Transplant. , vol.19 , pp. 117-122
    • Raiola, A.M.1    Dominietto, A.2    Ghiso, A.3
  • 58
    • 84929288353 scopus 로고    scopus 로고
    • A survey on unmanipulated haploidentical hematopoietic stem cell transplantation in adults with acute leukemia
    • doi:10.1038/leu.2014.336 Epub ahead of print
    • Piemontese S, Ciceri F, Labopin M et al. A survey on unmanipulated haploidentical hematopoietic stem cell transplantation in adults with acute leukemia. Leukemia doi:10.1038/leu.2014.336 (2014) (Epub ahead of print).
    • (2014) Leukemia
    • Piemontese, S.1    Ciceri, F.2    Labopin, M.3
  • 59
    • 0032533228 scopus 로고    scopus 로고
    • Optimizing outcome after unrelated marrow transplantation by comprehensive matching of HLA class i and II alleles in the donor and recipient
    • Petersdorf EW, Gooley TA, Anasetti C et al. Optimizing outcome after unrelated marrow transplantation by comprehensive matching of HLA class I and II alleles in the donor and recipient. Blood 92, 3515-3520 (1998).
    • (1998) Blood , vol.92 , pp. 3515-3520
    • Petersdorf, E.W.1    Gooley, T.A.2    Anasetti, C.3
  • 60
    • 7244243895 scopus 로고    scopus 로고
    • Limits of HLA mismatching in unrelated hematopoietic cell transplantation
    • Petersdorf EW, Anasetti C, Martin PJ et al. Limits of HLA mismatching in unrelated hematopoietic cell transplantation. Blood 104, 2976-2980 (2004).
    • (2004) Blood , vol.104 , pp. 2976-2980
    • Petersdorf, E.W.1    Anasetti, C.2    Martin, P.J.3
  • 61
    • 9244256765 scopus 로고    scopus 로고
    • Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia
    • Laughlin MJ, Eapen M, Rubinstein P et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N. Engl. J. Med. 351, 2265-2275 (2004).
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2265-2275
    • Laughlin, M.J.1    Eapen, M.2    Rubinstein, P.3
  • 62
    • 84930322558 scopus 로고    scopus 로고
    • One million haemopoietic stem-cell transplants: A retrospective observational study
    • Gratwohl A et al. One million haemopoietic stem-cell transplants: a retrospective observational study. Lancet Haematology. 2(3), e91-e100 (2015).
    • (2015) Lancet Haematology. , vol.2 , Issue.3 , pp. e91-e100
    • Gratwohl, A.1
  • 63
    • 77951623928 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation: A global perspective
    • Gratwohl A, Baldomero H, Aljurf M et al. Hematopoietic stem cell transplantation: a global perspective. JAMA 303, 1617-1624 (2010).
    • (2010) JAMA , vol.303 , pp. 1617-1624
    • Gratwohl, A.1    Baldomero, H.2    Aljurf, M.3
  • 64
    • 84885396982 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation activity in Europe
    • Gratwohl A, Baldomero H, Passweg J. Hematopoietic stem cell transplantation activity in Europe. Curr. Opin. Hematol. 20, 485-493 (2013).
    • (2013) Curr. Opin. Hematol. , vol.20 , pp. 485-493
    • Gratwohl, A.1    Baldomero, H.2    Passweg, J.3
  • 65
    • 78650199305 scopus 로고    scopus 로고
    • Hematopoietic SCT activity in Asia: A report from the Asia-Pacific Blood and Marrow Transplantation Group
    • Yoshimi A, Suzuki R, Atsuta Y et al. Hematopoietic SCT activity in Asia: a report from the Asia-Pacific Blood and Marrow Transplantation Group. Bone Marrow Transplant. 45, 1682-1691 (2010).
    • (2010) Bone Marrow Transplant. , vol.45 , pp. 1682-1691
    • Yoshimi, A.1    Suzuki, R.2    Atsuta, Y.3
  • 67
    • 45749156098 scopus 로고    scopus 로고
    • Acute GvHD: Pathogenesis and classification
    • Ball LM, Egeler RM. Acute GvHD: pathogenesis and classification. Bone Marrow Transplant. 41(Suppl. 2), S58-S64 (2008)
    • (2008) Bone Marrow Transplant. , vol.41 , pp. S58-S64
    • Ball, L.M.1    Egeler, R.M.2
  • 68
    • 84859173432 scopus 로고    scopus 로고
    • History of hematopoietic stem cell transplantation: Evolution and perspectives
    • Gratwohl A, Niederwieser D. History of hematopoietic stem cell transplantation: evolution and perspectives. Curr. Probl. Dermatol. 43, 81-90 (2012).
    • (2012) Curr. Probl. Dermatol. , vol.43 , pp. 81-90
    • Gratwohl, A.1    Niederwieser, D.2
  • 73
    • 84930004900 scopus 로고    scopus 로고
    • Cannabidiol-An innovative strategy for graft versus host disease prevention
    • Shpilberg O, Herscovici C, Dreyer J et al. Cannabidiol-An innovative strategy for graft versus host disease prevention. Blood 122, 3299 (2013).
    • (2013) Blood , vol.122 , Issue.3299
    • Shpilberg, O.1    Herscovici, C.2    Dreyer, J.3
  • 74
    • 38849116977 scopus 로고    scopus 로고
    • Acute graft-versus-host disease in children
    • Jacobsohn DA. Acute graft-versus-host disease in children. Bone Marrow Transplant. 41, 215-221 (2008).
    • (2008) Bone Marrow Transplant. , vol.41 , pp. 215-221
    • Jacobsohn, D.A.1
  • 75
    • 80054090049 scopus 로고    scopus 로고
    • Global and organ-specific chronic graft-versus-host disease severity according to the 2005 nih consensus criteria
    • Arai S, Jagasia M, Storer B et al. Global and organ-specific chronic graft-versus-host disease severity according to the 2005 NIH Consensus Criteria. Blood 118, 4242-4249 (2011).
    • (2011) Blood , vol.118 , pp. 4242-4249
    • Arai, S.1    Jagasia, M.2    Storer, B.3
  • 76
    • 79952624644 scopus 로고    scopus 로고
    • Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study
    • Prasad VK, Lucas KG, Kleiner GI et al. Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study. Biol. Blood Marrow Transplant. 17, 534-541 (2011).
    • (2011) Biol. Blood Marrow Transplant. , vol.17 , pp. 534-541
    • Prasad, V.K.1    Lucas, K.G.2    Kleiner, G.I.3
  • 77
    • 77954574611 scopus 로고    scopus 로고
    • Optimal management of chronic graftversus-host disease in children
    • Jacobsohn DA. Optimal management of chronic graftversus-host disease in children. Br. J. Haematol. 150, 278-292 (2010).
    • (2010) Br. J. Haematol. , vol.150 , pp. 278-292
    • Jacobsohn, D.A.1
  • 78
    • 30344461633 scopus 로고    scopus 로고
    • Pathophysiology of graft-versus-host disease
    • Ferrara JL, Reddy P. Pathophysiology of graft-versus-host disease. Semin. Hematol. 43, 3-10 (2006).
    • (2006) Semin. Hematol. , vol.43 , pp. 3-10
    • Ferrara, J.L.1    Reddy, P.2
  • 79
    • 84890236232 scopus 로고    scopus 로고
    • Genetically engineered donor T cells to optimize graft-versus-Tumor effects across MHC barriers
    • Ghosh A, Holland AM, van den Brink MR. Genetically engineered donor T cells to optimize graft-versus-Tumor effects across MHC barriers. Immunol. Rev. 257, 226-236 (2014).
    • (2014) Immunol. Rev. , vol.257 , pp. 226-236
    • Ghosh, A.1    Holland, A.M.2    Van Den Brink, M.R.3
  • 80
    • 0019861205 scopus 로고
    • Antileukemic effect of chronic graft-versus-host disease: Contribution to improved survival after allogeneic marrow transplantation
    • Weiden PL, Sullivan KM, Flournoy N, Storb R, Thomas ED. Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantation. N. Engl. J. Med. 304, 1529-1533 (1981).
    • (1981) N. Engl. J. Med. , vol.304 , pp. 1529-1533
    • Weiden, P.L.1    Sullivan, K.M.2    Flournoy, N.3    Storb, R.4    Thomas, E.D.5
  • 81
    • 17744419349 scopus 로고    scopus 로고
    • Graft-versusleukemia effects in T lineage and B lineage acute lymphoblastic leukemia
    • Passweg JR, Tiberghien P, Cahn JY et al. Graft-versusleukemia effects in T lineage and B lineage acute lymphoblastic leukemia. Bone Marrow Transplant. 21, 153-158 (1998).
    • (1998) Bone Marrow Transplant. , vol.21 , pp. 153-158
    • Passweg, J.R.1    Tiberghien, P.2    Cahn, J.Y.3
  • 82
    • 0025100777 scopus 로고
    • Graft-versusleukemia reactions after bone marrow transplantation
    • Horowitz MM, Gale RP, Sondel PM et al. Graft-versusleukemia reactions after bone marrow transplantation. Blood 75, 555-562 (1990).
    • (1990) Blood , vol.75 , pp. 555-562
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 83
    • 18844467941 scopus 로고    scopus 로고
    • T-cell depletion of bone marrow transplants for leukemia from donors other than HLA-identical siblings: Advantage of T-cell antibodies with narrow specificities
    • Champlin RE, Passweg JR, Zhang MJ et al. T-cell depletion of bone marrow transplants for leukemia from donors other than HLA-identical siblings: advantage of T-cell antibodies with narrow specificities. Blood 95, 3996-4003 (2000).
    • (2000) Blood , vol.95 , pp. 3996-4003
    • Champlin, R.E.1    Passweg, J.R.2    Zhang, M.J.3
  • 84
    • 0026049124 scopus 로고
    • T-cell depletion of HLA-identical transplants in leukemia
    • Marmont AM, Horowitz MM, Gale RP et al. T-cell depletion of HLA-identical transplants in leukemia. Blood 78, 2120-2130 (1991).
    • (1991) Blood , vol.78 , pp. 2120-2130
    • Marmont, A.M.1    Horowitz, M.M.2    Gale, R.P.3
  • 85
    • 0030965273 scopus 로고    scopus 로고
    • Use of partially mismatched related donors extends access to allogeneic marrow transplant
    • Henslee-Downey PJ, Abhyankar SH, Parrish RS et al. Use of partially mismatched related donors extends access to allogeneic marrow transplant. Blood 89, 3864-3872 (1997).
    • (1997) Blood , vol.89 , pp. 3864-3872
    • Henslee-Downey, P.J.1    Abhyankar, S.H.2    Parrish, R.S.3
  • 86
    • 0029073339 scopus 로고
    • Similar incidence of graft-versus-host disease using HLA-A-B and-DR identical unrelated bone marrow donors as with HLA-identical siblings
    • Ringden O, Remberger M, Persson U et al. Similar incidence of graft-versus-host disease using HLA-A,-B and-DR identical unrelated bone marrow donors as with HLA-identical siblings. Bone Marrow Transplant. 15, 619-625 (1995).
    • (1995) Bone Marrow Transplant. , vol.15 , pp. 619-625
    • Ringden, O.1    Remberger, M.2    Persson, U.3
  • 87
    • 79959456118 scopus 로고    scopus 로고
    • Chronic graft-versushost disease: Long-Term results from a randomized trial on graft-versus-host disease prophylaxis with or without anti-Tcell globulin ATG-Fresenius
    • Socié G, Schmoor C, Bethge WA et al. Chronic graft-versushost disease: long-Term results from a randomized trial on graft-versus-host disease prophylaxis with or without anti-Tcell globulin ATG-Fresenius. Blood 117, 6375-6382 (2011).
    • (2011) Blood , vol.117 , pp. 6375-6382
    • Socié, G.1    Schmoor, C.2    Bethge, W.A.3
  • 88
    • 84884146092 scopus 로고    scopus 로고
    • Antithymocyte globulins for post-Transplant graft-versus-host disease prophylaxis-A systematic review and meta-Analysis
    • Theurich S, Fischmann H, Chakupurakal G et al. Antithymocyte globulins for post-Transplant graft-versus-host disease prophylaxis-A systematic review and meta-Analysis. Crit. Rev. Oncol. Hematol. 88, 178-186 (2013).
    • (2013) Crit. Rev. Oncol. Hematol. , vol.88 , pp. 178-186
    • Theurich, S.1    Fischmann, H.2    Chakupurakal, G.3
  • 89
    • 33745449021 scopus 로고    scopus 로고
    • Thymoglobulin prevents chronic graft-versus-host disease, chronic lung dysfunction, and late transplant-related mortality: Longterm follow-up of a randomized trial in patients undergoing unrelated donor transplantation
    • Bacigalupo A, Lamparelli T, Barisione G et al. Thymoglobulin prevents chronic graft-versus-host disease, chronic lung dysfunction, and late transplant-related mortality: longterm follow-up of a randomized trial in patients undergoing unrelated donor transplantation. Biol. Blood Marrow Transplant. 12, 560-565 (2006).
    • (2006) Biol. Blood Marrow Transplant. , vol.12 , pp. 560-565
    • Bacigalupo, A.1    Lamparelli, T.2    Barisione, G.3
  • 90
    • 13944258549 scopus 로고    scopus 로고
    • Antilymphocyte/thymocyte globulin for graft versus host disease prophylaxis: Efficacy and side effects
    • Bacigalupo A. Antilymphocyte/thymocyte globulin for graft versus host disease prophylaxis: efficacy and side effects. Bone Marrow Transplant. 35, 225-231 (2005).
    • (2005) Bone Marrow Transplant. , vol.35 , pp. 225-231
    • Bacigalupo, A.1
  • 91
    • 3142733478 scopus 로고    scopus 로고
    • Dose study of thymoglobulin during conditioning for unrelated donor allogeneic stem-cell transplantation
    • Remberger M, Svahn BM, Mattsson J, Ringden O. Dose study of thymoglobulin during conditioning for unrelated donor allogeneic stem-cell transplantation. Transplantation 78, 122-127 (2004).
    • (2004) Transplantation , vol.78 , pp. 122-127
    • Remberger, M.1    Svahn, B.M.2    Mattsson, J.3    Ringden, O.4
  • 92
    • 84907357105 scopus 로고    scopus 로고
    • Tacrolimus/sirolimus versus tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic hematopoietic cell transplantation
    • Cutler C, Logan B, Nakamura R et al. Tacrolimus/sirolimus versus tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic hematopoietic cell transplantation. Blood 124(8), 1372-1377 (2014).
    • (2014) Blood , vol.124 , Issue.8 , pp. 1372-1377
    • Cutler, C.1    Logan, B.2    Nakamura, R.3
  • 93
    • 0024510510 scopus 로고
    • Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graftversus-host disease in patients given HLA-identical marrow grafts for leukemia: Long-Term follow-up of a controlled trial
    • Storb R, Deeg HJ, Pepe M et al. Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graftversus-host disease in patients given HLA-identical marrow grafts for leukemia: long-Term follow-up of a controlled trial. Blood 73, 1729-1734 (1989).
    • (1989) Blood , vol.73 , pp. 1729-1734
    • Storb, R.1    Deeg, H.J.2    Pepe, M.3
  • 94
    • 0022273650 scopus 로고
    • Graft-versus-host disease in dog and man: The Seattle experience
    • Storb R, Thomas ED. Graft-versus-host disease in dog and man: the Seattle experience. Immunol. Rev. 88, 215-238 (1985).
    • (1985) Immunol. Rev. , vol.88 , pp. 215-238
    • Storb, R.1    Thomas, E.D.2
  • 95
    • 84861527625 scopus 로고    scopus 로고
    • What predicts high risk acute graft-versus-host disease (GvHD) at onset? Identification of those at highest risk by a novel acute GvHD risk score
    • MacMillan ML, Defor TE, Weisdorf DJ. What predicts high risk acute graft-versus-host disease (GvHD) at onset? Identification of those at highest risk by a novel acute GvHD risk score. Br. J. Haematol. 157, 732-741 (2012).
    • (2012) Br. J. Haematol. , vol.157 , pp. 732-741
    • MacMillan, M.L.1    Defor, T.E.2    Weisdorf, D.J.3
  • 96
    • 0036048349 scopus 로고    scopus 로고
    • Response of 443 patients to steroids as primary therapy for acute graftversus-host disease: Comparison of grading systems
    • MacMillan ML, Weisdorf DJ, Wagner JE et al. Response of 443 patients to steroids as primary therapy for acute graftversus-host disease: comparison of grading systems. Biol. Blood Marrow Transplant. 8, 387-394 (2002).
    • (2002) Biol. Blood Marrow Transplant. , vol.8 , pp. 387-394
    • MacMillan, M.L.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 97
    • 0025190044 scopus 로고
    • Treatment of moderate/ severe acute graft-versus-host disease after allogeneic bone marrow transplantation: An analysis of clinical risk features and outcome
    • Weisdorf D, Haake R, Blazar B et al. Treatment of moderate/ severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood 75, 1024-1030 (1990).
    • (1990) Blood , vol.75 , pp. 1024-1030
    • Weisdorf, D.1    Haake, R.2    Blazar, B.3
  • 98
    • 84855296444 scopus 로고    scopus 로고
    • Steroid-refractory acute GVHD Predictors and outcomes
    • Westin JR, Saliba RM, De Lima M et al. Steroid-refractory acute GVHD. Predictors and outcomes. Adv. Hematol. 2011, 601953 (2011).
    • (2011) Adv. Hematol. , vol.2011 , pp. 601953
    • Westin, J.R.1    Saliba, R.M.2    De Lima, M.3
  • 99
    • 0016187133 scopus 로고
    • Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors
    • Glucksberg H, Storb R, Fefer A et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors. Transplantation 18, 295-304 (1974).
    • (1974) Transplantation , vol.18 , pp. 295-304
    • Glucksberg, H.1    Storb, R.2    Fefer, A.3
  • 100
    • 32544453971 scopus 로고    scopus 로고
    • Shared biology of GVHD and GVT effects: Potential methods of separation
    • Fowler DH. Shared biology of GVHD and GVT effects: potential methods of separation. Crit. Rev. Oncol. Hematol. 57, 225-244 (2006).
    • (2006) Crit. Rev. Oncol. Hematol. , vol.57 , pp. 225-244
    • Fowler, D.H.1
  • 101
    • 39149096837 scopus 로고    scopus 로고
    • Separation of graft-vs.-Tumor effects from graft-vs.-host disease in allogeneic hematopoietic cell transplantation
    • Rezvani AR, Storb RF. Separation of graft-vs.-Tumor effects from graft-vs.-host disease in allogeneic hematopoietic cell transplantation. J. Autoimmun. 30, 172-179 (2008).
    • (2008) J. Autoimmun. , vol.30 , pp. 172-179
    • Rezvani, A.R.1    Storb, R.F.2
  • 102
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik WD. Graft-versus-host disease. Nat. Rev. Immunol. 7, 340-352 (2007).
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 103
    • 0029952614 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation for CML: A report from the International Bone Marrow Transplant
    • Horowitz MM, Rowlings PA, Passweg JR. Allogeneic bone marrow transplantation for CML: a report from the International Bone Marrow Transplant. Registry. Bone Marrow Transplant. 17(Suppl. 3), S5-S6 (1996).
    • (1996) Registry. Bone Marrow Transplant. , vol.17 , pp. S5-S6
    • Horowitz, M.M.1    Rowlings, P.A.2    Passweg, J.R.3
  • 104
    • 9444243839 scopus 로고    scopus 로고
    • Duration of immunosuppressive treatment for chronic graft-versus-host disease
    • Stewart BL, Storer B, Storek J et al. Duration of immunosuppressive treatment for chronic graft-versus-host disease. Blood 104, 3501-3506 (2004).
    • (2004) Blood , vol.104 , pp. 3501-3506
    • Stewart, B.L.1    Storer, B.2    Storek, J.3
  • 105
    • 84879382652 scopus 로고    scopus 로고
    • Extracorporeal photopheresis versus anticytokine therapy as a second-line treatment for steroid-refractory acute GVHD: A multicenter comparative analysis
    • Jagasia M, Greinix H, Robin M et al. Extracorporeal photopheresis versus anticytokine therapy as a second-line treatment for steroid-refractory acute GVHD: a multicenter comparative analysis. Biol. Blood Marrow Transplant. 19, 1129-1133 (2013).
    • (2013) Biol. Blood Marrow Transplant. , vol.19 , pp. 1129-1133
    • Jagasia, M.1    Greinix, H.2    Robin, M.3
  • 106
    • 84856949531 scopus 로고    scopus 로고
    • Steroid-refractory acute GVHD: Lack of long-Term improved survival using new generation anticytokine treatment
    • Xhaard A, Rocha V, Bueno B et al. Steroid-refractory acute GVHD: lack of long-Term improved survival using new generation anticytokine treatment. Biol. Blood Marrow Transplant. 18, 406-413 (2012).
    • (2012) Biol. Blood Marrow Transplant. , vol.18 , pp. 406-413
    • Xhaard, A.1    Rocha, V.2    Bueno, B.3
  • 107
    • 79955539945 scopus 로고    scopus 로고
    • Attributable hospital cost and antifungal treatment of invasive fungal diseases in high-risk hematology patients: An economic modeling approach
    • Ananda-Rajah MR, Cheng A, Morrissey CO et al. Attributable hospital cost and antifungal treatment of invasive fungal diseases in high-risk hematology patients: an economic modeling approach. Antimicrob. Agents Chemother. 55, 1953-1960 (2011).
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 1953-1960
    • Ananda-Rajah, M.R.1    Cheng, A.2    Morrissey, C.O.3
  • 108
    • 84865402362 scopus 로고    scopus 로고
    • Economics of hematopoietic cell transplantation
    • Khera N, Zeliadt SB, Lee SJ. Economics of hematopoietic cell transplantation. Blood 120, 1545-1551 (2012).
    • (2012) Blood , vol.120 , pp. 1545-1551
    • Khera, N.1    Zeliadt, S.B.2    Lee, S.J.3
  • 109
    • 4644359708 scopus 로고    scopus 로고
    • Impact of HLA class i and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome
    • Flomenberg N, Baxter-Lowe LA, Confer D et al. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 104, 1923-1930 (2004).
    • (2004) Blood , vol.104 , pp. 1923-1930
    • Flomenberg, N.1    Baxter-Lowe, L.A.2    Confer, D.3
  • 110
    • 34548401754 scopus 로고    scopus 로고
    • Hematopoietic cell transplantation: Progress and obstacles
    • Devetten M, Armitage JO. Hematopoietic cell transplantation: progress and obstacles. Ann. Oncol. 18, 1450-1456 (2007).
    • (2007) Ann. Oncol. , vol.18 , pp. 1450-1456
    • Devetten, M.1    Armitage, J.O.2
  • 111
    • 52949086615 scopus 로고    scopus 로고
    • Novel drugs for the prevention and treatment of acute GVHD
    • Cutler C, Antin JH. Novel drugs for the prevention and treatment of acute GVHD. Curr. Pharm. Des. 14, 1962-1973 (2008).
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 1962-1973
    • Cutler, C.1    Antin, J.H.2
  • 113
    • 84863371821 scopus 로고    scopus 로고
    • Plasma biomarkers of lower gastrointestinal and liver acute GVHD
    • Harris AC, Ferrara JL, Braun TM et al. Plasma biomarkers of lower gastrointestinal and liver acute GVHD. Blood 119, 2960-2963 (2012).
    • (2012) Blood , vol.119 , pp. 2960-2963
    • Harris, A.C.1    Ferrara, J.L.2    Braun, T.M.3
  • 114
    • 77955902702 scopus 로고    scopus 로고
    • The best endpoint for acute GVHD treatment trials
    • MacMillan ML, DeFor TE, Weisdorf DJ. The best endpoint for acute GVHD treatment trials. Blood 115, 5412-5417 (2010).
    • (2010) Blood , vol.115 , pp. 5412-5417
    • MacMillan, M.L.1    Defor, T.E.2    Weisdorf, D.J.3
  • 115
    • 33745172172 scopus 로고    scopus 로고
    • Treatment costs and survival in patients with grades III-IV acute graftversus-host disease after allogenic hematopoietic stem cell transplantation during three decades
    • Svahn BM, Ringden O, Remberger M. Treatment costs and survival in patients with grades III-IV acute graftversus-host disease after allogenic hematopoietic stem cell transplantation during three decades. Transplantation 81, 1600-1603 (2006).
    • (2006) Transplantation , vol.81 , pp. 1600-1603
    • Svahn, B.M.1    Ringden, O.2    Remberger, M.3
  • 116
    • 38449087129 scopus 로고    scopus 로고
    • Pluristem therapeutics, inc
    • Prather W. Pluristem Therapeutics, Inc. Regen. Med. 3, 117-122 (2008).
    • (2008) Regen. Med. , vol.3 , pp. 117-122
    • Prather, W.1
  • 118
    • 84906730217 scopus 로고    scopus 로고
    • Deciphering the therapeutic stem cell strategies of large and midsize pharmaceutical firms
    • Vertes AA. Deciphering the therapeutic stem cell strategies of large and midsize pharmaceutical firms. Regen. Med. 9, 479-495 (2014).
    • (2014) Regen. Med. , vol.9 , pp. 479-495
    • Vertes, A.A.1
  • 120
    • 84907597699 scopus 로고    scopus 로고
    • Progress and prospects for engineered T cell therapies
    • Qasim W, Thrasher AJ. Progress and prospects for engineered T cell therapies. Br. J. Haematol. 166, 818-829 (2014).
    • (2014) Br. J. Haematol. , vol.166 , pp. 818-829
    • Qasim, W.1    Thrasher, A.J.2
  • 121
    • 84885099905 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Sensors and switchers of inflammation
    • Bernardo ME, Fibbe WE. Mesenchymal stromal cells: sensors and switchers of inflammation. Cell Stem Cell 13, 392-402 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 392-402
    • Bernardo, M.E.1    Fibbe, W.E.2
  • 122
    • 79751504754 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Mechanisms of inflammation
    • Singer NG, Caplan AI. Mesenchymal stem cells: mechanisms of inflammation. Annu. Rev. Pathol. 6, 457-478 (2011).
    • (2011) Annu. Rev. Pathol. , vol.6 , pp. 457-478
    • Singer, N.G.1    Caplan, A.I.2
  • 123
    • 84891140189 scopus 로고    scopus 로고
    • Cord blood transplantation: Can we make it better? Front
    • Metheny L, Caimi P, de Lima M. Cord blood transplantation: can we make it better? Front. Oncol. 3, 228 (2013).
    • (2013) Oncol. , vol.3 , Issue.228
    • Metheny, L.1    Caimi, P.2    De Lima, M.3
  • 124
    • 84901378544 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stromal cells to treat complications following allogeneic stem cell transplantation
    • Battiwalla M, Barrett AJ. Bone marrow mesenchymal stromal cells to treat complications following allogeneic stem cell transplantation. Tissue Eng. Part B Rev. 20, 211-217 (2014).
    • (2014) Tissue Eng. Part B Rev. , vol.20 , pp. 211-217
    • Battiwalla, M.1    Barrett, A.J.2
  • 125
    • 84925883417 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy and acute graft-versus-host disease: A review
    • Amorin B, Alegretti AP, Valim V et al. Mesenchymal stem cell therapy and acute graft-versus-host disease: a review. Hum. Cell. 27, 137-150 (2014).
    • (2014) Hum. Cell. , vol.27 , pp. 137-150
    • Amorin, B.1    Alegretti, A.P.2    Valim, V.3
  • 126
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
    • Ringden O, Uzunel M, Rasmusson I et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 81, 1390-1397 (2006).
    • (2006) Transplantation , vol.81 , pp. 1390-1397
    • Ringden, O.1    Uzunel, M.2    Rasmusson, I.3
  • 127
    • 84930000273 scopus 로고    scopus 로고
    • The potential of cytotherapeutics in hematologic reconstitution and in the treatment and prophylaxis of graftversus-host disease Chapter II: Emerging transformational cytotherapies
    • Vertes AA. The potential of cytotherapeutics in hematologic reconstitution and in the treatment and prophylaxis of graftversus-host disease. Chapter II: Emerging transformational cytotherapies. Regen. Med. 10(3) 345-373 (2015).
    • (2015) Regen. Med. , vol.10 , Issue.3 , pp. 345-373
    • Vertes, A.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.